Exposure to Toxic Metals and Persistent Organic Pollutants in Inuit Children Attending Childcare Centers in Nunavik, Canada

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• 作者：Huguette Turgeon O鈥橞rien ; Rosanne Blanchet ; Doris Gagn茅 ; Julie Lauzi猫re ; Carole V茅zina ; 脡milie Vaissi猫re ; Pierre Ayotte ; Serge D茅ry
• 刊名：Environmental Science & Technology (ES&T)
• 出版年：2012
• 出版时间：April 17, 2012
• 年：2012
• 卷：46
• 期：8
• 页码：4614-4623
• 全文大小：326K
• 年卷期：v.46,no.8(April 17, 2012)
• ISSN：1520-5851

文摘

Arctic populations are exposed to substantial levels of environmental contaminants that can negatively affect children鈥檚 health and development. Moreover, emerging contaminants have never been assessed in Inuit children. In this study, we document the biological exposure to toxic metals and legacy and emerging persistent organic pollutants (POPs) of 155 Inuit children (mean age 25.2 months) attending childcare centers in Nunavik. Blood samples were analyzed to determine concentrations of mercury, lead, polychlorinated biphenyls (PCBs), pesticides, brominated flame retardants [e.g., polybrominated diphenyl ethers (PBDEs)] and perfluoroalkyl and polyfluoroalkyl substances [PFASs; e.g. perfluorooctanesulfonate (PFOS) and perfluorooctane (PFOA)]. Lead [geometric mean (GM) 0.08 渭mol/L], PCB-153 (GM 22.2 ng/g of lipid), BDE-47 (GM 184 ng/g of lipid), PFOS (GM 3369 ng/L), and PFOA (GM 1617 ng/L) were detected in all samples. Mercury (GM 9.8 nmol/L) was detected in nearly all blood samples (97%). Levels of metals and legacy POPs are consistent with the decreasing trend observed in Nunavik and in the Arctic. PBDE levels were higher than those observed in many children and adolescents around the world but lower than those reported in some U.S. cities. PFOS were present in lower concentrations than in Nunavimmiut adults. There is a clear need for continued biomonitoring of blood contaminant levels in this population, particularly for PBDEs and PFASs.