Copper-Catalyzed Regioselective C–H Sulfonylation of 8-Aminoquinolines

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• 作者：Jun Wei ; Jingxing Jiang ; Xinsheng Xiao ; Dongen Lin ; Yuanfu Deng ; Zhuofeng Ke ; Huanfeng Jiang ; Wei Zeng
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：February 5, 2016
• 年：2016
• 卷：81
• 期：3
• 页码：946-955
• 全文大小：563K
• ISSN：1520-6904

文摘

Copper(I)-catalyzed 5-sulfonation of quinolines via bidentate-chelation assistance has been developed. The reaction is compatible with a wide range of quinoline substrates and arylsulfonyl chlorides. Experimental and theoretical (DFT) investigation implicated that a single-electron-transfer process is involved in this sulfonylation transformation.