Northeast Yunnan Province is one of the important lead and zinc ore accumulative zones while Yuhucun lead-zinc deposit is one of the ore containing stratum in Yuhucun Formation in the region. The conclusion is that lead-zinc deposit’s composition came from multiple-source and the formative processes was multi-period and multi-stage according to the research on Pb isotope, S isotope and H-O isotope of lead-zinc deposit in Yuhucun Formation in Northeast Yunnan Province. Pb came mostly from earth crust with a small amount coming from the mantle and orogenic belt. S originated from marine with a small amount from biological action. The main metallogenic fluid came from meteorological water and a small amount maybe came from Magmatic water.
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