The 34 cm sediment core, which was recovered from Taro Co, southwestern Tibetan Plateau, was investigated. The multiple indicators in the sediment including the contents of total organic carbon, inorganic carbon, total nitrogen, trace elements and n-alkanes and the ratio of carbon and nitrogen contents were measured. The results showed that the climatic and environmental changes of Taro Co Region could be divided into three obvious stages. The cold and warm alternately recorded by the sediments in Taro Co were highly consistent with that recorded by ice core in Guliya and lake sediments in Qinghai Lake. However, there were differences in the beginning and end years of the stages.