化疗联合放疗治疗晚期口腔癌临床价值研究
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摘要
目的探究化疗联合放疗治疗晚期口腔癌的临床价值。方法选取70例晚期口腔癌患者分组研究,两组基础治疗方法相同,观察组加以化疗治疗,对比两组患者治疗疗效、毒副反应、生存率。结果观察组患者治疗疗效、毒副反应、生存率及治疗满意率情况明显优于对照组(P <0.05)。结论放化疗联合治疗晚期口腔癌疗效佳,患者不良反应可耐受,安全可靠,且患者满意率高,可提升1年生存率。
Objective To explore the clinical value of chemotherapy combined with radiotherapy in the treatment of advanced oral cancer. Methods 70 cases of patients with advanced oral cancer group were andomly divided into two groups. The control group and the study group had same basic treatment, and the study group received chemotherapy. Treatment efficacy, toxicity and survival rate were cpmpared between two group. Results The treatment group was better than the control in Treatment efficacy, toxicity and survival rate, there were statistical significance(P < 0.05). Conclusion The combination of radiotherapy and chemotherapy in the treatment of advanced oral cancer has good efficacy, the adverse reactions of patients can be tolerated, safe and reliable, and the patients have a high rate of satisfaction, which can improve the one-year survival rate.
Objective To explore the clinical value of chemotherapy combined with radiotherapy in the treatment of advanced oral cancer. Methods 70 cases of patients with advanced oral cancer group were andomly divided into two groups. The control group and the study group had same basic treatment, and the study group received chemotherapy. Treatment efficacy, toxicity and survival rate were cpmpared between two group. Results The treatment group was better than the control in Treatment efficacy, toxicity and survival rate, there were statistical significance(P < 0.05). Conclusion The combination of radiotherapy and chemotherapy in the treatment of advanced oral cancer has good efficacy, the adverse reactions of patients can be tolerated, safe and reliable, and the patients have a high rate of satisfaction, which can improve the one-year survival rate.
引文
[1]钟来平,孙坚,郭伟,等.256例局部晚期口腔癌的生存分析[J].中国肿瘤临床,2015,42(4):217-221.
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[7]沈想,张潇雯,朱江,等.术前诱导化疗联合术后放疗治疗口腔癌的疗效[J].江苏医药,2017,43(16):1165-1167.
[8]吴训,蒙宁,巫家晓,等.晚期口腔鳞癌术后同期联合放化疗与单纯放疗疗效的比较观察[J].广西医科大学学报,2015,32(4):567-569.
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[10]周丽娜.基于LC-MS代谢组学的口腔癌化疗效果评价研究[A].中国化学会、国家自然科学基金委员会.中国化学会第二届全国质谱分析学术报告会会议摘要集[C].中国化学会、国家自然科学基金委员会,2015:1.
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[12]Marta GN,Riera R,Bossi P,张凌.口腔癌患者术前诱导化疗联合或不联合术后放疗:系统回顾和meta分析[J].中国口腔颌面外科杂志,2015,13(5):424.
[13]徐娟,闫俊杰.顺铂、5-氟尿嘧啶持续动脉灌注化疗对口腔癌的临床疗效及安全性评价[J].中国临床药理学杂志,2015,31(15):1491-1493.
[2]刘晓楠,张文超.口腔癌相关micro RNA研究进展[J].天津医药,2015,43(5):570-572.
[3]张陈平.口腔癌的多学科协作诊治模式[J].中国肿瘤临床,2015,42(16):787-790.
[4]陈国栋,卿安蓉.近距离腔内照射联合外照射治疗控制口腔癌术后复发的临床效果评价[J].医学综述,2015,21(6):1144-1145,1150,1153.
[5]雷竹,黄立敏,廖加群,等.经皮穿刺胃造瘘术在局部晚期口腔癌患者中的应用[J].医药前沿,2017,7(7):105-106.
[6]黄桂林.选择性动脉灌注化疗在口腔癌治疗中的进展[J].口腔颌面外科杂志,2015,25(5):317-320.
[7]沈想,张潇雯,朱江,等.术前诱导化疗联合术后放疗治疗口腔癌的疗效[J].江苏医药,2017,43(16):1165-1167.
[8]吴训,蒙宁,巫家晓,等.晚期口腔鳞癌术后同期联合放化疗与单纯放疗疗效的比较观察[J].广西医科大学学报,2015,32(4):567-569.
[9]黄桂林.选择性动脉灌注化疗在口腔癌治疗中的进展[J].口腔颌面外科杂志,2015,25(05):317-320.
[10]周丽娜.基于LC-MS代谢组学的口腔癌化疗效果评价研究[A].中国化学会、国家自然科学基金委员会.中国化学会第二届全国质谱分析学术报告会会议摘要集[C].中国化学会、国家自然科学基金委员会,2015:1.
[11]刘晓楠,卓姗姗,岳玖玲,等.新辅助化疗在局部晚期口腔癌中的疗效分析[J].天津医科大学学报,2015,21(5):408-411.
[12]Marta GN,Riera R,Bossi P,张凌.口腔癌患者术前诱导化疗联合或不联合术后放疗:系统回顾和meta分析[J].中国口腔颌面外科杂志,2015,13(5):424.
[13]徐娟,闫俊杰.顺铂、5-氟尿嘧啶持续动脉灌注化疗对口腔癌的临床疗效及安全性评价[J].中国临床药理学杂志,2015,31(15):1491-1493.