不同空腹血糖浓度下糖尿病足溃疡愈合速度的观察分析
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摘要
目的观察分析不同空腹血糖浓度下糖尿病足溃疡愈合速度。方法监测不同空腹血糖下,溃疡愈合速度,并作统计学分析。结果当糖尿病病人空腹血糖在6.9 mmol/l以下时,溃疡愈合速度为0.42 mm/天;当空腹血糖在6.9~8.0 mmol/l时,溃疡愈合速度为0.41 mm/天;当空腹血糖大于8 mmol/l时,溃疡愈合速度为0.25mm/天。对照组(非糖尿病组),溃疡愈合速度为0.45 mm/天。结论糖尿病病人空腹血糖水平低于8.0 mmol/l时,溃疡愈合速度与非糖尿病病人无差异;当血糖高于8.0 mmol/l时,溃疡愈合速度明显降低。
Objective: To observe and analyze the healing rate of diabetic foot ulcers under different fasting blood glucose levels. Methods: The healing rate of ulcer under different fasting blood glucose was monitored and analyzed statistically. Results: When fasting blood glucose was below 6. 9 mmol/l,ulcer healing rate was 0. 42 mm/day; when fasting blood glucose was between 6. 9 ~ 8. 0 mmol/l,ulcer healing rate was 0. 41 mm/day; when fasting blood glucose was above 8. 0 mmol/l,ulcer healing rate was 0. 25 mm/day. In control group( non-diabetic group),the healing rate of ulcer was 0. 45 mm/days.Conclusion: When the fasting blood glucose level of diabetic patients is lower than 8. 0 mmol/l,the healing rate of ulcer is no different from that of non-diabetic patients.
Objective: To observe and analyze the healing rate of diabetic foot ulcers under different fasting blood glucose levels. Methods: The healing rate of ulcer under different fasting blood glucose was monitored and analyzed statistically. Results: When fasting blood glucose was below 6. 9 mmol/l,ulcer healing rate was 0. 42 mm/day; when fasting blood glucose was between 6. 9 ~ 8. 0 mmol/l,ulcer healing rate was 0. 41 mm/day; when fasting blood glucose was above 8. 0 mmol/l,ulcer healing rate was 0. 25 mm/day. In control group( non-diabetic group),the healing rate of ulcer was 0. 45 mm/days.Conclusion: When the fasting blood glucose level of diabetic patients is lower than 8. 0 mmol/l,the healing rate of ulcer is no different from that of non-diabetic patients.
引文
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[2]黄瑶,钱培芬.糖尿病足分级系统及其评价.中华烧伤杂志,2012,28(1):47-50.
[3]冯帅南,黄宏,张波,等.小鼠全层皮肤创伤愈合过程中基质细胞衍生因子-1及其受体CXCR4基因表达的研究.感染、炎症、修复,2008,9(3):142-145.
[4]王齐,朱冠娅,牛轶雯,等.阻断糖基化终末产物受体效应对小鼠糖尿病创面炎症反应的影响.中华损伤与修复杂志(电子版),2017,12(4):254-261.
[5]张莹.糖尿病足内皮功能紊乱机制的研究进展.检验医学.2013.28(10)948-951.
[6]魏民,易世宏,陈存举.难愈合性糖尿病足溃疡组织巨噬细胞数量和血管形成生长因子C表达的研究.世界最新医学信息文摘(连续型电子期刊),2015,(62):1-2.
[7]主父中印,林樾,刘恿铂,等.高葡萄糖高游离脂肪酸对皮肤成纤维细胞β-连环蛋白表达的影响.中华实验外科杂志,2014,31(1):57-60.