2009—2017年甘肃省陇南市手足口病流行病学特征分析
|
摘要
目的了解2009—2017年甘肃省陇南市手足口病流行病学特征,为制定科学有效的防控策略提供参考依据。方法疫情资料来源于国家疾病监测信息报告管理系统,用描述流行病学方法分析2009—2017年甘肃省陇南市手足口病的流行特征。结果 2009—2017年陇南市共报告手足口病7 247例,年平均报告发病率为30.80/10万,其中两当县最高(109.41/10万)、礼县最低(8.80/10万);每年发病基本呈现单峰分布、4—7月高发,报告发病率男性(34.79/10万)高于女性(26.44/10万),差异有统计学意义(χ~2=133.32,P<0.001);以散居儿童和托幼儿童为主,5岁及以下儿童占90.12%,报告发病率5岁及以下儿童(375.59/10万)高于6岁及以上人群(3.29/10万),差异有统计学意义(χ~2=504.15,P<0.001);以EV71病原为主、占46.75%,不同年度优势毒株交替出现。结论甘肃省陇南市手足口病时间、地区和人群分布均有一定的特征;在高发季节对重点地区应加强监测、做好宣传教育,提高适龄儿童预防EV71疫苗的接种率,降低手足口病发病率。
Objective To understand the epidemiological characteristics of hand-foot-mouth disease(HFMD) in Longnan city of Gansu province from 2009 to 2017, and provide reference for formulating scientific and effective prevention and control strategies. Methods The data of HFMD was collected from Diseases Reporting Information System, and the epidemic characteristics were analyzed with descriptively epidemiological methods. Results There were 7 247 cases of HFMD reported in Longnan during 2009 to 2017, with average annual incidence of 30.80/100 000, the highest annual incidence in Liangdang county(109.41/100 000) and the lowest in Li county(8.80/100 000). The incidence was higher from April to July with a single peak distribution and higher(χ~2=133.32, P<0.001) in the male(34.79/100 000) than in the female(26.44/100 000). The cases were mainly in scattered and kindergarten children, 90.12% of the cases were of 5 year-old and younger. The reported incidence in the children under 5 years of age(375.59/100 000) was higher than that in the children of 6 years of age and over(3.29/100 000), with statistical difference(χ~2=504.15, P<0.001). EV71 was the main pathogen,accounting for 46.75%, the dominant strains alternated in different years. Conclusions The epidemic of HFMD shows some characteristics of the onset time, distribution of region and population in Longnan city, Gansu province. The surveillance, publicity and education should be strengthened in the key areas in high occurrence season. The vaccination rate of EV71 should be increased to decrease the incidence of HFMD.
Objective To understand the epidemiological characteristics of hand-foot-mouth disease(HFMD) in Longnan city of Gansu province from 2009 to 2017, and provide reference for formulating scientific and effective prevention and control strategies. Methods The data of HFMD was collected from Diseases Reporting Information System, and the epidemic characteristics were analyzed with descriptively epidemiological methods. Results There were 7 247 cases of HFMD reported in Longnan during 2009 to 2017, with average annual incidence of 30.80/100 000, the highest annual incidence in Liangdang county(109.41/100 000) and the lowest in Li county(8.80/100 000). The incidence was higher from April to July with a single peak distribution and higher(χ~2=133.32, P<0.001) in the male(34.79/100 000) than in the female(26.44/100 000). The cases were mainly in scattered and kindergarten children, 90.12% of the cases were of 5 year-old and younger. The reported incidence in the children under 5 years of age(375.59/100 000) was higher than that in the children of 6 years of age and over(3.29/100 000), with statistical difference(χ~2=504.15, P<0.001). EV71 was the main pathogen,accounting for 46.75%, the dominant strains alternated in different years. Conclusions The epidemic of HFMD shows some characteristics of the onset time, distribution of region and population in Longnan city, Gansu province. The surveillance, publicity and education should be strengthened in the key areas in high occurrence season. The vaccination rate of EV71 should be increased to decrease the incidence of HFMD.
引文
[1]中华人民共和国国家卫生和计划生育委员会.手足口病预防控制指南(2014版)[R].北京:中华人民共和国国家卫生和计划生育委员会,2014.
[2]中华人民共和国国家卫生和计划生育委员会.卫生部关于将手足口病纳入法定传染病管理的通知[EB/OL].(2008-05-02)[2018-09-07].http://www.nhfpc.gov.cn/zwgkzt/wsbysj/200805/34766.shtml.
[3]于晓楠,忻丽菁,杨吉星,等.2010-2016年上海市虹口区手足口流行病学及病原学特征分析[J].中国预防医学杂志,2018,19(1):58-63.
[4]曹洋,刘莹莹,于秋丽,等.2010-2015年河北省手足口病流行特征分析[J].疾病监测,2017,32(1):29-33.
[5]刘静雯,耿进妹,陈纯,等.2011-2015年广州市手足口病流行病学特征及病原学监测分析[J].现代预防医学,2017,44(5):772-777.
[6]张华一,徐立莉,李得恩,等.2012-2016年青海省手足口病流行病学特征分析[J].医学动物防制,(下转第82页)(上接第21页)2018,34(10):932-934,938.
[7]史恒越,安宣宁,代晓泽,等.2009-2015年辽宁省阜新市手足口病流行病学特征分析[J].预防医学情报杂志,2017,33(3):252-257.
[8]ONOZUKA D,HASHIZUME M.The influence of temperature and humidity on the incidence of hand,foot,and mouth disease in Japan[J].Science of The Total Environment,2011,410:119-125.
[9]陈建华,张勇,武海卓,等.甘肃省2013-2016年手足口病病原学监测分析[J].病毒学报,2017,33(4):505-511.
[10]崔亚奇.2010-2015年我国手足口病流行特征分析[J].宜宾学院学报,2018,18(6):113-115.
[11]葛锦荣,孙霞霞,朱彩蓉,等.2011-2017年宁波市北仑区手足口病流行特征及病原学特征分析[J].预防医学情报杂志,2018,34(9):1222-1228.
[12]张玲,王玲,王涛,等.2007-2015年淄博市手足口病流行趋势及病原学特征分析[J].中国病原生物学杂志,2017,12(4):359-362.
[13]李萌,张清慧,郭晓芹,等.2012-2016年上海市松江区手足口病流行病学及病原学特征分析[J].现代预防医学,2017,44(18):3421-3425.
[14]陈少明,杜中华,邱丽,等.海南省手足口病重症病例危险因素的1∶1匹配病例对照研究[J].中华疾病控制杂志,2018,22(8):830-832,858.
[15]黄甜,李琼芬,沈秀莲,等.云南省手足口病重症病例危险因素分析[J].现代预防医学,2017,44(6):1115-1119.
[2]中华人民共和国国家卫生和计划生育委员会.卫生部关于将手足口病纳入法定传染病管理的通知[EB/OL].(2008-05-02)[2018-09-07].http://www.nhfpc.gov.cn/zwgkzt/wsbysj/200805/34766.shtml.
[3]于晓楠,忻丽菁,杨吉星,等.2010-2016年上海市虹口区手足口流行病学及病原学特征分析[J].中国预防医学杂志,2018,19(1):58-63.
[4]曹洋,刘莹莹,于秋丽,等.2010-2015年河北省手足口病流行特征分析[J].疾病监测,2017,32(1):29-33.
[5]刘静雯,耿进妹,陈纯,等.2011-2015年广州市手足口病流行病学特征及病原学监测分析[J].现代预防医学,2017,44(5):772-777.
[6]张华一,徐立莉,李得恩,等.2012-2016年青海省手足口病流行病学特征分析[J].医学动物防制,(下转第82页)(上接第21页)2018,34(10):932-934,938.
[7]史恒越,安宣宁,代晓泽,等.2009-2015年辽宁省阜新市手足口病流行病学特征分析[J].预防医学情报杂志,2017,33(3):252-257.
[8]ONOZUKA D,HASHIZUME M.The influence of temperature and humidity on the incidence of hand,foot,and mouth disease in Japan[J].Science of The Total Environment,2011,410:119-125.
[9]陈建华,张勇,武海卓,等.甘肃省2013-2016年手足口病病原学监测分析[J].病毒学报,2017,33(4):505-511.
[10]崔亚奇.2010-2015年我国手足口病流行特征分析[J].宜宾学院学报,2018,18(6):113-115.
[11]葛锦荣,孙霞霞,朱彩蓉,等.2011-2017年宁波市北仑区手足口病流行特征及病原学特征分析[J].预防医学情报杂志,2018,34(9):1222-1228.
[12]张玲,王玲,王涛,等.2007-2015年淄博市手足口病流行趋势及病原学特征分析[J].中国病原生物学杂志,2017,12(4):359-362.
[13]李萌,张清慧,郭晓芹,等.2012-2016年上海市松江区手足口病流行病学及病原学特征分析[J].现代预防医学,2017,44(18):3421-3425.
[14]陈少明,杜中华,邱丽,等.海南省手足口病重症病例危险因素的1∶1匹配病例对照研究[J].中华疾病控制杂志,2018,22(8):830-832,858.
[15]黄甜,李琼芬,沈秀莲,等.云南省手足口病重症病例危险因素分析[J].现代预防医学,2017,44(6):1115-1119.