维生素D与结直肠癌的相关性研究进展
摘要
<正>结直肠癌是高发性恶性肿瘤之一,最新调查数据显示美国每年新发结直肠癌大约134 490例,死亡49 190例,发病率和病死率在男性和女性中均高居第3位[1]。结直肠癌具体病因仍不明确,普遍认为与环境因素、生活饮食方式及遗传因素共同作用有关,其中高脂、高蛋白饮食为较明确的影响因素,饮食中胡
引文
[1]SIEGEL RL,MILLER KD,JEMAL A.Cancer statistics,2016[J].CA:a Cancer J Clin,2016,66(1):7-30.
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[3]GARLAND CF.Do sunlight and vitamin D reduce the likelihood of colon cancer[J].Int J Epidemiol,1980,9(3):227-231.
[4]BINTINTAN VV.Vitamin D as a potential therapeutic target and prognostic marker for colorectal cancer[J].E Bio Med,2018,31:11-12.
[5]黄靖,张彩霞.维生素D与恶性肿瘤的关系[J/CD].肿瘤代谢与营养电子杂志,2016,3(4):243-249.
[6]曹雨娜,张虹.维生素D抗肿瘤作用的研究进展[J].中国临床药学杂志,2014,23(2):129-132.
[7]HE Y,TIMOFEEVA M,FARRINGTON SM,et al.Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk:a large Mendelian randomisation study[J].BMC Medicine,2018,16(1):142-149.
[8]SUN J.The role of vitamin D and vitamin D receptors in colon cancer[J].Clin Translat Gastroenterol,2017,8(6):100-103.
[9]GURAYA SY.The association of vitamin D deficiency with colorectal cancer:a wake-up call for physicians and health authorities[J].Mid East J Cancer,2017,8(2):65-68.
[10]BECKETT EL,LE GRAS K,MARTIN C,et al.Vitamin D receptor polymorphisms relate to risk of adenomatous polyps in a sexspecific manner[J].Nutr Cancer,2016,68(2):193-200.
[11]MOSTOWSKA A,SAJDAK S,PAWLIk P,et al.Polymorphic variants in the vitamin D pathway genes and the risk of ovarian cancer among non-carriers of BRCA1/BRCA2mutations[J].Oncol Lett,2016,11(2):1181-1182.
[12]DOOLEY J,LAGOU V,HEIRMAN N,et al.Murine pancreatic acinar cell carcinoma growth kinetics are independent of dietary vitamin D deficiency or supplementation[J].Front Oncol,2017,7(1):133-137.
[13]MAATY MAAE,WOLFL S.Vitamin D as a novel regulator of tumor metabolism:insights on potential mechanisms and implications for anti-cancer therapy[J].Int J Molecul Sci,2017,18(10):2184-2188.
[14]HUMMEL DM,THIEM U,HBAUS J,et al.Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis[J].J Steroid Biochem Mol Biol,2013,136(2):284-2888.
[15]QU B,ZHAN H,HAO Q.Role of circulating and supplemental calcium and vitamin D in the occurrence and development of colorectal adenoma or colorectal cancer[J/OL].J Clin Gastroenterol,(2017-01-27)[2019-01-05].https://www.ncbi.nlm.nih.gov/pubmed/28134636.
[16]MORALESOYARVIDE V,MEYERHARDT JA,NG K.Vitamin D and physical activity in patients with colorectal cancer:epidemiological evidence and therapeutic implications[J].Cancer J,2016,22(3):223-231.
[17]CARLBERG C.Molecular endocrinology of vitamin D on the epigenome level[J].Molecul Cellul Endocrinol,2017,453(1):14-21.
[18]PEREIRA F,LARRIBA MJ,MUNOZ A.Vitamin D and colon cancer[J].Endocr Relat Cancer,2012,19(3):51-71.
[19]WESA KM,SEGAL NH,CRONIN AM,et al.Serum 25-hydroxy vitamin D and survival in advanced colorectal cancer:a retrospective analysis[J].Nutrit Cancer Internat J,2015,67(3):424-430.
[20]SONG M,NISHIHARA R,WANG M,et al.Plasma 25-hydroxyvitamin D and colorectal cancer risk according to tumour immunity status[J].Gut,2016,65(2):296-304.
[21]WANG J,THINGHOLM LB,SKIECEVICIENE J,et al.Genome-wide association analysis identifies variation in vitamin Dreceptor and other host factors influencing the gut microbiota[J].Nat Genet,2016,48(16):1396-1406.
[22]BELLELI A,SHANY S,LEVY J,et al.A protective role of 1,25-dihydroxyvitamin D3in chemically induced rat colon carcinogenesis[J].Carcinogenesis,1992,13(12):2293-2298.
[23]于慧会,魏立璇,刘运泳,等.25-羟基维生素D与结直肠癌关系的Meta分析[J].肿瘤防治研究,2015,42(4):394-398.
[24]BARON JA,BARRY EL,MOTTT LA,et al.A trial of calcium and vitamin D for the prevention of colorectal adenomas[J].NEngl J Med,2015,373:1519-1530.
[25]ANTUNAC ZG,BARSIC I,LIBRENJAK N,et al.Vitamin D supplementation and survival in metastatic colorectal cancer[J].Nutrit Cancer,2018,70(9):1-9.
[26]ZHANG X,GIOVANNUCCI E.Calcium and vitamin D for the prevention of colorectal adenomas[J].N Engl J Med,2016,374:791-792.
[27]ARGJIRA JS.Vitamin D and colorectal carcinogenesis:a critical evaluation of vitamin D clinical overview[M/OL].(2017-04-02)[2019-01-24].https://www.researchgate.net/publication/317151445_Vitamin_D_and_Colorectal_Carcinogenesis.
[28]DUFFY MJ,MURRAY A,SYNNOTT NC,et al.Vitamin D analogues:potential use in cancer treatment[J].Criti Rev Oncol,2017,112(2):190-199.
[29]MILCZAREK M,ROSINSKA S,PSURSKI M,et al.Combined colonic cancer treatment with vitamin D analogs and irinotecan or oxaliplatin[J].Anticancer Res,2013,33(4):433-444.
[2]SUN YY,KIM YS,LEE JE,et al.Dietary protein and fat intake in relation to risk of colorectal adenoma in Korean[J].Medicine,2016,95(49):5453-5456.
[3]GARLAND CF.Do sunlight and vitamin D reduce the likelihood of colon cancer[J].Int J Epidemiol,1980,9(3):227-231.
[4]BINTINTAN VV.Vitamin D as a potential therapeutic target and prognostic marker for colorectal cancer[J].E Bio Med,2018,31:11-12.
[5]黄靖,张彩霞.维生素D与恶性肿瘤的关系[J/CD].肿瘤代谢与营养电子杂志,2016,3(4):243-249.
[6]曹雨娜,张虹.维生素D抗肿瘤作用的研究进展[J].中国临床药学杂志,2014,23(2):129-132.
[7]HE Y,TIMOFEEVA M,FARRINGTON SM,et al.Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk:a large Mendelian randomisation study[J].BMC Medicine,2018,16(1):142-149.
[8]SUN J.The role of vitamin D and vitamin D receptors in colon cancer[J].Clin Translat Gastroenterol,2017,8(6):100-103.
[9]GURAYA SY.The association of vitamin D deficiency with colorectal cancer:a wake-up call for physicians and health authorities[J].Mid East J Cancer,2017,8(2):65-68.
[10]BECKETT EL,LE GRAS K,MARTIN C,et al.Vitamin D receptor polymorphisms relate to risk of adenomatous polyps in a sexspecific manner[J].Nutr Cancer,2016,68(2):193-200.
[11]MOSTOWSKA A,SAJDAK S,PAWLIk P,et al.Polymorphic variants in the vitamin D pathway genes and the risk of ovarian cancer among non-carriers of BRCA1/BRCA2mutations[J].Oncol Lett,2016,11(2):1181-1182.
[12]DOOLEY J,LAGOU V,HEIRMAN N,et al.Murine pancreatic acinar cell carcinoma growth kinetics are independent of dietary vitamin D deficiency or supplementation[J].Front Oncol,2017,7(1):133-137.
[13]MAATY MAAE,WOLFL S.Vitamin D as a novel regulator of tumor metabolism:insights on potential mechanisms and implications for anti-cancer therapy[J].Int J Molecul Sci,2017,18(10):2184-2188.
[14]HUMMEL DM,THIEM U,HBAUS J,et al.Prevention of preneoplastic lesions by dietary vitamin D in a mouse model of colorectal carcinogenesis[J].J Steroid Biochem Mol Biol,2013,136(2):284-2888.
[15]QU B,ZHAN H,HAO Q.Role of circulating and supplemental calcium and vitamin D in the occurrence and development of colorectal adenoma or colorectal cancer[J/OL].J Clin Gastroenterol,(2017-01-27)[2019-01-05].https://www.ncbi.nlm.nih.gov/pubmed/28134636.
[16]MORALESOYARVIDE V,MEYERHARDT JA,NG K.Vitamin D and physical activity in patients with colorectal cancer:epidemiological evidence and therapeutic implications[J].Cancer J,2016,22(3):223-231.
[17]CARLBERG C.Molecular endocrinology of vitamin D on the epigenome level[J].Molecul Cellul Endocrinol,2017,453(1):14-21.
[18]PEREIRA F,LARRIBA MJ,MUNOZ A.Vitamin D and colon cancer[J].Endocr Relat Cancer,2012,19(3):51-71.
[19]WESA KM,SEGAL NH,CRONIN AM,et al.Serum 25-hydroxy vitamin D and survival in advanced colorectal cancer:a retrospective analysis[J].Nutrit Cancer Internat J,2015,67(3):424-430.
[20]SONG M,NISHIHARA R,WANG M,et al.Plasma 25-hydroxyvitamin D and colorectal cancer risk according to tumour immunity status[J].Gut,2016,65(2):296-304.
[21]WANG J,THINGHOLM LB,SKIECEVICIENE J,et al.Genome-wide association analysis identifies variation in vitamin Dreceptor and other host factors influencing the gut microbiota[J].Nat Genet,2016,48(16):1396-1406.
[22]BELLELI A,SHANY S,LEVY J,et al.A protective role of 1,25-dihydroxyvitamin D3in chemically induced rat colon carcinogenesis[J].Carcinogenesis,1992,13(12):2293-2298.
[23]于慧会,魏立璇,刘运泳,等.25-羟基维生素D与结直肠癌关系的Meta分析[J].肿瘤防治研究,2015,42(4):394-398.
[24]BARON JA,BARRY EL,MOTTT LA,et al.A trial of calcium and vitamin D for the prevention of colorectal adenomas[J].NEngl J Med,2015,373:1519-1530.
[25]ANTUNAC ZG,BARSIC I,LIBRENJAK N,et al.Vitamin D supplementation and survival in metastatic colorectal cancer[J].Nutrit Cancer,2018,70(9):1-9.
[26]ZHANG X,GIOVANNUCCI E.Calcium and vitamin D for the prevention of colorectal adenomas[J].N Engl J Med,2016,374:791-792.
[27]ARGJIRA JS.Vitamin D and colorectal carcinogenesis:a critical evaluation of vitamin D clinical overview[M/OL].(2017-04-02)[2019-01-24].https://www.researchgate.net/publication/317151445_Vitamin_D_and_Colorectal_Carcinogenesis.
[28]DUFFY MJ,MURRAY A,SYNNOTT NC,et al.Vitamin D analogues:potential use in cancer treatment[J].Criti Rev Oncol,2017,112(2):190-199.
[29]MILCZAREK M,ROSINSKA S,PSURSKI M,et al.Combined colonic cancer treatment with vitamin D analogs and irinotecan or oxaliplatin[J].Anticancer Res,2013,33(4):433-444.