用卡前列素氨丁三醇预防宫缩乏力性产后出血的效果分析
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摘要
目的:研究用卡前列素氨丁三醇预防宫缩乏力性产后出血的效果。方法:选取在四川省合江县人民医院进行分娩的86例存在发生宫缩乏力性产后出血高危因素的产妇作为研究对象。将其分为OBS组和CON组(43例/组)。在两组产妇将胎儿娩出后,为其均应用缩宫素进行预防宫缩乏力性产后出血的治疗。在此基础上,为OBS组产妇加用卡前列素氨丁三醇进行预防宫缩乏力性产后出血的治疗。然后对比两组产妇的产后出血量、凝血酶原时间、平均动脉压和不良反应的发生情况。结果:OBS组产妇产后30min内的出血量、产后2h内的出血量和产后24h内的出血量均少于CON组产妇,治疗后其凝血酶原时间短于CON组产妇,其平均动脉压和不良反应的发生率均低于CON组产妇,P <0.05。结论:用卡前列素氨丁三醇预防宫缩乏力性产后出血的效果显著,能够有效地减少产妇的产后出血量,改善其凝血功能,降低其平均动脉压和不良反应的发生率。
Objective: To study the effect of kaprostatin on the prevention of anaemic postpartum hemorrhage. Methods: 86 cases of parturient women with high risk factors of dystrophic postpartum hemorrhage were selected as the research objects in hejiang county people's hospital of sichuan province. It was divided into OBS group and CON group(43 cases/group). After delivering the fetus in both groups, oxytocin was used to prevent the postpartum hemorrhage caused by uterine fatigue. On this basis, caprostatin was added to the OBS group for the prevention of uterine fatigue postpartum hemorrhage. Then the postpartum blood loss, prothrombin time, mean arterial pressure and adverse reactions were compared between the two groups. Results: the blood loss within 30 min postpartum, 2 h postpartum and 24 h postpartum in OBS group were all less than that in CON group, the prothrombin time was shorter after treatment than that in CON group, and the average arterial pressure and incidence of adverse reactions were lower than that in CON group(P < 0.05). Conclusion: caprostatin can effectively reduce postpartum bleeding, improve coagulation function, and reduce the incidence of average arterial pressure and adverse reactions.
Objective: To study the effect of kaprostatin on the prevention of anaemic postpartum hemorrhage. Methods: 86 cases of parturient women with high risk factors of dystrophic postpartum hemorrhage were selected as the research objects in hejiang county people's hospital of sichuan province. It was divided into OBS group and CON group(43 cases/group). After delivering the fetus in both groups, oxytocin was used to prevent the postpartum hemorrhage caused by uterine fatigue. On this basis, caprostatin was added to the OBS group for the prevention of uterine fatigue postpartum hemorrhage. Then the postpartum blood loss, prothrombin time, mean arterial pressure and adverse reactions were compared between the two groups. Results: the blood loss within 30 min postpartum, 2 h postpartum and 24 h postpartum in OBS group were all less than that in CON group, the prothrombin time was shorter after treatment than that in CON group, and the average arterial pressure and incidence of adverse reactions were lower than that in CON group(P < 0.05). Conclusion: caprostatin can effectively reduce postpartum bleeding, improve coagulation function, and reduce the incidence of average arterial pressure and adverse reactions.
引文
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[4]俞泓,周紫琼,孙颖.卡前列素氨丁三醇注射液治疗宫缩乏力性产后出血的临床疗效分析[J].中国医药科学.2015,5(9):90-92.
[5]和振芬.卡前列素氨丁三醇注射液在宫缩乏力性产后出血治疗中的应用[J].陕西医学杂志.2015,44(6):746-747.
[2]崔海,崔春媚,林燕.国产与进口卡前列素氨丁三醇注射液治疗宫缩乏力性产后出血的临床疗效[J].中国药物经济学.2015,10(6):58-59.
[3]杨茵梅,廖丹.卡前列素氨丁三醇注射液应用于宫缩乏力产后出血的临床分析[J].中国医药导报.2015,36(18):58-61.
[4]俞泓,周紫琼,孙颖.卡前列素氨丁三醇注射液治疗宫缩乏力性产后出血的临床疗效分析[J].中国医药科学.2015,5(9):90-92.
[5]和振芬.卡前列素氨丁三醇注射液在宫缩乏力性产后出血治疗中的应用[J].陕西医学杂志.2015,44(6):746-747.