云南省德宏州2017年婚检人群HIV感染率及影响因素分析
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摘要
目的了解2017年德宏州进行婚前医学检查人群中的(human immunodeficiency virus,HIV)感染状况并分析其影响因素。方法整理2017年德宏州的婚检人群数据,描述分析其人口学特征,并使用单因素和多因素Logistic回归分析相应的影响因素。结果 2017年德宏州共有21 875例婚检者参与HIV检测,有98人确证为HIV抗体阳性,HIV感染率为0. 45%,男性感染率为0. 47%(52/10 955),女性感染率为0. 42%(46/10 920)。98例感染者中有20名感染者为首次新报告阳性,感染途径以性传播感染为主,占81. 63%(80/98)。Logistic多因素回归分析显示:年龄、民族、是否吸毒是婚检人群HIV感染的影响因素。相对于25岁以下人群,31～、41～岁年龄组人群HIV感染危险性增加(OR=3. 78,95%CI:1. 81～7. 89,P <0. 001; OR=3. 95,95%CI:1. 72～9. 08,P=0. 001);傣族、景颇族的HIV感染危险性高于汉族(OR=1. 86,95%CI:1. 06～3. 29,P=0. 031; OR=3. 25,95%CI:1. 81～5. 84,P <0. 001)。吸毒人群的HIV感染危险性远高于不吸毒人群(OR=926. 76,95%CI:271. 65～3161. 71,P <0. 001)。结论年龄、民族、是否吸毒为婚检人群HIV感染的影响因素,需要对危险因素采取针对性措施。HIV感染途径以性传播感染为主,通过婚检可以有效发现并控制HIV传播。
Objective To understand the prevalence of HIV infection and its influencing factors in the premarital physical examination population in Dehong Prefecture,Yunnan Province,2017. Methods The data of people receiving premarital medical examination was collected,the demographic characteristics was described and the related factors was analyzed by Logistic regression. Results There were21 875 participants receiving premarital medical examination in Dehong. 98( 0. 45%) participants were confirmed positive for HIV and male infection rate was 0. 47%( 52/10 955) and female was 0. 42%( 46/10 920). Among the 98 patients,20 patients were infected in the first time,and main route was sexual transmission accounting for 81. 63%( 80/98). Logistic multivariate regression analysis showed that age,ethnicity and drug use were the influencing factors for premarital couples infecting HIV. The risk of HIV infection in 31-40 and 41-50 years old group was higher than the people under 25 years old group( OR = 3. 78,95% CI: 1. 81-7. 89,P < 0. 001; OR = 3. 95,95% CI: 1. 72-9. 08,P = 0. 001).The infection risk of Dai and Jingpo ethnic group was higher than that of the Han ethnic( OR = 1. 86,95% CI: 1. 06-3. 29,P = 0. 031; OR = 3. 25,95% CI: 1. 81-5. 84,P < 0. 001). The risk of infection among drug users was much higher than non-drug users( OR = 926. 76,95% CI: 271. 65-3 161. 71,P< 0. 001). Conclusion Age,ethnicity,and drug use are influencing factors of HIV infection among premarital couples. Targeted measures need to be taken against risk factors. HIV infection is mainly transmitted by sexual transmission. It can be effectively detected and controlled through premarital medical examination.
Objective To understand the prevalence of HIV infection and its influencing factors in the premarital physical examination population in Dehong Prefecture,Yunnan Province,2017. Methods The data of people receiving premarital medical examination was collected,the demographic characteristics was described and the related factors was analyzed by Logistic regression. Results There were21 875 participants receiving premarital medical examination in Dehong. 98( 0. 45%) participants were confirmed positive for HIV and male infection rate was 0. 47%( 52/10 955) and female was 0. 42%( 46/10 920). Among the 98 patients,20 patients were infected in the first time,and main route was sexual transmission accounting for 81. 63%( 80/98). Logistic multivariate regression analysis showed that age,ethnicity and drug use were the influencing factors for premarital couples infecting HIV. The risk of HIV infection in 31-40 and 41-50 years old group was higher than the people under 25 years old group( OR = 3. 78,95% CI: 1. 81-7. 89,P < 0. 001; OR = 3. 95,95% CI: 1. 72-9. 08,P = 0. 001).The infection risk of Dai and Jingpo ethnic group was higher than that of the Han ethnic( OR = 1. 86,95% CI: 1. 06-3. 29,P = 0. 031; OR = 3. 25,95% CI: 1. 81-5. 84,P < 0. 001). The risk of infection among drug users was much higher than non-drug users( OR = 926. 76,95% CI: 271. 65-3 161. 71,P< 0. 001). Conclusion Age,ethnicity,and drug use are influencing factors of HIV infection among premarital couples. Targeted measures need to be taken against risk factors. HIV infection is mainly transmitted by sexual transmission. It can be effectively detected and controlled through premarital medical examination.
引文
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[8]龚渝蓉,杨跃诚,段松,等.德宏州2006-2009年婚检人群HIV感染率及其影响因素研究[J].中华疾病控制杂志,2011,15(4):295-299.Gong YR,Yang YC,Duan S,et al.Prevalence and correlates of HIV infections among people participating in premarital examinations from2006 to 2009 in Dehong Prefecture[J].Chin J Dis Control Prev,2011,15(4):295-299.
[9]龚渝蓉,杨玲,高洁,等.云南省德宏州2010年婚检人群的HIV感染率及其影响因素[J].中国艾滋病性病,2012,18(3):156-158.DOI:10.13419/j.cnki.aids.2012.03.003.Gong YR,Yang L,Gao J,et al.HIV prevalence and risk factors among premarital couples in Dehong prefecture of Yunnan province2010[J].Chin J Aids Std,2012,18(3):156-158.DOI:10.13419/j.cnki.aids.2012.03.003.
[10]龚渝蓉,徐梦娇,杨跃诚,等.德宏州2012-2015年婚检人群的HIV感染率及其影响因素[J].中国艾滋病性病,2017,23(5):405-408,413.DOI:10.13419/j.cnki.aids.2017.05.10.Gong YR,Xu MJ,Yang YC,et al.Prevalence and influencing factors of HIV infections among people reveiving premarital phusical examination in Dehong prefecture during 2012-2015[J].Chin J Aids Std,2017,23(5):405-408,413.DOI:10.13419/j.cnki.aids.2017.05.10.
[11]杨志俊,唐作红,李春霞,等.少数民族与汉族注射吸毒人群艾滋病哨点监测结果分析[J].中国艾滋病性病,2012,18(3):174-176.DOI:10.13419/j.cnki.aids.2012.03.017.Yang ZJ,Tang ZH,Li CX,et al.Analysis of monitoring data of AIDS sentinel points among IDUs of ethnic minorities and the Han nationality[J].Chin J Aids Std,2012,18(3):174-176.DOI:10.13419/j.cnki.aids.2012.03.017.
[12]曹艳芬,靳子义,杨跃诚,等.2010-2016年云南省德宏州艾滋病哨点吸毒人员丙型肝炎病毒感染状况及影响因素[J].中国艾滋病性病,2018,(2):135-139.DOI:10.13419/j.cnki.aids.2018.02.08.Cao YF,Jin ZY,Yang YC,et al.HCV infection status and influencing factors of drug users in AIDS outposts in Dehong prefecture,yunnan province from 2010-2016[J].Chin J Aids Std,2018,(2):135-139.DOI:10.13419/j.cnki.aids.2018.02.08.
[13]Tadesse M.Assessment of HIV discordance and associated risk factors among couples receiving HIV test in Dilla,Ethiopia[J].BMC Res Notes,2014,7:893.DOI:10.1186/1756-0500-7-893.
[14]Wu Z,Rou K,Xu C,et al.Acceptability of HIV/AIDS counseling and testing among premarital couples in China[J].Aids Educ Prev,2005,17(1):12-21.DOI:10.1521/aeap.17.1.12.58686.
[2]Hall H,Song RP,Rhodes P,et al.Estimation of HIV incidence in the United States[J].JAMA,2008,300(5):520-529.DOI:10.1001/jama.300.5.520.
[3]Granich RM,Gilks CF,Dye C,et al.Universal voluntary HIVtesting with immediate antiretroviral therapy as a strategy for elimination of HIV transmission:a mathematical model[J].Lancet,2009,373(9657):48-57.DOI:10.1016/S0140-6736(08)61697-9.
[4]中华人民共和国卫生部,联合国艾滋病规划署,世界卫生组织.2011年中国艾滋病疫情估计[J].中国艾滋病性病,2012,18(1):1-5.DOI:10.13419/j.cnki.aids.2012.01.005.Chinese Ministry of Health,UNAIDS,WHO.Estimates of the AIDS epidemic in China in 2011[J].Chin J Aids Std,2012,18(1):1-5.DOI:10.13419/j.cnki.aids.2012.01.005.
[5]项丽芬,高洁,段松,等.德宏州1992-2010年静脉注射吸毒人群艾滋病哨点监测[J].中国艾滋病性病,2013(9):673-674.DOI:10.13419/j.cnki.aids.2013.09.018.Xiang LF,Gao J,Duan S,et al.Sentinel surveillance of HIV infection among injection drug users in Dehong Prefecture,Yunnan Province from 1992 to 2010[J].Chin J Aids Std,2013(9):673-674.DOI:10.13419/j.cnki.aids.2013.09.018.
[6]杨世江,杨跃诚,叶润华,等.云南省德宏州缅甸籍HIV感染者随访管理分析[J].中华流行病学杂志,2015,36(3):265-270.DOI:10.3760/cma.j.issn.0254-6450.2015.03.016.Yang SJ,Yang YC,Ye RH,et al.Analysis of follow-up and administration of HIV-infected Burmese in Dehong prefecture of Yunnan province[J].Chin J Epidemiol,2015,36(3):265-270.DOI:10.3760/cma.j.issn.0254-6450.2015.03.016.
[7]Yi H,Mantell JE,Wu R,et al.A profile of HIV risk factors in the context of sex work environments among migrant female sex workers in Beijing,China[J].Psychology Health&Medicine,2010,15(2):172-187.DOI:10.1080/13548501003623914.
[8]龚渝蓉,杨跃诚,段松,等.德宏州2006-2009年婚检人群HIV感染率及其影响因素研究[J].中华疾病控制杂志,2011,15(4):295-299.Gong YR,Yang YC,Duan S,et al.Prevalence and correlates of HIV infections among people participating in premarital examinations from2006 to 2009 in Dehong Prefecture[J].Chin J Dis Control Prev,2011,15(4):295-299.
[9]龚渝蓉,杨玲,高洁,等.云南省德宏州2010年婚检人群的HIV感染率及其影响因素[J].中国艾滋病性病,2012,18(3):156-158.DOI:10.13419/j.cnki.aids.2012.03.003.Gong YR,Yang L,Gao J,et al.HIV prevalence and risk factors among premarital couples in Dehong prefecture of Yunnan province2010[J].Chin J Aids Std,2012,18(3):156-158.DOI:10.13419/j.cnki.aids.2012.03.003.
[10]龚渝蓉,徐梦娇,杨跃诚,等.德宏州2012-2015年婚检人群的HIV感染率及其影响因素[J].中国艾滋病性病,2017,23(5):405-408,413.DOI:10.13419/j.cnki.aids.2017.05.10.Gong YR,Xu MJ,Yang YC,et al.Prevalence and influencing factors of HIV infections among people reveiving premarital phusical examination in Dehong prefecture during 2012-2015[J].Chin J Aids Std,2017,23(5):405-408,413.DOI:10.13419/j.cnki.aids.2017.05.10.
[11]杨志俊,唐作红,李春霞,等.少数民族与汉族注射吸毒人群艾滋病哨点监测结果分析[J].中国艾滋病性病,2012,18(3):174-176.DOI:10.13419/j.cnki.aids.2012.03.017.Yang ZJ,Tang ZH,Li CX,et al.Analysis of monitoring data of AIDS sentinel points among IDUs of ethnic minorities and the Han nationality[J].Chin J Aids Std,2012,18(3):174-176.DOI:10.13419/j.cnki.aids.2012.03.017.
[12]曹艳芬,靳子义,杨跃诚,等.2010-2016年云南省德宏州艾滋病哨点吸毒人员丙型肝炎病毒感染状况及影响因素[J].中国艾滋病性病,2018,(2):135-139.DOI:10.13419/j.cnki.aids.2018.02.08.Cao YF,Jin ZY,Yang YC,et al.HCV infection status and influencing factors of drug users in AIDS outposts in Dehong prefecture,yunnan province from 2010-2016[J].Chin J Aids Std,2018,(2):135-139.DOI:10.13419/j.cnki.aids.2018.02.08.
[13]Tadesse M.Assessment of HIV discordance and associated risk factors among couples receiving HIV test in Dilla,Ethiopia[J].BMC Res Notes,2014,7:893.DOI:10.1186/1756-0500-7-893.
[14]Wu Z,Rou K,Xu C,et al.Acceptability of HIV/AIDS counseling and testing among premarital couples in China[J].Aids Educ Prev,2005,17(1):12-21.DOI:10.1521/aeap.17.1.12.58686.
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