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地震伤员输血治疗效果分析
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摘要
[目的]调查1663名地震伤员的输用治疗,了解血液成分用量和输注剂量,对提高输血疗效,指导突发事件的血液供应有意义。[方法]5月12日~6月20日期间,50家医院1663名伤员用成都市血液中心血液进行输血治疗。对伤员输血资料统计分析,了解血液品种和用量、输血剂量分布和输血方案等。[结果]1663名伤员年龄从新生婴儿至100岁老人,伤情复杂,有15种类型。骨折944人,56.7%。86%输血原因是手术。主要输用全血、红细胞悬液、冰冻血浆、血小板等。红细胞悬液和冰冻血浆合计占94%血液用量。扣除未输用人数,人均输血量为全血3.3U;红细胞悬液5.3U;血浆11.9U;血小板6.0U。最小与最大输血量相差几十倍~百倍。50%以上伤员输血剂量为2U(全血67%,红悬54%,血小板69%)。68%全血单独输用,而70%红细胞悬液、90%血浆和97%血小板是两种以上血液成分联合输血。3种血液成分输用的伤员仅31名(2%),却输用了91%血小板,19%血浆、13%红细胞悬液和10%全血。[结论]输血治疗在伤员救治中发挥了关键作用,保障血液供应具有十分重要的意义。
[Objective] To investigate the transfusion treatment among 1663 wounded people in the disaster earthquake,so as to investigate the blood composition and the dose of transfusion,so as to improve the treatment effect of transfusion and guide the blood supplement during emergency events.[Methods] 1663 wounded people in 50 hospitals were treated with transfusion from 12th May to 20th June 2008,and the data of transfusion were analyzed.The types of blood,doses,transfusion distribution and strategies were investigated.[Results] 1663 patients aged from 0 to 100 years old,and their diseases were serious,including 15 types of disease.944 patients were fractures,accounted for 56.7%.86% of people with transfusion were due to operation.The main types of blood transfusion were whole blood,red cell suspension,refrigerated plasma and blood platelet.94% of blood transfusion were red cell suspension and refrigerated plasma.The mean dose of whole blood was 3.3U,RBCs was 5.3U,plasma was 11.9U,and platelets were 6.0U.Blood transfusion doses ranged from tenfold to hundredfold.Over 50% of patients was transfused with 2U of blood(whole blood 67%,RBCs 54% and platelet 69%).68% of the whole blood was used alone,but 70% RBCs,90% plasma and 97% platelets were transfused together in patients.Only 31 patients were treated with 3 components transfusion(2%),but they consumed 91% of blood platelet,19% of plasma and 13% of red cell suspension and 10% of whole blood.[Conclusion] RBCs,frozen plasma was mainly used in transfusion,and play an important role in treatment of wounded people.Blood supply was very crucial in the medical relief during the periods of disasters.
引文
Peiris AN,Mueller RA,Smith GA,et al.Effect of a national dis-aster on blood supply and safety:the September11experience[J].JAMA,2003,289(17):2246-2253.
    S A Mujeeb,S H Jaffery.Emergency blood transfusion services af-ter the2005earthquake in pakistan[J].Emerg Med J,2007,24:22-24.
    M Sonmezoglu,N Kocak,O Oncul,et al.Effect of a major earth-quake on blood donor types and infectious disease marker rates[J].Transfusion Medicine,2005,15:93-97.

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