畜牧养殖过程中高铜添加与潜在风险
|
摘要
随着抗生素在畜牧养殖过程中禁用或减量,高铜在动物肠道中的抑菌、杀菌作用效果被放大。目前,高剂量铜添加现象较为普遍,导致粪铜排出增加,对生态环境造成潜在威胁。文章就铜的生理功能、高铜添加效果与危害及可能的防控措施进行综述,以期为畜牧养殖过程中铜的合理应用及环境污染控制提供参考意义。
With the ban or reduction of antibiotics in animal husbandry in China, the bacteriostatic and bactericidal effects of high copper in animal intestine are enlarged. At present, the phenomenon of high-dose copper addition is widespread,which leads to the increase of copper excretion from feces and poses a potential threat to the ecological environment.Therefore, the physiological function of copper, the effect and harm of high copper addition and the possible prevention and control measures were reviewed in this paper in order to provide reference for the rational application of copper in animal husbandry and environmental pollution control.
With the ban or reduction of antibiotics in animal husbandry in China, the bacteriostatic and bactericidal effects of high copper in animal intestine are enlarged. At present, the phenomenon of high-dose copper addition is widespread,which leads to the increase of copper excretion from feces and poses a potential threat to the ecological environment.Therefore, the physiological function of copper, the effect and harm of high copper addition and the possible prevention and control measures were reviewed in this paper in order to provide reference for the rational application of copper in animal husbandry and environmental pollution control.
引文
[1]呙于明.尚未任何单一一种饲料添加剂可替代饲用抗生素[J].北方牧业,2018(15):15-16.
[2]杨凤主编.动物营养学[M].第二版.北京:中国农业出版社,2014.
[3]Braude R.Copper as a stimulant in pig feeding(cuprum pro pecunia)[J].World Rev.Anim.Prod.,1973,3:69-81.
[4]Roof M D,Mahan D C.Effect of carbadox and various dietary copper levels for weanling swine[J].J.Anim.Sci.,1982,55:1109-1117.
[5]陈学风,乌力吉.高铜饲料导致猪胃穿孔病例的诊治报告[J].猪业科学,2006(5):57-58.
[6]张政军,罗绪刚.高铜使用中的几个误区与解决方法[J].饲料研究,2006(3):61-62.
[7]Kemp P F,Aller J Y.Bacterial diversity in aquatic and other environments:What 16S R DNA libraries can tell us[J].Fems Microbiology Ecology,2004,47(47):161-177.
[8]Knop M,Dang T Q,Jeschke G.Copper is a cofactor of the formylglycine generating enzyme[J].Chembiochem.,2017,18(2):161-165.
[9]张素华,王加启.有机铜在反刍动物营养中的应用研究[J].饲料工业,2002,23(8):17-19.
[10]杜娟,高荣琨.高铜的生理功能及其影响[J].当代畜禽养殖业,2006(1):42-45.
[11]王艳花.纳米铜和硫酸铜对断奶仔猪生长、腹泻和消化的影响及作用机理探讨[D].杭州:浙江大学,2002.
[12]Gao C,Zhu L,Zhu F,et al.Effects of different sources of copper on Ctrl,ATP7A,ATP7B,MT and DMT1 protein and gene expression in Caco-2 cell[J].J.Trace Elem.Med.Biol.,2014,28:344-350.
[13]宋明明,高晨,朱凤华,等.不同铜源对鸡嗉囊Ctr1、Ctr2基因和蛋白表达的影响[J].饲料研究,2015(17):51-57.
[14]张艳玲,朱凤华,陈甫,等.不同铜源化合物在水溶液或细胞培养液中铜离子价态研究[J].中国畜牧杂志,2018,54(9):100-104.
[15]潘娜,朱连勤,朱凤华,等.雏鸡离体空肠对纳米氧化铜吸收速率的研究[J].微量元素与健康研究,2011,28(3):1-3.
[16]汪水平,王文娟,谭支良,等.影响反刍动物硒、铜生物利用率的因素[J].饲料工业,2004,25(11):30-32.
[17]徐稳,王恬.不同微量元素对猪生长性能影响的研究进展[J].家畜生态学报,2010,31(2):95-98.
[18]Buntain D.Deaths in pigs on high copper diet[J].Veterinary Record,1961,63:707-713.
[19]Grcech B L,Spear J W,Flowers W L,et al.Effect ofdietary trace mineral concentration and source(inorganic vs.chelated)on performance,mineral status and fecal mineral excretion in pigs from weaning through finishing[J].Animal Sci.,2004,82:2140-2147.
[20]李家奎,郑鑫,杨连玉,等.不同形态的铜对猪生长性能及血清GH、血浆NPY水平的影响[J].中国兽医学报,2004,24(5):488-489.
[21]邹曜宇.高铜饲料的危害及防止措施[J].现代农业科技,2010(3):343-344.
[22]Buntain D.Deaths in pigs on a high copper diet[J].Veterinary Record,1961,63:707-713.
[23]张湘琪,铜来源和水平对肉鸡生产性能、脚胫着色和组织铜沉积的影响[D].雅安:四川农业大学,2009.
[24]高凤仙.饲料中铜对猪-玉米的生理影响及其系统生态效应[D].长沙:湖南农业大学,2007.
[25]孙素玲,周如太.铜水平对断奶仔猪生长和日粮脂肪利用的影响[J].中国畜牧杂志,1996,32(1):33-34.
[26]Creech B L,Spears J W,Flowers W L,et al.Effect of dietary trace mineral concentration and source(inorganic vs.chelated)on performance,mineral status,and fecal mineral excretion in pigs from weaning through finishing[J].Journal of Animal Science,2004,82(7):2140.
[27]张喜春,池连武,高明.高锌高铜日粮对断奶仔猪生产性能的影响[J].沈阳农业大学学报,2001,32(5):399-400.
[28]彭赟.一起高铜饲料引起猪中毒病例[J].江西畜牧兽医杂志,2001(6):47.
[29]高阳,周业勋,张继泽,等.高剂量铜、锌在猪饲粮中的应用、潜在危害及解决策略[J].动物营养学报,2018(7):2459-2466.
[30]计徐,郑卫江,邹雪婷,等.饲料高铜对断奶仔猪大肠杆菌恩诺沙星耐药协同作用的研究[C]//中国猪业科技大会暨中国畜牧兽医学会2015年学术年会,2015:114.
[31]吕敏芝,黄得纯,苏佛岳,等.高剂量铜对肉鸭的作用效果[J].中国家禽,2001,23(4):10-12.
[32]杨帆.饲料的危害及防止措施[D].雅安:四川农业大学,2007.
[33]邹曜宇.高铜饲料的危害及防止措施[J].现代农业科技,2010(3):343-344.
[34]Solain S G,Shoemaker C E,Dandrea G H.The effect of high dietary Cu on health,growth performance and Cu status in young goats[J].Small Rumainant Research,2006,66(1/3):85-91.
[35]乔伟,王之盛,宾石玉.高铜在养猪生产中应用的利与弊[J].当代畜牧,2004(1):37-39.
[36]李光辉,王珏.微量元素在土壤、饲料与畜体中的含量[J].饲料研究,1995,2000(1):113-114.
[37]钱莘莘.高铜在组织中残留及排泄规律的研究[J].中国畜牧杂志,1998,34(3):36-37.
[38]徐运杰,方热军,范志勇.饲料中用高铜真能带来财源吗?[J].中国动物保健,2007(11):109-111.
[39]孙安权,曹冬梅.畜牧生产中一项节省50%微量元素技术的研究进展[C]//中国畜牧兽医学会动物营养学分会中国饲料营养学术研讨会.2014.
[40]敖子强,熊继海,王顺发,等.畜禽养殖废弃物重金属铜的污染治理及循环利用[J].广东农业科学,2011,38(17):127-129.
[41]左建武,韩瑞华,王春燕,等.铜川地区畜禽养殖业污染现状及综合治理[J].畜禽业,2008(10):53-34.
[42]王传花,崔灵周,王栋.乐清湾养殖区表层沉积物重金属含量分布及污染评价[J].农业工程学报,2015,31(2):204-210.
[43]杜卫莉.我国南方养猪业污染现状监测分析[J].广东化工,2016,43(3):86-88,83.
[44]Abreu M F D,Berton R S,Andrade J C D.Comparison of methods to evaluate heavy metals in organic wastes[J].Communications in Soil Science&Plant Analysis,1996,27(5/8):1125-1135.
[45]Eneji A E,Yamamoto S,Honna T,et al.Physico-chemical changes in livestock feces during composting[J].Communications in Soil Science&Plant Analysis,2001,32(3/4):477-489.
[46]刘荣乐,李书天,王秀斌,等.我国商品有机肥料和有机废弃物中重金属的含量状况与分析[J].农业环境科学学报,2005,24(2):392-397.
[47]邢文英.中国肥料使用中存在的主要问题及对策[C]//中国土壤学会海峡两岸土壤肥料学术研讨会.
[48]宋景萍.铜对产蛋鸡生产性能及蛋壳品质的影响[J].黑龙江畜牧兽医,2017(14):193-194.
[49]赵颖彩.日粮铜源及其水平对猪中枢内多巴胺代谢的影响[D].长春:吉林农业大学,2005.
[50]王丹,唐金虎.饲料中高铜带来的危害及防控措施[J].中国饲料添加剂,2008(10):9-12.
[51]何万领,李晓丽,张金汉,等.微生物发酵铁、锌、锰、铜对蛋鸡生产性能和血清指标的影响[J].中国兽医学报,2018(2):398-403.
[52]窦勇,彭聚华,胡佩红,等.低氮低磷日粮添加植酸酶对仔猪钙、磷及微量元素矿物元素代谢的影响[J].饲料研究,2015(8):29-31.
[53]董国忠,张翥,王小晶,等.饲粮中添加植酸酶对生长肥育猪矿物元素利用和排泄的影响[J].中国饲料,2007(12):8-11.
[54]张艺伟,余晓楠,蒋翰霆,等.基于体外消化模拟酶制剂处理对饲料原料微量元素释放效率研究[J].中国畜牧杂志,2016,52(11):43-48.
[55]郝明德,魏孝荣,党廷辉.旱地小麦长期施用锌肥的增产作用和土壤效应[J].植物营养与肥料学报,2003,9(3):377-380.
[56]He W L,Shohag M J I,Wei Y Y,et al.Iron concentration,bioavailability and nutritional quality of polished rice affected by different forms of foliar iron fertilizer[J].Food Chemistry,2013,141:4122-4126.
[56]Anon.Regional poverty targeting in china-sciencedirect[J].s.n..
[57]丁文军,王郁文.植酸与微量元素[J].国外医学(地理分册),2001,22(2):58-60.
[58]Clara I F,Angeles A.Phytic acid level in edible grain derivatives in the canary islands(gofio and frangollo)[J].Europe Food Research Technology,2000,210:346-348.
[2]杨凤主编.动物营养学[M].第二版.北京:中国农业出版社,2014.
[3]Braude R.Copper as a stimulant in pig feeding(cuprum pro pecunia)[J].World Rev.Anim.Prod.,1973,3:69-81.
[4]Roof M D,Mahan D C.Effect of carbadox and various dietary copper levels for weanling swine[J].J.Anim.Sci.,1982,55:1109-1117.
[5]陈学风,乌力吉.高铜饲料导致猪胃穿孔病例的诊治报告[J].猪业科学,2006(5):57-58.
[6]张政军,罗绪刚.高铜使用中的几个误区与解决方法[J].饲料研究,2006(3):61-62.
[7]Kemp P F,Aller J Y.Bacterial diversity in aquatic and other environments:What 16S R DNA libraries can tell us[J].Fems Microbiology Ecology,2004,47(47):161-177.
[8]Knop M,Dang T Q,Jeschke G.Copper is a cofactor of the formylglycine generating enzyme[J].Chembiochem.,2017,18(2):161-165.
[9]张素华,王加启.有机铜在反刍动物营养中的应用研究[J].饲料工业,2002,23(8):17-19.
[10]杜娟,高荣琨.高铜的生理功能及其影响[J].当代畜禽养殖业,2006(1):42-45.
[11]王艳花.纳米铜和硫酸铜对断奶仔猪生长、腹泻和消化的影响及作用机理探讨[D].杭州:浙江大学,2002.
[12]Gao C,Zhu L,Zhu F,et al.Effects of different sources of copper on Ctrl,ATP7A,ATP7B,MT and DMT1 protein and gene expression in Caco-2 cell[J].J.Trace Elem.Med.Biol.,2014,28:344-350.
[13]宋明明,高晨,朱凤华,等.不同铜源对鸡嗉囊Ctr1、Ctr2基因和蛋白表达的影响[J].饲料研究,2015(17):51-57.
[14]张艳玲,朱凤华,陈甫,等.不同铜源化合物在水溶液或细胞培养液中铜离子价态研究[J].中国畜牧杂志,2018,54(9):100-104.
[15]潘娜,朱连勤,朱凤华,等.雏鸡离体空肠对纳米氧化铜吸收速率的研究[J].微量元素与健康研究,2011,28(3):1-3.
[16]汪水平,王文娟,谭支良,等.影响反刍动物硒、铜生物利用率的因素[J].饲料工业,2004,25(11):30-32.
[17]徐稳,王恬.不同微量元素对猪生长性能影响的研究进展[J].家畜生态学报,2010,31(2):95-98.
[18]Buntain D.Deaths in pigs on high copper diet[J].Veterinary Record,1961,63:707-713.
[19]Grcech B L,Spear J W,Flowers W L,et al.Effect ofdietary trace mineral concentration and source(inorganic vs.chelated)on performance,mineral status and fecal mineral excretion in pigs from weaning through finishing[J].Animal Sci.,2004,82:2140-2147.
[20]李家奎,郑鑫,杨连玉,等.不同形态的铜对猪生长性能及血清GH、血浆NPY水平的影响[J].中国兽医学报,2004,24(5):488-489.
[21]邹曜宇.高铜饲料的危害及防止措施[J].现代农业科技,2010(3):343-344.
[22]Buntain D.Deaths in pigs on a high copper diet[J].Veterinary Record,1961,63:707-713.
[23]张湘琪,铜来源和水平对肉鸡生产性能、脚胫着色和组织铜沉积的影响[D].雅安:四川农业大学,2009.
[24]高凤仙.饲料中铜对猪-玉米的生理影响及其系统生态效应[D].长沙:湖南农业大学,2007.
[25]孙素玲,周如太.铜水平对断奶仔猪生长和日粮脂肪利用的影响[J].中国畜牧杂志,1996,32(1):33-34.
[26]Creech B L,Spears J W,Flowers W L,et al.Effect of dietary trace mineral concentration and source(inorganic vs.chelated)on performance,mineral status,and fecal mineral excretion in pigs from weaning through finishing[J].Journal of Animal Science,2004,82(7):2140.
[27]张喜春,池连武,高明.高锌高铜日粮对断奶仔猪生产性能的影响[J].沈阳农业大学学报,2001,32(5):399-400.
[28]彭赟.一起高铜饲料引起猪中毒病例[J].江西畜牧兽医杂志,2001(6):47.
[29]高阳,周业勋,张继泽,等.高剂量铜、锌在猪饲粮中的应用、潜在危害及解决策略[J].动物营养学报,2018(7):2459-2466.
[30]计徐,郑卫江,邹雪婷,等.饲料高铜对断奶仔猪大肠杆菌恩诺沙星耐药协同作用的研究[C]//中国猪业科技大会暨中国畜牧兽医学会2015年学术年会,2015:114.
[31]吕敏芝,黄得纯,苏佛岳,等.高剂量铜对肉鸭的作用效果[J].中国家禽,2001,23(4):10-12.
[32]杨帆.饲料的危害及防止措施[D].雅安:四川农业大学,2007.
[33]邹曜宇.高铜饲料的危害及防止措施[J].现代农业科技,2010(3):343-344.
[34]Solain S G,Shoemaker C E,Dandrea G H.The effect of high dietary Cu on health,growth performance and Cu status in young goats[J].Small Rumainant Research,2006,66(1/3):85-91.
[35]乔伟,王之盛,宾石玉.高铜在养猪生产中应用的利与弊[J].当代畜牧,2004(1):37-39.
[36]李光辉,王珏.微量元素在土壤、饲料与畜体中的含量[J].饲料研究,1995,2000(1):113-114.
[37]钱莘莘.高铜在组织中残留及排泄规律的研究[J].中国畜牧杂志,1998,34(3):36-37.
[38]徐运杰,方热军,范志勇.饲料中用高铜真能带来财源吗?[J].中国动物保健,2007(11):109-111.
[39]孙安权,曹冬梅.畜牧生产中一项节省50%微量元素技术的研究进展[C]//中国畜牧兽医学会动物营养学分会中国饲料营养学术研讨会.2014.
[40]敖子强,熊继海,王顺发,等.畜禽养殖废弃物重金属铜的污染治理及循环利用[J].广东农业科学,2011,38(17):127-129.
[41]左建武,韩瑞华,王春燕,等.铜川地区畜禽养殖业污染现状及综合治理[J].畜禽业,2008(10):53-34.
[42]王传花,崔灵周,王栋.乐清湾养殖区表层沉积物重金属含量分布及污染评价[J].农业工程学报,2015,31(2):204-210.
[43]杜卫莉.我国南方养猪业污染现状监测分析[J].广东化工,2016,43(3):86-88,83.
[44]Abreu M F D,Berton R S,Andrade J C D.Comparison of methods to evaluate heavy metals in organic wastes[J].Communications in Soil Science&Plant Analysis,1996,27(5/8):1125-1135.
[45]Eneji A E,Yamamoto S,Honna T,et al.Physico-chemical changes in livestock feces during composting[J].Communications in Soil Science&Plant Analysis,2001,32(3/4):477-489.
[46]刘荣乐,李书天,王秀斌,等.我国商品有机肥料和有机废弃物中重金属的含量状况与分析[J].农业环境科学学报,2005,24(2):392-397.
[47]邢文英.中国肥料使用中存在的主要问题及对策[C]//中国土壤学会海峡两岸土壤肥料学术研讨会.
[48]宋景萍.铜对产蛋鸡生产性能及蛋壳品质的影响[J].黑龙江畜牧兽医,2017(14):193-194.
[49]赵颖彩.日粮铜源及其水平对猪中枢内多巴胺代谢的影响[D].长春:吉林农业大学,2005.
[50]王丹,唐金虎.饲料中高铜带来的危害及防控措施[J].中国饲料添加剂,2008(10):9-12.
[51]何万领,李晓丽,张金汉,等.微生物发酵铁、锌、锰、铜对蛋鸡生产性能和血清指标的影响[J].中国兽医学报,2018(2):398-403.
[52]窦勇,彭聚华,胡佩红,等.低氮低磷日粮添加植酸酶对仔猪钙、磷及微量元素矿物元素代谢的影响[J].饲料研究,2015(8):29-31.
[53]董国忠,张翥,王小晶,等.饲粮中添加植酸酶对生长肥育猪矿物元素利用和排泄的影响[J].中国饲料,2007(12):8-11.
[54]张艺伟,余晓楠,蒋翰霆,等.基于体外消化模拟酶制剂处理对饲料原料微量元素释放效率研究[J].中国畜牧杂志,2016,52(11):43-48.
[55]郝明德,魏孝荣,党廷辉.旱地小麦长期施用锌肥的增产作用和土壤效应[J].植物营养与肥料学报,2003,9(3):377-380.
[56]He W L,Shohag M J I,Wei Y Y,et al.Iron concentration,bioavailability and nutritional quality of polished rice affected by different forms of foliar iron fertilizer[J].Food Chemistry,2013,141:4122-4126.
[56]Anon.Regional poverty targeting in china-sciencedirect[J].s.n..
[57]丁文军,王郁文.植酸与微量元素[J].国外医学(地理分册),2001,22(2):58-60.
[58]Clara I F,Angeles A.Phytic acid level in edible grain derivatives in the canary islands(gofio and frangollo)[J].Europe Food Research Technology,2000,210:346-348.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |