羊肚菌胞内多糖对小鼠运动心肌损伤的影响
|
摘要
探究羊肚菌胞内多糖对小鼠运动心肌损伤的影响。选择100只患有运动心肌损伤的小鼠作为研究对象,将其划分为A组和B组,对A组投喂安慰剂,对B组投喂多糖肠溶胶丸,在羊肚菌胞内多糖浓度为20%、40%、80%的情况下观察小鼠心肌损伤恢复蛋白T浓度与心肌损伤恢复率的变化。结果表明:当羊肚菌胞内多糖浓度为20%时,B组小鼠心肌损伤恢复率为23.26%;当羊肚菌胞内多糖浓度为40%时,B组小鼠心肌损伤恢复率为45.21%;当羊肚菌胞内多糖浓度为80%时,B组小鼠心肌损伤恢复率为68. 94%。随着投喂羊肚菌胞内多糖胶囊浓度的增加,B组小鼠心肌损伤恢复率越来越大,对小鼠运动心肌损伤恢复的促进作用也随之增大。
To investigate the effects of intracellular polysaccharides of Morchella esculenta on myocardial injury induced by exercise in mice. 100 mice with exercise-induced myocardial injury were divided into group A and group B. Placebo was given to group A and polysaccharide enteric-coated pills were given to group B. The changes of myocardial injury recovery protein T concentration and myocardial injury recovery rate were observed when the intracellular polysaccharide concentration of M. esculenta was 20%, 40% and 80%. When the concentration of intracellular polysaccharide of M. esculenta was 20%, the recovery rate of myocardial injury in group B was 23.26%, when the concentration of intracellular polysaccharide of M. esculenta was 40%, the recovery rate of myocardial injury in group B was 45.21%; when the concentration of intracellular polysaccharide of M. esculenta was 80%, the recovery rate of myocardial injury in group B was 68. 94%. With the increase of intracellular polysaccharide capsule concentration of M. esculenta, the recovery rate of myocardial injury in group B mice is getting higher and higher, and the promoting effect on the recovery of exercise myocardial injury in mice is also increasing.
To investigate the effects of intracellular polysaccharides of Morchella esculenta on myocardial injury induced by exercise in mice. 100 mice with exercise-induced myocardial injury were divided into group A and group B. Placebo was given to group A and polysaccharide enteric-coated pills were given to group B. The changes of myocardial injury recovery protein T concentration and myocardial injury recovery rate were observed when the intracellular polysaccharide concentration of M. esculenta was 20%, 40% and 80%. When the concentration of intracellular polysaccharide of M. esculenta was 20%, the recovery rate of myocardial injury in group B was 23.26%, when the concentration of intracellular polysaccharide of M. esculenta was 40%, the recovery rate of myocardial injury in group B was 45.21%; when the concentration of intracellular polysaccharide of M. esculenta was 80%, the recovery rate of myocardial injury in group B was 68. 94%. With the increase of intracellular polysaccharide capsule concentration of M. esculenta, the recovery rate of myocardial injury in group B mice is getting higher and higher, and the promoting effect on the recovery of exercise myocardial injury in mice is also increasing.
引文
[1]江洁，王艳，李佳桐.羊肚菌菌丝体锌多糖的体内、体外抗氧化作用[J].食品科学，2018,39（13）：12-16.
[2]刘景辉.羊肚菌的药用价值研究[J].农业开发与装备，2013（12):96-97.
[3]黄瑶，蒋琳，刘影.羊肚菌多糖提取、分离纯化及免疫调节活性[J].生物加工过程，2018,16(6):39-45.
[4]李美华，孙玉侠，曾阳，等.粗柄羊肚菌菌丝体多糖及胞外多糖的提取工艺[J].菌物研究，2017,15(3):195-200.
[5]顾可飞，刘海燕，杨海峰，等.电子束辐照对羊肚菌营养成分影响分析[J].食品工业科技，2018,39(12):45-46.
[6]郝文忠，储庆，张囡囡，等.响应面法优化羊肚菌多糖-葡萄糖胺共聚物的制备工艺[J].安徽科技学院学报，2017,31(4):71-77.
[7]顾可飞，周昌艳，邵毅，等.云南省野生牛肝菌与羊肚菌营养成分分析[J].食品研究与开发，2017,38(17):129-133.
[8]何淑玲，赵垦田，马令法，等.不同栽培种配方对羊肚菌生长及品质的影响[J].食用菌，2017,39(4):27-30.
[9]王道周，裘志成，杨艳，等.姜黄素对2型糖尿病肾病大鼠保护作用及机制研究[J].中国免疫学杂志，2017,33(4）：588-592.
[10]徐繁，李潇，刘兰芳，等.灵芝多糖对阿霉素致心肌损伤保护作用的研究[J].中国地方病防治杂志，2017,7(4):372-375.
[11]刘莹莹，武俊紫，李伟，等.金钗石斛多糖对Ⅱ型糖尿病大鼠心肌组织中MMP-1和MMP-9表达的影响[J].西部医学，2017,23(10):1346-1351.
[12]赵晓航，邱晓梅，王斌.黄芪多糖对大鼠心肌缺血再灌注损伤的影响[J].中国老年学杂志，2018,38(18):4492-4494.
[13]钟林，詹剑华，罗锦花.黄芪多糖对严重烫伤兔心功能损害的作用[J].中华烧伤杂志，2017,33(11):668.
[14]袁雨培，张鑫，宋鹏，等.积雪草酸对脂多糖所致H9C2心肌细胞损伤的改善作用[J].广西医学，2018,40(1):61-64.
[2]刘景辉.羊肚菌的药用价值研究[J].农业开发与装备，2013（12):96-97.
[3]黄瑶，蒋琳，刘影.羊肚菌多糖提取、分离纯化及免疫调节活性[J].生物加工过程，2018,16(6):39-45.
[4]李美华，孙玉侠，曾阳，等.粗柄羊肚菌菌丝体多糖及胞外多糖的提取工艺[J].菌物研究，2017,15(3):195-200.
[5]顾可飞，刘海燕，杨海峰，等.电子束辐照对羊肚菌营养成分影响分析[J].食品工业科技，2018,39(12):45-46.
[6]郝文忠，储庆，张囡囡，等.响应面法优化羊肚菌多糖-葡萄糖胺共聚物的制备工艺[J].安徽科技学院学报，2017,31(4):71-77.
[7]顾可飞，周昌艳，邵毅，等.云南省野生牛肝菌与羊肚菌营养成分分析[J].食品研究与开发，2017,38(17):129-133.
[8]何淑玲，赵垦田，马令法，等.不同栽培种配方对羊肚菌生长及品质的影响[J].食用菌，2017,39(4):27-30.
[9]王道周，裘志成，杨艳，等.姜黄素对2型糖尿病肾病大鼠保护作用及机制研究[J].中国免疫学杂志，2017,33(4）：588-592.
[10]徐繁，李潇，刘兰芳，等.灵芝多糖对阿霉素致心肌损伤保护作用的研究[J].中国地方病防治杂志，2017,7(4):372-375.
[11]刘莹莹，武俊紫，李伟，等.金钗石斛多糖对Ⅱ型糖尿病大鼠心肌组织中MMP-1和MMP-9表达的影响[J].西部医学，2017,23(10):1346-1351.
[12]赵晓航，邱晓梅，王斌.黄芪多糖对大鼠心肌缺血再灌注损伤的影响[J].中国老年学杂志，2018,38(18):4492-4494.
[13]钟林，詹剑华，罗锦花.黄芪多糖对严重烫伤兔心功能损害的作用[J].中华烧伤杂志，2017,33(11):668.
[14]袁雨培，张鑫，宋鹏，等.积雪草酸对脂多糖所致H9C2心肌细胞损伤的改善作用[J].广西医学，2018,40(1):61-64.