小儿单纯性与复杂性热性惊厥临床特点及脑电图分析
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摘要
目的分析不同性质小儿热性惊厥(FC)患儿的临床特点及脑电图表现。方法选取2016年1月~2018年5月期间我院儿科住院部收治的81例小儿热性惊厥者作为观察对象,并根据基本性质不同分为单纯性FC(SFC)组(43例),以及复杂性FC(CFC)组(38例),所有患儿行脑电图检查,比较SFC、CFC患儿惊厥发作时临床特点,同时观察两组患儿脑电图情况。结果 CFC组较SFC组患儿发作时体温低、发作次数多、持续时间长,P <0.05;CFC组异常脑电、临界脑电为26.3%、34.2%高于SFC组11.6%、20.9%,P <0.05。结论小儿FC患者发作时会造成不同程度的脑损伤,其中SFC者脑电图异常率较低,脑损伤轻微,而CFC患儿脑电图异常率高,脑损伤较严重,临床需要及时积极给予神经功能保护、预防治疗。
Objective To analyze the characteristics and electroencephalogram analysis of simple and complex febrile convulsion(FC) in children. Methods 81 children with febrile convulsion who were admitted and treated in pediatric inpatient department in our hospital from January 2016 to May 2018 were selected as research objects.According to different basic properties,they were divided into simple FC(SFC) group and complex FC(CFC) group,with38 cases in each group.All children were examined by electroencephalogram(EEG).The clinical characteristics of convulsion in SFC and CFC children were compared,and the EEG results of the two groups were observed. Results Compared with children in the SFC group, children in the CFC group had lower body temperature,more seizures and longer duration,P < 0.05.The abnormal EEG and critical EEG in the CFC group were 26.3% and 34.2% higher than those in the SFC group(11.6%,20.9%),P < 0.05. Conclusion Children with FC can cause different degrees of brain damage during seizures.Among them,SFC patients have lower EEG abnormalities and mild brain damage,but the abnormal rate of EEG in children with CFC is high and brain damage is serious.Clinically,it is necessary to give active protection and preventive treatment to neurological function in time.
Objective To analyze the characteristics and electroencephalogram analysis of simple and complex febrile convulsion(FC) in children. Methods 81 children with febrile convulsion who were admitted and treated in pediatric inpatient department in our hospital from January 2016 to May 2018 were selected as research objects.According to different basic properties,they were divided into simple FC(SFC) group and complex FC(CFC) group,with38 cases in each group.All children were examined by electroencephalogram(EEG).The clinical characteristics of convulsion in SFC and CFC children were compared,and the EEG results of the two groups were observed. Results Compared with children in the SFC group, children in the CFC group had lower body temperature,more seizures and longer duration,P < 0.05.The abnormal EEG and critical EEG in the CFC group were 26.3% and 34.2% higher than those in the SFC group(11.6%,20.9%),P < 0.05. Conclusion Children with FC can cause different degrees of brain damage during seizures.Among them,SFC patients have lower EEG abnormalities and mild brain damage,but the abnormal rate of EEG in children with CFC is high and brain damage is serious.Clinically,it is necessary to give active protection and preventive treatment to neurological function in time.
引文
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[3]李晓军,李晓岚.动态脑电图联合神经元特异性烯醇化酶检测在婴幼儿热性惊厥中的应用[J].山西医科大学学报,2016,47(1):83-86.
[4]冯鑫飞,唐云芳,王钟瑾.复杂型热性惊厥临床和脑电图特征与日后癫痫发生关系的研究[J].中国现代医生,2014,52(13):19-21,24.
[5]孙文秀,王学禹.实用小儿神经系统疾病诊断与治疗[M].济南:山东科学技术出版社,2006:147-152.
[6]刘晓燕.临床脑电图学[M].北京:人民卫生出版社,2006:215-216,378-381.
[7]吴星,王艳.热性惊厥患儿血清及脑脊液肾上腺髓质素及神经元特异性烯醇化酶水平与脑损伤的关系[J].中华实用诊断与治疗杂志,2015,29(5):476-477,480.
[8]夏晓文.单纯性热性惊厥与复杂性热性惊厥的临床特征对比研究[J].中国妇幼保健,2015,30(25):4317-4319.
[9]王增成.小儿热性惊厥临床特点及脑电图分析[J].中国现代药物应用,2015,9(24):41-42.
[10]刘芬,高玉娜,王丽丽.326例高热惊厥脑电图及临床分析[J].中国实用神经疾病杂志,2014,17(13):92.
[11]温清芬,王芳,林亚芬,等.298例小儿首次热性惊厥发作的临床特征及其影响因素分析[J].中国妇幼保健,2017,32(9):1933-1936.
[12]黄丽.小儿热性惊厥脑电图特征异常与后期癫痫发作的相关性[J].医学理论与实践,2017,30(15):2291-2292.
[13]Ebrahim Rajab,Zahra Abdeen,Zuhair Hassan et al.Cognitive performance and convulsion risk after experimentally-induced febrile-seizures in rat[J].International Journal of Developmental Neuroscience:the Official Journal of the International Society for Developmental Neuroscience,2014,34:19-23.
[14]陈旭艳.儿童热性惊厥脑电图与临床关系分析[J].中国实用神经疾病杂志,2012,15(4):37-38.
[15]张珍端,申艳平.小儿热性惊厥85例脑电图分析[J].中国医药导刊,2012,14(11):1849,1851.
[16]弓高云,刘芬,李金荣.动态脑电图联合NSE检测对复杂性与单纯性热性惊厥患儿的鉴别诊断价值[J].安徽医学,2018,39(4):453-455.
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