用户名: 密码: 验证码:
车辆碰撞事故中头部生物力学响应和损伤机理分析
详细信息    本馆镜像全文|  推荐本文 |  |   获取CNKI官网全文
摘要
头部损伤是汽车交通事故中最为常见的伤害类型之一,而且头部损伤是造成重伤或者死亡的主要致伤形式。由于头部创伤导致的治疗、赔偿和死亡带来了大量的社会和经济问题。以英国为例,1997年大约40%的头部损伤是由于交通事故导致的。在我国,随着经济发展和国内汽车市场的升温,汽车保有量急剧增加,我国的道路交通事故发生率一直居高不下,而其中头部损伤在交通伤害中占了较高的比例(约为22.5~41%)。因此,在我国开展针对头部损伤的形式、损伤机理、耐受限度和防护方法的研究具有重要的现实意义。本文主要进行基于真实人体解剖学结构的头部建模和验证工作;将开发的头部有限元模型用于典型行人碰撞事故重建和损伤分析研究工作;并提出相关降低头部损伤的防护措施。
     人体头部具有极为复杂的解剖学结构,同时包含了人体中枢神经系统最重要的器官,对头部进行研究的手段受到极大的限制。在过去的几十年中,研究人员在头部损伤机理的研究领域提出了很多种假说,但是真正意义上能够完整揭示致伤机制的理论仍然有待完善。本文在前人研究的基础上,对头部载荷条件、损伤机理等研究成果进行了总结,同时对有限元方法在人体头部损伤研究领域的应用进行了回顾。以显式有限元分析软件LS-DYNA和多刚体动力学分析软件MADYMO为主要的研究工具,进行了头部损伤研究工作。建立了基于真实人体解剖学结构的三维头部有限元模型,这一有限元模型被命名为人体头部模型(Human Body Model-head,HBM-head)。模型描述了主要的颅脑解剖学结构,包括头皮、颅骨、硬脑膜、脑脊液、软脑膜、大脑、小脑、脑室、脑干、脑镰和脑幕等等。整个模型由66 624个节点,49 607个实体单元和11 514个壳单元组成,头部模型质量为4.4 kg。脑组织的材料特性来自于国内外文献资料。
     基于国外不同时期经典的尸体实验的数据对HBM头部模型进行了验证,比较了Nahum(1976年)和Trosseille(1992年)的实验与仿真分析中的头部动力学响应参数以及颅内压力;同时再现了碰撞过程冲击-对冲伤害模式的压力梯度分布情况,并计算了颅内应力应变分布。另外,通过Hardy实验验证分析了模型模拟颅脑相对运动的能力。同时根据国外颅骨冲击实验数据,对头部骨折的力学特性进行了验证分析。结果表明,仿真分析与实验的结果吻合较好,模型具有较高的生物逼真度,可以用于颅脑损伤的颅内应力应变分布、颅内压力等相关参数研究,以及头部骨折伤害研究。
     汽车碰撞事故中,行人、骑自行车人等易受伤害的道路使用者非常容易受到严重和致命伤害,而且头部损伤在这类事故中占了相当高的比例。本文基于德国汉诺威医科大学提供的行人交通事故的数据,使用多刚体动力学人体模型和HBM头部模型进行了三例典型事故的分析和重建工作。建立并完善了由道路交通事故调查数据—事故重建—损伤分析的研究方法,准确的重现了事故中人体的动力学响应过程;同时根据事故损伤分析得到的各种损伤评估指标,与事故中受害者的伤情报告进行对比。结果表明,模型具有一定的损伤预测能力,计算得到的各种损伤评价指标对于损伤类型和严重程度具有较好的对比性。
     由于行人—风挡玻璃碰撞是行人安全中的一个研究热点,本文基于事故案例进行了头部—风挡玻璃碰撞的骨折损伤研究。在建立事故对应的车体模型的基础上,通过模拟事故中行人头部与车体前风挡玻璃等相关结构的碰撞过程,得到不同条件下人体头部颅骨的受力情况和骨折损伤情况,分析结果与事故中的伤情报告具有很好的一致性。
     通过采用HBM头部模型和行人头锤模型对汽车风挡玻璃不同区域进行碰撞分析,给出相应的损伤风险分布趋势图;在此基础上,提出双L型气囊的防护结构及设计尺寸;通过多刚体动力学仿真分析,研究了这一气囊在行人碰撞中的防护能力。结果表明,L型气囊能够显著降低行人—风挡玻璃碰撞中车体对行人头部的碰撞强度,降低头部骨折伤害的风险;同时能够对人体头颈部和肩部起到缓冲的作用效果,降低头部由于旋转运动造成的伤害,因此该气囊对头部损伤具有良好的防护效果。
     中国汽车行业发展迅速,道路交通事故和头部交通伤的防治工作日益成为值得关注的焦点问题。本研究通过建立人体头部模型,开展事故重建和损伤分析工作,了解交通伤作用机理并据此开展防护措施的研究,对我国汽车安全行业的发展和交通伤防治具有重大的现实意义。
Head injuries are often sustained in traffic accidents and head traumas are most likely to result in severe injury and death. Medical treatment, compensation, and deaths related to head injuries lead to significant social costs. In 1997, approximately 40 percent of head injuries occurred in traffic accident in U.K. In China, economic development and rapid increases in the number of vehicles have resulted in an increased accident rate, with head injuries making up a significant proportion of injuries suffered in traffic accidents (about 22.5~41%). Therefore, it is vital to conduct research about types of head injuries, injury mechanisms, injury tolerance, and protective measures in China. This study focused on the modeling and validation of a finite element head model based on real human anatomical structures; the resulting model was subsequently used in the reconstruction of a typical pedestrian accident and the analysis of head injury. Finally, a protective measure for head injury was suggested.
     The human head has an extremely complex structure that includes the most vital organ of the central nervous system, yet methods for studying the human head and brain are quite limited. During the past several decades, many hypotheses have been presented, but an entire systemic theory to explain the head injury mechanism remains lacking. The current work first reviewed previous studies of head mechanical loads and injury mechanisms as well as the application of the finite element method. A study of head injury using software based on the explicit finite element method and multi-body dynamics method was then carried out, ultimately developing a new 3D finite element head model based on the anatomical structure of a real human body. This model was named the Human Body Model-head (or HBM-head). The main structures of the head include the scalp, skull, dura, cerebral spinal fluid, pia mater, cerebrum, cerebellum, brain stem, falx, and tentorium. The entire model consisted of 66,624 nodes, 49,607 solid elements, and 11,514 shell elements and weighed 4.4 kilograms. The material properties of the brain tissue were defined based on the literature.
     Various classical cadaver experiments were simulated to validate the HBM-head model. The head dynamical parameters and intracranial pressures of simulation were compared with the test results of Nahum (1976) and Trosseille (1992). The pressure gradient distribution of coup and contercoup injury was presented, and the intracranial stress and strain were calculated. In addition, using the Hardy test, the capability of simulating the skull-brain relative motion was validated with the setting. The mechanical properties of skull fracture were validated using foreign skull impact experiments. The results of these simulations fit well with those of previous tests, suggesting that this model has good biofidelity and can be used in the parameter study of intracranial stress and pressure of brain injury and skull fracture.
     Vulnerable road users—namely, pedestrians and bicyclers—often suffer severe and fatal injuries in car collisions. Head injuries are a high proportion of such traffic accidents. In this study, three typical pedestrian accidents were analyzed and reconstructed using the multi-body pedestrian model and HBM-head FE model, incorporating data from the Accident Research Unit of the Medical University in Hanover, Germany. The method of accident investigation, reconstruction, and injury analysis was presented, discussed, and improved upon. Pedestrians’dynamic responses were reconstructed, and the injury criterion indices calculated from these reconstructions were compared with diagnosis reports, demonstrating that this model has the capability to predict injuries while the calculated injury indices indicate a good ability to predict corresponding injury types and severity.
     Moreover, pedestrian-windshield impact is a popular study topic in pedestrian safety. A study focused on skull fractures in pedestrian-windshield collisions was implemented based on accident cases. The corresponding vehicle models were established, and the head-windshield impact processes of the accidents were reconstructed. The human skull’s contact force and injury condition were simulated in various conditions. The results fit well with the diagnosis reports.
     The HBM-head model and pedestrian headform model were used to impact different areas of the car windshield. An injury risk distribution figure was presented. The design of a double-side L-shape airbag for pedestrian protection was suggested based on the results of this study, and a multi-body dynamic analysis was carried out to evaluate the protective capability of this airbag. The results indicated that this L-shape airbag can significantly reduce the head impact force in pedestrian-windshield impact as well as the injury risk of skull fractures; it also serves as a cushion to the human head, neck, and shoulders, reducing head injury related to head rotation. Thus, such an airbag is an effective protection device for head injury.
     China’s rapid development in the automotive industry means the prevention of traffic accidents and injuries involving the head are an important problem that requires more attention. The current study developed a human body head model, carried out accident reconstruction and injury analysis to understand traffic injury mechanisms, which provided background knowledge for studies of protective measurements. As such, this work has important practical meaning to the development of vehicle safety and the prevention of traffic injuries.
引文
[1] 世界卫生组织.世界预防道路交通伤害报告. 瑞士:世界卫生组织,2004,1-24
    [2] Gennarelli T, Champion H, and Copers W. Importance of mortality from head injury in immediate survivors of vehicular injuries. In: Proc of IRCOBI Conference. Verona, Italy,1992, 167-178
    [3] Lee J W, Yoon K H, Kang Y S, et al. Vehicle hood and bumper structure design to mitigate casualties of pedestrian accidents. In:Proc of 19th ESV Conference. Washington DC, 2005
    [4] EEVC. European new car assessment programme-assessment protocol and biomechanical limits. Belgium: EuroNCAP group, 2004,1-4
    [5] Ren H J, Wang W P, Ge Z M. Glasgow coma scale, brain electric activity mapping and glasgow outcome scale after hyperbaric oxygen treatment of severe brain injury. Chinese Journal of Traumatology (English version, 2001,4(4): 239-241
    [6] Gennarelli T A, Wodzin E. The abbreviated injury scale-1990 revision. USA:Association for the Advancement of Automotive Medicine,1990,13-15
    [7] Centers for Disease Control and Prevention. Traumatic brain injury -- Colorado, Missouri, Oklahoma, and Utah, 1990-1993. MMWR, 1997, 46(1):8-11
    [8] Bruns J and Hauser W. The epidemiology of traumatic brain injury: A review. Epilepsia, 2003,44(10): 2-10
    [9] Waxweiler R, Thurman D, Sniezek J, et al. Monitoring the impact of traumatic brain injury: A review and update. Journal of Neurotrauma, 1995,12(4): 509-516
    [10] EEVC. Report in motorcycle safety. Brussels: European Transport Safety Council, 1993,1-15
    [11] EEVC. A strategic road safety plan for the european union. Brussels: European Transport Safety Council, 1997,3-17
    [12] Viano D, Aldman B, Pape K, et al. Brain kinematics in physical model tests with translational and rotational acceleration. International Journal of Crashworthiness, 1997,2(2):191-205
    [13] Viano D, Holst H, Gordon E. Serious brain injury from traffic related causes: Priorities for primairy prevention. Accident Analysis & Prevention, 1997,29(6):811-816
    [14] Nakamura N, Yamaura A, Shigemori M, et al. Prevention and countermeasuresagainst severe traumatic brain injury in japan and abroad. Neurological Research, 2002, 24(1):45-53
    [15] Fearnside M R and Simpson D A. Epidemiology in national neurotrauma society guest book. USA: National Neurotrauma Society, 2004,3-23
    [16] Carsten O and Day J. Injury priority analysis, task a. USA: Department of Transportation National Highway Traffic Safety Administration (NHTSA),1988,2-30
    [17] Finkelstein M and O’Connor L. United States report. In: Proc of 12th International Technical Conference on Experimental Safty Vechicles. USA, 1989, 29-36
    [18] Viano D. Perspectives on head injury research. In: Proc of the AAAM/IRCOBI Conference on the Biomechanics of Impacts. G?oteborg, Sweden, 1985,159-176
    [19] Jorgensen N O, Koornstra M, Broughton J, et al. Exposure data for travel risk assessment: Current practice and future needs in the EU. Denmark: European Transport Safety Council, 1999
    [20] 公安部.中华人民共和国道路交通事故统计年报(2005 年度).北京:公安部交通管理局, 2006, 2-14
    [21] 李钢,史克珊,曹作为. 573 例颅脑交通伤流行病学特征.中华创伤杂志, 2000, 16(3): 188
    [22] 孔禄生,欧阳向华,彭自安. 4000 例交通事故伤流行病学特征.创伤外科杂志,2003, 5(2): 141
    [23] 徐国成,韩秋生,霍琨.人体解剖学彩色图谱. 第一版.沈阳:辽宁科学技术出版社, 2003: 150-180
    [24] Kleiven S. Finite element modeling of the human head:[dissertation]. Stochholm: Royal Institute of Technology, Sweden, 2002,2-7
    [25] Moore K and Agur A M R. Essential clinical anatomy. Philadelphia: Williams & Wilkins,1996, 1-25
    [26] Denny B D and Russell W R. Experimental cerebral concussion. Brain, 1943, 64: 93
    [27] Ommaya A K, Yarnell P, Hirsch A E, et al. Scaling of experimental data on cerebral concussion in sub-human primates to concussion threshold fro man. In: Proc of 11th Stapp Car Crash Conference. California, USA: Society of Automotive Engineers, 1967,73-80
    [28] Ommaya A K, Gennarelli A T. Cerebral concussion and traumatic unconsciousness: Correlation of experimental and clinical observations on blunt head injuries. Brain. 1974, 97: 633-654
    [29] Abel J M, Gennarelli T A, and Segawa H. Incidence and severity of cerebral concussion in the rhesus monkey following sagittal plane angular acceleration. In: Proc of 22nd Stapp Car Crash Conference. Ann Arbor, Michigan,USA: Society of Automotive Engineers,1978, 35-53
    [30] Gennarelli T A, Thibault L E, Adams J, et al. Diffuse axonal injury and traumatic coma in the primate. Annals of Neurology, 1982,12: 564-574
    [31] Thibault L E, and Gennarelli T A. Biomechanics of diffuse brain injury. In: Proc of 29th Stapp Car Crash Conference. Washington DC: Society of Automotive Engineers, 1985
    [32] Margulies S S, and Thibault L E, A proposed tolerance criterion for diffuse axonal injury in man. J. Bomechanics, 1992, 25: 917-923
    [33] Lighthall J, Controlled cortical impact: A new experimental brain injury model. J. Neurotrauma, 1988, 5: 1-15
    [34] Gennarelli T, Thibault L, Tomei G, et al. Directional dependence of axonal brain injury due to centroidal and noncentroidal acceleration. In: Proc of 31st Stapp Car Crash Conference. New Orleans, USA: Society of Automotive Engineers, 1987, 49-53
    [35] Ross D T, Meaney D F, Sabol M, et al. Distribution of diffuse axonal injury following inertial closed head injury in miniature swine. Exp. Neurol, 1994,126: 291-299
    [36] Meaney D F, Smith D, Shreiber D, et al. Biomechanical analysis of experimental Diffuse axonal injury. Journal of Neurotrauma, 1995, 12: 689-694
    [37] Hodgson V R, and Thomas L M, Comparison of head acceleration injury indices in cadaver skull fracture. In: Proc of 15th Stapp Car Crash Conference. San Diego, USA: Society of Automotive Engineers, 1971, 190-206
    [38] Nahum A, Smith R and Ward C. Intracranial pressure dynamics during head impact. In: Proc of 21st Stapp Car Crash Conference. New Orleans, USA: Society of Automotive Engineers, 1977, 339-366
    [39] Kallieris D, Rizzetti A, Mattern R. Some observation to the skullbrain truma. In: Proc of AGARD/AMP Head Injury Specialists Meeting. Mescalero, NM,1996
    [40] Hardy W N, Foster C D, King A I, et al. Investigation of brain injury kinematics: Introduction of a new technique. In: Proc of Crashworthiness, Occupant protection and Biomechanics in Transportation Systems. New York: ASME, 1997,241-254
    [41] King A I, Yang K H, Hardy W N, et al. Challenging problems and opportunities in impact biomechanics. In: Proc of 1999 Bioengineering Conference, NewYork: ASME, 1999, 269-272
    [42] Ljung C. A model for brain deformation due to rotation of the skull. J. Biomechanics. 1975, 8: 263-274
    [43] Margulies S. Biomechanics of traumatic coma in the primate:[dissertation]. Philadelphia: University of Pennsylvania,1987, 20-56
    [44] Margulies S, Thibault L and Gennarelli T. Physical model simulations of Brain injury in the primate. Journal of Biomechanics, 1990, 23: 823-836
    [45] Nusholtz G, Glascoe L and Wylie E. Modeling cavitation during head impact. In: Proc of AGARD/AMP Head Injury Specialists Meeting. Mescalero: ASME,1996
    [46] Cha H S and Liu Y K. The symmetric response of a fluid-filed spherical shell-a mathematical simulation of a glancing blow to the head. J. Biomechanics, 1974, 7: 43-59
    [47] Khalil T B, Goldsmith W and Sackman J L. Impact on a model head-helmet system. International Journal of Mechanical Sciences, 1974, 16: 609-625
    [48] King A I and Chou C C. Mathematical modeling, simulation and experimental testing of biomechanical system crash response. J. Biomechanics, 1976, 9: 310-317
    [49] Shugar T. and Katona M. Development of a finite element head injury model. ASCE Journal of Eng. Mech, 1975, EM3(E101/173): 223-239.
    [50] Hosey R R and Liu Y K. A homeomorphic finite element model of the human head and neck. Finite element in biomechanics. New York: Wiley, 1982,379-401
    [51] Ruan J S, Khalil T, and King A. Dynamic head response of the head to impact by three dimensional finite element analysis. ASME J. Biomech. Eng. 1994,116: 44-50
    [52] Bandak F and Eppinger R. A three-dimensional FE analysis of the human brain under combined rotational and translational accelerations. In: Proc of 38th Stapp Car Crash Conference. Florida: Society of Automotive Engineers, 1994, 145-163
    [53] Bandak F, Vandervorst M, Chilton W, et al. An imaging-based computational and experimental study of skull fracture: Finite element model development. J Neurotrauma, 1995, 12(4): 679-688
    [54] Willinger R, Taleb L and Kopp C. Modal and temporal analysis of head mathematical models. J. Neurotrauma, 1995, 12:743-754
    [55] Al-Bsharat A, Hardy W N, Yang K H, et al. Brain/skull relative displacement magnitude due to blunt head impact: New experimental data and model. In:Proc of 43rd Stapp Car Crash Conference. San Diego: Society of Automotive Engineers, 1999, 321-332
    [56] Gurdjian E S and Lissner H. Mechanism of head injury as studied by the cathode ray oscilloscope, preliminary report. J. Neurosurg, 1944,1:393-399
    [57] Holbourn A. Mechanics of head injuries. The Lancet, 1943,2: 438-441
    [58] Lissner H, Lebow M and Evans F. Experimental studies on the relation between acceleration and intracranial pressure changes in man. Surgery, Gynecology and Obstetrics, 1960, 18(1): 58-60
    [59] Kopecky J A and Ripperger E A. Close brain injury: An engineering analysis. J. Biomech., 1969,2: 29-34
    [60] Gurdjian E. Recent advances in the study of the mechanism of impact injury of the head - a summary. Clin. Neurosurg, 1972,18: 1-42
    [61] Edberg S, Rieker J and Angrist A. Study of impact pressure and acceleration in plastic skull models. Labs. Invest., 1963,12: 1305-1311
    [62] Fujiwara S, Yanagida Y and Mizoi Y. Impact imduced intracranial pressure caused by an accelerated motion of the head or by skull deformation: An experimental study using physical models of the head and neck, and ones of the skull. Forensic Science International, 1989,43: 159-169
    [63] Gross A G. Impact thresholds of the brain concussion. J. Aviation Medicine. 1958,29: 725-732
    [64] Ommaya A K and Hirsch A.E. Tolerance for cerebral concussion from head impact and whiplash in primates. J. Biomechanic, 1971, 4: 13-21
    [65] Lindenberg R and Freytag E. The mechanism of cerebral contusions. Archives of Pathology, 1960,69: 440-469
    [66] Yanagida Y, Fujiwara S and Mizoi Y. Differences in the intracranial pressure caused by a `blow' and/or a `fall'-an experimental study using physical models of the head and neck. Forensic Sci Int., 1989,41(1-2): 135-145
    [67] Gennarelli T, Thibault L and Ommaya A. Pathophysiologic responses to rotational and translational accelerations of the head. In: Proc of 15th Stapp Car Crash Conference. Detroit, USA: Society of Automotive Engineers, 1972, 296-308
    [68] Brun-Cassan F, Fayon A and Tarriere C. Tolerance of the human head at impact: Reconstruction of head impacts observed in true-life accidents. In: Proc of Seminar on The Biomechanics of Impacts in Road Accidents. Brussels: EEVC,1983
    [69] McLean J. Brain injury without head impact. Journal of neurotrauma, 1995,12(4): 621-625
    [70] Willinger R, Kopp C and Cesari D. New concept of contrecoup lesion mechanism; modal analysis of a finite element model of the head. In: Proc. of International IRCOBI Conference on the Biomechanics of Impacts. Verona, Italy: IRCOBI, 1992, 283-297
    [71] Willinger R, Ryan G, McLean A, et al. Mechanisms of brain injury related to mathematical modelling and epidemiological data. In: Proc of International IRCOBI Conference on the Biomechanics of Impacts. Verona, Italy: IRCOBI, 1992, 179-192
    [72] Willinger R, Taleb L, Viguier P, et al. Rotation translation duality in head trauma perceptive and objective evidence. In: Proc of International IRCOBI Conference on the Biomechanics of Impacts. Lyon, France: IRCOBI, 1994, 63-76
    [73] Stalnaker R, Melvin J, Nusholtz G, et al. Head impact response. In: Proc of 21st Stapp Car Crash Conference. New Orleans: Society of Automotive Engineers, 1977, 305-335
    [74] Gadd C. Use of weighted-impulse criterion for estimating injury hazard. In: Proc of 10th Stapp Car Crash Conference. New Mexico: Society of Automotive Engineers,1966, 164-174
    [75] Versace J. A review of severity index. In: Proc of 15th Stapp Car Crash Conference. San Diego: Society of Automotive Engineers, 1971, 771-796
    [76] Newman J. A generalized acceleration model for brain injury threshold (GAMBIT). In: Proc of International IRCOBI Conference on the Biomechanics of Impact. Zurich: IRCOBI, 1986, 121-131
    [77] Eppinger R and Takhounts E. SIMon theoretical manual. Warrendale: NHTSA,2001, 1-15
    [78] Newman J, Shewchenko N and Welbourne E. A proposed new biomechanical head injury assessment function | the maximum power index. In: Proc of 44th Stapp Car Crash Conference. Atlanta: Society of Automotive Engineers, 2000, 215-247
    [79] Viano D. Biomechanics of head injury - toward a theory linking head dynamic motion, brain tissue deformation and neural trauma. In: Proc of 32nd STAPP Conference. Atlanta: Society of Automotive Engineers, 1988, 1-20
    [80] King A I, Yang K H, Zhang L Y, et al. Is head injury caused by linear or angular acceleration. In: Proc of International IRCOBI Conference on the Biomechanics of Impact. Lisbon: IRCOBI, 2003, 1-12
    [81] Yoganandan N, Pintar F A, Sances A Jr, et al. Biomechanics of Skull Fracture. Journal of Neurotrauma. 1995,12(4): 659-668
    [82] Allsop D L, Perl D R and Warner C Y. Force/deflection and fracture characteristics of the tomporo-parietal region of the human head. In: Proc of 35th Stapp Car Crash Conference. San Diego: Society of Automotive Engineers, 1991, 269-278
    [83] Yang J K. Review of injury biomechanics in car-pedestrian collisions. Int. J. Vehicle safety, 2005, 1: 100-116
    [84] L?venhielm P. Strain tolerance of the Vv. Cerebri Sup. (bridging veins) calculated from head-on collision tests with cadavers. Z. Rechtsmedizin , 1974, 75(2):131-144
    [85] Lee M C and Haut R C. Insensitivity of tensile failure properties of human bridging veins to strain rate: Implications in biomechanics of subdural hematoma. J. Biomech. 1989, 22 (6/7): 537-542
    [86] Gilchrist M, O'Donoghue D and Horgan T. A two-dimensional analysis of the biomechanics of frontal and occipital head impact injuries. Int. J. Crashworthiness, 2001,6(2): 253-262
    [87] Nishimoto T and Murakami S. Direct impact simulations of diffuse axonal injury by axial head model. JSAE Review, 2000, 21: 117-123
    [88] Hardy C and Marcal P. Elastic analysis of a skull. J. Appl. Mech, 1973: 838-842
    [89] Ward C and Thompson R. The development of a detailed finite element brain model. In: Proc of 19th Stapp Car Crash Conference. San Diego: Society of Automotive Engineers, 1975, 641-674
    [90] Nahum A, Simth M D. An experimental model for closed head impact injury. In: Proc of 20th Stapp Car Crash Conference. Dearborn: Society of Automotive Engineers, 1976, 785-814
    [91] Ward C, Chan M and Nahum A. Intracranial pressure-A brain injury criterion. In: Proc of 24th Stapp Car Crash Conference. Troy, Michigan: Society of Automotive Engineers, 1980, 163-185
    [92] Khalil T B, Viano D C. Critical issues in finite element modeling of head impact. In: Proc of 26th Stapp Car Crash Conference. Michigan: Society of Automotive Engineers, 1982, 87-102
    [93] Mendis K. Finite element Modeling of the brain to establish diffuse axonal injury Criterion: [dissertation]. Columbus: Ohio State University,1992, 15-40
    [94] Ruan J S, Khalil T and King A I. Human head dynamic response to side impact by finite element modeling. ASME Journal of Biomechanical Engineering, 1991, 113: 276-283
    [95] Ruan J S, Khalil T and King A. Finite element modeling of direct head impact.In: Proc of 37th Stapp Car Crash Conference. San Antonio: Society of Automotive Engineers, 1993, 69-81
    [96] DiMasi F, Eppinger R and Bandak F. Computational analysis of head impact response under car crash loadings. In: Proc of 39th Stapp Car Crash Conference. San Diego: Society of Automotive Engineers, 1995, 425-438
    [97] Zhou C. Finite element modeling of impact response of an inhomogeneous brain: [dissertation]. Detroit: Wayne State University,1995,14-72
    [98] Al-Bsharat A, Zhou C, Yang K H, et al. Intracranial pressure in the human head due to frontal impact based on a finite element model. In: Proc of Bioengineering Conference. New York: ASME, 1999, 113-114
    [99] Krabbel G and M?uller R. Development of a finite element model of the head using the visible human data. In: Proc of Visible Human Project Conference. Maryland: Berlin Univ. of Tech & Swiss Inst,1996
    [100] Kang H, Willinger R and Diaw B M. Validation of a 3d anatomic human head model and replication of head impact in motorcycle accident by finite element modeling. In: Proc of 41st Stapp Car Crash Conference. Florida: Society of Automotive Engineers, 1997, 329-338
    [101] Zhang L Y, Yang K H, Dwarampudi R, et al. Recent advances in brain injury research: A new human head model development and validation. Stapp Car Crash Journal, 2001, 45: 369-393
    [102] Baumgartner D, Willinger R, Shewchenko N, et al. Tolerance limits for mild traumatic brain injury derived from numerical head impact replication. In: Proc of International IRCOBI Conference on the Biomechanics of Impacts. Isle of Man, UK: IRCOBI, 2001, 353-355
    [103] Brands D. Predicting brain mechanics during closed head impact- numerical and constitutive aspects: [dissertation]. Eindhoven: Technische Universiteit Eindhoven,2002, 10-50
    [104] Claessens, M. Finite Element modeling of the human head under impact conditions: [dissertation]. Eindhoven: Technische Universiteit Eindhoven, 1997, 1-55
    [105] Brands D, Peters G and Bovendeerd P. Design and numerical implementation of a 3D non-linear viscoelastic constitutive model for brain tissue during impact. Journal of Biomechanics, 2004, 37: 127-134
    [106] 何黎民.头颈三维有限元模型构建及颅脑直接冲击伤致伤机制研究:[博士学位论文].上海:第二军医大学,2004,1-61
    [107] 马春生,张海钟,杜汇良等.具有解剖基下颌的人体头部有限元模型的建立.生物医学工程学杂志, 2005, 22 (1): 53-56
    [108] 何培,张建国,阮世捷等.基于螺旋 CT 的人体颅脑三维有限元模型构建.天津科技大学学报, 2006, 21 (2):36-38
    [109] Wood J L. Dynamic response of human cranial bone. J. Biomechanics, 1971, 4(3):1-12
    [110] Willinger R, Ryan G A, McLean A J, et al. Mechanisms of brain injury related to mathematical modeling and epidemiological data. Accident Analysis and Prevention, 1994, 26: 767
    [111] Horgan T J. A finite element model of the human head for use in the study of pedestrian accidents: [dissertation]. Dublin: National University of Ireland, 2005, 138-140
    [112] Kleiven S, Hardy W N. Correlation of an FE model of the human head with local brain motion consequence for injury prediction. Stapp Car Crash Journal, 2002,46: 123
    [113] Willinger R, Baumgartner D, Chinn B, et al. Head tolerance limits derived from numerical replication of real world accidents. In: Proc of International IRCOBI Conference on the Biomechanics of Impacts. Montpellier: IRCOBI, 2000, 209-221
    [114] Trosseille X, Tarriere C, Lavaste F, et al. Development of a F.E.M. of the human head according to a specific test protocol. In: Proc of 36th Stapp Car Crash Conference. Seattle, USA: Society of Automotive Engineers, 1992, 235-253
    [115] Turquier F, Trosseille X, Lavaste F, et al. Validation study of a 3D finite element head model against experimental data. In: Proc of 40th Stapp Car Crash Conference. Albuquerque: Society of Automotive Engineers, 1996, 283-294
    [116] Yang J.K., Xu W, Xiao Z. A study on head injury biomechanics in car-to-pedestrian collisions using human body models. In: Proc of XXI Congress, International Society of Biomechanics. Taipei: Journal of Biomechanics, 2007, S87.
    [117] Otte D, Krettek C, Brunner H, et al. Scientific approach and methodology of a new In-depth investigation study in Germany so called GIDAS. In: Proc of 18th ESV Conference. Nagoya: NHTSA, 2003, 1-17
    [118] TNO Automotive. MADYMO Theory Manual. Version 6.2.1. Delft, The Netherlands: TNO Road-vehicles Research Institue, 2004, 1-347
    [119] Yang J K, Lovsund P, Cavallero C, et al. A human-body 3D mathematical model for simulation of car-pedestrian impacts. J. Crash Prevention and Injury Control, 2(2): 131-149
    [120] Van Rooij L, Bhalla K, Meissner M, et al. Pedestrian crash reconstruction using multi-body modeling with geometrically detailed, validated vehicle models and advanced pedestrian injury criteria. In: Proc of 18th International Technical Conference on the Enhanced Safety of Vehicles, Nagoya, Japan: NHTSA, 2003:1-19
    [121] Pritz H B. Experimental investigation of pedestrian head impacts on hoods and fenders of production vehicles. In: Proc of Pedestrian Impact Injury & Assessment, SAE Int. Congress and Exposition. Warrendale: Society of Automotive Engineers, 1983, 67–76
    [122] Cavallero C, Cesari D, Ramet M. Improvement of pedestrian safety: Influence of shape of passenger car-front structures upon pedestrian kinematics and injuries: Evaluation based on 50 cadaver tests. In: Proc of Pedestrian Impact Injury & Assessment, SAE Int. Congress Exposition. Warrendale: Society of Automotive Engineers, 1983, 225–237
    [123] Mizuno Y and Ishikawa H. Summary of IHRA pedestrian safety WG activities-proposed test methods to evaluate pedestrian protection afforded by passenger cars. In: Proc of 17th ESV Conference. Amsterdam, Netherlands: NHTSA, 2001, 280
    [124] Okamoto Y, Kikuchi Y. A study of pedestrian head injury evaluation method. In: Proc of International IRCOBI Conference on the Biomechanics of Impacts. Madrid, Spain: IRCOBI, 2006, 265-276
    [125] Kong C Y, Yang J K, Li L, et al. In-depth investigation of vehicle traffic injuries in Changsha of China. In: Proc of 2nd International Expert Symposium of Accident Research Conference. Hannover: ESAR, 2006, 38-46
    [126] Sun D Z, Andrieux F, Ockewitz A, et al. Modeling of the failure behaviour of windscreens and component tests. In: Proc of LS-DYNA anwenderforum, Bamberg: LSTC, 2005, 23-32
    [127] Du Bois P A, Kolling S, Fassnacht W. Modeling of safety glass for crash simulation. Computational materials science, 2003, 28: 675-683
    [128] Yao J F, Yang J K, Otte D. Investigation of brain injuries by reconstructions of real world adult pedestrian accidents. In: Proc of International IRCOBI Conference on the Biomechanics of Impacts. Madrid, Spain: IRCOBI, 2006, 241-252

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700