用户名: 密码: 验证码:
不同灸材腧穴热敏化感传现象的观察及理化效应研究
详细信息    本馆镜像全文|  推荐本文 |  |   获取CNKI官网全文
摘要
腧穴热敏化艾灸具有调控人体机能的作用,对于一些患者体表上也以找到腧穴热敏化现象,进而采用腧穴热敏化艾灸治疗,能提高临床疗效,改善患者生存质量,具有临床的应用价值。
     但艾灸疗法在进行过程中,所产生的烟味和艾离子粘着于周遭环境的污染,病人因而产生不适感,影响就病意愿及依从性是灸疗的一大障碍。故以不同的灸材来进行腧穴热敏化艾灸,观察是否同样能有腧穴热敏化现像,出现循经感传,透热、扩热、传热、局部不(微)热远部热、表面不(微)热深部热、非热感觉等热敏灸感和经气传导等临床疗效的观察。观察运用不同的灸材影响机体出现腧穴热敏化现象的因素影响情况,进而能有利于推广腧穴热敏化艾灸于一般民众。
     目的
     从不同灸材的物理光热效应研究及透过不同灸条中的挥发油化学成份分析,观察五种不同灸材临床腧穴热敏化艾灸治疗时,腧穴热敏化现像,出现循经感传效应的探讨,提供临床研究的客观科学理论依据.
     方法
     实验一借由不同临床使用的不同艾条中(江西热敏灸条,汉医三年陈艾条,华陀太乙药艾)内容物的化学成份分析,比较不同艾条的化学有效成份多寡:
     实验二观察不同灸材(江西热敏灸条,汉医三年陈艾,华陀太乙药艾,无烟蕲艾,坛香线香等五种灸材的光热实验,)定时的放热能量及光热辐射现像以期能结合第三部份临床的腧穴热敏化的感传现像观察,以探讨影响腧穴热敏化中,艾条挥发油中化学成份多寡是否为影响腧穴热敏化的感传现像主要原因,不同艾条中不同的成份因为制作工艺的差异及使用的艾叶艾绒的不同是否会影响临床腧穴热敏化的感传,实验一用水蒸气蒸馏法参照中华人民共合国中华大药典2010版设定提存条件,再用GC-MS气相质谱联用仪分析不同艾条的主要化学成份。实验二研究不同灸材的光热效应观察不同灸材的定时放热热量及热辐射现像,结合第三部份的临床观察,以期在提供临床施术医生的新思维.
     临床研究方法:将150例次患者分为:将150例次患者分为汉医牌三年陈艾30例,华陀牌太乙药艾30例,上官式无烟天然蕲艾30例,台湾产沉檀香线香30例,热敏灸条组30例。分别使用不同的灸材施行腧穴热敏化艾灸治疗,观察不同灸材的热敏灸感和经气传导等临床现象。
     结果
     不同艾条的挥发油化学成份分析:用气相色谱一质谱法从中鉴定热敏灸艾条,汉医三年陈艾条,华陀太乙药艾条艾叶挥发油的化学成分数目分别为4、11、17。总归一化含量分别为100%、72.86%、55.48%。
     不同灸材的物理光热效应分析:由水吸热热量等于灸条向下热对流放热热量15min江西热敏灸条放热最高1800焦耳,30min江西热敏灸条放热最高3000焦耳,45min坛香线香放热最高5100焦耳;烧杯吸热量等于灸条向外热辐射放热热量15min无烟蕲艾条放热最高1822.5648焦耳,30min无烟蕲艾条放热最高4165.862焦耳0,45min无烟蕲艾条放热最高4513.018焦耳。
     临床研究:综合临床观察,五组患者在年龄、性别及病种构成方面比较均无显着性差异;五组患者在年龄、性别及病种构成方面比较均无显着性差异(P>0.05),提示两组的一般情况具有可比性。五种灸材的感传率差异不大,五组研究对象,经五种不同材质灸材施灸后产生的感传率比较,经卡方检验,差异无统计学意义(P>0.05)。五组研究对象,经五种不同材质灸材施灸后产生的不同感传现象分布比较,经卡方检验,差异有统计学意义(P<0.05)。
     结论
     1.艾条的挥发油化学成份分析:结果表明三种不同的灸条可能采用不同产地艾叶制作而成,植物生长环境(如海拔高度、温度、湿度、日照等)都直接影响其挥发油成分,三年陈艾条与太乙药艾条相同的成份较多,都含有大量的桉叶油素与Caryophyllene石竹烯,Camphor樟脑,3-环己烯-1-醇,4-甲基-1-(1-甲基乙基)-,(R)-,结果显示三年陈艾与太乙药艾有较相似的化学成份;而热敏灸艾条中的挥发油成份出峰时间在17.491min前皆未发现,显示其内容物的挥发油化学成份为较高沸点,可能与之选择精制艾绒为内容物有关
     2.灸材的物理光热效应分析:实验结果可知,热敏灸条在短时间向下对水产生热对流放热热量最大,檀香线香于30min至45min时水温差急据变化提式檀香线香的热量释放的累积性较强.显示热敏灸条在短时间的近红外线辐射较强能快速使深部六公分的水面下升温快速,而檀香线香的热力供给的续航力较强,结果说明短时间内无烟蕲艾的光热辐射效应最大,依次为檀香线香再者才为其它三种灸条,可能与无烟蕲艾及檀香线香制作有关,两者的材质致密度都比三种灸条大的多,使其火力短期爆发力强,但随着时间的拉长,灸条延续性热力持续出现,慢慢表现出较强的热力续航力。
     3.综合临床观察,五组患者在年龄、性别及病种构成方面比较均无显着性差异;五种灸材的感传率差异不大,然而六种感传现像具体比较中差异颇大,若以每种感传现象出现一次以一积分为基准,每组30例次6种感传现象,故共有180积分,以此为基础,表5中显示:热敏灸组,三年陈艾组,太乙药艾组,无烟蕲艾组,檀香线香组积分分别为:42,102,84,73,82.三年陈艾组总体感传现象最明显,依次为太乙药艾组>檀香线香组>无烟蕲艾组>热敏灸组.热敏灸组的感传积分为最低。
Heat-sensitive Moxibustion regulation of the human body functions with the role, for some patients also find the acupoints on the body surface thermal phenomenon, and then using thermal shu points of moxibustion treatment can improve the clinical efficacy, improve patient quality of life with clinical application. However, during the course of moxibustion therapy and the resulting smoke and Ai ion adhesion to the surrounding environment, pollution, and thus produce patient discomfort and affect the willingness and compliance of the disease is a major obstacle to moxibustion. Therefore, different thermal moxibustion materials to be shu points of moxibustion, and see if the same thermal technology have shu points are like, there PSC by transfer, through heat, thermal expansion, heat transfer, local non-(micro) heat Ministry of heat away, the surface is not (micro) heat deep heat, heat sensation and other non-thermal moxibustion flu and by air conduction and other clinical observations. Observe the use of different materials affect the body appears shu points moxibustion heat-sensitive factors of the phenomenon of the situation, and thus can help to promote thermal shu points in the general population of moxibustion.
     objective
     Moxibustion materials from different physical effects of light and heat and cauterize through different chemical composition of the volatile oil analysis, e observation of five different clinical materials moxibustion moxibustion of acupoint thermal treatment, thermal acupoints as of now, there PSC by traditional effect of providing an objective clinical study based on scientific theory.
     Method
     A clinical experiment by the use of different articles in different Ai (Jiangxi thermal cauterize, Chinese herbal medicine and three years of Chen Ai, Ai Hua Tuo Tai-drug) content analysis of the chemical composition, comparing different moxa amount of chemical active ingredients;
     Experiment 2:five moxibustion materials used include:Jiangxi thermal cauterize, Chinese Medicine for three years Chan Ai, Ai Hua Tuo Tai-drug, non-smoking Artemisia Artemisia vulgaris, altar incense incense moxibustion materials such as light and heat of five experiments, observed moxibustion heat energy and material timing is as light and heat radiation can be combined with the third part of the clinical shu points of the sense of thermal mass is observed as to explore the influence of the thermal shu points, moxa chemical composition of essential oil is affecting the amount Yu Point thermal mass of the flu as the main reasons are different in different moxa production process because of differences in composition and use of moxa leaves of different clinical shu points will affect the thermal transmission of the flu, a steam distillation experiments Law of the People of the United Nations refer to the Chinese Pharmacopoeia 2010 edition defined contribution great condition, and then GC-MS gas mass spectrometer analysis of different Ai's main chemical ingredients. moxibustion materials experiment two different effects of light and heat moxibustion materials observed Timing exothermic heat and thermal radiation are like, combined with the third part of the clinical observations, in order to provide clinical facilities in the operation of the new thinking of a doctor. Clinical Research:The 150 cases were divided into:A. Chinese herbal medicine and a license for three years 30 cases of Ai Chen, B. Hua Tuo Brand Tai-30 cases of drug Ai, C. Shangguan-style smoke-free 30 cases of natural Artemisia Artemisia vulgaris, D. Taiwan 30 cases of sandalwood incense production Shen, E thermal cauterize group of 30 patients, were implemented using different materials moxibustion moxibustion treatment of acupoints thermal effects of various thermal moxibustion moxibustion materials being and clinical observation by air conduction, etc.
     Results
     1. Different moxa the chemical composition of essential oil:a gas chromatography mass spectrometry identified from thermal moxibustion Ai, Ai Chen Chinese Medicine article three years, and Hua Tai-medicine moxa leaves the number of the chemical constituents of volatile oil were 4,11,17. Census drawn from a content of 100%,72.86%,55.48%.
     2. Moxibustion materials with different physical light and heat effect analysis: the water absorbs heat energy equal to cauterize down hot hot heat of the exile 15min Jiangxi thermal heat to cauterize the maximum 1,800 joules,30min Jiangxi thermal heat to cauterize the maximum 3,000 joules,45min altar incense incense 5100 Joule heat up; beaker is equal to cauterize heat absorption heat of the heat radiation from outside smoke-free Artemisia moxa 15min highest 1822.5648 Joule heat,30min Artemisia moxa smoke-free heat of the highest 4165.862 joules 0,45 min smoke-free Artemisia moxa heat up 4513.018 joule
     3. Clinical research:Comprehensive clinical observation, five patients in age, sex and disease composition There were no significant differences; five groups in age, sex and disease composition showed no significant difference (P>0.05), suggesting that the general situation of the two groups were comparable. Five sense material transfer rate moxibustion little difference, five subjects, five different materials by moxibustion moxibustion materials resulting from the flu transmission rates compared by Chi-square test, the difference was not statistically significant (P> 0.05). Five subjects, five different materials by moxibustion moxibustion materials resulting from the distribution of different Sensations compared by chi-square test, the difference was statistically significant (P<0.05)
     Conclusion
     1. Moxa chemical composition of volatile oil analysis:The results showed that three different cauterize the leaves may be made of different origin, plant growth environment (such as altitude, temperature, humidity, sunshine, etc.) directly affect the volatile oil, three In Chen and Tai-medicine moxa moxa same ingredients more, are high in eucalyptol and caryophyllene Caryophyllene, Camphor camphor,3-cyclohexene-1-ol,4-methyl-1-(1-methyl-ethyl)-, (R)-, the results show that three years and the Tai-Chen Ai Ai drugs have a more similar chemical composition; and thermal moxibustion moxa in peak time of volatile oil components are in 17.491min ago not found, display the contents of the volatile oil chemical composition as the high boiling point, may be refined with moxa for the content of selected objects
     2. Moxibustion materials physics of light and heat effect analysis:the experimental results, thermal cauterize down in a short time on the water will be hot hot heat of the exile, the largest sandalwood incense in 30min to 45min when the water temperature according to changes in acute type sandalwood incense to mention the cumulative heat release is strong. show thermal cauterize the near-infrared radiation in a short time can quickly make a strong six centimeters deep below the surface temperature rapidly, while the heat supply of sandalwood incense life strong, results indicate that short time, smoke-free Artemisia Ai radiation effects of light and heat the most, followed by addition of sandalwood incense before the other three cauterize, may be a smoke-free Artemisia Artemisia vulgaris and sandalwood incense produced, both material density of three to cauterize larger than more explosive force to fire short-term strength, but as time stretching, cauterize continuity continuous heat, heat slowly showed strong endurance.
     3. Comprehensive clinical observation, five patients in age, sex and disease composition showed no significant difference; five moxibustion materials being transfer rate is insignificant, but pass the six sense, as the comparison is quite different large, if each Sensations occur to an integral as a benchmark, with 30 cases each time 6 Sensations, so a total of 180 points this basis, Table 5 shows:thermal moxibustion group, three Chen Ai Group Ai Group Taiyi drugs, smoke-free Artemisia Ai Group, sandalwood incense set points were: 42,102,84,73,82. three years, Chen Ai Group's most significant transfer in the general sense, followed by Tai-drug Ai Group> sandalwood incense Group> Smoke-free Artemisia Ai Group> thermal moxibustion group. thermal moxibustion group's sense of the lowest mass points.
引文
[1]陈日新,康明非.热敏灸实用读本.人民卫生出版社.北京:2009,4-13
    [2]荣培晶.内脏痛与体表相关性的实验研究[J].中国病理生理杂志,2004,20(3):363-366.
    [3]付勇 康明非(指导).“热敏点”灸为主治疗GIDP 1例[J].江西中医药,2007,38(2):46-47.
    [4]李伟,王芳,黄建华.新灸法治疗日旋旋光性皮炎1例[J].江西中医药,2009(6):64-64.
    [5]张翠蓉.腧穴热敏灸外加中药外敷治疗压疮20例临床护理[J].齐鲁护理杂志,2008,14(6):42-42.
    [6]贺普仁.灸具灸法.科学技术文献出版社.北京:2004,72-77
    [7]陆寿康.刺法灸法学.中国中医药出版社.北京:83-87
    [8]Yin GM, Sun N, Zhu JZ, et al. Extraction of volatile components of folium artemisiae argyi and an alysis by gas chromatography/mass spectrometry. Chin J Anal Chem,1999,27(1):55-58.
    [9]欧明,林励,李衍文.简明中药成分手腮[M].北京:中国医药科技出版社,2003:101—103.
    [10]洪宗国,农熠瑛,杨兆涛.蕲艾燃烟化学成分的GC—MS分析[J].中南民族大学学报(自然科学版),2007,26(1):10-11.
    [11]黄秋风译.艾的有机成分[J].国外医学·中医中药分册,1989,11(5):47
    [12]全国中草药汇编(上册)[M].北京:人民卫生出版社,1976:271
    [13]颜正华.中药学[M].北京:人民卫生出版社,1991:518-518.
    [14]洪宗国,余学龙,陈艺球.蕲艾、北艾、川艾挥发油化学成分比较研究[T].中草药,1996,27(3):138-140.
    [15]许成坤,聂桂玲.艾蒿.吉林农业[J].2002,7:17.
    [16]华东医院,上海市黄浦区妇女儿童保健所.上海市生物制品研究所.等.苍术艾叶烟熏消毒的实验研究及长期应用观察[J].中华医学杂志,1978,(10):619-623.
    [17]梅全喜.艾叶[M].北京:中国中医药出版社,1999:9-11,227-230.
    [18]刘国声.艾叶挥发油成分的研究[J].中草药,1990.21(9):8—9.
    [19]胡世林主编.中国道地药材.哈尔滨.黑龙江科技出版社。1989,501
    [20]邹菁 刘安昌 张平.活性离子水提取艾叶挥发油的研究[J].武汉化工学院学报,2006,28(4):27-30.
    [21]欧明,林励,李衍文.简明中药成分手册[M].北京:中国医药科技出版社,2003:101-103.
    [22]何正有张艳红魏冬等.三种不同提取方法制备的艾叶挥发油化学成分分析[J].中国医药生物技术,2008,3(4):284-288.
    [23]王强,罗集鹏.中药分析.中国医药科技出版社.北京:2005,147-158
    [24]顾一煌,金宏柱,任建宁等.艾灸对力竭运动小鼠血清肌酸激酶影响的实验研究[J].河南中医,2008,28(12):38-39.
    [25]张京英刘农虞.不同灸质,灸量对实验性阳虚大鼠中枢及外周5—HT代谢的影响[J].中医杂志,1996,37(2):111-112.
    [26]李守栋.艾灸的不同刺激量对雷公藤甲素毒副作用的影响[J].甘肃中医,2007,20(1):49-50.
    [27]张英 刘又香.不同灸治时程对阳虚小鼠免疫功能影响的比较[J].湖北中医杂志,1998,20(2):53-54.
    [28]李观荣 易群 等.艾灸灸量以唇红为度的初步观察[J].四川中医,2001,19(6):17-18.
    [29]徐维,陈正秋,阎亚生.热或艾油处理长强穴对大鼠痛反应的影响[J].针刺研究,1988,14(3):190.
    [30]邓海平,沈雪勇,丁光宏.艾灸与经络穴位红外辐射特性.中国针灸,200,1,24(2):105—108.
    [31]杨华元 肖元春 刘堂义 等.隔物灸的近红外光谱辐射特性测定[J].上海针灸杂志,2003,22(9):15-17.
    [32]钱存泽,钱进,白耀辉.近红外仿灸仪的研制与临床应用[J].红外·技术,1991,13(6):27.
    [33]杨文修.李正明主编.生物医学物理概论.天津:天津科技翻译出版公司.1993,4
    [34]陈德济.中医经络诊断系统及其应用前景.中医药工程研究与应用.北京:中国中医药出版社.1992,128
    [35]陈栋,寿小云.正常人体颜面温度分布及红外面像分析[J].激光与红外,1994,24(3): 52-56.
    [36]张栋,孟竞璧,高惠合等.经络温度特性的客观显示——针灸后循经温度变化的红外热像图表现.自然杂志,1989,12(11):845
    [37]张栋,薛立功,魏正岫等.面部皮肤温度与面部血流量关系的对照观察.生物医学工程学杂志,1999,16(1):81
    [38]汪培清,胡翔龙,吴宝华.人体背部循经红外辐射轨迹的显示.针刺研究,1993,18(2):90
    [39]张栋,付卫星,王淑友等.经脉温度特性的红外热像图显示.针刺研究,1996,21(3):63
    [40]张栋,付卫星,王淑友等.不同针灸方法诱发循经高温线现象的比较.中国针灸,2000,20(6):349
    [41]张栋,王淑友,王援朝等.循经高温线下深部组织温度的测定.中国中医基础医学杂志,2001,7(10):62
    [42]B.H.巴斯格罗夫斯基.建筑物理[M].北京:中国建筑工业出版社,1988.
    [43]许金森,汪培清等.冷负荷对人体体表循经红外辐射轨迹影响的初步观察[J].中国临床康复,2002,6(7):967-968.
    [44]张栋,王淑友等.体表不同温度区下深部温度的测定[J].北京生物医学工程,200l,20(4):288-291.
    [45]王本显.国外对经络问题的研究[M].北京:人民卫生出版社,1984.28~40,109~114.
    [46]赤羽幸兵卫着,刘芸卿等合译.知热感度测定法针灸治疗学[M].上海:上海卫生出版社,1956.1~122.
    [47]许帼光,汪崇淼.TCMD-型中医经络诊断仪诊断77例经络失衡现象的临床分析[J].中国针灸,1994,(增刊):402~403.
    [48]王丹芬,李振宇.疾病与两侧经穴皮温失衡的关系[J].河北中医学院学报.1995,10(2):36~38.
    [49]黄丽春,严智强.刺激耳穴对体穴温度变化的观察[J].中国针灸,1989,9(6):26-28.
    [50]王华.试论中医传感针在经络腧穴研究中的应用[J].中国中医药信息杂志,1996,3(11):10-11.
    [51]高凌云,胡翔龙,许小洋等.督脉循行线下深部组织温度的检测[J].针刺研究,2006,3l(3):159-162.
    [52]杨华元肖元春刘堂义等.隔物灸的近红外光谱辐射特性测定[J].上海针灸杂志,2003,22(9):15-17.
    [53]钱存泽,钱进,白耀辉.近红外仿灸仪的研制与临床应用[J].红外·技术,1991,13(6):27.
    [54]陈德济.中医经络诊断系统及其应用前景.中医药工程研究与应用.北京:中国中医药出版社.1992,128
    [55]张栋,付卫星,王淑友等.经脉温度特性的红外热像图显示.针刺研究,1996,21(3):63
    [56]张栋,付卫星,王淑友等.不同针灸方法诱发循经高温线现象的比较.中国针灸,2000,20(6):349
    [57]张栋,王淑友,王援朝等.循经高温线下深部组织温度的测定.中国中医基础医学杂志,2001,7(10):62
    [58]赤羽幸兵卫着,刘芸卿等合译.知热感度测定法针灸治疗学[M].上海:上海卫生出版社,1956.1~122.
    [59]许帼光,汪崇淼.TCMD-型中医经络诊断仪诊断77例经络失衡现象的临床分析[J].中国针灸,1994,(增刊):402~403.

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700