用户名: 密码: 验证码:
腹针疗法治疗高血压病的临床观察
详细信息    本馆镜像全文|  推荐本文 |  |   获取CNKI官网全文
摘要
理论背景:
     高血压病是临床常见病与多发病。在我国人口疾病构成中,心血管病发病率占居第一位(约占40%),而高血压又是引起心血管疾病最重要的危险因素。现代医学治疗本病已研制出多种控制血压的一线用药,如利尿剂、β-受体阻滞剂、钙离子拮抗剂(CCB)、血管紧张素转换酶抑制剂(ACEI)、血管紧张素Ⅱ受体拮抗剂(ARB)及α-受体阻滞剂等,并且已达到较好的临床疗效。
     在祖国医学中,已有较多、较好的方法治疗高血压病。而针灸疗法是祖国传统医学的重要组成部分,是一种疗效肯定的治疗方法。大量临床研究表明,中医针刺治疗原发性高血压病(Essential Hypertension,EH)能够取得良好疗效,降压平稳,并且已从微观角度阐明针灸降压的机理是多方面、多水平、多环节的调整作。
     腹针疗法是由北京中医药进修学院教授、腹针疗法培训中心主任薄智云教授创立的。通过20余年的临床证实,腹针对临床各系统疾病有着良好的疗效。本课题通过观察腹针治疗高血压病临床疗效,初步探讨其疗效的作用机理,以推广中医特色疗效在治疗慢性疾病方面的应用,提高临床疗效及患者生活质量。
     目的:
     观察腹针疗法治疗高血压病的临床疗效,并探讨其疗效的作用机理。
     方法:
     采用简单随机化方法将符合诊断纳入标准的60例患者分为治疗组与对照组,对照组30例予西医基础治疗,治疗组30例在西医基础治疗上予腹针治疗。腹针取穴:中脘(深刺),下脘(深刺),气海(深刺),关元(深刺),滑肉门(双侧,中刺),外陵(双侧,中刺),神灯照神阙穴。治疗一个疗程,共7天。分别在第1、2、3、5、7天进行腹针治疗,5次为一个疗程。观察治疗前后主要指标变化情况。治疗一个疗程后进行疗效评定,并进行临床安全性评价。
     结果:
     临床症状疗效:腹针组在改善高血压患者常见症状如头痛、失眠与对照组相比,P<0.05,有显著性差异。在有效率方面,腹针组显效19例,占63.3%,有效10例,占33.3%,无效1例,占3.3%,总有效率96.7%;对照组显效12例,占40.0%,有效14例,占46.7%,无效4例,占13.3%,总有效率86.7%。两组相互比较P<0.05,差异有显著性意义。
     临床降压疗效:腹针组显效15例,占50.0%,有效15例,占50.0%,总有效率100%;对照组显效14例,占46.7%,有效16例,占53.3%,总有效率100%,两组降压疗效比较P>0.05,差异无显著性意义。
Theory Background:Hypertension sickness is the common and frequently occurring illness in the clinic. Constitutes at our country population disease, angiocardiopathy disease incidence rate occupies ranks first (approximately composes 40%), but hypertension is the most important dangerous factor in causing the cardiovascular disease. In the modern medicine many kinds of controls blood pressure have been developed, such as the diuretic, β-blocker, CCB,ACEI,ARB and the α-blocking agent, and has achieved the good clinical curative effect.In the traditional medicine, there have many good methods to treat hypertension. And the acupuncture and moxibustion treatment is a part of traditional medicine science in the motherland, and a kind of treatment method with definite curative effect. In recent years, lots of clinical research indicated that the treatment of Essential Hypertension (EH) had gained good effect and steady blood pressure by acupuncture and moxibustion treatment, elucidated mechanism from microangle that acupuncture and moxibustion treatment step down pressure in many aspects, multilevel, many adjustment function of link.Abdominal Acupuncture Therapy is established by professor zhiyun Bo, which is the professor of Beijing advanced study institution of traditional Chinese medicine(TCM) and the master of training center of Abdominal Acupuncture Therapy. Through more than 20 years clinical confirmations, the clinical case vivificated that the Abdominal Acupuncture Therapy has a good treatment to many diseases. After observing the clinical effective of the
    abdominal acupuncture to the EH, we will explore the mechanism action in initial, this will do good to the application of the characteristic treatment of TCM in treating the chronic disease, enhancing the clinical curative effect and the patient quality of life.Objective:Observing the clinical effect of the abdominal acupuncture therapy to the EH, and discussing the action mechanism. Method:We will use the simple randomization method to divide the 60 cases to treatment group and control group which conforms to the diagnosis and brings into line standard, the control group(30 cases) will provided the basic medical drug treatment, the treatments group(30 cases) will provided abdominal acupuncture therapy at the foundation treatment of the basic medical drug. Acupucture point of abdominal acupuncture group: Middle Epigastrium(deep puncture), pylorus Xiawan point (deep puncture), Qihai region (deep puncture), Guanyuan(deep puncture), Huaroumen(twice, deep puncture), wailing (twice, deep puncture) , Shenque point(irradiated by lamp). It is a courses of treatment in 1 week, 5 times a course , one times a day, it will given treatment by abdominal acupuncture at the number one*, two, three, five and seven day. We will observe major targets transformation in before or after the treatment. When a course of the treatment is finished, we will evaluate curative effect and the clinic security. Result:Clinical effect in symptom: in improving the common symptom such as headache, agrypnia,the abdominal acupuncture group have a significant difference compare with the control group, P<0. 05. In the effective power, significant effect cases of abdominal acupuncture group is 19 and the rate is 63. 3%, effect rate cases is 10 and the rate is 33.3%, total effective rate is 96.7%;significant effect cases of control group is 12 and the rate is 40. 0%, effect cases is 14 and the rate is 46.7%, total effective rate is 86. 7%, there have a significant difference between the two groups, P<0.05.Clinical effect in cut down blood pressure: significant effect cases of abdominal acupuncture group is 15 and the rate is 50. 0%, effect rate cases is 15 and the rate is 50.0%, total effective rate is 100%;significant effect cases of control group is 14 and the rate is 46. 7%, effect cases is 16 and
    the rate is 53. 3%, total effective rate is 100%, there have not a significantdifference between the two groups, P>0. 05.Conclusion:The abdominal acupuncture group have a preferably effect in improving the common symptom of the hypertensive patient such as headache, dizziness, agrypnia compared with the control group though the total effect is equal. And the abdominal acupuncture has its own characteristic: handling convenie, anodynia, have no adverse reaction and this can be regarded as one of the characteristic treatment of TCM.
引文
[1] 中华人民共和国卫生部,卫生部心血管病防治研究中心,高血压联盟(中国).中国高血压防治指南(2005年修订版 全文),中国高血压防治指南修订委员会,http: //www. hzzj. com/zongshu/1004. htm.
    [2] HermanWW, Konzelman JL JR, Prisant LM, et al. New national guidelines on hypertension: a summary for dentistry. J Am Dent Assoc, 2004;135: 576-584.
    [3] 李为民,刘巍.高血压药物治疗的最佳选择.中国实用内科杂志,2006;26 (6):417-418.
    [4] 杨哲林,王焕文,张良纯等.高血压患者昼夜去甲肾上腺素分泌率与血压、心率动态监测.中华心血管病杂志,1993;21 (6):373.
    [5] Luft FC. Salt and hypertension: Recent advances and perspectives. J Lab Clin MED, 1989;114: 215-221.
    [6] De wardener HE. Kidney, salt intake, Na+ - k+ -ATPase inhibitors in hypertension. Hypertension, 1991;17: 830-836.
    [7] 谭军,李玲芝,于小亮.血清镁离子浓度对原发性高血压及其并发症影响的探讨.中国现代医学杂志,2001;11 (7):44-45.
    [8] 任骏,刘运德.饮食钙的摄入与高血压—基础与临床.心血管病学进展,1997;18 (3):151-155.
    [9] 刘治全,牟建军.高血压病诊断治疗学.北京:北京医科大学中回协和医科大学联合出版社,1998,17.
    [10] 王迪浔.病理生理学.北京:人民卫生出版社,1996,225.
    [11] 王迪浔.病理生理学.北京:人民卫生出版杜,1996,427.
    [12] 杨文杰,顾东风.人类原发性高血压侯选基因的研究进展.遗传,2001;23(5):487-491.
    [13] 叶任高.内科学.北京:人民卫生出版社,2000,第5版:260.
    [14] Bbckman C S, Joffries W B, Pettinger W A, etal. Enhanced release of endothelial derived relaxing factor in mineralocorticoid hypertension, 1992;20: 304-308.
    [15] Dananberg, Richard S. Sustained hypertension induced by orally administered nitro-L-arginine. Hypertension, 1993;21: 356.
    [16] Rapport RM, Murad F. Agonist induced endotheliumdePendent laxation in rat thotacic aorta may be mediated through cGMP. Circ Res, 1983;52: 352.
    [17] 邹宝明,江时森,李俭春.血花生四烯酸释放及其对高血压病的调节作用.中国危 重病急救医学,1996;8 (3):149-151.
    [18] 陈国伟,郑宗锣.现代心脏内科学.长沙:湖南人民出版社,1997,第1版:81.
    [19] Komori K, Vanhoulte PM. Blood vessels, 1990;27: 238-245.
    [20] 陈国栋.现代老年医学进展,北京:中国科学技术出版社,1996,193.
    [21] 余振球.实用高立压学.科学出版社,北京,第2版:1996,77.
    [22] 刘贺新.高脂血症与高血压的关系(社区研究).高血压杂志,2001;(4):348-349.
    [23] Kindy MS. Regulation of oncogene expression in cultured smooth muscle cells. J Biol Chem, 1986: 261(11): 12865-12868.
    [24] Banskota NK, Taub R, Zellner K, et al. Characterzation of induction of c-myc genes and cellular growth in human vascular smooth muscle cell by insulin and IGF-Ⅰ. Diabetes. 1989;38(1): 123.
    [25] Negoro N. Expression of c-myc proto-oncogene in heart and smooth muscle cells of SHR. Hypertension, 1988;6[Suppl 4] : 128.
    [26] The Seventh Report of the JointNational Committee on Prevention. Detection Evaluation, and Treatment of High Blood Pressure: the JNC7 report. JAMA, 2003;289: 2560 - 2572.
    [27] Morgensen CE, NeldamS, Tikkanen I, et al. Randomized controlled trial of dual blockade of rennin - angiotensin system in patients with hypertension, microalbuminuria, and non - insulindependent diabetes: the candesartan and lisinop ril microalbuminuria (CLAM) study. BMJ, 2001, 321: 1440 - 1444.
    [28] The Seventh Report of the JointNational Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC7 report. TAMA, 2003;289: 2560 - 2572.
    [29] 李光伟.胰岛素增敏剂对传统高血压治疗策略的挑战.中华心血管杂志,2003;31(8):637-639.
    [30] 冯金萍.高血压病中医研究进展.现代中西医结合杂志,2005;14(10):1386-387.
    [31] 袁卫红,贺泽龙.高血压病辨病辨证治疗思路探讨.湖南中医药导报,2000,6(5):10-11.
    [32] 徐树楠,刘海丽.高血压病的中医病理学特点探微.中国中医基础医学杂志,2003,9(9):650-651
    [33] 孙伯扬.高血压病的辨证论治[J].实用中西医结合杂志,1991,4 (5):260.
    [34] 吕志杰.降压延寿汤治高血压病87 例临床观察.新中医,1990;22 (11):22-24.
    [35] 张玲端,刘淑云,白智峰等.原发性和肾性高血压中医证候演变规律及实质的探讨.辽宁中医杂志,1992;19(9):18.
    [36] 周胜发.高血压与血瘀证.高血压杂志,1994;2 (4):276.
    [37] 张玲端,刘淑云,白智峰,等.原发性和肾性高血压中医证候演变规律与RAA 系统、心纳素的关系.天津中医,1993;10(1):21.
    [38] 宁选.老年高血压病中医治疗与血清微量元素的关系.中医研究,1991;4(1):21.
    [39] 李冬梅.高血压病中医研究进展.河南中医,2005;25(5):79-80.
    [40] 中华人民共和国卫生部制定发布.中药新药临床研究指导原则,1993;28.
    [41] 徐晓阳,高瑛.辨证治疗高血压病125例临床观察.天津中医,1998;15(2).63-64.
    [42] 邓祥雄,黄荣璋.天麻钩藤饮加减治疗高血压病63例.吉林中医药,2002;22 (3):10.
    [43] 陈康远.六味地黄丸加减治疗原发性高血压337例疗效观察.新中医,2003;35 (5):41-42.
    [44] 张治祥,封建涛,马宏秀.养阴活血汤治疗高血压病30例临床观察.现代中医药,2004;(3):25-26.
    [45] 张国伦,唐东明,林路.张国伦治疗高血压病经验.山东中医杂志,2004;23 (5):307-308.
    [46] 洪创维.参麦注射液治疗高血压病的临床观察.中西医结合心脑血管病杂志,2003;1(7):433.
    [47] 谭元生,郑圣明,谭超.复方七芍降压片治疗高血压病的临床疗效及机理研究.中成药,2004;26 (1):71-73.
    [48] 蔡光先,朱克俭,韩育明,等.高血压病常见证候临床流行病学观察.中医杂志,1999;40(8):492.
    [49] 齐冬梅,石作荣.活血化瘀法治疗老年人高血压病35例.山东中医药大学学报,1999;23(1):41-43
    [50] 王振涛,韩丽华.中医治疗高血压病若干思考.中国中西医结合杂志,2003;23(9):709-710.
    [51] 李运伦.黄连解毒汤加减治疗高血压病30例临床研究.国医论坛,2000;15(2):38-39.
    [52] 阁增民.针灸治疗高血压病66例.陕西中医,1994;15 (9):416.
    [53] 高建芸,赵京生,董煌.据人迎寸口脉法实施针刺补泻治疗高血压病临床研究,中国针灸,2001;21 (12):707-710.
    [54] 彭德军.太冲穴配足三里穴针刺治疗肝阳上亢型高血压52例.针灸临床杂志,2002;18 (2):38.
    [55] 王侠,邹旭,李松等.针刺太冲穴治疗高血压的临床研究.实用医学杂志,2003;19(5):565-566.
    [56] 周华.针刺内关、太冲穴治疗原发性高血压病的临床观察.上海针灸杂志,1997;16 (4):10.
    [57] 王光义,蒋乃昌,殷松生等.电针对急性实验性高血压大鼠的降压效应及中枢机制.中国针灸,1997;17(2):105-108.
    [58] 顾蕴辉,杨芝兰.电针刺激“听宫”穴引起降压反应的机理探讨.中国针灸,1998;18(3):167-169.
    [59] 蔡钦朝,童立应,吴云智.针刺对高血压病患者血管内皮细胞内分泌功能的调节作用.中国中医药科技,1998;5 (1):6-8.
    [60] 陈越峰,钱红.针刺对高血压病患者血浆内皮素、血管紧张素Ⅱ影响的研究.中国针灸,2000;(11):691-693.
    [61] 吴清明,冯国湘,汤雪飞,等.针刺开“四关”加百会穴温针灸对原发性高血压患者血浆中ET和NO的影响.中国针灸,2004;24 (1):53-55.
    [62] 张英,刘又香,潘克英.针刺、艾灸、针加灸对肾素-血管紧张素-醛固酮系统、心钠素含量影响的比较研究.湖北中医学院学报,2001;3 (2):20-21.
    [63] 刘丹,樊爽,慈玉莹.针刺对肾性高血压大鼠6-酮-前列腺素F1及血栓素B2影响的研究.针灸临床杂志,2003;19(8):69-70.
    [64] 陈琼,周逸平.针刺对高血压病患者血液流变学的影响.针灸临床杂志,1995;11(8):28.
    [65] 张英.不同针灸疗法影响高血压病患者甲璧微循环的比较研究.中国针灸,1994,增刊:149-151.
    [66] 殷之放,汪司右,肖达.项针疗法治疗高血压病临床观察.上海针灸杂志,2002;21 (5):10-11.
    [67] 汪司友,殷之放.针刺对高血压患者血流动力学的影响.上海针灸杂志,1993;12(4):143.
    [68] 胡洁.针刺对家兔心肌细胞游离钙镁浓度的影响.上海针灸杂志,1999;18 (3):30-32.
    [69] 杨帆等.择时针刺对高血压患者血压及血流动力学即时效应的影响.上海针灸杂志,2002;21 (2):8-9.
    [70] 陈邦国.子午流注针法降压作用的临床观察.湖北中医杂志,1997;19 (1):44.
    [71] 杨文英.80例健康人体躯干部经穴超微弱发光实验研究.深圳中西医结合杂志,1995;5 (3):1.
    [72] 杨文英,宋伟.130例健康人体四肢经穴超微弱发光实验研究.上海针灸志,1996;15(1):34-35.
    [73] 杨文英,倪秀冬.原发性高血压病人经穴超微弱发光光谱观察.中国中医基础医学杂志,1998;4 (8):49-51.
    [74] 薄智云.腹针疗法.北京:中国科学技术出版社,1999,第1版:2-9.
    [75] 周炜,王丽平.腹针治疗脑血管病后痉挛性瘫痪的疗效观察.中国针灸,2005; 25 (11):757-759.
    [76] 李建媛.腹针为主治疗中风偏瘫患肢水肿临床观察.北京中医药大学学报(中医临床版),2005;12 (4):32-33.
    [77] 李莉群,郭晓燕,彭印高.腹针治疗脑动脉流速异常89例临床分析.现代医院,2005;5 (11):56-57.
    [78] 孙善凤.腹针加TDP照射治疗痹证.辽宁中医杂志,2002;29 (4):217.
    [79] 范群,俞明.腹针疗法治疗四肢关节痛症176例临床研究.江苏中医药,2002;23(12):36—38.
    [80] 王志中,李君梅,李明.腹针治疗退行性膝关节病23例.针灸临床杂志,2002;18 (3):13—14.
    [81] 温卫萍.以腹针为主治疗肩凝症50例临床观察.针灸临床杂志,2003;19 (11):25.
    [82] 闪剑.腹针配合推拿治疗肩周炎163例报告.甘肃中医,2003;16 (12):22—23.
    [83] 陆永辉,王志红.腹针治疗肩凝症顽固性疼痛32例疗效观察.新中医,2004;36 (12):38—39.
    [84] 吕志灵.腹针治疗颈椎病46例.浙江中医学院学报,2006;30 (1):84.
    [85] 刘淳.腹针治疗颈椎病73例.针灸临床杂志,2001;17 (5):51—52.
    [86] 孙玲.腹针治疗神经根型颈椎病52例疗效观察.河北中医,2004;26 (4):281.
    [87] 王育庆,唐了香,潘长青.腹针疗法对腰椎间盘突出症患者疼痛症状的改善作用.中国临床康复,2005;9 (38):122-123.
    [88] 薄智云,牛庆强,朱文罡.腹针治疗神经根型颈椎病多中心对照研究.中国针灸,2005;25 (6):387-389.
    [89] 莫晓枫.腹针治疗腰椎间盘突出症36例.浙江中医学院学报,2001;25 (5):59.
    [90] 周佐涛,林晓山.腹针治疗腰椎间盘突出症42例疗效观察.上海针灸杂志,2004;23 (2):13—14.
    [91] 朱文罡,刘光英,任连芳.腹针治疗腰椎间盘突出症的临床研究.针灸临床杂志,2004;20 (9):23.
    [92] 郭万刚,马林儒,弓利风,等.腹针为主治疗腰椎间盘突出症50例疗效观察.中国针灸,2003;23 (3):145—146.
    [93] 朱文里,顾群,孟凡军,等.腹针治疗面肌痉挛19例.中国针灸,2004;24 (4):237.
    [94] 徐丽华,郭奕文,张斌,等.腹针配合隔姜灸治疗难治性周围性面神经麻痹20例.河南中医,2005;25 (12):64-65.
    [95] House J. Facial nerve grading system. Aryngoscope, 1983;93 : 1056 - 1068.
    [96] 陈丽贤,丁晓虹.腹针治疗脑梗死50例.中国临床康复,2004;(19):3823.
    [97] 韩莉,韩里.浅谈腹针加拔罐治疗痞闭临床体会.中华综合医学杂志,2003;2(8):65.
    [98] 李德平,王宝玲.腹针治疗抑郁症44例.上海针灸杂志,2005;24 (3):22
    [99] 林庆.腹针治疗功能性便秘(慢传输型)48例临床观察.中国中医药科技,2005;12 (6):393-394.
    [100] 韩燕.腹针疗法调冲任治疗继发性闭经33例的临床报道.针灸临床杂志,2002;18 (8):3—4.
    [101] 黄丽,卢琰.腹针治疗月经不调78例.光明中医,2005;20 (6):55.
    [102] 薄智云.神阙布气说与腹针的关系.北京中医杂志,1993;(4):13-14.
    [103] 王丽平.薄氏腹针疗法临床体会.中国针灸,2004,24 (3):201-203.
    [104] 薄智云.谈谈腹针疗法.中国针灸,2001;21(8):474.

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700