望水白×南大2419群体抗赤霉病QTL的初步分析
摘要
由赤霉菌引起的小麦赤霉病是小麦生产的主要病害之一。培育抗病品种是防治赤霉病最安全、有效的措施。然而，抗源匮乏和抗性遗传机制不清严重地限制了小麦抗赤霉病育种的进展。因此，发掘新的抗病基因，并对其进行基因定位是目前小麦赤霉病研究的主要内容之一。分子标记技术的发展和QTL作图方法的不断完善，为深入开展赤霉病抗性遗传分析提供了基础。
望水白是我国江苏的地方品种，为少数几个优异小麦赤霉病抗源之一。开展对望水白抗赤霉病QTL的研究，有助于阐明赤霉病抗性遗传机制，为人们通过育种方法累加不同来源的抗性基因提供理论基础。
本研究构建了望水白×南大2419的F_6代重组自交系群体，并分别在温室和田间对其进行了赤霉病抗性鉴定。利用RAPD和SSR分子标记对该群体株系进行了基因型分析，获得了10个与赤霉病抗性显著相关的标记位点(p＜0.05)，它们分别是Xnau23、Xnau16.3、Xnau16.2、Xnau22、Xnau11.2、Xnau11.1、Xnaul、Xnau14.1、Xnau6.1和Xnau27。其中，分别与病小穗数、病节数和病节长度显著相关的位点有6个、10个和8个。可能由于性状间的相关性，有些标记位点与一个以上的性状相关。Xnau16.3、Xnau16.2、Xnau22和Xnau11.1与病节数和病节长度的相关性在本研究两个试验(温室和田间)间有很好的一致性，以Xnau16.3和Xnau22对病节数和病节长度的效应较大。连锁分析表明，上述与赤霉病
抗性相关的位点分别位于染色体ZB、3A、3B和SB上。
通过区间作图分析，一个QTL被定位于xnau23一Xnau22之间，另一
个被定位于xnaul了.了一xnau24之间，二者的抗性等位基因均来源于抗病
亲本望水白。位于Xnau23一Xnau22之间的效应较大，分别解释了温室试
验中20.1%的病节数变异和15.9%的病节长度变异，及田间试验中n.2%
的病节数变异和11.6%的病节长度变异。还有一个QTL被定位于xnau了一
xnau14.了之间，它解释了田间试验中9.0%的病节数变异。该QTL的抗
性等位基因来源于感病亲本南大2419。
Fusarium head blight (FHB), caused by Fusarium graminearum Schwabe (telomorph: Gibberella zeae), is a major disease of wheat. Outbreak of FHB can result in devastating economic losses to wheat production, since it not only lowers the yield but also deteriorates the quality of wheat grains. Deployment of scab-resistant varieties is the most economical measure in controlling this disease. However, the paucity of germplasms and lack of knowledge about the resistance genetics have greatly limited the progress in scab resistance breeding. To identify genes for scab resistance, a population of F6 recombinant inbred lines (RILs) from a cross 'Wangshuibai'(resistant) x 'Nanda 2419'(susceptible) was produced. The population was evaluated in a greenhouse and a field for FHB resistance through single floret inoculation of the conidia at flowering stage. Mist system was used to maintain the moisture suitable for disease development. Fifteen days after the inoculation, data were
collected for number of diseased spikelets, number of diseased internodes and length of diseased rachis. SSR and RAPD markers were screened for polymorphisms between the parents and between the resistant and susceptible pools. The polymorphic markers were applied in genotyping of the populations. Using one-way ANOVA and regression analysis, ten markers were found to be significantly associated with FHB resistance (p<0.05), including 6 with the number of diseased spikes, 10 with the number of diseased internodes and 8 with the length of diseased rachis. Because of the trait correlation, some of the markers were shared among the three traits. Among the ten markers, four which showed association with the number of diseased internodes and the length of diseased rachis were consentaneous in the greenhouse and field test. These ten markers were mapped to chromosomes 2B, 3A, 3B and 5B, respectively.
By interval analysis, three intervals showed significant association with FHB resistance. Two of them were located between Xnau23 - Xnau22 and between Xnaull. 1 - Xnau24. The resistance alleles of both loci derived from the resistant parent 'Wangshuibai'. The third interval was located between SSR1021 and Xnaul4.1. The resistance allele of this QTL derived from the susceptible parent 'Nanda 2419'. The one between Xnau23 - Xnau22 has the largest effect, explaining 20.1% and 15.9% of the phenotypic variance for the
number of diseased internodes and the length of diseased rachis respectively in the greenhouse test, and 11.2% and 11.6% of the phenotypic variance respectively for these two traits in the field test. The identification of QTLs for scab resistance paves the way for discovery of scab resistance genes and marker-assisted selection of scab resistance.
望水白是我国江苏的地方品种，为少数几个优异小麦赤霉病抗源之一。开展对望水白抗赤霉病QTL的研究，有助于阐明赤霉病抗性遗传机制，为人们通过育种方法累加不同来源的抗性基因提供理论基础。
本研究构建了望水白×南大2419的F_6代重组自交系群体，并分别在温室和田间对其进行了赤霉病抗性鉴定。利用RAPD和SSR分子标记对该群体株系进行了基因型分析，获得了10个与赤霉病抗性显著相关的标记位点(p＜0.05)，它们分别是Xnau23、Xnau16.3、Xnau16.2、Xnau22、Xnau11.2、Xnau11.1、Xnaul、Xnau14.1、Xnau6.1和Xnau27。其中，分别与病小穗数、病节数和病节长度显著相关的位点有6个、10个和8个。可能由于性状间的相关性，有些标记位点与一个以上的性状相关。Xnau16.3、Xnau16.2、Xnau22和Xnau11.1与病节数和病节长度的相关性在本研究两个试验(温室和田间)间有很好的一致性，以Xnau16.3和Xnau22对病节数和病节长度的效应较大。连锁分析表明，上述与赤霉病
抗性相关的位点分别位于染色体ZB、3A、3B和SB上。
通过区间作图分析，一个QTL被定位于xnau23一Xnau22之间，另一
个被定位于xnaul了.了一xnau24之间，二者的抗性等位基因均来源于抗病
亲本望水白。位于Xnau23一Xnau22之间的效应较大，分别解释了温室试
验中20.1%的病节数变异和15.9%的病节长度变异，及田间试验中n.2%
的病节数变异和11.6%的病节长度变异。还有一个QTL被定位于xnau了一
xnau14.了之间，它解释了田间试验中9.0%的病节数变异。该QTL的抗
性等位基因来源于感病亲本南大2419。
Fusarium head blight (FHB), caused by Fusarium graminearum Schwabe (telomorph: Gibberella zeae), is a major disease of wheat. Outbreak of FHB can result in devastating economic losses to wheat production, since it not only lowers the yield but also deteriorates the quality of wheat grains. Deployment of scab-resistant varieties is the most economical measure in controlling this disease. However, the paucity of germplasms and lack of knowledge about the resistance genetics have greatly limited the progress in scab resistance breeding. To identify genes for scab resistance, a population of F6 recombinant inbred lines (RILs) from a cross 'Wangshuibai'(resistant) x 'Nanda 2419'(susceptible) was produced. The population was evaluated in a greenhouse and a field for FHB resistance through single floret inoculation of the conidia at flowering stage. Mist system was used to maintain the moisture suitable for disease development. Fifteen days after the inoculation, data were
collected for number of diseased spikelets, number of diseased internodes and length of diseased rachis. SSR and RAPD markers were screened for polymorphisms between the parents and between the resistant and susceptible pools. The polymorphic markers were applied in genotyping of the populations. Using one-way ANOVA and regression analysis, ten markers were found to be significantly associated with FHB resistance (p<0.05), including 6 with the number of diseased spikes, 10 with the number of diseased internodes and 8 with the length of diseased rachis. Because of the trait correlation, some of the markers were shared among the three traits. Among the ten markers, four which showed association with the number of diseased internodes and the length of diseased rachis were consentaneous in the greenhouse and field test. These ten markers were mapped to chromosomes 2B, 3A, 3B and 5B, respectively.
By interval analysis, three intervals showed significant association with FHB resistance. Two of them were located between Xnau23 - Xnau22 and between Xnaull. 1 - Xnau24. The resistance alleles of both loci derived from the resistant parent 'Wangshuibai'. The third interval was located between SSR1021 and Xnaul4.1. The resistance allele of this QTL derived from the susceptible parent 'Nanda 2419'. The one between Xnau23 - Xnau22 has the largest effect, explaining 20.1% and 15.9% of the phenotypic variance for the
number of diseased internodes and the length of diseased rachis respectively in the greenhouse test, and 11.2% and 11.6% of the phenotypic variance respectively for these two traits in the field test. The identification of QTLs for scab resistance paves the way for discovery of scab resistance genes and marker-assisted selection of scab resistance.
引文
柏贵华，肖庆璞，梅籍芳．六个小麦品种抗赤霉病性的遗传表现．上海农业学报，1989，5(4)：17-23．
柏贵华，周朝飞，钱存鸣，夏穗生，葛永福，陈志德．小麦品种抗赤霉病扩展基因的遗传分析．见：朱立宏主编．主要农作物抗病性遗传研究进展．南京：江苏科技出版社，1990．171-177．
曹永国，王国英，王守才，魏艳玲，卢江，谢友菊，戴景瑞．玉米RFLP遗传图谱的构建及矮生基因定位．科学通报，1999，44(20)：2178-2182．
陈楚和．小麦抗赤霉病遗传研究．浙江农业大学学报，1983，9(2)：115-126．
陈焕玉，张乐庆，潘雪萍，陈伟栋，张林．普通小麦八个品种对赤霉病抗扩展的双列杂交分析．华南农业大学学报，1989，10(4)：56-64．
陈建莉．小麦赤霉病抗源苏麦3号的抗性遗传及育种策略．陕西农业科学，1989，2(12)：2-5．
陈佩度，王兆悌，王苏玲，黄俐，王裕中，刘大钧．将大赖草种质转移给普通小麦的研究．Ⅲ．抗赤霉病异附加系选育．遗传学报，1995，22(3)：206-210．
程顺和，杨士敏，张伯桥，季开桢，赵步洪，高德荣．小麦对赤霉病的抗扩展性鉴定方法的研究．中国农业科学，1994，27(2)：45-49．
郭云忠，段双科，张涛．病情指数划分小麦品种(系)赤霉病抗病性类型方法的改进研究．河南农业大学学报，1999，33(4)：336-338．
蒋国梁，陈兆夏，吴兆苏．小麦抗赤霉病基因库轮回选择效果的初步研究．南京农业大学学报，1991，14(2)：6-11．
金善宝．《中国小麦学》．北京：中国农业出版社，1996．286-287．
李清铣，王彰明．麦类禾谷镰刀菌致病性鉴定．植物保护学报，1982，(3)：163-168．
李又芳，余毓君．七个小麦品种对赤霉病抗扩展性指标的双列杂交分析．华中农业大学学报，1988a，7(1)：7-14．
李又芳，余毓君．小麦品种温州红和尚对赤霉病抗性指标的单体分析，华中农学院学报，1988b，7(4)：327-331．
廖玉才，余毓君．七个小麦品种抗赤霉病性的双列杂交分析．华中农学院学报，1985a，4(3)：1-10．
廖玉才，余毓君．小麦地方品种望水白抗赤霉病性的遗传分析．华中农学
院学报，1985b，4(2)：6-14．
林一波，杨竹平，吴兆苏．不同地理来源抗赤霉病小麦品种的抗性遗传分析．上海农业学报，1992，8(1)：31-36．
刘思衡，巫升鑫，李始明，方毅敏，许文真．小麦抗赤霉病性超亲选育研究．中国农业科学，1998，31(1)：40-45．
刘文轩，陈佩度，刘大钧．一个普通小麦-在赖草易位系T01的选育与鉴定．作物学报，2000，26(3)：305-309．
刘宗镇，汪志远，赵文俊，黄德崇等．我国改良小麦品种抗赤霉病性的来源与抗赤霉病性改良中的问题．中国农业科学，1992，25(4)：49-52．
刘宗镇等．小麦品种资源抗赤霉病性的研究．见：庄巧生，王恒立主编．小麦育种理论与实践的进展．北京：科学普及出版社，1987．196-207．
陆维忠，程顺和，王裕中．小麦赤霉病研究．北京：科学出版社，2001．44
万永芳，颜济，杨俊良，刘法圈．小麦近缘野生植物的赤霉病抗性研究．植物病理学报，1997，27(2)：107-111．
汪杏芬，吴丽芳，陈佩度，刘大钧．普通小麦-鹅观草异附加系的选育与鉴定初报．植物学报，1995，37(11)：878-884．
汪志远．小麦品种抗赤霉病性鉴定和抗赤性改良进展．江苏农业科学，1989，(增刊1)：64-69．
王秀娥，陈佩度，刘大钧．同胞质普通小麦-纤毛鹅观草附加系D和端体异附加系tBL的选育．遗传学报，1997，24(2)：137-140．
王雅平，王进先．小麦品种对赤霉病抗扩展性的遗传研究．吉林农业科学，1991，1：21-28．
王裕中，杨新宁，肖庆璞．小麦赤霉病鉴定技术的改进及其抗源的开拓，中国农业科学，1982，15(5)：67-77．
王裕中．江苏省小麦赤霉病菌优势种—禾谷镰刀菌的致病力．江苏农业学报，1985，(1)：11-16．
翁益群，刘大钧．鹅观草(Roegneria C. Koch)与普通小麦(Triticum aestivum L.)属间杂种 F_1 的形态、赤霉病抗性细胞遗传学研究．中国农业科学，1989，22(5)：1-7．
吴郁文，任树新，刘春光，侯宁，张翠兰，张炎．异源细胞质对小麦赤霉病抗性的效应．科学通报，1998，43(5)：510-514．
向阳海，陆维忠，朱作为，任丽娟，张旭，沈晓蓉．小麦赤霉病抗性的RAPD标记筛选与分析．农业生物技术学报，2001，9(3)：247-250
肖世和．小麦抗赤霉病性的配合力及因子分析．湖南农学院学报，1985，1：9-16．
徐雍皋，方中达．玉蜀黍赤霉病对小麦致病力的测定方法和致病力分化．植物病理学报，1982，2(4)：53-57．
姚金保，葛永福，王书文，姚国才，周朝飞，钱存鸣．小麦品种苏麦3号抗赤霉病基因的染色体定位研究．作物学报，1997，23(4)：450-453．
余华．小麦抗赤霉病鉴定技术及其育种中的应用．麦类作物，1997，17(3)：22-24．
余毓君，廖玉才．小麦品种对赤霉病抗扩展类型抗性组分的探索分析．作物学报，1988，14(3)：194-201．
余毓君．平湖剑子麦，洪湖大太宝，崇阳红麦，延岗坊主，万年2号赤霉病性基因分析．作物学报，1991，17(4)：248-254．
余毓君．小麦品种苏麦3号抗赤霉病性及产量因素的单体分析．华中农学院学报，1982，(2)：70-72．
袁建华．利用杀配子染色体创造大赖草易位系(博士论文)，南京：南京农业大学，1999．34-72．
张乐庆，潘雪萍．小麦品种对赤霉病抗扩展的遗传研究．华南农学院学报，1982，3(4)：21-29．
赵忠贞，闵捷．小麦品种抗赤霉病遗传特性的初步观察．浙江农业科学，1980，(6)：286-287．
邹明烈，柏贵华，赵寅槐，王苏．小麦品种不同株高等基因系赤霉病性比较．江苏农业学报，1988，4(1)：1-5．
左开井，孙济中，张献龙，聂以春，刘金兰，冯纯大．利用RFLP、SSR和RAPD标记构建陆地棉分子标记连锁图．华中农业大学学报，2000，19(3)：190-193．
Alpert KB, Tanksley SD (1996) High-resolution mapping and isolation of a yeast artificial chromosome contig containing fw2.2: A major fruit weight quantitative trait locus in tomato. Proc Natl Acad Sci USA 93:15503-15507
Anderson JA, Stack RW, Liu S, Waldron BL, Fjeld AD, Coyne C, Moreno-Sevilla B, Fetch MJ, Song QJ, Cregan PB, Frohberg RC (2001) DNA markers for Fusarium head blight resistance QTLs in two wheat populations. Theor Appl Genet 102:1164-1168
Anderson JA, Waldron BL, Moreno-Sevilla B, Stack RW, Frohberg RC (1998) DNA markers for Fusarium head blight resistance QTL in two wheat populations. National Fusarium Head Blight Forum, 26-27 Oct 1998, Michigan, pp 57-59
Arthur JC (1891) Wheat scab. Ind Agric Exp Sta Bull 36:129-132 (cited after Mesterhazy 1995)
Bai G, Kolb FL, Shaner G, Domier LL (1999) Amplified fragment length polymorphism markers linked to a major quantitative trait locus controlling scab resistance in wheat. Phytopathology 89:343-348
Bai GH, Guo PG, Kolb FL (2001) Genetic diversity in scab-resistant wheat cultivars based on molecular markers. National Fusarium Head Blight Forum, 8-10 Dec 2001, Cincinnati, pp7
Bai GH, Shaner G, Ohm H (2000) Imheritance of resistance to Fusarium graminearum in wheat. Theor Appl Genet 100:1-8
Ban T (1997) Genetic analysis of Fusarium head blight in resistance using wheat doubled haploids. In: Fusarium head scab: global status and future prospects (Dubin HJ, Gilchrist L, Reeves J, and McNab A eds). CIMMYT, Mexico DF pp 71-78
Ban T (2000) Analysis of Quantitative Trait Loci associated with resistance to Fusarium head blight caused by Fusarium graminearum Schwabe and of resistance mechanisms in wheat (Triticum aestivum L.). Breeding Science 50:131-137
Ban T, Suenaga K (2000) Genetic analysis of resistance to Fusarium head blight caused by Fusarium graminearum in Chinese wheat cultivar Sumai 3 and the Japanese cultivar Saikai 165. Euphytica 113:87-99
Beavis WD, Lee M, Grant D, Hallauer AR, Owens T, Katt M, Blair D (1992) The influence of random mating on recombination among RFLP loci. Maize Genet Coop News 66:52-53
Bernacchi D, Beck-Bunn T, Emmatty D, Eshed Y, Inai S, Lopez J, Petiard V, Sayama H, Uhlig J, Zamir D, Tanksley SD (1998) Advanced backcross QTL analysis of tomato. Ⅱ. Evaluation of near-isogenic lines carrying single-donor introgressions for desirable wild QTL-alleles derived from Lycopersicon hirsutum and L. pimpinellifolium. Theor Appl Genet 97 (1/2): 170-180
Bernacchi D, Beck-Bunn T, Eshed Y, Lopez J, Petiard V, Uhlig J, Zamir D, Tanksley SD (1998) Advanced backcross QTL analysis in tomato. Ⅰ.
Identification of QTLs for traits of agronomic importance from Lycopersicon hirsutum. Theor Appl Genet 97(3):381-397
Botstein D, White RL, Skolnick M, Davis RW (1980) Construction of genetic linkage map in man using restriction fragment length polymorphisms. Am J Hum Genet 32:314-331
Bourdoncle W, Ohm HW (2002) Identification of DNA markers for Fusarium head blight resistance of wheat line Huapei 57-2 In: National Fusarium Head Blight Forum Proceedings, 7-9 Dec 2002, Cincinnati, pp 229
Bowen DE, Liu S, Dill-Macky R, Evans CK, Anderson JA (2002) Mapping Fusarium head blight resistance QTL in the Chinese wheat line Fujian 5114. In: National Fusarium Head Blight Forum Proceedings, 7-9 Dec 2002, Cincinnati, pp 21
Buerstmayr H, Lemmens M, Fedak G, Ruckenbauer P (1999) Back-cross reciprocal monosomic analysis of Fusarium head blight resistance in wheat (Triticum aestivum L.). Theor Appl Genet 98:76-85
Buerstmayr H, Lemmens M, Grausgruber H, Ruckenbauer P (1996a) Scab resistance of international wheat germplasm. Cereal Res Commun 24:195-202
Buerstmayr H, Lemmens M, Hartl L, Doldi L, Steiner B, Stierschneider M, Ruckenbauer P (2002) Molecular mapping of QTLs for Fusarium head blight resistance in spring wheat. Ⅰ. Resistance to fungal spread (Type Ⅱ resistance). Theor Appl Genet 104:84-91
Buerstmayr H, Lemmens M, Patschka G, Grausgruber H, Ruckenbauer P (1996b) Head blight (Fusarium spp.) resistance of wheat cultivars registered in Austria. Die Bodenkultur 47:183-190
Buerstmayr H, Steiner B, Lemmens M, Ruckenbauer P (2000) Resistance to Fusarium head blight in two winter wheat crosses: heritability and trait associations. Crop Sci 40:1012-1018
Chao S, Sharp PJ, Worland AJ, Warham EJ, Koebner RMD, Gale MD (1989) RFLP-based genetic maps of wheat homoeologous group 7 chromosomes, Theor Appl Genet 78:495-504
Chen J, Griffey CA, Saghai-Maroof MA, Zhao W, Xie W, Pridgen T, Biyashev RM (2000) Genetic analysis of resistance to Fusarium head blight in common wheat. National Fusarium Head Blight Forum, 10-12 Dec 2000, Cincinnati, pp 19-24
de Vicente MC, Tanksley SD (1993) QTL analysis of transgressive segregation in an interspecific tomato cross. Genetics 134:585-596
Delaney DE, Nasuda S, Endo TR, Gill BS, Hulberty SH (1995) Cytologically based physical maps of the group 2 chromosomes of wheat. Theor Appl Genet 91:568-573
Dorweiler JE, Stec A, Kermicle J, Doebley JF (1993) Teosinte glume architecture-1-a genetic locus controlling a key step in maize evolution. Science 262:233-235
Dunford RP, Kurata N, Laurie DA, Money TA, Minobe Y, Moore G (1995) Conservation of fine-scale DNA marker order in the genomes of rice and the Triticeae. Nucleic Acids Reserach 23:2724-2728
Edwards M, Stuber CW, Wendel JF (1987) Molecular-marker-facilitated investigations of quantitative trait loci in maize. Ⅰ. Numbers, genomic distribution, and types of gene action. Genetics 116:113-125
Eshed Y, Zamir D 1995 An introgression line population of Lycopersicon pennellii in the cultivated tomato enables the identification and fine mapping of yield-associated QTL. Genetics 141:1147-1162
Frary A, Nesbitt TC, Grandillo S, Knaap E, Cong B, Liu J, Meller J, Elber R, Alpert KB, Tanksley SD (2000)fw2.2: A quantitative trait locus key to the evolution of tomato fruit size. Science 289 (5476):85-88
Fridman E, Pleban T, Zamir D (2000) A recombination hotspot delimits a wild-species quantitative trait locus for tomato sugar content to 484bp within an invertase gene. Proc Natl Acad Sci USA 97:4718-4723
Fulton TM, Beck-Bunn T, Emmatty D, Eshed Y, Lopez J, Uhlig J, Zamir D, Tanksley SD (1997) QTL analysis of an advanced backcross of Lycopersicon peruvianum to the cultivated tomato and comparison of QTLs found in other wild species. Theor Appl Genet 95:881-894
Gervais L, Dedryver F, Morlais JY, Bodusseau V, Negre S, Bilous M, Groos C, Trottet M (2003) Mapping of quantitative trait loci for field resistance to Fusarium head blight in an European winter wheat. Theor Appl Genet 106:961-970
Giovannoni JJ, Wing RA, Ganal MW, Tanksley SD (1991) Isolation of molecular markers from specific chromosome intervals using DNA pools from existing populations. Nucl Acids Res 19(23):6553-6558
Gocho H, et al. (1983) Induced mutations and genetic correlations between scab reticesistance and some agronomics characters in wheat. Proc. 6th Intern. Wheat Gren Symp, Kyoto. pp 801-805
Grausgruber H, Lemmens M, Bürstmayr H, Ruckenbauer P (1998) Chromosomal location of Fusarium head blight resistance and in vitro toxin tolerance in wheat using the Hobbit'sib'(Triticum macha) chromosome substitution lines. J Genet Breed 52:173-180
Grodzickev T, Williams J, Sharp P, Sambrook J (1974) Cold Spring Harb. Symp. 39:439
Gupta A, Lipps PE, Campbell KG (2000) Finding quantitative trait locus associated with Fusarium head blight of wheat using simple sequence repeat markers. National Fusarium Head Blight Forum, 10-12 Dec 2000, Cincinnati, pp 28-32
Hanson EW, Ausemus ER, Stakman EC (1950) Varietal resistance of spring wheats to fusarial head blight. Phytopathology 40:902-914
Harushima Y, Yano M, Shomura A, Sato M, Shimano T, Kuboki Y, Yamamoto T, Lin SY, Antonio BA, Parco A, Kajiya H, Huang N, Yamamoto K, Nagamura Y, Kurata N, Khush GS, Sasaki T (1998) A high-density rice genetic linkage map with 2275 markers using, a single F2 population. Genetics 148:479-494
Helentjaris T, Slocum M, Wright S, et al. (1986) Construction of genetic linkage maps in maize and tomato using restriction fragment length polymorphisms. Theor Appl Genet 72:761-769
Huang XQ, Cster, H Ganal MW, Rder MS (2003) Advanced backcross QTL analysis for the identification of quantitative trait loci alleles from wild relatives of wheat (Triticum aestivum L.). Theor Appl Genet 106:1379-1389
Ittu M, Saulescu NN, Hagima I, Ittu G, Mustatea P (2000) Association of Fusarium head blight resistance with gliadin loci in a winter wheat cross. Crop Sci 40:62-67
Kojima S, Takahashi Y, Kobayashi Y, Monna L, Sasaki T, Araki T, Yano M (2002) Hd3a, a rice ortholog of the arabidopsis FT gene, promotes transition to flowering downstream of Hdl under short-day conditions. Plant Cell Physiol 43 (10):1096-1105.
Kolb FL, Bai GH, Muehlbauer GJ, Anderson JA, Smith KP, Fedak G(2001) Host plant resistance genes for Fusarium head blight: mapping and manipulation with molecular markers. Crop Sci 41:611-619
Lander ES, Botstein D (1989) Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 121:185-199
Lee M (1995) DNA markers and plant breeding program. Advance in Agronomy 55:265-344
Luo ZW, Wu CI, Kearsey MJ (2002) Precision and high-resolution mapping of quantitative trait loci by use of recurrent selection, backcross or intercross schemes. Genetics 161 (2):915-929
Ma ZQ, Rder MS, Sorrells ME (1996) Frequencies and sequence characteristics of di-, tri-, tetra-nucleotide microsatellites in wheat. Genome 39:123-130
Ma ZQ, Sorrells ME (1995) Genetic analysis of fertility restoration in wheat using restriction fragment length polymorphisms. Crop Sci 35:1137-1143
Ma ZQ, Sorrells ME (1995) Genetic analysis of fertility restoration in wheat using restriction fragment length polymorphisms. Crop Sci 35:1137-1143
Ma ZQ, Steffenson BJ, Prom LK, Lapitan NLV (2000) Mapping of quantitative trait loci for Fusarium head blight resistance in six-rowed barley. Phytopathology 90:1079-1088
McCouch SR, Kochert G, Yu ZH, Wang ZY, Khush GS, Coffman WR, Tanksley SD (1988) Molecular mapping of rice chromosomes. Theor Appl Genet 76:815-829
Mesterhazy A (1977) Reaction of winter wheat varieties to four Fusarium species. Phytopathologische Zeitschrift 90 (2):104-112
Mesterhazy A (1983) Breeding wheat for resistance to Fusarium graminearum and Fusarium culmorum. Pflanzenzücht 91:295-311
Mesterhazy A (1995) Types and components of resistance to Fusarium head blight. Plant Breed 114:377-386
Michelmore RW, Paran I, Kesseli RV (1991) Identification of markers linked to disease-resistance genes by bulked segregant analysis: A rapid method to detect markers in specific genomic regions by using segregating populations. Proc Natl Acad Sci USA 88:9828-9832
Mielke H (1988) Studies into Fusarium culmorum (W. G. Sm.) Sacc. as the causal agent of foot and head diseases in wheat. Mitteilungen aus der Biologischen Bundesanstalt fuer Land und Forstwirtschaff Berlin Dahlem 238:100-101
Miller JD, Young JC, Sampson DR (1985) Deoxynivalenol and Fusarium head blight resistance in spring cereals. Phytopathol 113:359-367
Nakagawa MO (1955) Studies on ear-scab resistance of wheat plants 2.Genetical factors affecting the inheritance on ear-scab disease of wheat plants. (in Japanese with English summary.) Japan J. Breeding 5:15-22
Otto CD, Kianian SF, Elias EM, Stack RW, Joppa LR (2002) Genetic sissection of a major Fusarium head blight QTL in tetraploid wheat. Plant Mol Biol 48 (5-6):625-632
Paterson AH, DeVema JW, Lanini B, Tanksley SD (1990) Fine mapping of quantitative trait loci using selected overlapping recombinant chromosomes, in a interspecific cross tomato. Genetics 124:735-742
Paterson AH, Lander ES, Hewitt JD, Peterson S, Lincoln SE, Tanksley SD (1988) Resolution of quantitative traits into Mendelian factors using a complete linkage map of restriction fragment length polymorphisms. Nature (London) 335: 721-726
Rder MS, Korzun V, Wendehake K, Plaschke J, Tixier MH, Leroy P, Ganal MW (1998) A microsatellite map of wheat. Genetics 149:2007-2023
Rder MS, Korzun V, Wendehake K, Plaschke J, Tixier MH, Leroy P, Ganal MW (1998). A microsatellite map of wheat. Genetics 149:2007-2023
Saur L (1991) Source of resistance to head blight caused by Fusarium culmorum in bread wheat and related species [Triticeae]. Agronomic 11 (7):535-541.
Sax K (1923) The association of size differences with seed-coat pattern and pigmentation in Phaseolus vulgaris. Genetics 8:552-560
Schroeder HW, Christensen JJ (1963) Factors affecting the resistance of wheat to scab caused by Gibberella zeae. Phytopathology 53:831-838
Shen XR, Ittu M, Ohm H (2003a) Quantitative trait locus conditioning resistance to Fusarium head blight in wheat line F201R. Crop Sci. 43:850-857
Shen XR, Zhou M, Lu W, Ohm H (2003b) Detection of Fusarium head blight resistance QTL in a wheat population using bulked segregant analysis. Theor Appl Genet 106:1041-1047
Singh RP, Ma H, Rajaram S (1995) Genetic analysis of resistance to scab in spring wheat cultivar Frontana. Plant Dis 79 (3):238-240
Snijders CHA (1990) Genetic variation for resistance to Fusarium head blight in bread wheat. Euphytica 50:171-179
Snijders CHA, Krechting CF (1993) Inhibition of deoxynivalenol translocation and fungal colonization in Fusarium head blight resistant wheat. Jacobs T 1993:348
Soller M, Brody T, Genizi A (1976) On the power of experimental designs for the detection of linkage between marker loci and quantitative loci in crosses between inbred lines. Theor Appl Genet 47:35-39
Stack RW, Elias EM, Mitchell-Fetch J, Miller JD, Joppa LR (2002) Fusarium head blight reaction of langdon durum-triticum dicoccoides chromosome substitution lines. Crop Sci 42:637-642
Stack RW, Frohberg RC, Casper H (1997) Reaction of spring wheats incorporating Sumai#3-derived resistance to inoculation with seven Fusarium species. Cereal Res Commun 25:667-671
Stack RW, Miller JD, Joppa LR (2002b) Proposed chromosomal location of FHB resistance genes in additional sets of durum disomic substitution lines derived from different T. dicoccoides accessions. In: National Fusarium Head Blight Forum Proceedings, 7-9 Dec 2002, Cincinnati, pp 217
Stuber CW, Edwards M, Wendel JF (1987) Molecular-marker-facilitated investigations of quantitative trait loci in maize. 2. Factors influencing yield and its component traits. Crop Sci 27:639-648
Takahashi Y, Shomura A, Sasaki T, Yano M (2001) Hd6, a rice quantitative trait locus involved in photoperiod sensitivity, encodes the alpha subunit of protein kinase CK2. Proc Natl Acad Sci USA 98 (14):7922-7927.
Tanksley SD (1993) Mapping polygenes. Annu Rev Genet. 27:205-233
Tanksley SD, Medino-Filho H, Rick CM (1982) Use of naturally occuring enzyme variation to detect and map genes controlling quantitative traits in an interspecific backcross of tomato. Heredity 49:11-25
Tanksley SD, Nelson JC (1996) Advanced backcross QTL analysis: a method for the simultaneous discovery and transfer of valuable QTLs from unadapted germplasm into elite breeding lines. Theor Appl Genet 92:191-203
Van Eeuwijk FA, Mesterhazy A, Kling CI, Ruckenbauer P, Saur L, Buerstmayr H, Lemmens M, Keizer LCP, Maurin N, Snijders CHA (1995) Assessing non-specificity of resistance of wheat to head blight caused by inoculation with European strains of Fusarium culmorum, F. graminearum and F. nivale, using a multiplicative model for interaction. Theor Appl Genet 90:221-228
Waldron BL, Moreno-Sevilla B, Anderson JA, Stack RW, Frohberg RC (1999) RFLP mapping of QTL for Fusarium head blight resistance in wheat. Crop Sci 39:805-811
Weller JI (1986) Maximum likelihood techniques for the mapping and analysis of quantitative trait loci with the aid of genetic marker. Biometrics 42:627-640
Xiao JH, Li J, Grandillo S, Ahn SN, Yuan L, Tanksley SD, McCouch SR (1998) Identification of trait-improving quantitative trait loci alleles from a wild rice relative, Oryza rufipogon. Genetics 150:899-909
Xu DH, Juan HF, Nohda M, Ban T (2001) QTLs mapping of type Ⅰ and type Ⅱ resistance to FHB in wheat. In: National Fusarium Head Blight Forum Proceedings, 10-12 Dec 2001, Cincinnati, pp 40-42
Yamamoto T, Lin SY, Antonio BA, Parco A, Kajiya H, Huang N, Yamamoto K, Nagamura Y, Kurata N, Khush GS, Sasaki T (1998) A high-density rice genetic linkage map with 2275 markers using a single F_2 population. Genetics 148:479-494
Yano M, Katayose Y, Ashikari M, Yamanouchi U, Monna L, Fuse T, Baba T, Yamamoto K, Umehara Y, Nagamura Y, Sasaki T (2000) Hdl, a major photoperiod sensitivity quantitative trait locus in rice, is closely related to the arabidopsis flowering time gene CONSTANS. Plant Cell 12:2473-2484
Zeng ZB (1994) Precision mapping of quantitative trait loci. Genetics 136:1457-1468
Zhou WC, Kolb FL, Bai G, Shaner G, Domier LL (2002) Genetic analysis of scab resistance QTL in wheat with microsatellite and AFLP markers. Genome 45 (4):719-727
Zhou WC, Kolb FL, Bai GH, Shaner G, Domier LL (2000) SSR mapping and sub-arm physical location of a major scab resistance QTL in wheat. In: National Fusarium Head Blight Forum Proceedings, 10-12 Dec 2000, Cincinnati, pp 69-72
Zhu Z, Ren L, Xiang Y, Shen X, Zhang X, Zhou M, Lu W (2000) Identification of RAPD markers linked to scab resistance in the wheat Sumai 3. In: Raupp J, Ma Z, Chen P, Liu D (eds) Proc Int Symp on Wheat Improvement for Scab Resistance. 5-11 May, 2000, Suzhou and Nanjing, China, pp 132-135
柏贵华，周朝飞，钱存鸣，夏穗生，葛永福，陈志德．小麦品种抗赤霉病扩展基因的遗传分析．见：朱立宏主编．主要农作物抗病性遗传研究进展．南京：江苏科技出版社，1990．171-177．
曹永国，王国英，王守才，魏艳玲，卢江，谢友菊，戴景瑞．玉米RFLP遗传图谱的构建及矮生基因定位．科学通报，1999，44(20)：2178-2182．
陈楚和．小麦抗赤霉病遗传研究．浙江农业大学学报，1983，9(2)：115-126．
陈焕玉，张乐庆，潘雪萍，陈伟栋，张林．普通小麦八个品种对赤霉病抗扩展的双列杂交分析．华南农业大学学报，1989，10(4)：56-64．
陈建莉．小麦赤霉病抗源苏麦3号的抗性遗传及育种策略．陕西农业科学，1989，2(12)：2-5．
陈佩度，王兆悌，王苏玲，黄俐，王裕中，刘大钧．将大赖草种质转移给普通小麦的研究．Ⅲ．抗赤霉病异附加系选育．遗传学报，1995，22(3)：206-210．
程顺和，杨士敏，张伯桥，季开桢，赵步洪，高德荣．小麦对赤霉病的抗扩展性鉴定方法的研究．中国农业科学，1994，27(2)：45-49．
郭云忠，段双科，张涛．病情指数划分小麦品种(系)赤霉病抗病性类型方法的改进研究．河南农业大学学报，1999，33(4)：336-338．
蒋国梁，陈兆夏，吴兆苏．小麦抗赤霉病基因库轮回选择效果的初步研究．南京农业大学学报，1991，14(2)：6-11．
金善宝．《中国小麦学》．北京：中国农业出版社，1996．286-287．
李清铣，王彰明．麦类禾谷镰刀菌致病性鉴定．植物保护学报，1982，(3)：163-168．
李又芳，余毓君．七个小麦品种对赤霉病抗扩展性指标的双列杂交分析．华中农业大学学报，1988a，7(1)：7-14．
李又芳，余毓君．小麦品种温州红和尚对赤霉病抗性指标的单体分析，华中农学院学报，1988b，7(4)：327-331．
廖玉才，余毓君．七个小麦品种抗赤霉病性的双列杂交分析．华中农学院学报，1985a，4(3)：1-10．
廖玉才，余毓君．小麦地方品种望水白抗赤霉病性的遗传分析．华中农学
院学报，1985b，4(2)：6-14．
林一波，杨竹平，吴兆苏．不同地理来源抗赤霉病小麦品种的抗性遗传分析．上海农业学报，1992，8(1)：31-36．
刘思衡，巫升鑫，李始明，方毅敏，许文真．小麦抗赤霉病性超亲选育研究．中国农业科学，1998，31(1)：40-45．
刘文轩，陈佩度，刘大钧．一个普通小麦-在赖草易位系T01的选育与鉴定．作物学报，2000，26(3)：305-309．
刘宗镇，汪志远，赵文俊，黄德崇等．我国改良小麦品种抗赤霉病性的来源与抗赤霉病性改良中的问题．中国农业科学，1992，25(4)：49-52．
刘宗镇等．小麦品种资源抗赤霉病性的研究．见：庄巧生，王恒立主编．小麦育种理论与实践的进展．北京：科学普及出版社，1987．196-207．
陆维忠，程顺和，王裕中．小麦赤霉病研究．北京：科学出版社，2001．44
万永芳，颜济，杨俊良，刘法圈．小麦近缘野生植物的赤霉病抗性研究．植物病理学报，1997，27(2)：107-111．
汪杏芬，吴丽芳，陈佩度，刘大钧．普通小麦-鹅观草异附加系的选育与鉴定初报．植物学报，1995，37(11)：878-884．
汪志远．小麦品种抗赤霉病性鉴定和抗赤性改良进展．江苏农业科学，1989，(增刊1)：64-69．
王秀娥，陈佩度，刘大钧．同胞质普通小麦-纤毛鹅观草附加系D和端体异附加系tBL的选育．遗传学报，1997，24(2)：137-140．
王雅平，王进先．小麦品种对赤霉病抗扩展性的遗传研究．吉林农业科学，1991，1：21-28．
王裕中，杨新宁，肖庆璞．小麦赤霉病鉴定技术的改进及其抗源的开拓，中国农业科学，1982，15(5)：67-77．
王裕中．江苏省小麦赤霉病菌优势种—禾谷镰刀菌的致病力．江苏农业学报，1985，(1)：11-16．
翁益群，刘大钧．鹅观草(Roegneria C. Koch)与普通小麦(Triticum aestivum L.)属间杂种 F_1 的形态、赤霉病抗性细胞遗传学研究．中国农业科学，1989，22(5)：1-7．
吴郁文，任树新，刘春光，侯宁，张翠兰，张炎．异源细胞质对小麦赤霉病抗性的效应．科学通报，1998，43(5)：510-514．
向阳海，陆维忠，朱作为，任丽娟，张旭，沈晓蓉．小麦赤霉病抗性的RAPD标记筛选与分析．农业生物技术学报，2001，9(3)：247-250
肖世和．小麦抗赤霉病性的配合力及因子分析．湖南农学院学报，1985，1：9-16．
徐雍皋，方中达．玉蜀黍赤霉病对小麦致病力的测定方法和致病力分化．植物病理学报，1982，2(4)：53-57．
姚金保，葛永福，王书文，姚国才，周朝飞，钱存鸣．小麦品种苏麦3号抗赤霉病基因的染色体定位研究．作物学报，1997，23(4)：450-453．
余华．小麦抗赤霉病鉴定技术及其育种中的应用．麦类作物，1997，17(3)：22-24．
余毓君，廖玉才．小麦品种对赤霉病抗扩展类型抗性组分的探索分析．作物学报，1988，14(3)：194-201．
余毓君．平湖剑子麦，洪湖大太宝，崇阳红麦，延岗坊主，万年2号赤霉病性基因分析．作物学报，1991，17(4)：248-254．
余毓君．小麦品种苏麦3号抗赤霉病性及产量因素的单体分析．华中农学院学报，1982，(2)：70-72．
袁建华．利用杀配子染色体创造大赖草易位系(博士论文)，南京：南京农业大学，1999．34-72．
张乐庆，潘雪萍．小麦品种对赤霉病抗扩展的遗传研究．华南农学院学报，1982，3(4)：21-29．
赵忠贞，闵捷．小麦品种抗赤霉病遗传特性的初步观察．浙江农业科学，1980，(6)：286-287．
邹明烈，柏贵华，赵寅槐，王苏．小麦品种不同株高等基因系赤霉病性比较．江苏农业学报，1988，4(1)：1-5．
左开井，孙济中，张献龙，聂以春，刘金兰，冯纯大．利用RFLP、SSR和RAPD标记构建陆地棉分子标记连锁图．华中农业大学学报，2000，19(3)：190-193．
Alpert KB, Tanksley SD (1996) High-resolution mapping and isolation of a yeast artificial chromosome contig containing fw2.2: A major fruit weight quantitative trait locus in tomato. Proc Natl Acad Sci USA 93:15503-15507
Anderson JA, Stack RW, Liu S, Waldron BL, Fjeld AD, Coyne C, Moreno-Sevilla B, Fetch MJ, Song QJ, Cregan PB, Frohberg RC (2001) DNA markers for Fusarium head blight resistance QTLs in two wheat populations. Theor Appl Genet 102:1164-1168
Anderson JA, Waldron BL, Moreno-Sevilla B, Stack RW, Frohberg RC (1998) DNA markers for Fusarium head blight resistance QTL in two wheat populations. National Fusarium Head Blight Forum, 26-27 Oct 1998, Michigan, pp 57-59
Arthur JC (1891) Wheat scab. Ind Agric Exp Sta Bull 36:129-132 (cited after Mesterhazy 1995)
Bai G, Kolb FL, Shaner G, Domier LL (1999) Amplified fragment length polymorphism markers linked to a major quantitative trait locus controlling scab resistance in wheat. Phytopathology 89:343-348
Bai GH, Guo PG, Kolb FL (2001) Genetic diversity in scab-resistant wheat cultivars based on molecular markers. National Fusarium Head Blight Forum, 8-10 Dec 2001, Cincinnati, pp7
Bai GH, Shaner G, Ohm H (2000) Imheritance of resistance to Fusarium graminearum in wheat. Theor Appl Genet 100:1-8
Ban T (1997) Genetic analysis of Fusarium head blight in resistance using wheat doubled haploids. In: Fusarium head scab: global status and future prospects (Dubin HJ, Gilchrist L, Reeves J, and McNab A eds). CIMMYT, Mexico DF pp 71-78
Ban T (2000) Analysis of Quantitative Trait Loci associated with resistance to Fusarium head blight caused by Fusarium graminearum Schwabe and of resistance mechanisms in wheat (Triticum aestivum L.). Breeding Science 50:131-137
Ban T, Suenaga K (2000) Genetic analysis of resistance to Fusarium head blight caused by Fusarium graminearum in Chinese wheat cultivar Sumai 3 and the Japanese cultivar Saikai 165. Euphytica 113:87-99
Beavis WD, Lee M, Grant D, Hallauer AR, Owens T, Katt M, Blair D (1992) The influence of random mating on recombination among RFLP loci. Maize Genet Coop News 66:52-53
Bernacchi D, Beck-Bunn T, Emmatty D, Eshed Y, Inai S, Lopez J, Petiard V, Sayama H, Uhlig J, Zamir D, Tanksley SD (1998) Advanced backcross QTL analysis of tomato. Ⅱ. Evaluation of near-isogenic lines carrying single-donor introgressions for desirable wild QTL-alleles derived from Lycopersicon hirsutum and L. pimpinellifolium. Theor Appl Genet 97 (1/2): 170-180
Bernacchi D, Beck-Bunn T, Eshed Y, Lopez J, Petiard V, Uhlig J, Zamir D, Tanksley SD (1998) Advanced backcross QTL analysis in tomato. Ⅰ.
Identification of QTLs for traits of agronomic importance from Lycopersicon hirsutum. Theor Appl Genet 97(3):381-397
Botstein D, White RL, Skolnick M, Davis RW (1980) Construction of genetic linkage map in man using restriction fragment length polymorphisms. Am J Hum Genet 32:314-331
Bourdoncle W, Ohm HW (2002) Identification of DNA markers for Fusarium head blight resistance of wheat line Huapei 57-2 In: National Fusarium Head Blight Forum Proceedings, 7-9 Dec 2002, Cincinnati, pp 229
Bowen DE, Liu S, Dill-Macky R, Evans CK, Anderson JA (2002) Mapping Fusarium head blight resistance QTL in the Chinese wheat line Fujian 5114. In: National Fusarium Head Blight Forum Proceedings, 7-9 Dec 2002, Cincinnati, pp 21
Buerstmayr H, Lemmens M, Fedak G, Ruckenbauer P (1999) Back-cross reciprocal monosomic analysis of Fusarium head blight resistance in wheat (Triticum aestivum L.). Theor Appl Genet 98:76-85
Buerstmayr H, Lemmens M, Grausgruber H, Ruckenbauer P (1996a) Scab resistance of international wheat germplasm. Cereal Res Commun 24:195-202
Buerstmayr H, Lemmens M, Hartl L, Doldi L, Steiner B, Stierschneider M, Ruckenbauer P (2002) Molecular mapping of QTLs for Fusarium head blight resistance in spring wheat. Ⅰ. Resistance to fungal spread (Type Ⅱ resistance). Theor Appl Genet 104:84-91
Buerstmayr H, Lemmens M, Patschka G, Grausgruber H, Ruckenbauer P (1996b) Head blight (Fusarium spp.) resistance of wheat cultivars registered in Austria. Die Bodenkultur 47:183-190
Buerstmayr H, Steiner B, Lemmens M, Ruckenbauer P (2000) Resistance to Fusarium head blight in two winter wheat crosses: heritability and trait associations. Crop Sci 40:1012-1018
Chao S, Sharp PJ, Worland AJ, Warham EJ, Koebner RMD, Gale MD (1989) RFLP-based genetic maps of wheat homoeologous group 7 chromosomes, Theor Appl Genet 78:495-504
Chen J, Griffey CA, Saghai-Maroof MA, Zhao W, Xie W, Pridgen T, Biyashev RM (2000) Genetic analysis of resistance to Fusarium head blight in common wheat. National Fusarium Head Blight Forum, 10-12 Dec 2000, Cincinnati, pp 19-24
de Vicente MC, Tanksley SD (1993) QTL analysis of transgressive segregation in an interspecific tomato cross. Genetics 134:585-596
Delaney DE, Nasuda S, Endo TR, Gill BS, Hulberty SH (1995) Cytologically based physical maps of the group 2 chromosomes of wheat. Theor Appl Genet 91:568-573
Dorweiler JE, Stec A, Kermicle J, Doebley JF (1993) Teosinte glume architecture-1-a genetic locus controlling a key step in maize evolution. Science 262:233-235
Dunford RP, Kurata N, Laurie DA, Money TA, Minobe Y, Moore G (1995) Conservation of fine-scale DNA marker order in the genomes of rice and the Triticeae. Nucleic Acids Reserach 23:2724-2728
Edwards M, Stuber CW, Wendel JF (1987) Molecular-marker-facilitated investigations of quantitative trait loci in maize. Ⅰ. Numbers, genomic distribution, and types of gene action. Genetics 116:113-125
Eshed Y, Zamir D 1995 An introgression line population of Lycopersicon pennellii in the cultivated tomato enables the identification and fine mapping of yield-associated QTL. Genetics 141:1147-1162
Frary A, Nesbitt TC, Grandillo S, Knaap E, Cong B, Liu J, Meller J, Elber R, Alpert KB, Tanksley SD (2000)fw2.2: A quantitative trait locus key to the evolution of tomato fruit size. Science 289 (5476):85-88
Fridman E, Pleban T, Zamir D (2000) A recombination hotspot delimits a wild-species quantitative trait locus for tomato sugar content to 484bp within an invertase gene. Proc Natl Acad Sci USA 97:4718-4723
Fulton TM, Beck-Bunn T, Emmatty D, Eshed Y, Lopez J, Uhlig J, Zamir D, Tanksley SD (1997) QTL analysis of an advanced backcross of Lycopersicon peruvianum to the cultivated tomato and comparison of QTLs found in other wild species. Theor Appl Genet 95:881-894
Gervais L, Dedryver F, Morlais JY, Bodusseau V, Negre S, Bilous M, Groos C, Trottet M (2003) Mapping of quantitative trait loci for field resistance to Fusarium head blight in an European winter wheat. Theor Appl Genet 106:961-970
Giovannoni JJ, Wing RA, Ganal MW, Tanksley SD (1991) Isolation of molecular markers from specific chromosome intervals using DNA pools from existing populations. Nucl Acids Res 19(23):6553-6558
Gocho H, et al. (1983) Induced mutations and genetic correlations between scab reticesistance and some agronomics characters in wheat. Proc. 6th Intern. Wheat Gren Symp, Kyoto. pp 801-805
Grausgruber H, Lemmens M, Bürstmayr H, Ruckenbauer P (1998) Chromosomal location of Fusarium head blight resistance and in vitro toxin tolerance in wheat using the Hobbit'sib'(Triticum macha) chromosome substitution lines. J Genet Breed 52:173-180
Grodzickev T, Williams J, Sharp P, Sambrook J (1974) Cold Spring Harb. Symp. 39:439
Gupta A, Lipps PE, Campbell KG (2000) Finding quantitative trait locus associated with Fusarium head blight of wheat using simple sequence repeat markers. National Fusarium Head Blight Forum, 10-12 Dec 2000, Cincinnati, pp 28-32
Hanson EW, Ausemus ER, Stakman EC (1950) Varietal resistance of spring wheats to fusarial head blight. Phytopathology 40:902-914
Harushima Y, Yano M, Shomura A, Sato M, Shimano T, Kuboki Y, Yamamoto T, Lin SY, Antonio BA, Parco A, Kajiya H, Huang N, Yamamoto K, Nagamura Y, Kurata N, Khush GS, Sasaki T (1998) A high-density rice genetic linkage map with 2275 markers using, a single F2 population. Genetics 148:479-494
Helentjaris T, Slocum M, Wright S, et al. (1986) Construction of genetic linkage maps in maize and tomato using restriction fragment length polymorphisms. Theor Appl Genet 72:761-769
Huang XQ, Cster, H Ganal MW, Rder MS (2003) Advanced backcross QTL analysis for the identification of quantitative trait loci alleles from wild relatives of wheat (Triticum aestivum L.). Theor Appl Genet 106:1379-1389
Ittu M, Saulescu NN, Hagima I, Ittu G, Mustatea P (2000) Association of Fusarium head blight resistance with gliadin loci in a winter wheat cross. Crop Sci 40:62-67
Kojima S, Takahashi Y, Kobayashi Y, Monna L, Sasaki T, Araki T, Yano M (2002) Hd3a, a rice ortholog of the arabidopsis FT gene, promotes transition to flowering downstream of Hdl under short-day conditions. Plant Cell Physiol 43 (10):1096-1105.
Kolb FL, Bai GH, Muehlbauer GJ, Anderson JA, Smith KP, Fedak G(2001) Host plant resistance genes for Fusarium head blight: mapping and manipulation with molecular markers. Crop Sci 41:611-619
Lander ES, Botstein D (1989) Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 121:185-199
Lee M (1995) DNA markers and plant breeding program. Advance in Agronomy 55:265-344
Luo ZW, Wu CI, Kearsey MJ (2002) Precision and high-resolution mapping of quantitative trait loci by use of recurrent selection, backcross or intercross schemes. Genetics 161 (2):915-929
Ma ZQ, Rder MS, Sorrells ME (1996) Frequencies and sequence characteristics of di-, tri-, tetra-nucleotide microsatellites in wheat. Genome 39:123-130
Ma ZQ, Sorrells ME (1995) Genetic analysis of fertility restoration in wheat using restriction fragment length polymorphisms. Crop Sci 35:1137-1143
Ma ZQ, Sorrells ME (1995) Genetic analysis of fertility restoration in wheat using restriction fragment length polymorphisms. Crop Sci 35:1137-1143
Ma ZQ, Steffenson BJ, Prom LK, Lapitan NLV (2000) Mapping of quantitative trait loci for Fusarium head blight resistance in six-rowed barley. Phytopathology 90:1079-1088
McCouch SR, Kochert G, Yu ZH, Wang ZY, Khush GS, Coffman WR, Tanksley SD (1988) Molecular mapping of rice chromosomes. Theor Appl Genet 76:815-829
Mesterhazy A (1977) Reaction of winter wheat varieties to four Fusarium species. Phytopathologische Zeitschrift 90 (2):104-112
Mesterhazy A (1983) Breeding wheat for resistance to Fusarium graminearum and Fusarium culmorum. Pflanzenzücht 91:295-311
Mesterhazy A (1995) Types and components of resistance to Fusarium head blight. Plant Breed 114:377-386
Michelmore RW, Paran I, Kesseli RV (1991) Identification of markers linked to disease-resistance genes by bulked segregant analysis: A rapid method to detect markers in specific genomic regions by using segregating populations. Proc Natl Acad Sci USA 88:9828-9832
Mielke H (1988) Studies into Fusarium culmorum (W. G. Sm.) Sacc. as the causal agent of foot and head diseases in wheat. Mitteilungen aus der Biologischen Bundesanstalt fuer Land und Forstwirtschaff Berlin Dahlem 238:100-101
Miller JD, Young JC, Sampson DR (1985) Deoxynivalenol and Fusarium head blight resistance in spring cereals. Phytopathol 113:359-367
Nakagawa MO (1955) Studies on ear-scab resistance of wheat plants 2.Genetical factors affecting the inheritance on ear-scab disease of wheat plants. (in Japanese with English summary.) Japan J. Breeding 5:15-22
Otto CD, Kianian SF, Elias EM, Stack RW, Joppa LR (2002) Genetic sissection of a major Fusarium head blight QTL in tetraploid wheat. Plant Mol Biol 48 (5-6):625-632
Paterson AH, DeVema JW, Lanini B, Tanksley SD (1990) Fine mapping of quantitative trait loci using selected overlapping recombinant chromosomes, in a interspecific cross tomato. Genetics 124:735-742
Paterson AH, Lander ES, Hewitt JD, Peterson S, Lincoln SE, Tanksley SD (1988) Resolution of quantitative traits into Mendelian factors using a complete linkage map of restriction fragment length polymorphisms. Nature (London) 335: 721-726
Rder MS, Korzun V, Wendehake K, Plaschke J, Tixier MH, Leroy P, Ganal MW (1998) A microsatellite map of wheat. Genetics 149:2007-2023
Rder MS, Korzun V, Wendehake K, Plaschke J, Tixier MH, Leroy P, Ganal MW (1998). A microsatellite map of wheat. Genetics 149:2007-2023
Saur L (1991) Source of resistance to head blight caused by Fusarium culmorum in bread wheat and related species [Triticeae]. Agronomic 11 (7):535-541.
Sax K (1923) The association of size differences with seed-coat pattern and pigmentation in Phaseolus vulgaris. Genetics 8:552-560
Schroeder HW, Christensen JJ (1963) Factors affecting the resistance of wheat to scab caused by Gibberella zeae. Phytopathology 53:831-838
Shen XR, Ittu M, Ohm H (2003a) Quantitative trait locus conditioning resistance to Fusarium head blight in wheat line F201R. Crop Sci. 43:850-857
Shen XR, Zhou M, Lu W, Ohm H (2003b) Detection of Fusarium head blight resistance QTL in a wheat population using bulked segregant analysis. Theor Appl Genet 106:1041-1047
Singh RP, Ma H, Rajaram S (1995) Genetic analysis of resistance to scab in spring wheat cultivar Frontana. Plant Dis 79 (3):238-240
Snijders CHA (1990) Genetic variation for resistance to Fusarium head blight in bread wheat. Euphytica 50:171-179
Snijders CHA, Krechting CF (1993) Inhibition of deoxynivalenol translocation and fungal colonization in Fusarium head blight resistant wheat. Jacobs T 1993:348
Soller M, Brody T, Genizi A (1976) On the power of experimental designs for the detection of linkage between marker loci and quantitative loci in crosses between inbred lines. Theor Appl Genet 47:35-39
Stack RW, Elias EM, Mitchell-Fetch J, Miller JD, Joppa LR (2002) Fusarium head blight reaction of langdon durum-triticum dicoccoides chromosome substitution lines. Crop Sci 42:637-642
Stack RW, Frohberg RC, Casper H (1997) Reaction of spring wheats incorporating Sumai#3-derived resistance to inoculation with seven Fusarium species. Cereal Res Commun 25:667-671
Stack RW, Miller JD, Joppa LR (2002b) Proposed chromosomal location of FHB resistance genes in additional sets of durum disomic substitution lines derived from different T. dicoccoides accessions. In: National Fusarium Head Blight Forum Proceedings, 7-9 Dec 2002, Cincinnati, pp 217
Stuber CW, Edwards M, Wendel JF (1987) Molecular-marker-facilitated investigations of quantitative trait loci in maize. 2. Factors influencing yield and its component traits. Crop Sci 27:639-648
Takahashi Y, Shomura A, Sasaki T, Yano M (2001) Hd6, a rice quantitative trait locus involved in photoperiod sensitivity, encodes the alpha subunit of protein kinase CK2. Proc Natl Acad Sci USA 98 (14):7922-7927.
Tanksley SD (1993) Mapping polygenes. Annu Rev Genet. 27:205-233
Tanksley SD, Medino-Filho H, Rick CM (1982) Use of naturally occuring enzyme variation to detect and map genes controlling quantitative traits in an interspecific backcross of tomato. Heredity 49:11-25
Tanksley SD, Nelson JC (1996) Advanced backcross QTL analysis: a method for the simultaneous discovery and transfer of valuable QTLs from unadapted germplasm into elite breeding lines. Theor Appl Genet 92:191-203
Van Eeuwijk FA, Mesterhazy A, Kling CI, Ruckenbauer P, Saur L, Buerstmayr H, Lemmens M, Keizer LCP, Maurin N, Snijders CHA (1995) Assessing non-specificity of resistance of wheat to head blight caused by inoculation with European strains of Fusarium culmorum, F. graminearum and F. nivale, using a multiplicative model for interaction. Theor Appl Genet 90:221-228
Waldron BL, Moreno-Sevilla B, Anderson JA, Stack RW, Frohberg RC (1999) RFLP mapping of QTL for Fusarium head blight resistance in wheat. Crop Sci 39:805-811
Weller JI (1986) Maximum likelihood techniques for the mapping and analysis of quantitative trait loci with the aid of genetic marker. Biometrics 42:627-640
Xiao JH, Li J, Grandillo S, Ahn SN, Yuan L, Tanksley SD, McCouch SR (1998) Identification of trait-improving quantitative trait loci alleles from a wild rice relative, Oryza rufipogon. Genetics 150:899-909
Xu DH, Juan HF, Nohda M, Ban T (2001) QTLs mapping of type Ⅰ and type Ⅱ resistance to FHB in wheat. In: National Fusarium Head Blight Forum Proceedings, 10-12 Dec 2001, Cincinnati, pp 40-42
Yamamoto T, Lin SY, Antonio BA, Parco A, Kajiya H, Huang N, Yamamoto K, Nagamura Y, Kurata N, Khush GS, Sasaki T (1998) A high-density rice genetic linkage map with 2275 markers using a single F_2 population. Genetics 148:479-494
Yano M, Katayose Y, Ashikari M, Yamanouchi U, Monna L, Fuse T, Baba T, Yamamoto K, Umehara Y, Nagamura Y, Sasaki T (2000) Hdl, a major photoperiod sensitivity quantitative trait locus in rice, is closely related to the arabidopsis flowering time gene CONSTANS. Plant Cell 12:2473-2484
Zeng ZB (1994) Precision mapping of quantitative trait loci. Genetics 136:1457-1468
Zhou WC, Kolb FL, Bai G, Shaner G, Domier LL (2002) Genetic analysis of scab resistance QTL in wheat with microsatellite and AFLP markers. Genome 45 (4):719-727
Zhou WC, Kolb FL, Bai GH, Shaner G, Domier LL (2000) SSR mapping and sub-arm physical location of a major scab resistance QTL in wheat. In: National Fusarium Head Blight Forum Proceedings, 10-12 Dec 2000, Cincinnati, pp 69-72
Zhu Z, Ren L, Xiang Y, Shen X, Zhang X, Zhou M, Lu W (2000) Identification of RAPD markers linked to scab resistance in the wheat Sumai 3. In: Raupp J, Ma Z, Chen P, Liu D (eds) Proc Int Symp on Wheat Improvement for Scab Resistance. 5-11 May, 2000, Suzhou and Nanjing, China, pp 132-135