应用新型可降解材料修复大鼠腹壁缺损的实验研究
|
摘要
目前,随着腹壁缺损患者的日益增多,腹壁缺损修复材料已成为国内外生物医用材料界研发的热点。现有的腹壁缺损修复材料均为进口产品,价格昂贵,不能适应广大基层医院临床的需要。聚碳酸亚丙酯(PPC)是一种近年来研究较多的脂肪族聚碳酸酯,它无毒、可生物降解、生物相容性好、可塑形性强、成本低,如通过物理、化学方法对其进行改性以提高物理性能,将有望研发出新型腹壁缺损修复材料。本研究在前期在前期研究工作基础上,应用三元稀土催化体系制备出PPC,再分别将不同比例的PPC和聚β-羟基丁酸酯(PHB)共混出改性材料,提高PPC的强度和韧性,研制出一系列新型高分子材料-改性聚碳酸亚丙酯(PM-PPC)。在前期研究中,选用细胞毒性试验、致敏试验、皮肤刺激试验、急性全身毒性试验、溶血试验、热原试验和植入试验对PM-PPC进行生物安全性评价。本研究在以堆肥降解试验验证PM-PPC的可生物降解性能后,充分研究PM-PPC的体外、体内降解性能。原代分离、培养和鉴定Wistar大鼠成纤维细胞,并以其作为种子细胞研究PM-PPC作为腹壁缺损修复材料的体外生物相容性及有效性。建立大鼠腹壁缺损动物模型,以PM-PPC作为腹壁缺损修复材料,进行体内生物有效性研究,并与目前临床应用的聚丙烯材料进行对比。结果表明：新型可降解高分子材料PM-PPC具有较强的物理性能,良好的生物安全性、体内外缓慢降解性和成纤维细胞相容性,能有效地修复大鼠腹壁缺损。本研究结果为自行研发的新型高分子材料——PM-PPC开发为腹壁缺损修复材料提供了可靠的临床前基础实验数据,为PM-PPC进一步的临床研究和应用奠定了坚实的基础。
Due to the trauma, abdominal-wall tumors or population aging etc, the incidence rate of abdominal-wall defect and lateral ventral syndrome are all gradually increased. The application of tension free repair in some operations, i.e, on bdominal-wall defect and lateral ventral syndrome, are accepted gradually and even have become the standard operations in some countries. The patch was used in all kinds of abdominal-wall defect and lateral ventral syndrome including inguinal hernia, lateral ventral syndrome, incisional hernia. Whereas the contraindication is only restrict at children and those whose operating field are infected. The consumption of the patch is up to 1,000,000 each year in all over the world. Currently, most commonly used patch in reparing abdominal-wall defect and lateral ventral syndrome are polypropylene, polyester, expande polytetraflouroethylene (ePTFE), etc. and they are all non-absorbing material.
The application of Polypropylene patch are quite extensive due to their characteristics of stabilization, firm, inertia and fine texture, but the products is so different in their shape, size, density and aperture with relative company. The disadvantage of the Polypropylene patch are as metioned below:crude surfaces; potential adhesions with organs in peritoneal cavity; causing Intestinal fistula by erosing intestinal canal; the formation of skin sinus tract after infection or cicatrix contracture and patch twist. Polyester, which is Dacron, is the secondary biggist consumption patch, only rank after Polypropylene. Polyester patch has the feature of hydrophilicity so that the tissue cicatrix contracture is much lighter than that of heavy weight Polypropylene patch.Whereas it's disadvantage is poor histocompatibility, so the patch must be taken out as long as infection occurs. There are some kinds of expande polytetraflouroethylene are considered as safe due to their moderate adhesions cases,there are seldom the intestinal fistula after being treated with ePTFE. Unfortunately, ePTFE is belongs to the micropore materials which leads to such a situation that seroma might occurs as the pore space is too small to allow fibroblasts, macrophages to crawl in, which must be infected by bacteria. Thus, the patch must be moved finally. Biomaterial patch is novel product in recent study, there are kinds of Biomaterial patch including or non-human source be invented after risking so much infections and operation failures. Whereas, those material is restricted in clinical therapy because of lacking the supporting testimony. The repairing materials metioned above are all imported from overseas so that can not be accepted by patient even our doctors. Therefore, it is extremely important to develop a new, domestic, inexpensive, ideal therapeutic effect, degradable material to deal with abdominal-wall defect and lateral ventral syndrome.
Polypropylene carbonate (PPC), also called poly (propylene carbonate), is a polyalkylene carbonate plastic material, a copolymer of carbon dioxide and propylene oxide, which is a biodegradable plastic. Its nontoxic, no pollution, and good transparence, biocompatibility and plasticity are suitable for being a new type of biomaterial. But its low glass transition temperature, thermostability and hardness make it difficult for PPC to be biomaterial alone. Polyhydroxybutyrate (PHB) is a polyhydroxyalkanoate, a polymer belonging to the polyesters class, which is produced by micro-organisms. It is non toxic, biodegradable, biocompatible so is suitable for medical applications. But its brittleness and bad thermostability make it can't be used in medical applications. Neither PPC nor PHB alon can be used as biomaterial for abdominal-wall defect and lateral ventral syndrome.
In our research, we have developped a series of new biodegradable polymers, porous modified-polypropylene carbonate (PM-PPC), by admixing PPC and PHB at different ratio and salting out to make it multiaperture. PM-PPC combine the good qualities of PPC and PHB, maked it more suitable for medical application. The admixture of PPC and PHB at the ratio of 90:10 can be used as biomaterial for abdominal-wall defect and lateral ventral syndrome. In this research, we have investigated the physico-mechanical function, degradation ability and biological availability of abdominal-wall defect repair of PM-PPC, abstract as follow:
Part I:Research on physical function of PM-PPC and PP. PP is the initial repairing material of abdominal wall used in clinic application. It was developed by Johnson & Johnson Company in 1981 and put on the market afterwards. Now it is accepted by the clinic doctors and patients and widely used in the therapy of clinic abdominal wall injury. What we developed here is the new modified degradable biomaterial PM-PPC. It's a mixed porous material which PHB is 90:10. In this part of the study, PM-PPC and PC were compared on weight, fiber weight, pore size, bending strength, tearing of traction force, maximum traction force, pressure resistance and extension capability under 16N/m2. We demonstrated that there is no significant difference between PM-PPC and PP on these properties. PM-PPC is suitable for the restoration of abdominal wall injury.
PartⅡ:The study of compatibility of fibroblast with porous modified-polypropylene carbonate (PM-PPC). The fibroblast is important for abdominal wall repair and rebuilding. In this study, we isolate and culture the primary Wistar peritoneum fibroblast by tissue culture and identify the cells by immunofluorescence, electron microscopy and vimentin blot. The identified fibroblast as the seed cells, is inoculated into culture plates in 3.5×105 cell concentration and cultured. The material can directly contact with cells, we observe the growth capacity of fibroblasts regularly. On the different time points, we observed the compatibility of materials with fibroblast in vitro by cell counting and scanning electron microscope method of surface materials. The results show that the fibroblast can adhesion, elongation and proliferation on the surface of PM-PPC. PM-PPC have good compatibility with fibroblast which can be repair materials for abdominal wall defection.
PartⅢ:The study of compatibility of porous modified-polypropylene carbonate (PM-PPC) with rats'abdominal wall tissue. We dissociated the preperitoneal space by surgical method, then put the PM-PPC patch and PP patch into the preperitoneal space and closed the abdomen. We observed the fiber production and arrangement, cells number and distribution by HE staining. the expression of tumor growth factor-β(TGF-β) antibody and fiber growth factor (FGF) by immunohistochemistry and the function of fibroblast by electron microscope techniques in 1,3,5,7 and 14 days after surgery. The results show that 3 to 5 days after surgery is the peak expression period of TGF-β. The expression of PM-PPC group and PP group is significantly higher than control, which show PM-PPC can stimulate the overexpression of TGF-βduring the abdominal wall repair, but which have no significant difference with PP group.3 to 5 days after surgery is the peak expression period of FGF. The control group is significant lower than PM-PPC group and PP group, which show PM-PPC can stimulate the overexpression of FGF during the abdominal wall repair, but which have no significant difference with PP group.
The partⅣ:study on the restoration of abdominal wall injury with PM-PPC. Abdominal wall injury animal model was established by surgical resection of rectus abdominis anterior sheath, rectus abdominis. Then, PM-PPC and PP were implanted into the injury position, respectively. Histology and ultrasonography examination were employed to evaluate the restoration process of abdominal wall injury at the week 2,4,8,12 after surgery. At week 12, PM-PPC and PP group exhibited good restoration effect without occurrence of abdominal wall hernia. However, abdominal wall hernia formed in the control group without implanted material at week 12. Rose Bengal-polarized light technique was utilized to detect the collagenⅠ,Ⅲexpression in rectus sheath. PM-PPC and PP could improve the expression of collagenⅠand increase the ratio of collagenⅠandⅢ, which could further enhance the abdominal wall strength and reduce the occurrence of abdominal wall hernia.
Due to the trauma, abdominal-wall tumors or population aging etc, the incidence rate of abdominal-wall defect and lateral ventral syndrome are all gradually increased. The application of tension free repair in some operations, i.e, on bdominal-wall defect and lateral ventral syndrome, are accepted gradually and even have become the standard operations in some countries. The patch was used in all kinds of abdominal-wall defect and lateral ventral syndrome including inguinal hernia, lateral ventral syndrome, incisional hernia. Whereas the contraindication is only restrict at children and those whose operating field are infected. The consumption of the patch is up to 1,000,000 each year in all over the world. Currently, most commonly used patch in reparing abdominal-wall defect and lateral ventral syndrome are polypropylene, polyester, expande polytetraflouroethylene (ePTFE), etc. and they are all non-absorbing material.
The application of Polypropylene patch are quite extensive due to their characteristics of stabilization, firm, inertia and fine texture, but the products is so different in their shape, size, density and aperture with relative company. The disadvantage of the Polypropylene patch are as metioned below:crude surfaces; potential adhesions with organs in peritoneal cavity; causing Intestinal fistula by erosing intestinal canal; the formation of skin sinus tract after infection or cicatrix contracture and patch twist. Polyester, which is Dacron, is the secondary biggist consumption patch, only rank after Polypropylene. Polyester patch has the feature of hydrophilicity so that the tissue cicatrix contracture is much lighter than that of heavy weight Polypropylene patch.Whereas it's disadvantage is poor histocompatibility, so the patch must be taken out as long as infection occurs. There are some kinds of expande polytetraflouroethylene are considered as safe due to their moderate adhesions cases,there are seldom the intestinal fistula after being treated with ePTFE. Unfortunately, ePTFE is belongs to the micropore materials which leads to such a situation that seroma might occurs as the pore space is too small to allow fibroblasts, macrophages to crawl in, which must be infected by bacteria. Thus, the patch must be moved finally. Biomaterial patch is novel product in recent study, there are kinds of Biomaterial patch including or non-human source be invented after risking so much infections and operation failures. Whereas, those material is restricted in clinical therapy because of lacking the supporting testimony. The repairing materials metioned above are all imported from overseas so that can not be accepted by patient even our doctors. Therefore, it is extremely important to develop a new, domestic, inexpensive, ideal therapeutic effect, degradable material to deal with abdominal-wall defect and lateral ventral syndrome.
Polypropylene carbonate (PPC), also called poly (propylene carbonate), is a polyalkylene carbonate plastic material, a copolymer of carbon dioxide and propylene oxide, which is a biodegradable plastic. Its nontoxic, no pollution, and good transparence, biocompatibility and plasticity are suitable for being a new type of biomaterial. But its low glass transition temperature, thermostability and hardness make it difficult for PPC to be biomaterial alone. Polyhydroxybutyrate (PHB) is a polyhydroxyalkanoate, a polymer belonging to the polyesters class, which is produced by micro-organisms. It is non toxic, biodegradable, biocompatible so is suitable for medical applications. But its brittleness and bad thermostability make it can't be used in medical applications. Neither PPC nor PHB alon can be used as biomaterial for abdominal-wall defect and lateral ventral syndrome.
In our research, we have developped a series of new biodegradable polymers, porous modified-polypropylene carbonate (PM-PPC), by admixing PPC and PHB at different ratio and salting out to make it multiaperture. PM-PPC combine the good qualities of PPC and PHB, maked it more suitable for medical application. The admixture of PPC and PHB at the ratio of 90:10 can be used as biomaterial for abdominal-wall defect and lateral ventral syndrome. In this research, we have investigated the physico-mechanical function, degradation ability and biological availability of abdominal-wall defect repair of PM-PPC, abstract as follow:
Part I:Research on physical function of PM-PPC and PP. PP is the initial repairing material of abdominal wall used in clinic application. It was developed by Johnson & Johnson Company in 1981 and put on the market afterwards. Now it is accepted by the clinic doctors and patients and widely used in the therapy of clinic abdominal wall injury. What we developed here is the new modified degradable biomaterial PM-PPC. It's a mixed porous material which PHB is 90:10. In this part of the study, PM-PPC and PC were compared on weight, fiber weight, pore size, bending strength, tearing of traction force, maximum traction force, pressure resistance and extension capability under 16N/m2. We demonstrated that there is no significant difference between PM-PPC and PP on these properties. PM-PPC is suitable for the restoration of abdominal wall injury.
PartⅡ:The study of compatibility of fibroblast with porous modified-polypropylene carbonate (PM-PPC). The fibroblast is important for abdominal wall repair and rebuilding. In this study, we isolate and culture the primary Wistar peritoneum fibroblast by tissue culture and identify the cells by immunofluorescence, electron microscopy and vimentin blot. The identified fibroblast as the seed cells, is inoculated into culture plates in 3.5×105 cell concentration and cultured. The material can directly contact with cells, we observe the growth capacity of fibroblasts regularly. On the different time points, we observed the compatibility of materials with fibroblast in vitro by cell counting and scanning electron microscope method of surface materials. The results show that the fibroblast can adhesion, elongation and proliferation on the surface of PM-PPC. PM-PPC have good compatibility with fibroblast which can be repair materials for abdominal wall defection.
PartⅢ:The study of compatibility of porous modified-polypropylene carbonate (PM-PPC) with rats'abdominal wall tissue. We dissociated the preperitoneal space by surgical method, then put the PM-PPC patch and PP patch into the preperitoneal space and closed the abdomen. We observed the fiber production and arrangement, cells number and distribution by HE staining. the expression of tumor growth factor-β(TGF-β) antibody and fiber growth factor (FGF) by immunohistochemistry and the function of fibroblast by electron microscope techniques in 1,3,5,7 and 14 days after surgery. The results show that 3 to 5 days after surgery is the peak expression period of TGF-β. The expression of PM-PPC group and PP group is significantly higher than control, which show PM-PPC can stimulate the overexpression of TGF-βduring the abdominal wall repair, but which have no significant difference with PP group.3 to 5 days after surgery is the peak expression period of FGF. The control group is significant lower than PM-PPC group and PP group, which show PM-PPC can stimulate the overexpression of FGF during the abdominal wall repair, but which have no significant difference with PP group.
The partⅣ:study on the restoration of abdominal wall injury with PM-PPC. Abdominal wall injury animal model was established by surgical resection of rectus abdominis anterior sheath, rectus abdominis. Then, PM-PPC and PP were implanted into the injury position, respectively. Histology and ultrasonography examination were employed to evaluate the restoration process of abdominal wall injury at the week 2,4,8,12 after surgery. At week 12, PM-PPC and PP group exhibited good restoration effect without occurrence of abdominal wall hernia. However, abdominal wall hernia formed in the control group without implanted material at week 12. Rose Bengal-polarized light technique was utilized to detect the collagenⅠ,Ⅲexpression in rectus sheath. PM-PPC and PP could improve the expression of collagenⅠand increase the ratio of collagenⅠandⅢ, which could further enhance the abdominal wall strength and reduce the occurrence of abdominal wall hernia.
引文
[1]Lo DJ, Bilimoria KY, Pugh CM. Bowel complications after prolene hernia system (PHS) repair:a case report and review of the literature[J]. Hernia,2008,12(4):437-440.
[2]Goswami R, Babor M, Ojo A. Mesh erosion into caecum following laparoscopic repair of inguinal hernia (TAPP):a case report and literature review[J]. J Laparoendosc Adv Surg Tech A,2007,17(5):669-672.
[3]H G. Selecting right mesh[J]. Hernia,1999,3(1):23-26.
[4]Welty G, Klinge U, Klosterhalfen B et al. Functional impairment and complaints following incisional hernia repair with different polypropylene meshes[J]. Hernia,2001, 5(3):142-147.
[5]KLNGEU, B K, V BIK. Impairment of polymer pore size on the interface scar formation in arat mode[J]. J Surg Res,2002, (103):208-214.
[6]Bringman S, Wollert S, Osterberg J et al. Three-year results of a randomized clinical trial of lightweight or standard polypropylene mesh in Lichtenstein repair of primary inguinal hernia[J]. Br J Surg,2006,93(9):1056-1059.
[7]Riaz AA, Ismail M, Barsam A et al. Mesh erosion into the bladder:a late complication of incisional hernia repair. A case report and review of the literature [J]. Hernia,2004,8(2): 158-159.
[8]Ferrante F, Rusconi A, Galimberti A et al. Hernia repair in the Lombardy region in 2000: preliminary results[J]. Hernia,2004,8(3):247-251.
[9]Gonzalez R, Fugate K, McClusky D,3rd et al. Relationship between tissue ingrowth and mesh contraction[J]. World J Surg,2005,29(8):1038-1043.
[10]Petersen S, Henke G, Freitag M et al. Deep prosthesis infection in incisional hernia repair: predictive factors and clinical outcome[J]. Eur J Surg,2001,167(6):453-457.
[11]Bellon JM, Contreras LA, Sabater C et al. Pathologic and clinical aspects of repair of large incisional hernias after implant of a polytetrafluoroethylene prosthesis [J]. World J Surg,1997,21(4):402-406; discussion 406-407.
[12]Matthews BD, Mostafa G, Carbonell AM et al. Evaluation of adhesion formation and host tissue response to intra-abdominal polytetrafluoroethylene mesh and composite prosthetic mesh[J]. J Surg Res,2005,123(2):227-234.
[13]LeBlanc KA. A new method to insert the DualMesh prosthesis for laparoscopic ventral herniorrhaphy[J]. JSLS,2002,6(4):349-352.
[14]Junge K, Klinge U, Rosch R et al. Improved collagen type Ⅰ/Ⅲ ratio at the interface of gentamicin-supplemented polyvinylidenfluoride mesh materials[J]. Langenbecks Arch Surg,2007,392(4):465-471.
[15]Klinge U, Klosterhalfen B, Ottinger AP et al. PVDF as a new polymer for the construction of surgical meshes[J]. Biomaterials,2002,23(16):3487-3493.
[16]Holste JL. Are meshes with lightweight construction strong enough?[J]. Int Surg,2005, 90(3 Suppl):S10-12.
[17]Novitsky YW, Harrell AG, Hope WW et al. Meshes in hernia repair [J]. Surg Technol Int, 2007,16:123-127.
[18]Jacob BP, Hogle NJ, Durak E et al. Tissue ingrowth and bowel adhesion formation in an animal comparative study:polypropylene versus Proceed versus Parietex Composite[J]. Surg Endosc,2007,21(4):629-633.
[19]Junge K, Klinge U, Rosch R et al. Functional and morphologic properties of a modified mesh for inguinal hernia repair[J]. World J Surg,2002,26(12):1472-1480.
[20]Holzheimer RG. First results of Lichtenstein hernia repair with Ultrapro-mesh as cost saving procedure--quality control combined with a modified quality of life questionnaire (SF-36) in a series of ambulatory operated patients[J]. Eur J Med Res,2004,9(6): 323-327.
[21]Carbonell AM, Matthews BD, Dreau D et al. The susceptibility of prosthetic biomaterials to infection[J]. Surg Endosc,2005,19(3):430-435.
[22]Schug-Pass C, Tamme C, Tannapfel A et al. A lightweight polypropylene mesh (TiMesh) for laparoscopic intraperitoneal repair of abdominal wall hernias:comparison of biocompatibility with the DualMesh in an experimental study using the porcine model[J]. Surg Endosc,2006,20(3):402-409.
[23]Burger JW, Halm JA, Wijsmuller AR et al. Evaluation of new prosthetic meshes for ventral hernia repair[J]. Surg Endosc,2006,20(8):1320-1325.
[24]Harrell AG, Novitsky YW, Peindl RD et al. Prospective evaluation of adhesion formation and shrinkage of intra-abdominal prosthetics in a rabbit model[J]. Am Surg,2006,72(9): 808-813; discussion 813-804.
[25]Bellows CF, Albo D, Berger DH et al. Abdominal wall repair using human acellular dermis[J]. Am J Surg,2007,194(2):192-198.
[26]Misra S, Raj PK, Tarr SM et al. Results of AlloDerm use in abdominal hernia repair[J]. Hernia,2008,12(3):247-250.
[27]Klosterhalfen B, Junge K, Klinge U. The lightweight and large porous mesh concept for hernia repair[J]. Expert Rev Med Devices,2005,2(1):103-117.
[28]Caldwell DM, Preston FG. An unusual case of traumatic diaphragmatic hernia with successful operation[J]. Dis Chest,1949,16(4):488-494.
[29]Usher FC, Hill JR, Ochsner JL. Hernia repair with Marlex mesh. A comparison of techniques[J]. Surgery,1959,46:718-724.
[30]Stoppa R, Abourachid H, Duclaye C et al. [Plastic surgery of inguinal hernia. Interposition without fixation of dacron mesh by subperitoneal median approach] [J]. Nouv Presse Med,1973,2(29):1949-1951.
[31]Badrinas F, Rodriguez-Roisin R, Rives A et al. Multiple myeloma with pleural involvement[J].AmRev RespirDis,1974,110(1):82-87.
[32]Lichtenstein IL. Repair of large diffuse lumbar hernias by an extraperitoneal binder technique[J]. Am J Surg,1986,151(4):501-504.
[33]Rutkow IM. A selective history of groin herniorrhaphy in the 20th century[J]. Surg Clin North Am,1993,73(3):395-4-11.
[34]Baranowski D, Edel G, Grunert J. [Osteonecrosis following TEP (total endoprosthesis) exchange, intraoperative femur fracture and multiple cerclages][J]. Chirurg,1989,60(11): 815-818.
[35]Wang XP, Pan JH, Li WH et al. Study on the supramolecular system of TAPP with cyclodextrins by polarography[J]. Talanta,2001,54(5):805-810.
[36]Rieger N, Brundell S. Colovesical fistula secondary to laparoscopic transabdominal preperitoneal polypropylene (TAPP) mesh hernioplasty[J]. Surg Endosc,2002,16(1): 218-219.
[37]Michel P, Wullstein C, Hopt UT. [Pyoderma gangrenosum after TAPP hernioplasty. A rare differential necrotizing wound infection diagnosis][J]. Chirurg,2001,72(12):1501-1503.
[38]Kapiris SA, Brough WA, Royston CM et al. Laparoscopic transabdominal preperitoneal (TAPP) hernia repair. A 7-year two-center experience in 3017patients[J]. Surg Endosc, 2001,15(9):972-975.
[39]Smith AI, Royston CM, Sedman PC. Stapled and nonstapled laparoscopic transabdominal preperitoneal (TAPP) inguinal hernia repair. A prospective randomized trial [J]. Surg Endosc,1999,13(8):804-806.
[40]Catani M, De Milito R, Spaziani E et al. [Laparoscopic inguinal hernia repair "IPOM" vs "open tension free". Preliminary results of a prospective randomized study][J]. Minerva Chir,2003,58(6):783-789.
[41]Catani M,De Milito R, Materia A et al. [Laparoscopic inguinal hernia repair "IPOM" with Dual-Mesh][J]. Ann Ital Chir,2003,74(1):53-60; discussion 60-52.
[42]Schmidt J, Carbajo MA, Lampert R et al. Laparoscopic intraperitoneal onlay polytetrafluoroethylene mesh repair (IPOM) for inguinal hernia during spinal anesthesia in patients with severe medical conditions [J]. Surg Laparosc Endosc Percutan Tech,2001, 11(1):34-37.
[43]Lal P, Philips P, Saxena KN et al. Laparoscopic total extraperitoneal (TEP) inguinal hernia repair under epidural anesthesia:a detailed evaluation[J]. Surg Endosc,2007,21(4): 595-601.
[44]Schwab R, Willms A, Kroger A et al. Less chronic pain following mesh fixation using a fibrin sealant in TEP inguinal hernia repair[J]. Hernia,2006,10(3):272-277.
[45]Chowbey PK, Bagchi N, Goel A et al. Mesh migration into the bladder after TEP repair:a rare case report[J]. Surg Laparosc Endosc Percutan Tech,2006,16(1):52-53.
[46]Dulucq JL, Wintringer P, Mahajna A. Totally extraperitoneal (TEP) hernia repair after radical prostatectomy or previous lower abdominal surgery:is it safe? A prospective study[J]. Surg Endosc,2006,20(3):473-476.
[47]Sutalo N, Maricic A, Kozomara D et al. Comparison of results of surgical treatments of primary inguinal hernia with flat polypropylene mesh and three-dimensional prolene (Phs) mesh--one year follow up[J]. Coll Antropol,2010,34 Suppl 1:129-133.
[48]Kibil W, Matyja A, Mocny G et al. [Treatment of the inguinal haernias with the use of synthetic mesh with prolen hernia system (PHS) and Robbins-Rutkow methods--review of outcomes][J]. Folia Med Cracov,2008,49(1-2):49-55.
[49]Farrakha M, Shyam V, Bebars GA et al. Ambulatory inguinal hernia repair with prolene hernia system (PHS)[J]. Hernia,2006,10(1):2-6.
[50]Zandi G, Vasquez G, Buonanno A et al. [PHS Repair in femoral hernia surgery][J]. Minerva Chir,2003,58(6):797-799.
[51]Feleshtyns'kyi la P, Ihnatovs'kyi Iu V, Piotrovych SM et al. [Surgical treatment of inguinal hernia by a polypropylene net and PHS system][J]. Klin Khir,2003, (6):19-20.
[52]Varga L, Leindler L, Hodi Z et al. [A new method of tension-free inguinal hernia repair: "PROLENE hernia system" (PHS) (pilot study)][J]. Magy Seb,2000,53(2):67-68.
[53]Melling AC, Leaper DJ. The impact of warming on pain and wound healing after hernia surgery:a preliminary study[J]. J Wound Care,2006,15(3):104-108.
[54]Junge K, Klinge U, Klosterhalfen B et al. Review of wound healing with reference to an unrepairable abdominal hernia[J]. Eur J Surg,2002,168(2):67-73.
[55]Lemke H, Imhoff M, Lohlein D. [Increased wound healing disorders in patients with inguinal hernia caused by administration of antithrombotic agents in the abdominal wall][J]. Chirurg,1994,65(8):714-716.
[56]严玉兰,刘洋,步雪峰.ECM支架构建肺成纤维细胞三维培养模型研究[J].中国生物医学工程学报,2008,27(6)：900-905.
[57]饶寒敏,徐荣辉,朱雅萍.家兔皮肤成纤维细胞在体外培养中的成骨作用(纤维录像与四环素标记观察)[J].中华骨科杂志,1995,15(5)：295-297.
[58]Jung SY, Lim SM, Albertorio F et al. The Vroman effect:a molecular level description of fibrinogen displacement[J]. J Am Chem Soc,2003,125(42):12782-12786.
[59]Turbill P, Beugeling T, Poot AA. Proteins involved in the Vroman effect during exposure of human blood plasma to glass and polyethylene[J]. Biomaterials,1996,17(13): 1279-1287.
[60]Scott CF. Mechanism of the participation of the contact system in the Vroman effect. Review and summary[J]. J Biomater Sci Polym Ed,1991,2(3):173-181.
[61]Hartmann H, Lubbers B, Casaretto M et al. Rapid quantification of C3a and C5a using a combination of chromatographic and immunoassay procedures[J]. J Immunol Methods, 1993,166(1):35-44.
[62]Pease JE, Barker MD. N-linked glycosylation of the C5a receptor[J]. Biochem Mol Biol Int,1993,31(4):719-726.
[63]Mery L, Boulay F. Evidence that the extracellular N-terminal domain of C5aR contains amino-acid residues crucial for C5abinding[J]. Eur J Haematol,1993,51(5):282-287.
[64]Gerard NP, Bao L, Xiao-Ping H et al. Human chemotaxis receptor genes cluster at 19q13.3-13.4. Characterization of the human C5a receptor gene[J].Biochemistry,1993, 32(5):1243-1250.
[65]Van Epps DE, Simpson SJ, Johnson R. Relationship of C5a receptor modulation to the functional responsiveness of human polymorphonuclear leukocytes to C5a[J]. J Immunol, 1993,150(1):246-252.
[66]Dobos GJ, Andre M, Bohler J et al. Inhibition of C5a-induced actin polymerization, chemotaxis, and phagocytosis of human polymorphonuclear neutrophils incubated in a glucose-based dialysis solution[J]. Adv Perit Dial,1993,9:307-311.
[67]Sluijter JP, Smeets MB, Velema E et al. Increase in collagen turnover but not in collagen fiber content is associated with flow-induced arterial remodeling[J]. J Vasc Res,2004, 41(6):546-555.
[68]Iba Y, Shibata A, Kato M et al. Possible involvement of mast cells in collagen remodeling in the late phase of cutaneous wound healing in mice[J]. Int Immunopharmacol,2004, 4(14):1873-1880.
[69]Kondo S, Kagami S, Urushihara M et al. Transforming growth factor-betal stimulates collagen matrix remodeling through increased adhesive and contractive potential by human renal fibroblasts[J]. Biochim Biophys Acta,2004,1693(2):91-100.
[70]Ferri N, Carragher NO, Raines EW. Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling:potential implications in atherosclerosis and lymphangioleiomyomatosis[J]. Am J Pathol,2004,164(5):1575-1585.
[71]Hurwitz C, Rosano CL, Peabody RA. Excretion of ultraviolet-absorbing material by leaky and non-leaky strains of Escherichia coli exposed to streptomycin[J]. Biochim Biophys Acta,1963,72:80-86.
[72]Szabo S, Istvan G. [Skin closure in inguinal hernia repair with rapidly absorbing Polyglactin 910/370 (Vicryl-Rapide) suture material][J]. Magy Seb,2002,55(2):77-80.
[73]Bornemisza G, Ladanyi J, Miko I. [Experimental skin replacement by means of absorbing alloplastic material][J]. Z Exp Chir,1976,9(3):150-154.
[74]Rausa L, Arena E, Gebbia N et al. On the possible causes of the release of material absorbing at 260 m-mu by streptomycin treated E. coli cells (K 12 and B)[J]. J Antibiot (Tokyo),1967,20(3):142-148.
[75]Taneli F, Aydede H, Vatansever S et al. The long-term effect of mesh bioprosthesis in inguinal hernia repair on testicular nitric oxide metabolism and apoptosis in rat testis[J]. Cell Biochem Funct,2005,23(3):213-220.
[76]Knight BC, Tait WF. Dacron patch infection following carotid endarterectomy:a systematic review of the literature [J]. Eur J Vasc Endovasc Surg,2009,37(2):140-148.
[77]Byer A, Keys RC, Panush D et al. Late infection of a Dacron carotid endarterectomy patch--a case report[J]. Vasc Surg,2001,35(6):469-472.
[78]Sternbergh WC,3rd. Regarding "Dacron carotid patch infection:a report of eight cases"[J]. J Vasc Surg,2001,33(3):663-664.
[79]Rizzo A, Hertzer NR, O'Hara P J et al. Dacron carotid patch infection:a report of eight cases[J]. J Vasc Surg,2000,32(3):602-606.
[80]Azad R, Mehta MR. Is the test patch useful in determining safety against operative infection?[J]. Indian J Ophthalmol,1989,37(1):20-23.
[81]Fourestier M. [Detection and prevention of tuberculous primary infection by use of tuberculin patch-tests and BCG-S (systematic) vaccinations in children of a large French city; Montreuil experiment,1948-1952.][J]. Acta Tuberc Belg,1954,45(3):305-319.
[82]Mukhopadhyay S, Gowtham S, Scheicher RH et al. Theoretical study of physisorption of nucleobases on boron nitride nanotubes:a new class of hybrid nano-biomaterials[J]. Nanotechnology,2010,21(16):165703.
[83]Tangpasuthadol V, Pendharkar SM, Peterson RC et al. Hydrolytic degradation of tyrosine-derived polycarbonates, a class of new biomaterials. Part II:3-yr study of polymeric devices[J]. Biomaterials,2000,21(23):2379-2387.
[84]Barbucci R, Magnani A, Baszkin A et al. Physico-chemical surface characterization of hyaluronic acid derivatives as a new class of biomaterials [J]. J Biomater Sci Polym Ed, 1993,4(3):245-273.
[85]Chirila TV, Thompson DE, Constable IJ. In vitro cytotoxicity of melanized poly (2-hydroxyethyl methacrylate) hydrogels, a novel class of ocular biomaterials[J]. J Biomater Sci Polym Ed,1992,3(6):481-498.
[86]de Souza VK, Harrowell P. Rigidity percolation and the spatial heterogeneity of soft modes in disordered materials [J]. Proc Natl Acad Sci USA,2009,106(36):15136-15141.
[87]Llorens J, Pera-Titus M. A thermodynamic analysis of gas adsorption on microporous materials:evaluation of energy heterogeneity[J]. J Colloid Interface Sci,2009,331(2): 302-311.
[88]Wassenaar LI, Hobson KA. Stable-hydrogen isotope heterogeneity in keratinous materials: mass spectrometry and migratory wildlife tissue subsampling strategies [J]. Rapid Commun Mass Spectrom,2006,20(16):2505-2510.
[89]Gritti F, Guiochon G. A chromatographic estimate of the degree of surface heterogeneity of RPLC packing materials.Ⅲ. Endcapped amido-embedded reversed phase[J]. J Chromatogr A,2006,1103(1):69-82.
[90]Marinenko R, Leigh S. Heterogeneity evaluation of research materials for microanalysis standards certification[J]. Microsc Microanal,2004,10(4):491-506.
[91]Pak Yu N, Vdovkin AV, Borodachyov AD. The effect of heterogeneity in gamma-ray albedo analysis of mineral raw materials[J]. Appl Radiat Isot,2001,54(3):509-517.
[92]Charnay C, Lagerge S, Partyka S. Assessment of the Surface Heterogeneity of Talc Materials[J]. J Colloid Interface Sci,2001,233(2):250-258.
[93]Taner T, Cima RR, Larson DW et al. The use of human acellular dermal matrix for parastomal hernia repair in patients with inflammatory bowel disease:a novel technique to repair fascial defects[J]. Dis Colon Rectum,2009,52(2):349-354.
[94]Roth JS, Dexter DD, Lumpkins K et al. Hydrated vs. freeze-dried human acellular dermal matrix for hernia repair:a comparison in a rabbit model[J]. Hernia,2009,13(2):201-207.
[95]Candage R, Jones K, Luchette FA et al. Use of human acellular dermal matrix for hernia repair:friend or foe?[J]. Surgery,2008,144(4):703-709; discussion 709-711.
[96]Milburn ML, Holton LH, Chung TL et al. Acellular dermal matrix compared with synthetic implant material for repair of ventral hernia in the setting of peri-operative Staphylococcus aureus implant contamination:a rabbit model[J]. Surg Infect (Larchmt), 2008,9(4):433-442.
[97]Blatnik J, Jin J, Rosen M. Abdominal hernia repair with bridging acellular dermal matrix--an expensive hernia sac[J]. Am J Surg,2008,196(1):47-50.
[98]Jin J, Rosen MJ, Blatnik J et al. Use of acellular dermal matrix for complicated ventral hernia repair:does technique affect outcomes?[J]. J Am Coll Surg,2007,205(5):654-660.
[99]Bruen K, Downey E. Successful repair of a diaphragmatic hernia through a pericardial window with acellular dermal matrix[J]. J Laparoendosc Adv Surg Tech A,2007,17(3): 383-386.
[100]Ringley CD, Bochkarev V, Ahmed SI et al. Laparoscopic hiatal hernia repair with human acellular dermal matrix patch:our initial experience [J]. Am J Surg,2006,192(6):767-772.
[101]Silverman RP, Li EN, Holton LH,3rd et al. Ventral hernia repair using allogenic acellular dermal matrix in a swine model[J]. Hernia,2004,8(4):336-342.
[102]Pennisi VR, Klabunde EH, Mc GM et al. The use of Marlex 50 in plastic and reconstructive surgery. Ⅱ. Clinical observations [J]. Plast Reconstr Surg Transplant Bull, 1962,30:254-262.
[103]Pennisi VR, Faggella RM, Jr., Ott BS et al. The use of Marlex 50 in plastic and reconstructive surgery. Ⅰ. Experimental observations [J]. Plast Reconstr Surg Transplant Bull,1962,30:247-253.
[104]Harrington OB, Beall AC, Jr., Morris GC, Jr. et al. Circumferential replacement of the trachea with Marlex mesh[J]. Am Surg,1962,28:217-223.
[105]Greenberg SD, Beall AC, Jr., Wallace SA. Tracheal prosthesis:an experimental study with Marlex[J].Exp MolPathol,1962,1:141-150.
[106]Beall AC, Jr., Harrington OB, Greenberg SD et al. Tracheal replacement with heavy Marlex mesh. Circumferential replacement of the cervical trachea[J]. Arch Surg,1962,84: 390-396.
[107]Usher FC. Hernia repair with Marlex mesh. An analysis of 541 cases[J]. Arch Surg,1962, 84:325-328.
[108]Ferrara R, Imperiale S, Polato R et al. Abdominal incisional hernia repair. Intraperitoneal prosthetic technique using Bard Kugel Composix Mesh[J]. Chir Ital,2007,59(5): 735-742.
[109]Licheri S, Erdas E, Pomata M et al. Femoral hernia repair with Bard Mesh Dart Plug[J]. Chir Ital,2004,56(5):705-710.
[110]Kelly SE, Ehlers J, Llovera I et al. Comparison of tissue reaction to nylon and prolene sutures in rabbit iris and cornea[J]. Ophthalmic Surg,1975,6(4):105-110.
[111]Gao M, Han J, Tian J et al. Vypro II mesh for inguinal hernia repair:a meta analysis of randomized controlled trials[J]. Ann Surg,2010,251(5):838-842.
[112]Lim YN, Muller R, Corstiaans A et al. A long-term review of posterior colporrhaphy with Vypro 2 mesh[J]. Int Urogynecol J Pelvic Floor Dysfunct,2007,18(9):1053-1057.
[113]Puccio F, Solazzo M, Marciano P. Comparison of three different mesh materials in tension-free inguinal hernia repair:prolene versus Vypro versus surgisis[J]. Int Surg,2005, 90(3 Suppl):S21-23.
[114]Rosch R, Junge K, Quester R et al. Vypro II mesh in hernia repair:impact of polyglactin on long-term incorporation in rats[J]. Eur Surg Res,2003,35(5):445-450.
[115]Guidoin R, Levaillant PA, Marois M et al. [Polyethylene terephtalate (Dacron) prostheses as arterial substitutes. Value of commercial grafts as abdominal aorta substitutes in the dog (author's transl)][J]. J Mal Vasc,1980,5(1):3-12.
[116]Hazebroek EJ, Leibman S, Smith GS. Erosion of a composite PTFE/ePTFE mesh after hiatal hernia repair[J]. Surg Laparosc Endosc Percutan Tech,2009,19(2):175-177.
[117]Iannitti DA, Hope WW, Tsikitis V. Strength of tissue attachment to composite and ePTFE grafts after ventral hernia repair[J]. JSLS,2007,11(4):415-421.
[118]Huschitt N, Feller M, Lotspeich E et al. [Open intraperitoneal hernia repair for treatment of abdominal wall defects--early results by placement of a polypropylene-ePTFE-mesh][J]. Zentralbl Chir,2006,131(1):57-61.
[119]Koehler RH, Begos D, Berger D et al. Minimal adhesions to ePTFE mesh after laparoscopic ventral incisional hernia repair:reoperative findings in 65 cases[J]. Zentralbl Chir,2003,128(8):625-630.
[120]Gillion JF, Galy M, Jan C et al. [Repair of inguinal hernia by properitoneal positioning of an ePTFE soft patch (112 patches--75 patients)][J]. Ann Chir,1993,47(7):609-615.
[121]Amid PK, Shulman AG, Lichtenstein IL et al. Biomaterials for abdominal wall hernia surgery and principles of their applications [J]. Langenbecks Arch Chir,1994,379(3): 168-171.
[122]Maurice, Arregui, Abrahamson J et al. Abdominal Wall Hernias[M]. Berlin:Springer, 2001:170-282.
[123]J.Robert, Fitzgibbons, A G et al. Nyhus & CONDON'S Herrnia[J].5th edition,2001, Lippincolltt Williams Wilkins:170-282.
[2]Goswami R, Babor M, Ojo A. Mesh erosion into caecum following laparoscopic repair of inguinal hernia (TAPP):a case report and literature review[J]. J Laparoendosc Adv Surg Tech A,2007,17(5):669-672.
[3]H G. Selecting right mesh[J]. Hernia,1999,3(1):23-26.
[4]Welty G, Klinge U, Klosterhalfen B et al. Functional impairment and complaints following incisional hernia repair with different polypropylene meshes[J]. Hernia,2001, 5(3):142-147.
[5]KLNGEU, B K, V BIK. Impairment of polymer pore size on the interface scar formation in arat mode[J]. J Surg Res,2002, (103):208-214.
[6]Bringman S, Wollert S, Osterberg J et al. Three-year results of a randomized clinical trial of lightweight or standard polypropylene mesh in Lichtenstein repair of primary inguinal hernia[J]. Br J Surg,2006,93(9):1056-1059.
[7]Riaz AA, Ismail M, Barsam A et al. Mesh erosion into the bladder:a late complication of incisional hernia repair. A case report and review of the literature [J]. Hernia,2004,8(2): 158-159.
[8]Ferrante F, Rusconi A, Galimberti A et al. Hernia repair in the Lombardy region in 2000: preliminary results[J]. Hernia,2004,8(3):247-251.
[9]Gonzalez R, Fugate K, McClusky D,3rd et al. Relationship between tissue ingrowth and mesh contraction[J]. World J Surg,2005,29(8):1038-1043.
[10]Petersen S, Henke G, Freitag M et al. Deep prosthesis infection in incisional hernia repair: predictive factors and clinical outcome[J]. Eur J Surg,2001,167(6):453-457.
[11]Bellon JM, Contreras LA, Sabater C et al. Pathologic and clinical aspects of repair of large incisional hernias after implant of a polytetrafluoroethylene prosthesis [J]. World J Surg,1997,21(4):402-406; discussion 406-407.
[12]Matthews BD, Mostafa G, Carbonell AM et al. Evaluation of adhesion formation and host tissue response to intra-abdominal polytetrafluoroethylene mesh and composite prosthetic mesh[J]. J Surg Res,2005,123(2):227-234.
[13]LeBlanc KA. A new method to insert the DualMesh prosthesis for laparoscopic ventral herniorrhaphy[J]. JSLS,2002,6(4):349-352.
[14]Junge K, Klinge U, Rosch R et al. Improved collagen type Ⅰ/Ⅲ ratio at the interface of gentamicin-supplemented polyvinylidenfluoride mesh materials[J]. Langenbecks Arch Surg,2007,392(4):465-471.
[15]Klinge U, Klosterhalfen B, Ottinger AP et al. PVDF as a new polymer for the construction of surgical meshes[J]. Biomaterials,2002,23(16):3487-3493.
[16]Holste JL. Are meshes with lightweight construction strong enough?[J]. Int Surg,2005, 90(3 Suppl):S10-12.
[17]Novitsky YW, Harrell AG, Hope WW et al. Meshes in hernia repair [J]. Surg Technol Int, 2007,16:123-127.
[18]Jacob BP, Hogle NJ, Durak E et al. Tissue ingrowth and bowel adhesion formation in an animal comparative study:polypropylene versus Proceed versus Parietex Composite[J]. Surg Endosc,2007,21(4):629-633.
[19]Junge K, Klinge U, Rosch R et al. Functional and morphologic properties of a modified mesh for inguinal hernia repair[J]. World J Surg,2002,26(12):1472-1480.
[20]Holzheimer RG. First results of Lichtenstein hernia repair with Ultrapro-mesh as cost saving procedure--quality control combined with a modified quality of life questionnaire (SF-36) in a series of ambulatory operated patients[J]. Eur J Med Res,2004,9(6): 323-327.
[21]Carbonell AM, Matthews BD, Dreau D et al. The susceptibility of prosthetic biomaterials to infection[J]. Surg Endosc,2005,19(3):430-435.
[22]Schug-Pass C, Tamme C, Tannapfel A et al. A lightweight polypropylene mesh (TiMesh) for laparoscopic intraperitoneal repair of abdominal wall hernias:comparison of biocompatibility with the DualMesh in an experimental study using the porcine model[J]. Surg Endosc,2006,20(3):402-409.
[23]Burger JW, Halm JA, Wijsmuller AR et al. Evaluation of new prosthetic meshes for ventral hernia repair[J]. Surg Endosc,2006,20(8):1320-1325.
[24]Harrell AG, Novitsky YW, Peindl RD et al. Prospective evaluation of adhesion formation and shrinkage of intra-abdominal prosthetics in a rabbit model[J]. Am Surg,2006,72(9): 808-813; discussion 813-804.
[25]Bellows CF, Albo D, Berger DH et al. Abdominal wall repair using human acellular dermis[J]. Am J Surg,2007,194(2):192-198.
[26]Misra S, Raj PK, Tarr SM et al. Results of AlloDerm use in abdominal hernia repair[J]. Hernia,2008,12(3):247-250.
[27]Klosterhalfen B, Junge K, Klinge U. The lightweight and large porous mesh concept for hernia repair[J]. Expert Rev Med Devices,2005,2(1):103-117.
[28]Caldwell DM, Preston FG. An unusual case of traumatic diaphragmatic hernia with successful operation[J]. Dis Chest,1949,16(4):488-494.
[29]Usher FC, Hill JR, Ochsner JL. Hernia repair with Marlex mesh. A comparison of techniques[J]. Surgery,1959,46:718-724.
[30]Stoppa R, Abourachid H, Duclaye C et al. [Plastic surgery of inguinal hernia. Interposition without fixation of dacron mesh by subperitoneal median approach] [J]. Nouv Presse Med,1973,2(29):1949-1951.
[31]Badrinas F, Rodriguez-Roisin R, Rives A et al. Multiple myeloma with pleural involvement[J].AmRev RespirDis,1974,110(1):82-87.
[32]Lichtenstein IL. Repair of large diffuse lumbar hernias by an extraperitoneal binder technique[J]. Am J Surg,1986,151(4):501-504.
[33]Rutkow IM. A selective history of groin herniorrhaphy in the 20th century[J]. Surg Clin North Am,1993,73(3):395-4-11.
[34]Baranowski D, Edel G, Grunert J. [Osteonecrosis following TEP (total endoprosthesis) exchange, intraoperative femur fracture and multiple cerclages][J]. Chirurg,1989,60(11): 815-818.
[35]Wang XP, Pan JH, Li WH et al. Study on the supramolecular system of TAPP with cyclodextrins by polarography[J]. Talanta,2001,54(5):805-810.
[36]Rieger N, Brundell S. Colovesical fistula secondary to laparoscopic transabdominal preperitoneal polypropylene (TAPP) mesh hernioplasty[J]. Surg Endosc,2002,16(1): 218-219.
[37]Michel P, Wullstein C, Hopt UT. [Pyoderma gangrenosum after TAPP hernioplasty. A rare differential necrotizing wound infection diagnosis][J]. Chirurg,2001,72(12):1501-1503.
[38]Kapiris SA, Brough WA, Royston CM et al. Laparoscopic transabdominal preperitoneal (TAPP) hernia repair. A 7-year two-center experience in 3017patients[J]. Surg Endosc, 2001,15(9):972-975.
[39]Smith AI, Royston CM, Sedman PC. Stapled and nonstapled laparoscopic transabdominal preperitoneal (TAPP) inguinal hernia repair. A prospective randomized trial [J]. Surg Endosc,1999,13(8):804-806.
[40]Catani M, De Milito R, Spaziani E et al. [Laparoscopic inguinal hernia repair "IPOM" vs "open tension free". Preliminary results of a prospective randomized study][J]. Minerva Chir,2003,58(6):783-789.
[41]Catani M,De Milito R, Materia A et al. [Laparoscopic inguinal hernia repair "IPOM" with Dual-Mesh][J]. Ann Ital Chir,2003,74(1):53-60; discussion 60-52.
[42]Schmidt J, Carbajo MA, Lampert R et al. Laparoscopic intraperitoneal onlay polytetrafluoroethylene mesh repair (IPOM) for inguinal hernia during spinal anesthesia in patients with severe medical conditions [J]. Surg Laparosc Endosc Percutan Tech,2001, 11(1):34-37.
[43]Lal P, Philips P, Saxena KN et al. Laparoscopic total extraperitoneal (TEP) inguinal hernia repair under epidural anesthesia:a detailed evaluation[J]. Surg Endosc,2007,21(4): 595-601.
[44]Schwab R, Willms A, Kroger A et al. Less chronic pain following mesh fixation using a fibrin sealant in TEP inguinal hernia repair[J]. Hernia,2006,10(3):272-277.
[45]Chowbey PK, Bagchi N, Goel A et al. Mesh migration into the bladder after TEP repair:a rare case report[J]. Surg Laparosc Endosc Percutan Tech,2006,16(1):52-53.
[46]Dulucq JL, Wintringer P, Mahajna A. Totally extraperitoneal (TEP) hernia repair after radical prostatectomy or previous lower abdominal surgery:is it safe? A prospective study[J]. Surg Endosc,2006,20(3):473-476.
[47]Sutalo N, Maricic A, Kozomara D et al. Comparison of results of surgical treatments of primary inguinal hernia with flat polypropylene mesh and three-dimensional prolene (Phs) mesh--one year follow up[J]. Coll Antropol,2010,34 Suppl 1:129-133.
[48]Kibil W, Matyja A, Mocny G et al. [Treatment of the inguinal haernias with the use of synthetic mesh with prolen hernia system (PHS) and Robbins-Rutkow methods--review of outcomes][J]. Folia Med Cracov,2008,49(1-2):49-55.
[49]Farrakha M, Shyam V, Bebars GA et al. Ambulatory inguinal hernia repair with prolene hernia system (PHS)[J]. Hernia,2006,10(1):2-6.
[50]Zandi G, Vasquez G, Buonanno A et al. [PHS Repair in femoral hernia surgery][J]. Minerva Chir,2003,58(6):797-799.
[51]Feleshtyns'kyi la P, Ihnatovs'kyi Iu V, Piotrovych SM et al. [Surgical treatment of inguinal hernia by a polypropylene net and PHS system][J]. Klin Khir,2003, (6):19-20.
[52]Varga L, Leindler L, Hodi Z et al. [A new method of tension-free inguinal hernia repair: "PROLENE hernia system" (PHS) (pilot study)][J]. Magy Seb,2000,53(2):67-68.
[53]Melling AC, Leaper DJ. The impact of warming on pain and wound healing after hernia surgery:a preliminary study[J]. J Wound Care,2006,15(3):104-108.
[54]Junge K, Klinge U, Klosterhalfen B et al. Review of wound healing with reference to an unrepairable abdominal hernia[J]. Eur J Surg,2002,168(2):67-73.
[55]Lemke H, Imhoff M, Lohlein D. [Increased wound healing disorders in patients with inguinal hernia caused by administration of antithrombotic agents in the abdominal wall][J]. Chirurg,1994,65(8):714-716.
[56]严玉兰,刘洋,步雪峰.ECM支架构建肺成纤维细胞三维培养模型研究[J].中国生物医学工程学报,2008,27(6)：900-905.
[57]饶寒敏,徐荣辉,朱雅萍.家兔皮肤成纤维细胞在体外培养中的成骨作用(纤维录像与四环素标记观察)[J].中华骨科杂志,1995,15(5)：295-297.
[58]Jung SY, Lim SM, Albertorio F et al. The Vroman effect:a molecular level description of fibrinogen displacement[J]. J Am Chem Soc,2003,125(42):12782-12786.
[59]Turbill P, Beugeling T, Poot AA. Proteins involved in the Vroman effect during exposure of human blood plasma to glass and polyethylene[J]. Biomaterials,1996,17(13): 1279-1287.
[60]Scott CF. Mechanism of the participation of the contact system in the Vroman effect. Review and summary[J]. J Biomater Sci Polym Ed,1991,2(3):173-181.
[61]Hartmann H, Lubbers B, Casaretto M et al. Rapid quantification of C3a and C5a using a combination of chromatographic and immunoassay procedures[J]. J Immunol Methods, 1993,166(1):35-44.
[62]Pease JE, Barker MD. N-linked glycosylation of the C5a receptor[J]. Biochem Mol Biol Int,1993,31(4):719-726.
[63]Mery L, Boulay F. Evidence that the extracellular N-terminal domain of C5aR contains amino-acid residues crucial for C5abinding[J]. Eur J Haematol,1993,51(5):282-287.
[64]Gerard NP, Bao L, Xiao-Ping H et al. Human chemotaxis receptor genes cluster at 19q13.3-13.4. Characterization of the human C5a receptor gene[J].Biochemistry,1993, 32(5):1243-1250.
[65]Van Epps DE, Simpson SJ, Johnson R. Relationship of C5a receptor modulation to the functional responsiveness of human polymorphonuclear leukocytes to C5a[J]. J Immunol, 1993,150(1):246-252.
[66]Dobos GJ, Andre M, Bohler J et al. Inhibition of C5a-induced actin polymerization, chemotaxis, and phagocytosis of human polymorphonuclear neutrophils incubated in a glucose-based dialysis solution[J]. Adv Perit Dial,1993,9:307-311.
[67]Sluijter JP, Smeets MB, Velema E et al. Increase in collagen turnover but not in collagen fiber content is associated with flow-induced arterial remodeling[J]. J Vasc Res,2004, 41(6):546-555.
[68]Iba Y, Shibata A, Kato M et al. Possible involvement of mast cells in collagen remodeling in the late phase of cutaneous wound healing in mice[J]. Int Immunopharmacol,2004, 4(14):1873-1880.
[69]Kondo S, Kagami S, Urushihara M et al. Transforming growth factor-betal stimulates collagen matrix remodeling through increased adhesive and contractive potential by human renal fibroblasts[J]. Biochim Biophys Acta,2004,1693(2):91-100.
[70]Ferri N, Carragher NO, Raines EW. Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling:potential implications in atherosclerosis and lymphangioleiomyomatosis[J]. Am J Pathol,2004,164(5):1575-1585.
[71]Hurwitz C, Rosano CL, Peabody RA. Excretion of ultraviolet-absorbing material by leaky and non-leaky strains of Escherichia coli exposed to streptomycin[J]. Biochim Biophys Acta,1963,72:80-86.
[72]Szabo S, Istvan G. [Skin closure in inguinal hernia repair with rapidly absorbing Polyglactin 910/370 (Vicryl-Rapide) suture material][J]. Magy Seb,2002,55(2):77-80.
[73]Bornemisza G, Ladanyi J, Miko I. [Experimental skin replacement by means of absorbing alloplastic material][J]. Z Exp Chir,1976,9(3):150-154.
[74]Rausa L, Arena E, Gebbia N et al. On the possible causes of the release of material absorbing at 260 m-mu by streptomycin treated E. coli cells (K 12 and B)[J]. J Antibiot (Tokyo),1967,20(3):142-148.
[75]Taneli F, Aydede H, Vatansever S et al. The long-term effect of mesh bioprosthesis in inguinal hernia repair on testicular nitric oxide metabolism and apoptosis in rat testis[J]. Cell Biochem Funct,2005,23(3):213-220.
[76]Knight BC, Tait WF. Dacron patch infection following carotid endarterectomy:a systematic review of the literature [J]. Eur J Vasc Endovasc Surg,2009,37(2):140-148.
[77]Byer A, Keys RC, Panush D et al. Late infection of a Dacron carotid endarterectomy patch--a case report[J]. Vasc Surg,2001,35(6):469-472.
[78]Sternbergh WC,3rd. Regarding "Dacron carotid patch infection:a report of eight cases"[J]. J Vasc Surg,2001,33(3):663-664.
[79]Rizzo A, Hertzer NR, O'Hara P J et al. Dacron carotid patch infection:a report of eight cases[J]. J Vasc Surg,2000,32(3):602-606.
[80]Azad R, Mehta MR. Is the test patch useful in determining safety against operative infection?[J]. Indian J Ophthalmol,1989,37(1):20-23.
[81]Fourestier M. [Detection and prevention of tuberculous primary infection by use of tuberculin patch-tests and BCG-S (systematic) vaccinations in children of a large French city; Montreuil experiment,1948-1952.][J]. Acta Tuberc Belg,1954,45(3):305-319.
[82]Mukhopadhyay S, Gowtham S, Scheicher RH et al. Theoretical study of physisorption of nucleobases on boron nitride nanotubes:a new class of hybrid nano-biomaterials[J]. Nanotechnology,2010,21(16):165703.
[83]Tangpasuthadol V, Pendharkar SM, Peterson RC et al. Hydrolytic degradation of tyrosine-derived polycarbonates, a class of new biomaterials. Part II:3-yr study of polymeric devices[J]. Biomaterials,2000,21(23):2379-2387.
[84]Barbucci R, Magnani A, Baszkin A et al. Physico-chemical surface characterization of hyaluronic acid derivatives as a new class of biomaterials [J]. J Biomater Sci Polym Ed, 1993,4(3):245-273.
[85]Chirila TV, Thompson DE, Constable IJ. In vitro cytotoxicity of melanized poly (2-hydroxyethyl methacrylate) hydrogels, a novel class of ocular biomaterials[J]. J Biomater Sci Polym Ed,1992,3(6):481-498.
[86]de Souza VK, Harrowell P. Rigidity percolation and the spatial heterogeneity of soft modes in disordered materials [J]. Proc Natl Acad Sci USA,2009,106(36):15136-15141.
[87]Llorens J, Pera-Titus M. A thermodynamic analysis of gas adsorption on microporous materials:evaluation of energy heterogeneity[J]. J Colloid Interface Sci,2009,331(2): 302-311.
[88]Wassenaar LI, Hobson KA. Stable-hydrogen isotope heterogeneity in keratinous materials: mass spectrometry and migratory wildlife tissue subsampling strategies [J]. Rapid Commun Mass Spectrom,2006,20(16):2505-2510.
[89]Gritti F, Guiochon G. A chromatographic estimate of the degree of surface heterogeneity of RPLC packing materials.Ⅲ. Endcapped amido-embedded reversed phase[J]. J Chromatogr A,2006,1103(1):69-82.
[90]Marinenko R, Leigh S. Heterogeneity evaluation of research materials for microanalysis standards certification[J]. Microsc Microanal,2004,10(4):491-506.
[91]Pak Yu N, Vdovkin AV, Borodachyov AD. The effect of heterogeneity in gamma-ray albedo analysis of mineral raw materials[J]. Appl Radiat Isot,2001,54(3):509-517.
[92]Charnay C, Lagerge S, Partyka S. Assessment of the Surface Heterogeneity of Talc Materials[J]. J Colloid Interface Sci,2001,233(2):250-258.
[93]Taner T, Cima RR, Larson DW et al. The use of human acellular dermal matrix for parastomal hernia repair in patients with inflammatory bowel disease:a novel technique to repair fascial defects[J]. Dis Colon Rectum,2009,52(2):349-354.
[94]Roth JS, Dexter DD, Lumpkins K et al. Hydrated vs. freeze-dried human acellular dermal matrix for hernia repair:a comparison in a rabbit model[J]. Hernia,2009,13(2):201-207.
[95]Candage R, Jones K, Luchette FA et al. Use of human acellular dermal matrix for hernia repair:friend or foe?[J]. Surgery,2008,144(4):703-709; discussion 709-711.
[96]Milburn ML, Holton LH, Chung TL et al. Acellular dermal matrix compared with synthetic implant material for repair of ventral hernia in the setting of peri-operative Staphylococcus aureus implant contamination:a rabbit model[J]. Surg Infect (Larchmt), 2008,9(4):433-442.
[97]Blatnik J, Jin J, Rosen M. Abdominal hernia repair with bridging acellular dermal matrix--an expensive hernia sac[J]. Am J Surg,2008,196(1):47-50.
[98]Jin J, Rosen MJ, Blatnik J et al. Use of acellular dermal matrix for complicated ventral hernia repair:does technique affect outcomes?[J]. J Am Coll Surg,2007,205(5):654-660.
[99]Bruen K, Downey E. Successful repair of a diaphragmatic hernia through a pericardial window with acellular dermal matrix[J]. J Laparoendosc Adv Surg Tech A,2007,17(3): 383-386.
[100]Ringley CD, Bochkarev V, Ahmed SI et al. Laparoscopic hiatal hernia repair with human acellular dermal matrix patch:our initial experience [J]. Am J Surg,2006,192(6):767-772.
[101]Silverman RP, Li EN, Holton LH,3rd et al. Ventral hernia repair using allogenic acellular dermal matrix in a swine model[J]. Hernia,2004,8(4):336-342.
[102]Pennisi VR, Klabunde EH, Mc GM et al. The use of Marlex 50 in plastic and reconstructive surgery. Ⅱ. Clinical observations [J]. Plast Reconstr Surg Transplant Bull, 1962,30:254-262.
[103]Pennisi VR, Faggella RM, Jr., Ott BS et al. The use of Marlex 50 in plastic and reconstructive surgery. Ⅰ. Experimental observations [J]. Plast Reconstr Surg Transplant Bull,1962,30:247-253.
[104]Harrington OB, Beall AC, Jr., Morris GC, Jr. et al. Circumferential replacement of the trachea with Marlex mesh[J]. Am Surg,1962,28:217-223.
[105]Greenberg SD, Beall AC, Jr., Wallace SA. Tracheal prosthesis:an experimental study with Marlex[J].Exp MolPathol,1962,1:141-150.
[106]Beall AC, Jr., Harrington OB, Greenberg SD et al. Tracheal replacement with heavy Marlex mesh. Circumferential replacement of the cervical trachea[J]. Arch Surg,1962,84: 390-396.
[107]Usher FC. Hernia repair with Marlex mesh. An analysis of 541 cases[J]. Arch Surg,1962, 84:325-328.
[108]Ferrara R, Imperiale S, Polato R et al. Abdominal incisional hernia repair. Intraperitoneal prosthetic technique using Bard Kugel Composix Mesh[J]. Chir Ital,2007,59(5): 735-742.
[109]Licheri S, Erdas E, Pomata M et al. Femoral hernia repair with Bard Mesh Dart Plug[J]. Chir Ital,2004,56(5):705-710.
[110]Kelly SE, Ehlers J, Llovera I et al. Comparison of tissue reaction to nylon and prolene sutures in rabbit iris and cornea[J]. Ophthalmic Surg,1975,6(4):105-110.
[111]Gao M, Han J, Tian J et al. Vypro II mesh for inguinal hernia repair:a meta analysis of randomized controlled trials[J]. Ann Surg,2010,251(5):838-842.
[112]Lim YN, Muller R, Corstiaans A et al. A long-term review of posterior colporrhaphy with Vypro 2 mesh[J]. Int Urogynecol J Pelvic Floor Dysfunct,2007,18(9):1053-1057.
[113]Puccio F, Solazzo M, Marciano P. Comparison of three different mesh materials in tension-free inguinal hernia repair:prolene versus Vypro versus surgisis[J]. Int Surg,2005, 90(3 Suppl):S21-23.
[114]Rosch R, Junge K, Quester R et al. Vypro II mesh in hernia repair:impact of polyglactin on long-term incorporation in rats[J]. Eur Surg Res,2003,35(5):445-450.
[115]Guidoin R, Levaillant PA, Marois M et al. [Polyethylene terephtalate (Dacron) prostheses as arterial substitutes. Value of commercial grafts as abdominal aorta substitutes in the dog (author's transl)][J]. J Mal Vasc,1980,5(1):3-12.
[116]Hazebroek EJ, Leibman S, Smith GS. Erosion of a composite PTFE/ePTFE mesh after hiatal hernia repair[J]. Surg Laparosc Endosc Percutan Tech,2009,19(2):175-177.
[117]Iannitti DA, Hope WW, Tsikitis V. Strength of tissue attachment to composite and ePTFE grafts after ventral hernia repair[J]. JSLS,2007,11(4):415-421.
[118]Huschitt N, Feller M, Lotspeich E et al. [Open intraperitoneal hernia repair for treatment of abdominal wall defects--early results by placement of a polypropylene-ePTFE-mesh][J]. Zentralbl Chir,2006,131(1):57-61.
[119]Koehler RH, Begos D, Berger D et al. Minimal adhesions to ePTFE mesh after laparoscopic ventral incisional hernia repair:reoperative findings in 65 cases[J]. Zentralbl Chir,2003,128(8):625-630.
[120]Gillion JF, Galy M, Jan C et al. [Repair of inguinal hernia by properitoneal positioning of an ePTFE soft patch (112 patches--75 patients)][J]. Ann Chir,1993,47(7):609-615.
[121]Amid PK, Shulman AG, Lichtenstein IL et al. Biomaterials for abdominal wall hernia surgery and principles of their applications [J]. Langenbecks Arch Chir,1994,379(3): 168-171.
[122]Maurice, Arregui, Abrahamson J et al. Abdominal Wall Hernias[M]. Berlin:Springer, 2001:170-282.
[123]J.Robert, Fitzgibbons, A G et al. Nyhus & CONDON'S Herrnia[J].5th edition,2001, Lippincolltt Williams Wilkins:170-282.
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |