动物性食品中兽药残留定量和确证分析关键技术研究
|
摘要
食品安全问题关系到国民的身体健康,已经成为人类共同关心的问题。兽药残留是影响动物性食品安全的主要原因之一,因此兽药残留分析方法是保障动物性食品安全的有效手段。兽药残留分析主要包括：样品前处理和分析检测技术两个方面。由于食品中兽药残留物水平低,样品基质复杂,使得复杂食品基质中兽药残留分析需要更为有效的前处理方法和灵敏的检测技术。目前,动物性食品中兽药残留定量和确证方法中存在的主要问题是：样品前处理方法,操作繁琐,耗时较长,试剂需要量大,同时分析药物种类少,提取样品的种类少。色谱分析方法,同时分离测定的药物种类少,检测灵敏度低,分离度差,基质干扰严重。因此,有必要对动物性食品中兽药残留定量和确证方法中样品前处理和色谱分析等关键技术进行研究。
本论文主要研究内容是：研究简便、快速、低廉和有效的样品前处理技术,研究快速、灵敏的多组分同时分析的液相色谱和色谱-质谱联用技术,用于动物性食品中兽药残留检测。本论文以糖皮质激素类、苯并咪唑类和机胂类药物为研究目标,探讨动物性食品中兽药残留定量和确证方法中的样品前处理技术和色谱分析技术,建立动物性食品中糖皮质激素类、苯并咪唑类和机胂类药物残留检测方法。本论文的研究,可以为动物性食品中兽药残留的检测研究提供技术支持和理论依据,对动物性食品安全评价也具有指导意义和参考价值。
1、动物性食品中糖皮质激素类药物多残留分析方法研究。
建立高效液相色谱-串联质谱(HPLC-MS/MS)检测猪、牛、羊肌肉和肝脏、鸡肌肉、鸡蛋和牛奶动物性食品中的糖皮质激素类药物方法(泼尼松、泼尼松龙、氢化可的松、地塞米松、倍他米松、氟氢可的松、甲基泼尼松、倍氯米松)。样品前处理采用碱水解,乙酸乙酯提取,硅胶固相柱萃取净化。采用碱水解,缩短了样品水解时间。采用硅胶固相萃取柱用于各种基质中糖皮质激素药物的萃取净化,简化了多种萃取柱多步净化的方法,样品操作简便,净化效果好。采用C18色谱柱,乙腈和水(0.2%甲酸)为流动相,成功地解决了地塞米松和倍他米松2种同分异构体分离的难题。质谱检测采用电喷雾离子源,多反应选择监测模式,方法具有灵敏度高,特异性好等特点。糖皮质激素类药物在肝脏中定量限为1.0μg/kg-4.0μg/kg,在牛奶中定量限为0.2μg/g-0.8μg/kg,在肌肉和鸡蛋中定量限为0.5μg/kg-2.0μg/kg。本方法已成功用于2008年北京奥运会动物性食品中糖皮质激素类药物监控。本方法简便、快速,适用于动物性食品中糖皮质激素类药物的定性和定量分析。
2、动物性食品中苯并咪唑类药物多残留分析方法研究
建立苯并咪唑类21种药物在猪、牛、羊、鸡肌肉和肝脏、鱼肌肉、鸡蛋和牛奶动物性食品中的高效液相色谱-紫外(HPLC-UV)和HPLC-MS/MS的定量和确证分析方法。样品前处理采用固相萃取技术和加速溶剂萃取技术,详细探讨了这两种提取净化技术的提取效果和影响因素。采用固相萃取净化,样品前处理简单,有机试剂用量少。采用快速溶剂萃取,样品前处理简便,快速,有机试剂用量少,可以实现自动化,减少有毒试剂对人体的污染。用固相萃取技术和加速溶剂萃取技术,解决了多种样品基质中,多种苯并咪唑类药物分析中的样品前处理技术的难题。采用C18色谱柱梯度洗脱,解决了21种苯并咪唑类药物采用HPLC测定时色谱分离的难题,建立了测定21种苯并咪唑类药物HPLC方法,在猪、牛、羊、鸡和鱼的肌肉、鸡蛋和牛奶中定量限为10gg/kg,猪、牛、羊和鸡肝脏中定量限为20μg/kg。优化了色谱和质谱参数,建立测定21种苯并咪唑类药物HPLC-MS/MS方法,在动物性食品中定量限为0.02μg/kg-0.5μg/kg,方法灵敏度高,特异性好。
3、动物性食品中有机胂类药物多残留分析方法研究
建立阿散酸、洛克沙胂、硝苯胂酸、卡巴胂4种有机胂类药物在猪、鸡肌肉和肝脏、鱼肌肉和鸡蛋动物性食品中的HPLC-UV和HPLC-MS/MS方法。样品前处理采用超声振荡萃取技术,以甲醇、乙腈和三氯乙酸混合溶液为提取剂,可以同时提取动物性食品中4种有机胂类药物；采用强阴离子交换(SAX)固相萃取柱净化,样品前处理简单,有机试剂用量少,基质干扰少。HPLC-UV方法采用Hypersil ODSC18色谱柱,乙腈和1%乙酸为流动相。HPLC-MS/MS方法采用HILIC Silica色谱柱,乙腈和乙酸铵为流动相。本方法采用HPLC-UV和HPLC-MS/MS同时测定动物源性食品中4种有机胂类药物,检测灵敏度高、特异性好。本方法可以广泛应用于动物源性食品中多种有机胂类药物的监测,对动物性食品中多残留分析方法研究具有指导意义,为动物性食品安全评价提供技术支持。
Food safety concerns everyone's health and has attracted more attention around the world. Veterinary drug residues in food of animal origin are one of the main impacts on food safety. Hence, the development of analysis methods for the determination of veterinary drugs residues in food is necessary to ensure food sasfety. There are two prominent problems in veterinary drug residues analysis, one is the pretreatment means, and the other is the separation and deterniantion method. Since the food matrices are complex and veterinary drug residues are of trace level, more effective sample pretreatment and sensitive determination method should mathch the requirement of the veterinary drug residues analsis in food. Hence, the study on the sample preparation technology and chromatographic analysis is crucial to determination of veterinary drug residues in food.
The main study content of this thesis was to develope the sample preparation technology and chromatographic analysis method to determine veterinary drugs residues in food. The main purpose of this thesis was to resolve the questions of sample preparation technology and chromatographic analysis, in order to esbilish methods for determination of residues of glucocorticoids, benzimidazoles and organic arsenic in food. The study provides technical and thesis support for controlling veterinary drug residues in food and evaluating on animal food safety.
1. Development of a method for simultaneous determination of residues of glucocorticoid in animal derived food.
A confirmatory and quantitative method using liquid chromatography-tandem mass spectrometry (LC-MS/MS) to determine the presence of eight glucocorticoids (prednisone, prednisolone, hydrocortisone, methylprednisolone, dexamethasone, betamethasone, beclomethasone, and fludrocortisone) in edible tissues of swine, cattle, sheep and chicken, egg and milk is described. After deconjugation in alkali media, samples were extracted with ethyl acetate for glucocorticoids followed by solid-phase extraction clean-up and reconstitution in the LC mobile phase. The hydrolysis procedure with sodium hydroxide was used to reduce handling time. A single-step solid-phase extraction method was optimized which is suitable for the clean-up of the compounds of interest in many diverse tissue matrices. LC separations were performed on a C18column with gradient elution using acetonitrile and water (containing0.2%formic acid) and the two epimers betamethasone and dexamethasone were successfully separated. LC-electrospray ionization (ESI)-MS/MS in negative mode with selected reaction monitoring (SRM) mode was performed to improve method sensitivity and reduce matrix interference. Two SRM transitions were used for each compound. The optimized procedure was successfully applied to monitor the food at the2008Summer Olympics Games in Beijing, China, demonstrating the method to be simple, fast, robust, and suitable for identification and quantification of glucocorticoids residues in foods of animal origin.
2. Development of a method for simultaneous determination of residues of benzimidazole and its metabolites in animal derived food.
A confirmatory and quantitative method using HPLC-UV and HPLC-MS/MS have been established for simultaneous determination benzimidazole and its metabolites in the muscles and livers of swine, cattle, sheep, and chicken, muscle of fish, eggs, and milk. Sample prepatation techniques including solid phase extraction, and accelerated solvent extraction (ASE) were applied in extracting benzimidazole and its metabolites in animal derived foods. The sample pretreatment has been simplified for using the ultrasonic extraction and solid phase extraction in the method. The volume of the organic solvent was decreased using the acceleratet solvent extraction method, avoiding the toxicity solvent using, and realizing sanple-handling automatism in the method. HPLC-UV analysis was performed on C18column eluted and applied to simultaneous determination benzimidazoles. HPLC-MS/MS analysis was performed on C18column eluted by a mobile phase of acetonitrile spiked with a buffer solution consisting of5mmol l-1formic ammonium, and the analytes were detected by LC-ESI-MS/MS in positive mode with selected reaction monitoring (SRM) mode. The method has been successfully applied to monitoring real samples containing benzimidazole and its metabolites, which demonstrated that it is a simple, fast and robust method, and could be used as a regulatory tool to determine the residues of benzimidazole and its metabolites in animal-origin foods.
3. Development of a method for simultaneous quantification of residues of organic arsenic in animal derived food.
HPLC-UV and HPLC-MS/MS have been established for simultaneous determination of4organic arsenic (arsanilic Acid, roxarsone, nitarsone, carbarsone) in the muscles and livers of swine and chicken, the muscle of fish and egg. And some conditions such as sample extraction, purification and sample solvent have been deeply investigated in this experiment. Samples were extracted with methanol-acetonitrile-trichloroacetic acid solution in an ultrasonic bath, and purified by solid phase extraction on strong anion exchanger cartridges. The sample pretreatment has been simplified for using the ultrasonic extraction and solid phase extraction in the method. The volume of the organic solvent was decreased using the sample pretreatment method. This simply and little contaminative method with the familiar materials can be applied on monitoring the use of multi-organic arsenic in animal food. The samples were analyzed on an Hypersil ODS C18liquid chromatography column using a gradient program with methanol and1%acetic acid by HPLC-UV. The samples were analyzed on a HILIC Silica liquid chromatography column using a gradient program with acetonitrile and ammonium acetate by HPLC-MS/MS with electrospary ionization method. HPLC-UV and HPLC-MS/MS have been firstly established for simultaneous determination of organic arsenic in animal dereived foods. The methods have good sensitivity, specificity, and which can be appilied to monitor the possible misuse of organic arsen residues in animal derived foods. The experiment can be taken as an instruction to do studies on analysis methods for determination of multi-residues in animal tissues and provide technical support for evaluation on animal food safety.
本论文主要研究内容是：研究简便、快速、低廉和有效的样品前处理技术,研究快速、灵敏的多组分同时分析的液相色谱和色谱-质谱联用技术,用于动物性食品中兽药残留检测。本论文以糖皮质激素类、苯并咪唑类和机胂类药物为研究目标,探讨动物性食品中兽药残留定量和确证方法中的样品前处理技术和色谱分析技术,建立动物性食品中糖皮质激素类、苯并咪唑类和机胂类药物残留检测方法。本论文的研究,可以为动物性食品中兽药残留的检测研究提供技术支持和理论依据,对动物性食品安全评价也具有指导意义和参考价值。
1、动物性食品中糖皮质激素类药物多残留分析方法研究。
建立高效液相色谱-串联质谱(HPLC-MS/MS)检测猪、牛、羊肌肉和肝脏、鸡肌肉、鸡蛋和牛奶动物性食品中的糖皮质激素类药物方法(泼尼松、泼尼松龙、氢化可的松、地塞米松、倍他米松、氟氢可的松、甲基泼尼松、倍氯米松)。样品前处理采用碱水解,乙酸乙酯提取,硅胶固相柱萃取净化。采用碱水解,缩短了样品水解时间。采用硅胶固相萃取柱用于各种基质中糖皮质激素药物的萃取净化,简化了多种萃取柱多步净化的方法,样品操作简便,净化效果好。采用C18色谱柱,乙腈和水(0.2%甲酸)为流动相,成功地解决了地塞米松和倍他米松2种同分异构体分离的难题。质谱检测采用电喷雾离子源,多反应选择监测模式,方法具有灵敏度高,特异性好等特点。糖皮质激素类药物在肝脏中定量限为1.0μg/kg-4.0μg/kg,在牛奶中定量限为0.2μg/g-0.8μg/kg,在肌肉和鸡蛋中定量限为0.5μg/kg-2.0μg/kg。本方法已成功用于2008年北京奥运会动物性食品中糖皮质激素类药物监控。本方法简便、快速,适用于动物性食品中糖皮质激素类药物的定性和定量分析。
2、动物性食品中苯并咪唑类药物多残留分析方法研究
建立苯并咪唑类21种药物在猪、牛、羊、鸡肌肉和肝脏、鱼肌肉、鸡蛋和牛奶动物性食品中的高效液相色谱-紫外(HPLC-UV)和HPLC-MS/MS的定量和确证分析方法。样品前处理采用固相萃取技术和加速溶剂萃取技术,详细探讨了这两种提取净化技术的提取效果和影响因素。采用固相萃取净化,样品前处理简单,有机试剂用量少。采用快速溶剂萃取,样品前处理简便,快速,有机试剂用量少,可以实现自动化,减少有毒试剂对人体的污染。用固相萃取技术和加速溶剂萃取技术,解决了多种样品基质中,多种苯并咪唑类药物分析中的样品前处理技术的难题。采用C18色谱柱梯度洗脱,解决了21种苯并咪唑类药物采用HPLC测定时色谱分离的难题,建立了测定21种苯并咪唑类药物HPLC方法,在猪、牛、羊、鸡和鱼的肌肉、鸡蛋和牛奶中定量限为10gg/kg,猪、牛、羊和鸡肝脏中定量限为20μg/kg。优化了色谱和质谱参数,建立测定21种苯并咪唑类药物HPLC-MS/MS方法,在动物性食品中定量限为0.02μg/kg-0.5μg/kg,方法灵敏度高,特异性好。
3、动物性食品中有机胂类药物多残留分析方法研究
建立阿散酸、洛克沙胂、硝苯胂酸、卡巴胂4种有机胂类药物在猪、鸡肌肉和肝脏、鱼肌肉和鸡蛋动物性食品中的HPLC-UV和HPLC-MS/MS方法。样品前处理采用超声振荡萃取技术,以甲醇、乙腈和三氯乙酸混合溶液为提取剂,可以同时提取动物性食品中4种有机胂类药物；采用强阴离子交换(SAX)固相萃取柱净化,样品前处理简单,有机试剂用量少,基质干扰少。HPLC-UV方法采用Hypersil ODSC18色谱柱,乙腈和1%乙酸为流动相。HPLC-MS/MS方法采用HILIC Silica色谱柱,乙腈和乙酸铵为流动相。本方法采用HPLC-UV和HPLC-MS/MS同时测定动物源性食品中4种有机胂类药物,检测灵敏度高、特异性好。本方法可以广泛应用于动物源性食品中多种有机胂类药物的监测,对动物性食品中多残留分析方法研究具有指导意义,为动物性食品安全评价提供技术支持。
Food safety concerns everyone's health and has attracted more attention around the world. Veterinary drug residues in food of animal origin are one of the main impacts on food safety. Hence, the development of analysis methods for the determination of veterinary drugs residues in food is necessary to ensure food sasfety. There are two prominent problems in veterinary drug residues analysis, one is the pretreatment means, and the other is the separation and deterniantion method. Since the food matrices are complex and veterinary drug residues are of trace level, more effective sample pretreatment and sensitive determination method should mathch the requirement of the veterinary drug residues analsis in food. Hence, the study on the sample preparation technology and chromatographic analysis is crucial to determination of veterinary drug residues in food.
The main study content of this thesis was to develope the sample preparation technology and chromatographic analysis method to determine veterinary drugs residues in food. The main purpose of this thesis was to resolve the questions of sample preparation technology and chromatographic analysis, in order to esbilish methods for determination of residues of glucocorticoids, benzimidazoles and organic arsenic in food. The study provides technical and thesis support for controlling veterinary drug residues in food and evaluating on animal food safety.
1. Development of a method for simultaneous determination of residues of glucocorticoid in animal derived food.
A confirmatory and quantitative method using liquid chromatography-tandem mass spectrometry (LC-MS/MS) to determine the presence of eight glucocorticoids (prednisone, prednisolone, hydrocortisone, methylprednisolone, dexamethasone, betamethasone, beclomethasone, and fludrocortisone) in edible tissues of swine, cattle, sheep and chicken, egg and milk is described. After deconjugation in alkali media, samples were extracted with ethyl acetate for glucocorticoids followed by solid-phase extraction clean-up and reconstitution in the LC mobile phase. The hydrolysis procedure with sodium hydroxide was used to reduce handling time. A single-step solid-phase extraction method was optimized which is suitable for the clean-up of the compounds of interest in many diverse tissue matrices. LC separations were performed on a C18column with gradient elution using acetonitrile and water (containing0.2%formic acid) and the two epimers betamethasone and dexamethasone were successfully separated. LC-electrospray ionization (ESI)-MS/MS in negative mode with selected reaction monitoring (SRM) mode was performed to improve method sensitivity and reduce matrix interference. Two SRM transitions were used for each compound. The optimized procedure was successfully applied to monitor the food at the2008Summer Olympics Games in Beijing, China, demonstrating the method to be simple, fast, robust, and suitable for identification and quantification of glucocorticoids residues in foods of animal origin.
2. Development of a method for simultaneous determination of residues of benzimidazole and its metabolites in animal derived food.
A confirmatory and quantitative method using HPLC-UV and HPLC-MS/MS have been established for simultaneous determination benzimidazole and its metabolites in the muscles and livers of swine, cattle, sheep, and chicken, muscle of fish, eggs, and milk. Sample prepatation techniques including solid phase extraction, and accelerated solvent extraction (ASE) were applied in extracting benzimidazole and its metabolites in animal derived foods. The sample pretreatment has been simplified for using the ultrasonic extraction and solid phase extraction in the method. The volume of the organic solvent was decreased using the acceleratet solvent extraction method, avoiding the toxicity solvent using, and realizing sanple-handling automatism in the method. HPLC-UV analysis was performed on C18column eluted and applied to simultaneous determination benzimidazoles. HPLC-MS/MS analysis was performed on C18column eluted by a mobile phase of acetonitrile spiked with a buffer solution consisting of5mmol l-1formic ammonium, and the analytes were detected by LC-ESI-MS/MS in positive mode with selected reaction monitoring (SRM) mode. The method has been successfully applied to monitoring real samples containing benzimidazole and its metabolites, which demonstrated that it is a simple, fast and robust method, and could be used as a regulatory tool to determine the residues of benzimidazole and its metabolites in animal-origin foods.
3. Development of a method for simultaneous quantification of residues of organic arsenic in animal derived food.
HPLC-UV and HPLC-MS/MS have been established for simultaneous determination of4organic arsenic (arsanilic Acid, roxarsone, nitarsone, carbarsone) in the muscles and livers of swine and chicken, the muscle of fish and egg. And some conditions such as sample extraction, purification and sample solvent have been deeply investigated in this experiment. Samples were extracted with methanol-acetonitrile-trichloroacetic acid solution in an ultrasonic bath, and purified by solid phase extraction on strong anion exchanger cartridges. The sample pretreatment has been simplified for using the ultrasonic extraction and solid phase extraction in the method. The volume of the organic solvent was decreased using the sample pretreatment method. This simply and little contaminative method with the familiar materials can be applied on monitoring the use of multi-organic arsenic in animal food. The samples were analyzed on an Hypersil ODS C18liquid chromatography column using a gradient program with methanol and1%acetic acid by HPLC-UV. The samples were analyzed on a HILIC Silica liquid chromatography column using a gradient program with acetonitrile and ammonium acetate by HPLC-MS/MS with electrospary ionization method. HPLC-UV and HPLC-MS/MS have been firstly established for simultaneous determination of organic arsenic in animal dereived foods. The methods have good sensitivity, specificity, and which can be appilied to monitor the possible misuse of organic arsen residues in animal derived foods. The experiment can be taken as an instruction to do studies on analysis methods for determination of multi-residues in animal tissues and provide technical support for evaluation on animal food safety.
引文
曹庆云,颜惜玲,周武艺,叶慧,管武太.高效液相色谱测定鸡肝中洛克沙砷的方法研究.应用化工,2005,34：10-13
郭效中,刘天余.有机砷制剂对畜禽营养作用的研究进展.饲料博览,1999,12：28-30
侯亚莉,徐飞,李海燕,周德刚,李晓薇,丁双阳.液相色谱-电喷雾串联四极杆质谱法同时测定牛肉中地塞米松、倍他米松和倍氯米松残留.中国农学通报,2008,24(1)：127-131
胡晓刚,李攻科.分子印迹技术在样品前处理中的应用.分析化学,2006,34(7)：1035-1041
李核,李攻科,张展霞.微波辅助萃取技术的进展,分析化学,2003,10：1261-1268
李俊锁,邱月明,王超.兽药残留分析.上海科技出版社,2002.
廖巧霞.洛克沙胂在养殖业中的应用.广东畜牧兽医科技,2005,30(4)：9-10
刘茂玲,张迎.饲用抗菌素有机胂制剂的毒性、排泄及残留问题的讨论.饲料研究,2000,7：28-29
吕斌,石丹,张江华.华中科技大学学报(医学版),2005,34(5)：639-643
严建刚,高峰.有机胂制剂在畜牧生产中的应用与对环境污染问题的探讨.饲料广角,2004(17)：11-13
杨永嘉,王国忠,王雷.高效液相色谱法测定洛克沙胂预混剂含量丰富的研究.中国兽药杂志,2001,35(6)：23-26
张素霞,沈建忠,丁双阳,沈张奇.牛肝中苯并咪唑类药物残留的高效液相色谱检测方法.中国兽药杂志,2005,39(6)：18-21
张素霞,李俊锁,钱传范.牛肌肉组织中苯并咪唑类药物的基质固相分散-高效液相色谱多残留分析法.中国兽医学报,2000,(11)：569-571
中华人民共和国农业部公告第235号.动物性食品中兽药最高残留限,2002
Agata K W, Andrzej W. Determination of robenidine in animal feeds by liquid chromatography coupled with diode-array detection and mass spectrometry after accelerated solvent extraction. Analytica Chimica Acta,2005,543:46-51
Akhtar M H, Croteau L G. Extraction of salinomycin from finished layers ration by microwave solvent extraction followed by liquid chromatography. Analyst,1996, 121:803-810
Antignac J P, Bizec B L, Monteau F, Poulain F, Andre F. Multi-residue extraction-purification procedure for corticosteroids in biological samples for efficient control of their misuse in livestock production. Journal of Chromatography B,2001,757:11-19
Arancibia V, Valderrama M, Rodriguez P, Hurtado F, Segura R. Quantitative extraction of sulfonamides in meats by supercritical methanol-modified carbon dioxide:A foray into real-world sampling. Journal of Separation Science,2003, 26(18):1710-1716
Arenas R V, Johnson N A. Liquid chromatographic fluorescence method for multiresidue determination of thiabendazole and 5-hydroxythiabendazole in milk. Journal of AOAC International,1995,78:642-646.
Aresta A, Calvano C D, Palmisano F, Zambonin C G. Determination of clenbuterol in human urine and serum by solid-phase microextraction coupled to liquid chromatography. Journal of Pharmaceutical and Biomedical Analysis,2008,47: 641-645
Arthur C L, Pawliszyn J. Application of reversal electron attachment for ultrasensitive detection of thermal electron-attaching molecules:carbon tetrachloride and nitrobenzene. Analitical Chemistry,1990,62:2145-2151
Baiocchi C, Brussino M, Pazzi M, Medana C, Marini C, Genta E. Separation and determination of synthetic corticosteroids in bovine liver by LC-Ion-Trap-MS-MS on porous graphite. Chromatographia,2003,58:11-14
Balizs G. Determination of benzimidazole residues using liquid chromatography and tandem mass spectrometry. Journal of Chromatography B,1999,727:167-177.
Barker S A, McDowell T, Charkhian B, Hsieh L C, Short C R. Methodology for the analysis of benzimidazole anthelmintics as drug residues in animal tissues. Journal of Assoc Off Analitical Chemistry,1990,73:22-25
Barker S A. Matrix solid-phase dispersion. Journal of Chromatography A,2000,885: 115-121
Benetti C, Piro R, Binato G, Angeletti R, Biancotto G. Simultaneous determination of lincomycin and five macrolide antibiotic residues in honey by liquid chromatography coupled to electrospray ionization mass spectrometry (LC-MS/MS). Food Additived and Contaminants,2006,23:1099-1108
Blanchflower W J, Cannavan A, Kennedy D G. Determination of fenbendazole and oxfendazole in liver and muscle using liquid chromatography-mass spectrometry. Analyst,119,1994:1325-1328
Bogialli S, Coradazzi C, Di Corcia A, Lagana A, Sergi M. A rapid method based on hot water extraction and liquid chromatography-tandem mass spectrometry for analyzing tetracycline antibiotic residues in cheese. Journal of AOAC international,2007,90: 864-871
Brandon D L, Binder R G, Bates A H, Montague W C.A monoclonal antibody-based ELISA for thiabendazole in liver. Journal of Agricultural and Food Chemistry,1992, 40:1722-1726
Cannavan A, Hagan S A, Kennedy D G. Simultaneous determination of thiabendazole and its majormetabolite,5-hydroxy thiabendazole, in bovine tissues using gradient. Journal of Chromatography B,1998,718:103-113
Carpinteiro J, Quintana J B, Rodr'iguez I, Carro A M, Lorenzo R A, Cela R. Applicability of solid-phase microextraction followed by on-fiber silylation for the determination of estrogens in water samples by gas chromatography-tandem mass spectrometry. Journal of Chromatography A,2004,1056:179-185
Carr R A, Caille G, Ngoc A H, Foster R T. Stereo specific highperformance liquid chromatography assay of ketoprofen in human plasma and urine. Journal of Chromatography B,1995,668:175-181
Chen K L, Chiou P S. Oral treatment of mule ducks with arsenicals for inducing fatty liver. Poultry Science,2001,80:295-301
Chen S H, Wu S M, Wu H L. Stereochemical analysis of betamethasone and dexamethasone by derivatization and high-performance liquid chromatography. Journal of Chromatography,1992,595:203-208
Chen Y C, Hung Y P, Fleckenstein L. Liquid chromatographic assay of moxidectin in human plasma for application to pharmacokinetic studies. Journal of Pharmaceutical and Biomedical Analysis,2002,29:917
Cherlet M, Baere S D, Croubels S, Backer P D. Quantitative determination of dexamethasone in bovine plasma and tissues by liquid hromatography-atmospheric pressure chemical ionization-tandem mass spectrometry to monitor residue depletion kinetics. Analytica Chimica Acta,2005, 529:361-369
Chu P S, Wang R Y, Brandt T A, Weerasinghe C A. Determination of albendazole-2-aminosulfone in bovine milk using high-performance liquid chromatography with fluorometric detection. Journal of Chromatography,1993,620: 129-135
Commission Regulation (EC), No 1181/2002 of 1 July 2002 L (172):13. Off. Journal of European Communities COUNCIL REGULATION (EEC) No 2377/90.1990,6
Cooper A D, Shepherd M J. Evaluation of a novel immunoaffinity phase for the purification of cattle liver extracts prior to high-performance liquid chromatographic determination of β-agonists. Food and Agricultural Immunology,1996,8(3): 205-213
Courtheyn D, Vercammen J, Logghe M, Seghers H, De Wasch K, De Brabander H. Determination of betamethasone and triamcinolone acetonide by GC-NCI-MS in excreta of treated animals and development of a fast oxidation procedure for derivatisation of corticosteroids. Analyst,1998,123:2409-2414
Creaser C S, Feely S J, Houghton E, Seymour M. Immunoaffinity chromatography combined on-line with high-performance liquid chromatography-mass spectrometry for the determination of corticosteroids. Journal of Chromatography A,1998,794: 37-43
Croes K, Goeyens L, Baeyens W, Van Loco J, Impens S. Optimization and validation of a liquid chromatography tandem mass spectrometry (LC/MSn) method for analysis of corticosteroids in bovine liver:Evaluation of Keyhole Limpet (3-glucuronidase/sulfatase enzyme extract. Journal of Chromatography B,2009 877: 635-644
Croteau L G, Akhtar M H, Belanger J M R, Pare J R J. High Performance Liquid Chromatography Determination Following Microwave Assisted Extraction of 3-Nitro-4-Hydroxyphenylarsonic Acid from Swine Liver, Kidney, and Muscle. Journal of Liquid Chromatography & Related Technologies,1994,17:2971-2981
Danaher M, O'Keeffe M, Glennon J D. Extraction and isolation of avermectins and milbemycins from liver samples using unmodified supercritical CO2 with in-line trapping on basic alumina. Journal of Chromatography B,2001,761(1):115-123.
Danaher M, Keeffe M O, Glennon J D. Development and optimisation of a method for the extraction of benzimidazoles from animal liver using supercritical carbon dioxide. Analytica Chimica Acta,2003,483:313-324
De Ruyck H, Daeseleire E, De Ridder H, Van Renterghem R. Development and validation of a liquid chromatographic-electrospray tandem mass spectrometric multiresidue method for anthelmintics in milk. Journal of Chromatography A,2002, 976:181-194
De Ruyck H, Daeseleire E, Grijspeerdt K, De Ridder H, Van Renterghem B R, Huyghebaert G. Determination of flubendazole and its metabolites in eggs and poultry muscle with liquid chromatography-tandem mass spectrometry. Journal of Agricultural and Food Chemistry,2001,49:610-617
De Ruyck H, De Ridder H. Determination of tetracycline antibiotics in cow's milk by liquid chromatography/tandem mass spectrometry. Rapid Communications Mass Spectrometry,2007,21:1511-1520
De Ruyck H, Van Renterghem R, De Ridder H, De Brabander D. Determination of anthelmintic residues in milk by high performance liquid chromatography. Food Control,2000,11:165-173
Dean J R, Ebdon L, Foulkes M E, Crews H M, Massey R C. Determination of the growth promoter,4-hydroxy-3-nitrophenyl-arsonic acid in chicken tissue by coupled high-performance liquid chromatography-inductively coupled plasma mass spectrometry. Journal of Analysis At Spectroment,1994,9:615-618
Delahaut P, Jacquemin P, Colemonts Y, Dubois M, De Graeve J, Deluyker H. Quantitative determination of several synthetic corticosteroids by gas chromatography-mass spectrometry after purification by immunoaffinity chromatography. Journal of Chromatography B,1997,696:203-215
Delatour P, Debroye J, Lorgue G, Courtot D. Record Medical Veterrinary,1977,153:639
Delatour P, Lorgue G, Courtot D, Lapras M. Bull. Social. Sci. Vet. Med. Comp,1975,77: 197
Desi E, Kovacs A, Palotai Z, Kende A. Analysis of dexamethasone and prednisolone residues in bovine milk using matrix solid phase dispersion-liquid chromatography with ultraviolet detection. Microchemical Journal,2008,89 (1):77-81
Di Sabatino M, Di Pietra A M, Benfenati L, Di Simone B. Determination of 10 sulfonamide residues in meat samples by liquid chromatography with ultraviolet detection. Journal of AOAC International,2007,90:598-603
Dowling G, Cantwell H, Keeffe M O, Smyth M R. Multi-residue method for the determination of benzimidazoles in bovine liver. Analytica Chimica Acta,2005,529: 285-292
Draisci R, Marchiafava C, Palleschi L, Cammarata P, Cavalli S. Accelerated solvent extraction and liquid chromatography-tandem mass spectrometry quantitation of corticosteroid residues in bovine liver. Journal of Chromatography B,2001,753: 217-223
Dubois M, Fluchard D, Sior E, Delahaut Ph. Identification and quantification of five macrolide antibiotics in several tissues, eggs and milk by liquid chromatography-electrospray tandem mass spectrometry. Journal of Chromatography B,2001,753:189-202
Duchate J P, Beduin J M, Jauniau T X, Coignoul F, Vindevogel H. Glucocorticoids as doping agents in homing pigeons. Annales de Medecine Veterinaire,1993,137: 557-564
Dufresne G, Fouquet A, Forsyth D, Tittlemier S A. Multiresidue determination of quinolone and fluoroquinolone antibiotics in fish and shrimp by liquid chromatography/tandem mass spectrometry. Journal of AOAC International,2007, 90:604-612
Edmonds M S, Baker D H. Toxic effects of supplemental copper and roxarsone when fed alone or in combination to young pigs. Journal of Animal Science,1986,63(2): 533-537
EU Commission Decision 2002/657/EC of 12 August 2002, implementing Council Directive (EC) 96/23 concerning the performance of analytical methods and the interpretation of the results (txt with EEA relevance). Off J Eur Commun L221 (2002)8
Fagerquist C K, Lightfield A R, Lehotay S J. Confirmatory and quantitative analysis of beta-lactam antibiotics in bovine kidney tissue by dispersive solid-phase extraction and liquid chromatography-tandem mass spectrometry. Analitical Chemistry,2005, 77:1473-1482
Fan Y, Feng Y Q, Da Sh L, Wang Zh H. In-tube solid phase microextraction using a β-cyclodextrin coated capillary coupled to high performance liquid chromatography for determination of non-steroidal anti-inflammatory drugs in urine samples. Talanta, 2005,65:111-117
Fletouris D J, Botsoglou N A, Psomas I E, Mantis A I. Determination of the marker residue of albendazole in milk using ion-pair liquid chromatography and fluorescence detection. Analytica Chimica Acta,1997,345:111-119
Fletouris D J, Botsoglou N A, Psomas I E, Mantis A I. Rapid quantitative screening assay of trace benzimidazole residues in milk by liquid chromatography. Journal of AOAC International,1996a,79:1281-1287
Fletouris D J, Botsoglou N A, Psomas I E, Mantis A I. Trace analysis of albendazole and its sulphoxide and sulphone metabolites in milk by liquid chromatography. Journal of Chromatography B,1996b,687:427-435
Fletouris D J, Papapanagiotou E P, Nakos D S, Psomas I E. Highly sensitive ion pair liquid chromatographic determination of albendazole marker residue in animal tissues. Journal of Agricultural Food Chemistry,2005,53(4):893-898.
Florin M M, Ines de Lannoyb, Brad G, Janusz P. Blood sampling without blood draws for in vivo pharmacokinetic studies in rats. Journal of Pharmaceutical and Biomedical Analysis,2008,47:907-912
Fluri K, Rivier L, Dienes-Nagy A, You C H, Ma'itre A, Schweizer C, Saugy M, Mangin P. Method for confirmation of synthetic corticosteroids in doping urine samples by liquid chromatography-electrospray ionisation mass spectrometry. Journal of Chromatography A,2001,926:87-95
Fontanals N, Marce R M, Borull F. New hydrophilic materials for solid-phase extraction. Trends Analitical Chemistry,2005,24:394-399
Frerichs V A, Tornatore K M. Determination of the glucocorticoids prednisone, prednisolone, dexamethasone and cortisol in human serum using liquid chromatography coupled to tandem mass spectrometry. Journal of Chromatography B,2004,802:329-338
Greschonig H, Schmid MG, Gubitz G. Capillary electrophoretic separation of inorganic and organic arsenic compounds. Fresenius Journal Analysis Chemistry,1998,362: 218-223
Hajee C A J, Haagsma N. Liquid chromatographic determination of mebendazole and its metabolites, aminomebendazole and hydroxymebendazole, in eel muscle tissue. Journal of AOAC International,1996,79:645-651
Halko R, Padron S C, Sosa F Z, Santana R. Determination of benzimidazole fungicides in soil samples using microwave-assisted micellar extraction and liquid chromatography with fluorescence detection. Journal of AOAC International,2006, 89:1403-1409
Hegstad S,(?)iestad E L, Johansen U, Christophersen A S. Determination of benzodiazepines in human urine using solid-phase extraction and high-performance liquid chromatography-electrospray ionization tandem mass spectrometry. Journal of Analitical Toxicol,2006,30:31-37
Hernando M D, Go'mez M J, Agu" era A, Ferna'ndez-Alba A R. LC-MS analysis of basic pharmaceuticals (beta-blockers and anti-ulcer agents) in waste water and surface water. Trends Analitical Chemistry,2007,26:581-589
Herranz S, Moreno-Bondi M C, Marazuela M D. Development of a new pretreatment procedure based on pressurized liquid extraction for the determination of fluoroquinolone residues in table eggs. Journal of Chromatography A,2007,1140: 63-70
Herrero M, Cifuentes A, Ibanez E. Optimization of the Extraction of Antioxidants from Dunaliella salina Microalga by Pressurized Liquids. Journal of Agriculture Food Chemistry,2006,54:5597-5603
Hilton M J, Thomas K V. Determination of selected human pharmaceutical compounds in effluent and surface water samples by high-performance liquid chromatography-electrospray tandem mass spectrometry. Journal of Chromatography A,2003,1015:129-136
Ho E N M, Leung D K K, Wan T S M, Yu N H. Comprehensive screening of anabolic steroids, corticosteroids, and acidic drugs in horse urine by solid-phase extraction and liquid chromatography-mass spectrometry. Journal of Chromatography A,2006, 1120:38-53
Ho T S, Pedersen-Bjergaard S, Rasmussen K E. Recovery, enrichment and selectivity in liquid-phase microextraction Comparison with conventional liquid-liquid extraction Journal of Chromatography A,2002,963:3
Ho T S, Vasskog T, Anderssen T, Jensen E, Rasmussen E K, Pedersen-Bjergaard S. Analytica Chimica Acta,2007,592:1-8
Hu X, Pan J, Hu Y, Huo Y, Li G. Preparation and evaluation of solid-phase microextraction fiber based on molecularly imprinted polymers for trace analysis of tetracyclines in complicated samples. Journal of Chromatography A,2008,1188: 97-107
Iglesias Y, Fente C, Mayo S, Vazquez B, Francoa C, Cepeda A. Chemiluminescence detection of nine corticosteroids in liver. Analyst,2000,125:2071-2074
Iglesias Y, Fente C A, Vazquez B, Franco C, Cepeda A. Determination of dexamethasone in bovine liver by chemiluminescence high-performance liquid chromatography. Journal of Agricultural and Food Chemistry,1999,47:4275-4279
Iosifidou E, Shearan P, O'Keeffe M. Application of the matrix solid phase dispersion technique for the determination of ivermectin residues in fish muscle tissue. The Analyst,1994,119,2227-2229
Ito Y, Ikai Y, Okaa Ho, Matsumotoa H, Kagamia T, Takeba K. Application of ion-exchange cartridge clean-up in food analysis Ⅲ. Determination of benzylpenicillin, phenoxymethyl-penicillin, oxacillin, cloxacillin, nafcillin and dicloxacillin in bovine liver and kidney by liquid chromatography with ultraviolet detection. Journal of Chromatography A,2000,880:85-91
Jacobsen A M, Halling-Sorensen B, Ingerslev F, Hansen S H. Simultaneous extraction of tetracycline, macrolide and sulfonamide antibiotics from agricultural soils using pressurised liquid extraction, followed by solid-phase extraction and liquid chromatography-tandem mass spectrometry.. Journal of Chromatography A,2004, 1038:157-170
Jeannot M A, Cantwell F F. Solvent Microextraction into a Single Drop. Analytical Chemistry,1996,68(13):2236-2240
Jedziniak P, Szprengier-Juszkiewicz T, Olejnik M. Determination of benzimidazoles and levamisole residues in milk by liquid chromatography-mass spectrometry:screening method development and validation. Journal of Chromatography A,2009, 1216(46):8165-72.
Jia X, Shao B, Wu Y, Yang Y, Zhang J. Simultaneous determination of tetracylines and-quinolones antibiotics in egg by ultra-performance liquid chromatography-electrospray tandem mass spectrometry. Journal of AOAC International,2008,91:461-468
Jonsson J A, Lovkvist P, Audunsson G, NilveG. Mass transfer kinetics for analytical enrichment and sample preparation using supported liquid membranes in a flow system with stagnant acceptor liquid. Analytica Chimica Acta,1993,277:9-15
Keegan J, Whelan M, Danaher M, Crooks S, Sayers R, Anastasio A, Elliott C, Brandon D, Furey A, O'Kennedy R. Benzimidazole carbamate residues in milk:Detection by Surface Plasmon Resonance-biosensor, using a modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) method for extraction. Analytica Chimica Acta, 2009,654(2):111-9
Kennedy S, Rice D A, Cush P F. Neuropathology of experimental 3-nitro-4-hydroxyphenylarsonic acid toxicosis in pigs. Veterinary Patholog,1986, 23(4):454-61
Kinsella B, Lehotay S J, Mastovska K, Lightfield A R, Furey A, Danaher M. New method for the analysis of flukicide and other anthelmintic residues in bovine milk and liver using liquid chromatography-tandem mass spectrometry. Analytica Chimica Acta, 2009,637(1-2):196-207
Kureckova K, Maralikova B, Ventura K. Supercritical fluid extraction of steroids from biological samples and first experience with solid-phase microextraction-liquid chromatography. Journal of Chromatography B,2002,770:83-89
Lang Q, Wai C M. Supercritical fluid extraction in herbal and natural product studies-a practical review. Talanta,2001,53:771-782
Li C, Wu YL, Yang T, Zhang Y. Rapid simultaneous determination of dexamethasone and betamethasone in milk by liquid chromatography tandem mass spectrometry with isotope dilution. Journal of Chromatography A,2010,1217:411-414
Li J S, Li X W, Hu H B. Immunoaffinity column cleanup procedure for analysis of ivermectin in swine liver. Journal of Chromatography B,1997,696:166-171
Li J S, Li X W, Yuan J X, et al. Determination of sulfonamides in swine meat by immunoaffinity chromatography. Journal of AOAC International,2000,83:830-836
Lindsey M E, Meyer M, Thurman E M. Analysis of trace levels of sulfonamide and tetracycline antimicrobials in groundwater and surface water using solid-phase extraction and liquid chromatography/mass spectrometry. Analitical Chemistry,2001, 73:4640-4648
Long A R, Hsieh L C, Bello A C, Malbrough M S, Short C R, Barker S A. Method for the isolation and liquid chromatographic determination of chloramphenicol in milk. Journal of Agriciculture Food Chemistry,1990a,38:427-429
Long A R, Hsieh L C, Malbrough M S, Short C R, Barker S A. Matrix solid phase dispersion (MSPD) isolation and liquid chromatographic determination of furazolidone in pork muscle tissue. Journal of Assoc Off Analitical Chemistry,1991, 74:292-294
Long A R, Malbrough M, Hsieh L C. Methodology for the analysis of benzimidazole anthelmintics as drug residues in animal tissues. Journal of Assoc Off Analitical Chemistry,1990b,73:22-28
Magard M A, Berg H E B, Tagesson V. Determination of androstenone in pig fat using supercritical fluid extraction and gas chromatography-mass spectrometry. Journal of Agriculture Food Chemistry,1995,43:114-120
Malone E M, Dowling G, Elliott C T, Kennedy D G, Regan L. Development of a rapid, multi-class method for the confirmatory analysis of anti-inflammatory drugs in bovine milk using liquid chromatography tandem mass spectrometry. Journal of Chromatography A,2009,1216:8132-8140.
Mandal V, Mohan Y, Hemalatha S. Microwave assisted extraction-an innovative and promising extraction tool for medicinal plant research. Phrmacognosy Reviews,2007, 1:7-17
Marc C, Siegrid D B, Patrick D B. Quantitative determination of dexamethasone in bovine milk by liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry. Journal of Chromatography B,2004,805: 57-65
Marti A M, Mooser A E, Koch H. Determination of benzimidazole anthelmintics in meat samples. Journal of Chromatography,1990,498:145-157
Masque N, Marce R M, Borrull F, Comack P A G, Sherrington D C. Synthesis and evaluation of a molecularly imprinted polymer for selective on-line solid-phase extraction of 4-nitrophenol from environmental water. Analitical Chemistry,2002, 72:4122-4126
Matabudul D K, Crosby N T, Sumar S. A new and rapid method for the determination of nicarbazin residues in poultry feed, eggs and muscle tissue using supercritical fluid extraction and high performance liquid chromatography. The Analyst,1999,4: 499-502
McDonald M, Granelli K, Sjoberg P. Rapid multi-residue method for the quantitative determination and confirmation of glucocorticosteroids in bovine milk using liquid chromatography-electrospray ionization-tandem mass spectrometry. Analytica Chimica Acta,2007,588 (1):20-25
Fuh M R S, Chu S Y. Quantitative determination of sulfonamide in meat by solid-phase extraction and capillary electrophoresis. Analytica Chimica Acta,2003,499: 215-221
Mitani K, Fujioka M, Kataoka H. Fully automated analysis of estrogens in environmental waters by in-tube solid-phase microextraction coupled with liquid chromatography-tandem mass spectrometry. Journal of Chromatography A,2005, 1081:218-224
Mitani K, Kataoka H. Determination of fluoroquinolones in environmental waters by in-tube solid-phase microextraction coupled with liquid chromatography-tandem mass spectrometry. Analytica Chimica Acta,2006,562:16-22
Moreno L, Imperiale F, Mottier L, Alvarez L, Lanusse C. Comparison of milk residue profiles after oral and subcutaneous administration of benzimidazole anthelmintics to dairy cows. Analytica Chimica Acta,2005,536:91-99
Msagati T A, Nindi M M. Comparative study of sample preparation methods; supported liquid membrane and solid phase extraction in the determination of benzimidazole anthelmintics in biological matrices by liquid chromatography-electrospray-mass spectrometry. Talanta,2006,69(1):243-50
Msagati T A M, Nindi M M. Determination of β-lactam residues in foodstuffs of animal origin using supported liquid membrane extraction and liquid chromatography-mass spectrometry. Food Chemistry,2007,100:836-844
Negro A, Alvarez-Bujidos M L, Ortiz A I, Cubria J C, Mendez R, Ordonez D. Reversed-phase ion-pair high-performance liquid chromatographic determination of triclabendazole metabolites in serum and urine. Journal of Chromatogr,1992,576: 135-141
Noben J P, Gielen B, Royachers E, Missotten M, Jacobs A, Raus J. A high-performance liquid chromatography/tandem mass spectrometric screening method for eight synthetic corticosteroids in bovine feces and the simultaneous differentiation between dexamethasone and betamethasone. Journal of Rapid Communication Mass Spectrometry,2002,16:1590-1594
Nozaki O. Steroid analysis for medical diagnosis. Journal of Chromatography A,2001, 935:267-278
O'Keeffe M J, Martin S, Regan L. Validation of a multiresidue liquid chromatography-tandem mass spectrometric method for the quantitation and confirmation of corticosteroid residues in urine, according to the proposed SANCO 1085 criteria for banned substances. Analytica Chimica Acta,2003,483:341-350
Pedersen-Bjergaard S, Rasmussen K E. Liquid-liquid microextraction for sample preparation of biological fluids prior to capillary electrophoresis. Analitical Chemistry,1999,71:2650-2665
Pensabene J W, Fiddler W, Donoghue D J. Isolation of chloramphenicol from whole eggs by supercritical fluid extraction with in-line collection. Journal of AOAC International,1999,82:1334-1339
Pensabene J W, Fiddler W, Parks O W. Isolation of sulfonamides from whole egg by supercritical fluid extraction. Journal of Chromatography Science,1997,35: 270-274
Pergantis A S, Cullen R W, Chow T D, Igendor K G. Liquid chromatography and mass spectrometry for the speciation of arsenic animal feed additivies. Journal of Chromatogsaphy A,1997,764:211-222
Petrovic M, Gros M, Barcelo D. Multi-residue analysis of pharmaceuticals in wastewater by ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry. Journal of Chromatography A,2006,1124:68-81
Popp P, Bauer C, Wennrich L. Application of stir bar sorptive extraction in combination with column liquid chromatography for the determination of polycyclic aromatic hydrocarbons in water samples. Analitical Chimica Acta,2001,436:1-7
Psillakis E, Kalogerakid N. Developments in liquid-phase microextraction. Trends in Analytical Chemistry,2003,22:565-574
Renzo B, Vittorio R, Maurizio Z, Anselmo S, Flora L, Alberto B, Roberto F. Analysis of dexamethasone and betamethasone in bovine urine by purification with an on-line immunoaffinity chromatography-high-performance liquid chromatography system and determination by gas chromatography-mass spectrometry. Analytical Biochemistry,1996,235:119-126
Robert E Sapp, Sandra Davidson. Determination of roxarsone in feeds using solid phase extraction and liquid chromatography with ultraviolet detection. Journal of AOAC International,1993,76(5):956-961
Roerdink R A, Aldstadt H J. Sensitive method for the determination of roxarsone using solid-phasemicroextraction with multi-detector gas chromatography. Journal of Chromatography A,2004,1057:177-183
Rummel N, Shaikh B. Determination of albendazole and its metabolites in the muscle tissue of hybrid striped and largemouth bass using liquid chromatography with fluorescence detection. Journal ofAOAC Intternational.2008,91(2):469-477.
Ruyck H D, Daeseleire E, Ridder H D, Renterghem R V. Liquid chromatographic-electrospray tandem mass spectrometric method for the determination of mebendazole and its hydrolysed and reduced metabolites in sheep muscle. Analytica Chimica Acta,2003,483:111-123
Schenck F J, Barker S A, Long A R. Matrix solid-phase dispersion extraction and liquid chromatographic determination of ivermectin in bovine livertissue. Journal ofAOAC International 1992,75:655-662
Schlusener M P, Spiteller M, Bester K. Determination of antibiotics from soil by pressurized liquid extraction and liquid chromatography-tandem mass spectrometry. Journal of Chromatogr A,2003,1003:21-28
Sewram V, Raynor M W, Raidoo D M. and Mulholland D A. Coupling SFE to uterotonic bioassay:an on-line approach to analysing medicinal plants. Journal of Pharmaceutical and Biomedical Analysis,1998,18(3):305-318
Shaikh B, Rummel N, Reimschuessel R. Determination of albendazole and its major metabolites in the muscle tissues of atlantic salmon, tilapia, and rainbow trout by high performance liquid chromatography with fluorometric detection. Journal of Agricultural and Food Chemistry,2003,51:3254-3259
Shao B, Cui X, Yang Y, Zhang J, Wu Y.2009. Validation of a solid-phase extraction and ultra-performance liquid chromatographic tandem mass spectrometric method for the detection of 16 glucocorticoids in pig tissues. Journal of AOAC International,2009, 92:604-611
Shao B, Jia X, Wu Y, Hu J, Tu X, Zhang J. Multi-class confirmatory method for analyzing trace levels of tetracyline and quinolone antibiotics in pig tissues by ultra-performance liquid chromatography coupled with tandem mass spectrometry. Rapid Commun Mass Spectrom,2007,21:3487-3496
Shearan P, O Keeffe M, Smyth M R. Reversed-phase high-performance liquid chromatographic determination of dexamethasone in bovine tissues. Analyst,1991, 116:1365-1368
Shim J H, Shen J Y, Kim M R, Lee C J, Kim I S. Determination of the fluoroquinolone enrofloxacin in edible chicken muscle by supercritical fluid extraction and liquid chromatography with fluorescence detection. Journal of Agriculture Food Chemistry, 2003,51:7528-7532
Smith R M. Before the injection-modern methods of sample preparation forseparation techniques. Journal of Chromatography A,2003,1000:3-27
Steven A. Barker. Matrix solid-phase dispersion. Journal of Chromatography A,2000, 885:115-127
Stolker A A M, Van Ginkel L A. Stephany R W. Supercritical fluid extraction of methyltestosterone, nortestosterone and testosterone at low ppb levels from fortified bovine urine. Journal of Chromatography,1999,726:121-129
Stolker A A, Zoontjes P W, Schwillens P L, Kootstra P R, van Ginkel L A, Stephany R W, Brinkman U A. Determination of acetyl gestagenic steroids in kidney fat by automated supercritical fluid extraction and liquid chromatography ion-trap mass spectrometry. The Analyst,2002,127:748-754
Stolker A A, Zoontjes P W, van Ginkel L A. The use of supercritical fluid extraction for the determination of steroids in animal tissues. The Analyst,1998,123:2671-2676
Su S C, Chang C L, Chang P C, Chou S S. Simultaneous determination of albendazole, thiabendazole, mebendazole and their metabolites in livestock by high performance liquid chromatography. Journal of Food and drug ananlysis,2003,11:307-311
Tai S.S.-C, Cargile N, Barnes C J. Determination of thiabendazole, 5-hydroxythiabendazole, fenbendazole, and oxfendazole in milk. Journal of the Association of Official Analytical Chemists,1990,73:368-373
Takeba K, Fujinuma K, Sakamoto M, Miyazaki T, Oka H, Itoh Y, Nakazawa H. Simultaneous determination of triclabendazole and its sulphoxide and sulphone metabolites in bovine milk by high-performance liquid chromatography. Journal of Chromatography A,2000,882:99-107
Tang P W, Law W C, Terence S M W. Analysis of corticosteroids in equine urine by liquid chromatography-mass spectrometry. Journal of Chromatography B,2001, 754:229-244
Titus A M M, Mathew M N. Determination of β-lactam residues in foodstuffs of animal origin using supported liquid membrane extraction and liquid chromatography-mass spectrometry. Food Chemistry,2007,100:836-844
Tuomola M, Hakala M, Manninenl, Weigel P S, Kallenborn R, Hiihnerfuss H. Simultaneous solid-phase extraction of acidic, neutral and basic pharmaceuticals from aqueous samples at ambient (neutral) pH and their determination by gas chromatography-mass spectrometry. Journal of Chromatography A,2004,1023: 183-188
Valerie A. Frerichs, Kathleen M. Tornatore. Determination of the glucocorticoids prednisone, prednisolone, dexamethasone, and cortisol in human serum using liquid chromatography coupled to tandem mass spectrometry. Journal of Chromatography B,2004,802:329-338
Van de Water C, Haagsma N. Determination of chloramphenicol in swine muscle tissue using a monoclonal antibody-mediated clean-up procedure. Journal of Chromatography,1987,411:415-421
Van de Water C, Tebbal D, Haagsma N. Monoclonal antibody-mediated clean-up procedure for the high-performance liquid chromato graphic analysis of chloramphenicol in milk and eggs. Journal of Chromatography,1989,478(1): 205-215
Van den Hauwe O, Castro P J, Claereboudt J, Van peteghem C. Simultaneous determination of betamethasone and dexamethasone residues in bovine liver by liquid chromatography/tandem mass spectrometry. Rapid Communication in Mass Spectrometry,2001,15:857-861
Van den hauwe O, Dumoulin F, Antignac J P, Bouche M P, Elliott C, Van Peteghem C. Liquid chromatographic-mass spectrometric analysis of 11 glucocorticoid residues and an optimization of enzymatic hydrolysis conditions in bovine liver. Analytica Chimica Acta,2002,473:127-134
Van den hauwe O, Dumoulin F, Elliott C, Van Peteghem C. Detection of synthetic glucocorticoid residues in cattle tissue and hair samples after a single dose administration using LC-MS/MS. Journal of Chromatography B,2005,817: 215-223
Van G L A, Stephany R W, Rossum H J. Multi-immunoaffinity chromatography:A simple and highly selective clean-up method for multi-anabolic residue analysis of meat. Journal of Chromatography,1989,489:111-119
Volmer D A, Hui J P M. Rapid determination of corticosteroids in urine by combined solid phase microextraction/liquid chromatography/mass spectrometry. Rapid Communication in Mass Spectrometrry,1997,11:1926-1934
Walker L V, Walsh J R, Webber J J. High-performance liquid chromatography of sulphonamides extracted from bovine and porcine muscle by solid-phase dispersion. Journal of Chromatography,1992,595:179-184
Walsh J R, Walker L V, Webber J J. Determination of tetracyclines in bovine and porcine muscle by high-performance liquid chromatography using solid-phase extraction. Journal of Chromatography,1992,596:211-216
Wen Y, Zhou B S, Xu Y, Jin S W, Feng Y Q. Analysis of estrogens in environmental waters using polymer monolith in-polyether ether ketone tube solid-phase microextraction combined with high-performance liquid chromatography. Journal of Chromatography A,2006,113:21-28
Wershaw R L, Rutherford D W, Rostad C E, Garbarin J R., Ferrer I, Kennedy K R, Momplaisi G M, Grange A. Mass spectrometric identification of an azobenzene derivative produced by smectite-catalyzed conversion of 3-amino-4-hydroxyphenylarsonic acid. Talanta,2003,59:1219-1226
Wilson R T, Groneck J S, Henry A C, Rowe L R. Multiresidue assay for benzimidazole anthelmintics by liquid chromatography and confirmation by gas chromatography/selected-ion monitoring electron impact mass spectrometry. Journal of AOAC International,1991,74:56-67
Wise O R, Hartley W J. The toxic effects of roxarsone on turkey. Research of Veterinary Science,1974,16:336-340
Wu J C, Mester Z, Pawliszyn J. Speciation of organoarsenic compounds by polypyrrole-coated capillary in-tube solid phase microextraction coupled with liquid chromatography/electrospray ionization mass spectrometry. Analytica Chimica Acta,2000,424:211-222
Wu Z, Li J, Zhu L, Luo H, Xu X. Multi-residue analysis of avermectins in swine liver by immunoaffinity extraction and liquid chromatography-mass spectrometry. Journal of Chromatography B,2001,755:361-369
Yang S, Carlson K H. Solid-phase extraction high performance liquid chromatography-ion trap mass spectrometry for analysis of trace concentrations of macrolide antibiotics in natural and waste water matrices. Journal of Chromatography A,2004a,1038:141-155
Yang S, Cha J, Carlson K. Quantitative determination of trace concentrations of tetracycline and sulfonamide antibiotics in surface water using solid-phase extraction and liquid chromatography/ion trap tandem mass spectrometry. Rapid Communications in Mass Spectrometry,2004b,18:2131-2145
Yang S, Cha J, Carlson K. Simultaneous extraction and analysis of 11 tetracycline and sulfonamide antibiotics in influent and effluent domestic wastewater by solid-phase extraction and liquid chromatography-electrospray ionization tandem mass spectrometry. Journal of Chromatography A,2005,1097:40-53
Zhai Z D, Luo X P, Wu X M, Zhang H, Shi Y P, Chen L R, Li Y M. Analytical and semipreparative resolution of enatiomers of albendazole sulfoxide by HPLC on amylose tris (3,5-dimethylphenylcarbamate) chiral stationary phases. Journal of Biochemical and Biophysical Methods,2005,62:69-79
Zhang L, Wang Z, Chang B, Yang W. Determination of apramycin in animal feeds by solid-phase extraction and liquid chromatography with precolumn derivatization and fluorescence detection. Journal of AOAC International,2007,90:885-891
Zhang M, Wei F, Zhang Y F, Nie J, Feng Y Q. Novel polymer monolith microextraction using a poly (methacrylic acid-ethyl ene glycol dimethacrylate) monolith and its application to simultaneous analysis of several angiotensin Ⅱ receptor antagonists in human urine by capillary zone electrophoresis. Journal of Cromatography A,2006, 1102:294-231
Zhang Z, Yang M J, Yang M J, Pawliszyn. Solid phase microextraction. Journal of Analitical Chemistry,1994,66:844-849
Zhao H X, Wang L P, Qiu Y M, Zhou Z Q; Li X, Zhong W K. Simultaneous determination of three residual barbiturates in pork using accelerated solvent extraction and gas chromatography-mass spectrometr. Journal of Chromatography B, 2006,840:139-145
Zou Q H, Wang J, Wang X F, Liu Y, Han J, Hou F, Xie M X. Application of matrix solid-phase dispersion and high-performance liquid chromatography for determination of sulfonamides in honey. Journal of AOAC Intternational,2008,91: 252-257
Zougagh M, Valca'rcel M, Ri'os A. Supercritical fluid extraction:a critical review of its analytical usefulness. Trends Analitical Chemistry,2004,23:399-411
Zougagh M, Rios A. Supercritical fluid extraction of macrocyclic lactone mycotoxins in maize flour samples for rapid amperometric screening and alternative liquid chromatographic method for confirmation. Journal of Chromatography A,2008,1177: 50-57
郭效中,刘天余.有机砷制剂对畜禽营养作用的研究进展.饲料博览,1999,12：28-30
侯亚莉,徐飞,李海燕,周德刚,李晓薇,丁双阳.液相色谱-电喷雾串联四极杆质谱法同时测定牛肉中地塞米松、倍他米松和倍氯米松残留.中国农学通报,2008,24(1)：127-131
胡晓刚,李攻科.分子印迹技术在样品前处理中的应用.分析化学,2006,34(7)：1035-1041
李核,李攻科,张展霞.微波辅助萃取技术的进展,分析化学,2003,10：1261-1268
李俊锁,邱月明,王超.兽药残留分析.上海科技出版社,2002.
廖巧霞.洛克沙胂在养殖业中的应用.广东畜牧兽医科技,2005,30(4)：9-10
刘茂玲,张迎.饲用抗菌素有机胂制剂的毒性、排泄及残留问题的讨论.饲料研究,2000,7：28-29
吕斌,石丹,张江华.华中科技大学学报(医学版),2005,34(5)：639-643
严建刚,高峰.有机胂制剂在畜牧生产中的应用与对环境污染问题的探讨.饲料广角,2004(17)：11-13
杨永嘉,王国忠,王雷.高效液相色谱法测定洛克沙胂预混剂含量丰富的研究.中国兽药杂志,2001,35(6)：23-26
张素霞,沈建忠,丁双阳,沈张奇.牛肝中苯并咪唑类药物残留的高效液相色谱检测方法.中国兽药杂志,2005,39(6)：18-21
张素霞,李俊锁,钱传范.牛肌肉组织中苯并咪唑类药物的基质固相分散-高效液相色谱多残留分析法.中国兽医学报,2000,(11)：569-571
中华人民共和国农业部公告第235号.动物性食品中兽药最高残留限,2002
Agata K W, Andrzej W. Determination of robenidine in animal feeds by liquid chromatography coupled with diode-array detection and mass spectrometry after accelerated solvent extraction. Analytica Chimica Acta,2005,543:46-51
Akhtar M H, Croteau L G. Extraction of salinomycin from finished layers ration by microwave solvent extraction followed by liquid chromatography. Analyst,1996, 121:803-810
Antignac J P, Bizec B L, Monteau F, Poulain F, Andre F. Multi-residue extraction-purification procedure for corticosteroids in biological samples for efficient control of their misuse in livestock production. Journal of Chromatography B,2001,757:11-19
Arancibia V, Valderrama M, Rodriguez P, Hurtado F, Segura R. Quantitative extraction of sulfonamides in meats by supercritical methanol-modified carbon dioxide:A foray into real-world sampling. Journal of Separation Science,2003, 26(18):1710-1716
Arenas R V, Johnson N A. Liquid chromatographic fluorescence method for multiresidue determination of thiabendazole and 5-hydroxythiabendazole in milk. Journal of AOAC International,1995,78:642-646.
Aresta A, Calvano C D, Palmisano F, Zambonin C G. Determination of clenbuterol in human urine and serum by solid-phase microextraction coupled to liquid chromatography. Journal of Pharmaceutical and Biomedical Analysis,2008,47: 641-645
Arthur C L, Pawliszyn J. Application of reversal electron attachment for ultrasensitive detection of thermal electron-attaching molecules:carbon tetrachloride and nitrobenzene. Analitical Chemistry,1990,62:2145-2151
Baiocchi C, Brussino M, Pazzi M, Medana C, Marini C, Genta E. Separation and determination of synthetic corticosteroids in bovine liver by LC-Ion-Trap-MS-MS on porous graphite. Chromatographia,2003,58:11-14
Balizs G. Determination of benzimidazole residues using liquid chromatography and tandem mass spectrometry. Journal of Chromatography B,1999,727:167-177.
Barker S A, McDowell T, Charkhian B, Hsieh L C, Short C R. Methodology for the analysis of benzimidazole anthelmintics as drug residues in animal tissues. Journal of Assoc Off Analitical Chemistry,1990,73:22-25
Barker S A. Matrix solid-phase dispersion. Journal of Chromatography A,2000,885: 115-121
Benetti C, Piro R, Binato G, Angeletti R, Biancotto G. Simultaneous determination of lincomycin and five macrolide antibiotic residues in honey by liquid chromatography coupled to electrospray ionization mass spectrometry (LC-MS/MS). Food Additived and Contaminants,2006,23:1099-1108
Blanchflower W J, Cannavan A, Kennedy D G. Determination of fenbendazole and oxfendazole in liver and muscle using liquid chromatography-mass spectrometry. Analyst,119,1994:1325-1328
Bogialli S, Coradazzi C, Di Corcia A, Lagana A, Sergi M. A rapid method based on hot water extraction and liquid chromatography-tandem mass spectrometry for analyzing tetracycline antibiotic residues in cheese. Journal of AOAC international,2007,90: 864-871
Brandon D L, Binder R G, Bates A H, Montague W C.A monoclonal antibody-based ELISA for thiabendazole in liver. Journal of Agricultural and Food Chemistry,1992, 40:1722-1726
Cannavan A, Hagan S A, Kennedy D G. Simultaneous determination of thiabendazole and its majormetabolite,5-hydroxy thiabendazole, in bovine tissues using gradient. Journal of Chromatography B,1998,718:103-113
Carpinteiro J, Quintana J B, Rodr'iguez I, Carro A M, Lorenzo R A, Cela R. Applicability of solid-phase microextraction followed by on-fiber silylation for the determination of estrogens in water samples by gas chromatography-tandem mass spectrometry. Journal of Chromatography A,2004,1056:179-185
Carr R A, Caille G, Ngoc A H, Foster R T. Stereo specific highperformance liquid chromatography assay of ketoprofen in human plasma and urine. Journal of Chromatography B,1995,668:175-181
Chen K L, Chiou P S. Oral treatment of mule ducks with arsenicals for inducing fatty liver. Poultry Science,2001,80:295-301
Chen S H, Wu S M, Wu H L. Stereochemical analysis of betamethasone and dexamethasone by derivatization and high-performance liquid chromatography. Journal of Chromatography,1992,595:203-208
Chen Y C, Hung Y P, Fleckenstein L. Liquid chromatographic assay of moxidectin in human plasma for application to pharmacokinetic studies. Journal of Pharmaceutical and Biomedical Analysis,2002,29:917
Cherlet M, Baere S D, Croubels S, Backer P D. Quantitative determination of dexamethasone in bovine plasma and tissues by liquid hromatography-atmospheric pressure chemical ionization-tandem mass spectrometry to monitor residue depletion kinetics. Analytica Chimica Acta,2005, 529:361-369
Chu P S, Wang R Y, Brandt T A, Weerasinghe C A. Determination of albendazole-2-aminosulfone in bovine milk using high-performance liquid chromatography with fluorometric detection. Journal of Chromatography,1993,620: 129-135
Commission Regulation (EC), No 1181/2002 of 1 July 2002 L (172):13. Off. Journal of European Communities COUNCIL REGULATION (EEC) No 2377/90.1990,6
Cooper A D, Shepherd M J. Evaluation of a novel immunoaffinity phase for the purification of cattle liver extracts prior to high-performance liquid chromatographic determination of β-agonists. Food and Agricultural Immunology,1996,8(3): 205-213
Courtheyn D, Vercammen J, Logghe M, Seghers H, De Wasch K, De Brabander H. Determination of betamethasone and triamcinolone acetonide by GC-NCI-MS in excreta of treated animals and development of a fast oxidation procedure for derivatisation of corticosteroids. Analyst,1998,123:2409-2414
Creaser C S, Feely S J, Houghton E, Seymour M. Immunoaffinity chromatography combined on-line with high-performance liquid chromatography-mass spectrometry for the determination of corticosteroids. Journal of Chromatography A,1998,794: 37-43
Croes K, Goeyens L, Baeyens W, Van Loco J, Impens S. Optimization and validation of a liquid chromatography tandem mass spectrometry (LC/MSn) method for analysis of corticosteroids in bovine liver:Evaluation of Keyhole Limpet (3-glucuronidase/sulfatase enzyme extract. Journal of Chromatography B,2009 877: 635-644
Croteau L G, Akhtar M H, Belanger J M R, Pare J R J. High Performance Liquid Chromatography Determination Following Microwave Assisted Extraction of 3-Nitro-4-Hydroxyphenylarsonic Acid from Swine Liver, Kidney, and Muscle. Journal of Liquid Chromatography & Related Technologies,1994,17:2971-2981
Danaher M, O'Keeffe M, Glennon J D. Extraction and isolation of avermectins and milbemycins from liver samples using unmodified supercritical CO2 with in-line trapping on basic alumina. Journal of Chromatography B,2001,761(1):115-123.
Danaher M, Keeffe M O, Glennon J D. Development and optimisation of a method for the extraction of benzimidazoles from animal liver using supercritical carbon dioxide. Analytica Chimica Acta,2003,483:313-324
De Ruyck H, Daeseleire E, De Ridder H, Van Renterghem R. Development and validation of a liquid chromatographic-electrospray tandem mass spectrometric multiresidue method for anthelmintics in milk. Journal of Chromatography A,2002, 976:181-194
De Ruyck H, Daeseleire E, Grijspeerdt K, De Ridder H, Van Renterghem B R, Huyghebaert G. Determination of flubendazole and its metabolites in eggs and poultry muscle with liquid chromatography-tandem mass spectrometry. Journal of Agricultural and Food Chemistry,2001,49:610-617
De Ruyck H, De Ridder H. Determination of tetracycline antibiotics in cow's milk by liquid chromatography/tandem mass spectrometry. Rapid Communications Mass Spectrometry,2007,21:1511-1520
De Ruyck H, Van Renterghem R, De Ridder H, De Brabander D. Determination of anthelmintic residues in milk by high performance liquid chromatography. Food Control,2000,11:165-173
Dean J R, Ebdon L, Foulkes M E, Crews H M, Massey R C. Determination of the growth promoter,4-hydroxy-3-nitrophenyl-arsonic acid in chicken tissue by coupled high-performance liquid chromatography-inductively coupled plasma mass spectrometry. Journal of Analysis At Spectroment,1994,9:615-618
Delahaut P, Jacquemin P, Colemonts Y, Dubois M, De Graeve J, Deluyker H. Quantitative determination of several synthetic corticosteroids by gas chromatography-mass spectrometry after purification by immunoaffinity chromatography. Journal of Chromatography B,1997,696:203-215
Delatour P, Debroye J, Lorgue G, Courtot D. Record Medical Veterrinary,1977,153:639
Delatour P, Lorgue G, Courtot D, Lapras M. Bull. Social. Sci. Vet. Med. Comp,1975,77: 197
Desi E, Kovacs A, Palotai Z, Kende A. Analysis of dexamethasone and prednisolone residues in bovine milk using matrix solid phase dispersion-liquid chromatography with ultraviolet detection. Microchemical Journal,2008,89 (1):77-81
Di Sabatino M, Di Pietra A M, Benfenati L, Di Simone B. Determination of 10 sulfonamide residues in meat samples by liquid chromatography with ultraviolet detection. Journal of AOAC International,2007,90:598-603
Dowling G, Cantwell H, Keeffe M O, Smyth M R. Multi-residue method for the determination of benzimidazoles in bovine liver. Analytica Chimica Acta,2005,529: 285-292
Draisci R, Marchiafava C, Palleschi L, Cammarata P, Cavalli S. Accelerated solvent extraction and liquid chromatography-tandem mass spectrometry quantitation of corticosteroid residues in bovine liver. Journal of Chromatography B,2001,753: 217-223
Dubois M, Fluchard D, Sior E, Delahaut Ph. Identification and quantification of five macrolide antibiotics in several tissues, eggs and milk by liquid chromatography-electrospray tandem mass spectrometry. Journal of Chromatography B,2001,753:189-202
Duchate J P, Beduin J M, Jauniau T X, Coignoul F, Vindevogel H. Glucocorticoids as doping agents in homing pigeons. Annales de Medecine Veterinaire,1993,137: 557-564
Dufresne G, Fouquet A, Forsyth D, Tittlemier S A. Multiresidue determination of quinolone and fluoroquinolone antibiotics in fish and shrimp by liquid chromatography/tandem mass spectrometry. Journal of AOAC International,2007, 90:604-612
Edmonds M S, Baker D H. Toxic effects of supplemental copper and roxarsone when fed alone or in combination to young pigs. Journal of Animal Science,1986,63(2): 533-537
EU Commission Decision 2002/657/EC of 12 August 2002, implementing Council Directive (EC) 96/23 concerning the performance of analytical methods and the interpretation of the results (txt with EEA relevance). Off J Eur Commun L221 (2002)8
Fagerquist C K, Lightfield A R, Lehotay S J. Confirmatory and quantitative analysis of beta-lactam antibiotics in bovine kidney tissue by dispersive solid-phase extraction and liquid chromatography-tandem mass spectrometry. Analitical Chemistry,2005, 77:1473-1482
Fan Y, Feng Y Q, Da Sh L, Wang Zh H. In-tube solid phase microextraction using a β-cyclodextrin coated capillary coupled to high performance liquid chromatography for determination of non-steroidal anti-inflammatory drugs in urine samples. Talanta, 2005,65:111-117
Fletouris D J, Botsoglou N A, Psomas I E, Mantis A I. Determination of the marker residue of albendazole in milk using ion-pair liquid chromatography and fluorescence detection. Analytica Chimica Acta,1997,345:111-119
Fletouris D J, Botsoglou N A, Psomas I E, Mantis A I. Rapid quantitative screening assay of trace benzimidazole residues in milk by liquid chromatography. Journal of AOAC International,1996a,79:1281-1287
Fletouris D J, Botsoglou N A, Psomas I E, Mantis A I. Trace analysis of albendazole and its sulphoxide and sulphone metabolites in milk by liquid chromatography. Journal of Chromatography B,1996b,687:427-435
Fletouris D J, Papapanagiotou E P, Nakos D S, Psomas I E. Highly sensitive ion pair liquid chromatographic determination of albendazole marker residue in animal tissues. Journal of Agricultural Food Chemistry,2005,53(4):893-898.
Florin M M, Ines de Lannoyb, Brad G, Janusz P. Blood sampling without blood draws for in vivo pharmacokinetic studies in rats. Journal of Pharmaceutical and Biomedical Analysis,2008,47:907-912
Fluri K, Rivier L, Dienes-Nagy A, You C H, Ma'itre A, Schweizer C, Saugy M, Mangin P. Method for confirmation of synthetic corticosteroids in doping urine samples by liquid chromatography-electrospray ionisation mass spectrometry. Journal of Chromatography A,2001,926:87-95
Fontanals N, Marce R M, Borull F. New hydrophilic materials for solid-phase extraction. Trends Analitical Chemistry,2005,24:394-399
Frerichs V A, Tornatore K M. Determination of the glucocorticoids prednisone, prednisolone, dexamethasone and cortisol in human serum using liquid chromatography coupled to tandem mass spectrometry. Journal of Chromatography B,2004,802:329-338
Greschonig H, Schmid MG, Gubitz G. Capillary electrophoretic separation of inorganic and organic arsenic compounds. Fresenius Journal Analysis Chemistry,1998,362: 218-223
Hajee C A J, Haagsma N. Liquid chromatographic determination of mebendazole and its metabolites, aminomebendazole and hydroxymebendazole, in eel muscle tissue. Journal of AOAC International,1996,79:645-651
Halko R, Padron S C, Sosa F Z, Santana R. Determination of benzimidazole fungicides in soil samples using microwave-assisted micellar extraction and liquid chromatography with fluorescence detection. Journal of AOAC International,2006, 89:1403-1409
Hegstad S,(?)iestad E L, Johansen U, Christophersen A S. Determination of benzodiazepines in human urine using solid-phase extraction and high-performance liquid chromatography-electrospray ionization tandem mass spectrometry. Journal of Analitical Toxicol,2006,30:31-37
Hernando M D, Go'mez M J, Agu" era A, Ferna'ndez-Alba A R. LC-MS analysis of basic pharmaceuticals (beta-blockers and anti-ulcer agents) in waste water and surface water. Trends Analitical Chemistry,2007,26:581-589
Herranz S, Moreno-Bondi M C, Marazuela M D. Development of a new pretreatment procedure based on pressurized liquid extraction for the determination of fluoroquinolone residues in table eggs. Journal of Chromatography A,2007,1140: 63-70
Herrero M, Cifuentes A, Ibanez E. Optimization of the Extraction of Antioxidants from Dunaliella salina Microalga by Pressurized Liquids. Journal of Agriculture Food Chemistry,2006,54:5597-5603
Hilton M J, Thomas K V. Determination of selected human pharmaceutical compounds in effluent and surface water samples by high-performance liquid chromatography-electrospray tandem mass spectrometry. Journal of Chromatography A,2003,1015:129-136
Ho E N M, Leung D K K, Wan T S M, Yu N H. Comprehensive screening of anabolic steroids, corticosteroids, and acidic drugs in horse urine by solid-phase extraction and liquid chromatography-mass spectrometry. Journal of Chromatography A,2006, 1120:38-53
Ho T S, Pedersen-Bjergaard S, Rasmussen K E. Recovery, enrichment and selectivity in liquid-phase microextraction Comparison with conventional liquid-liquid extraction Journal of Chromatography A,2002,963:3
Ho T S, Vasskog T, Anderssen T, Jensen E, Rasmussen E K, Pedersen-Bjergaard S. Analytica Chimica Acta,2007,592:1-8
Hu X, Pan J, Hu Y, Huo Y, Li G. Preparation and evaluation of solid-phase microextraction fiber based on molecularly imprinted polymers for trace analysis of tetracyclines in complicated samples. Journal of Chromatography A,2008,1188: 97-107
Iglesias Y, Fente C, Mayo S, Vazquez B, Francoa C, Cepeda A. Chemiluminescence detection of nine corticosteroids in liver. Analyst,2000,125:2071-2074
Iglesias Y, Fente C A, Vazquez B, Franco C, Cepeda A. Determination of dexamethasone in bovine liver by chemiluminescence high-performance liquid chromatography. Journal of Agricultural and Food Chemistry,1999,47:4275-4279
Iosifidou E, Shearan P, O'Keeffe M. Application of the matrix solid phase dispersion technique for the determination of ivermectin residues in fish muscle tissue. The Analyst,1994,119,2227-2229
Ito Y, Ikai Y, Okaa Ho, Matsumotoa H, Kagamia T, Takeba K. Application of ion-exchange cartridge clean-up in food analysis Ⅲ. Determination of benzylpenicillin, phenoxymethyl-penicillin, oxacillin, cloxacillin, nafcillin and dicloxacillin in bovine liver and kidney by liquid chromatography with ultraviolet detection. Journal of Chromatography A,2000,880:85-91
Jacobsen A M, Halling-Sorensen B, Ingerslev F, Hansen S H. Simultaneous extraction of tetracycline, macrolide and sulfonamide antibiotics from agricultural soils using pressurised liquid extraction, followed by solid-phase extraction and liquid chromatography-tandem mass spectrometry.. Journal of Chromatography A,2004, 1038:157-170
Jeannot M A, Cantwell F F. Solvent Microextraction into a Single Drop. Analytical Chemistry,1996,68(13):2236-2240
Jedziniak P, Szprengier-Juszkiewicz T, Olejnik M. Determination of benzimidazoles and levamisole residues in milk by liquid chromatography-mass spectrometry:screening method development and validation. Journal of Chromatography A,2009, 1216(46):8165-72.
Jia X, Shao B, Wu Y, Yang Y, Zhang J. Simultaneous determination of tetracylines and-quinolones antibiotics in egg by ultra-performance liquid chromatography-electrospray tandem mass spectrometry. Journal of AOAC International,2008,91:461-468
Jonsson J A, Lovkvist P, Audunsson G, NilveG. Mass transfer kinetics for analytical enrichment and sample preparation using supported liquid membranes in a flow system with stagnant acceptor liquid. Analytica Chimica Acta,1993,277:9-15
Keegan J, Whelan M, Danaher M, Crooks S, Sayers R, Anastasio A, Elliott C, Brandon D, Furey A, O'Kennedy R. Benzimidazole carbamate residues in milk:Detection by Surface Plasmon Resonance-biosensor, using a modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) method for extraction. Analytica Chimica Acta, 2009,654(2):111-9
Kennedy S, Rice D A, Cush P F. Neuropathology of experimental 3-nitro-4-hydroxyphenylarsonic acid toxicosis in pigs. Veterinary Patholog,1986, 23(4):454-61
Kinsella B, Lehotay S J, Mastovska K, Lightfield A R, Furey A, Danaher M. New method for the analysis of flukicide and other anthelmintic residues in bovine milk and liver using liquid chromatography-tandem mass spectrometry. Analytica Chimica Acta, 2009,637(1-2):196-207
Kureckova K, Maralikova B, Ventura K. Supercritical fluid extraction of steroids from biological samples and first experience with solid-phase microextraction-liquid chromatography. Journal of Chromatography B,2002,770:83-89
Lang Q, Wai C M. Supercritical fluid extraction in herbal and natural product studies-a practical review. Talanta,2001,53:771-782
Li C, Wu YL, Yang T, Zhang Y. Rapid simultaneous determination of dexamethasone and betamethasone in milk by liquid chromatography tandem mass spectrometry with isotope dilution. Journal of Chromatography A,2010,1217:411-414
Li J S, Li X W, Hu H B. Immunoaffinity column cleanup procedure for analysis of ivermectin in swine liver. Journal of Chromatography B,1997,696:166-171
Li J S, Li X W, Yuan J X, et al. Determination of sulfonamides in swine meat by immunoaffinity chromatography. Journal of AOAC International,2000,83:830-836
Lindsey M E, Meyer M, Thurman E M. Analysis of trace levels of sulfonamide and tetracycline antimicrobials in groundwater and surface water using solid-phase extraction and liquid chromatography/mass spectrometry. Analitical Chemistry,2001, 73:4640-4648
Long A R, Hsieh L C, Bello A C, Malbrough M S, Short C R, Barker S A. Method for the isolation and liquid chromatographic determination of chloramphenicol in milk. Journal of Agriciculture Food Chemistry,1990a,38:427-429
Long A R, Hsieh L C, Malbrough M S, Short C R, Barker S A. Matrix solid phase dispersion (MSPD) isolation and liquid chromatographic determination of furazolidone in pork muscle tissue. Journal of Assoc Off Analitical Chemistry,1991, 74:292-294
Long A R, Malbrough M, Hsieh L C. Methodology for the analysis of benzimidazole anthelmintics as drug residues in animal tissues. Journal of Assoc Off Analitical Chemistry,1990b,73:22-28
Magard M A, Berg H E B, Tagesson V. Determination of androstenone in pig fat using supercritical fluid extraction and gas chromatography-mass spectrometry. Journal of Agriculture Food Chemistry,1995,43:114-120
Malone E M, Dowling G, Elliott C T, Kennedy D G, Regan L. Development of a rapid, multi-class method for the confirmatory analysis of anti-inflammatory drugs in bovine milk using liquid chromatography tandem mass spectrometry. Journal of Chromatography A,2009,1216:8132-8140.
Mandal V, Mohan Y, Hemalatha S. Microwave assisted extraction-an innovative and promising extraction tool for medicinal plant research. Phrmacognosy Reviews,2007, 1:7-17
Marc C, Siegrid D B, Patrick D B. Quantitative determination of dexamethasone in bovine milk by liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry. Journal of Chromatography B,2004,805: 57-65
Marti A M, Mooser A E, Koch H. Determination of benzimidazole anthelmintics in meat samples. Journal of Chromatography,1990,498:145-157
Masque N, Marce R M, Borrull F, Comack P A G, Sherrington D C. Synthesis and evaluation of a molecularly imprinted polymer for selective on-line solid-phase extraction of 4-nitrophenol from environmental water. Analitical Chemistry,2002, 72:4122-4126
Matabudul D K, Crosby N T, Sumar S. A new and rapid method for the determination of nicarbazin residues in poultry feed, eggs and muscle tissue using supercritical fluid extraction and high performance liquid chromatography. The Analyst,1999,4: 499-502
McDonald M, Granelli K, Sjoberg P. Rapid multi-residue method for the quantitative determination and confirmation of glucocorticosteroids in bovine milk using liquid chromatography-electrospray ionization-tandem mass spectrometry. Analytica Chimica Acta,2007,588 (1):20-25
Fuh M R S, Chu S Y. Quantitative determination of sulfonamide in meat by solid-phase extraction and capillary electrophoresis. Analytica Chimica Acta,2003,499: 215-221
Mitani K, Fujioka M, Kataoka H. Fully automated analysis of estrogens in environmental waters by in-tube solid-phase microextraction coupled with liquid chromatography-tandem mass spectrometry. Journal of Chromatography A,2005, 1081:218-224
Mitani K, Kataoka H. Determination of fluoroquinolones in environmental waters by in-tube solid-phase microextraction coupled with liquid chromatography-tandem mass spectrometry. Analytica Chimica Acta,2006,562:16-22
Moreno L, Imperiale F, Mottier L, Alvarez L, Lanusse C. Comparison of milk residue profiles after oral and subcutaneous administration of benzimidazole anthelmintics to dairy cows. Analytica Chimica Acta,2005,536:91-99
Msagati T A, Nindi M M. Comparative study of sample preparation methods; supported liquid membrane and solid phase extraction in the determination of benzimidazole anthelmintics in biological matrices by liquid chromatography-electrospray-mass spectrometry. Talanta,2006,69(1):243-50
Msagati T A M, Nindi M M. Determination of β-lactam residues in foodstuffs of animal origin using supported liquid membrane extraction and liquid chromatography-mass spectrometry. Food Chemistry,2007,100:836-844
Negro A, Alvarez-Bujidos M L, Ortiz A I, Cubria J C, Mendez R, Ordonez D. Reversed-phase ion-pair high-performance liquid chromatographic determination of triclabendazole metabolites in serum and urine. Journal of Chromatogr,1992,576: 135-141
Noben J P, Gielen B, Royachers E, Missotten M, Jacobs A, Raus J. A high-performance liquid chromatography/tandem mass spectrometric screening method for eight synthetic corticosteroids in bovine feces and the simultaneous differentiation between dexamethasone and betamethasone. Journal of Rapid Communication Mass Spectrometry,2002,16:1590-1594
Nozaki O. Steroid analysis for medical diagnosis. Journal of Chromatography A,2001, 935:267-278
O'Keeffe M J, Martin S, Regan L. Validation of a multiresidue liquid chromatography-tandem mass spectrometric method for the quantitation and confirmation of corticosteroid residues in urine, according to the proposed SANCO 1085 criteria for banned substances. Analytica Chimica Acta,2003,483:341-350
Pedersen-Bjergaard S, Rasmussen K E. Liquid-liquid microextraction for sample preparation of biological fluids prior to capillary electrophoresis. Analitical Chemistry,1999,71:2650-2665
Pensabene J W, Fiddler W, Donoghue D J. Isolation of chloramphenicol from whole eggs by supercritical fluid extraction with in-line collection. Journal of AOAC International,1999,82:1334-1339
Pensabene J W, Fiddler W, Parks O W. Isolation of sulfonamides from whole egg by supercritical fluid extraction. Journal of Chromatography Science,1997,35: 270-274
Pergantis A S, Cullen R W, Chow T D, Igendor K G. Liquid chromatography and mass spectrometry for the speciation of arsenic animal feed additivies. Journal of Chromatogsaphy A,1997,764:211-222
Petrovic M, Gros M, Barcelo D. Multi-residue analysis of pharmaceuticals in wastewater by ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry. Journal of Chromatography A,2006,1124:68-81
Popp P, Bauer C, Wennrich L. Application of stir bar sorptive extraction in combination with column liquid chromatography for the determination of polycyclic aromatic hydrocarbons in water samples. Analitical Chimica Acta,2001,436:1-7
Psillakis E, Kalogerakid N. Developments in liquid-phase microextraction. Trends in Analytical Chemistry,2003,22:565-574
Renzo B, Vittorio R, Maurizio Z, Anselmo S, Flora L, Alberto B, Roberto F. Analysis of dexamethasone and betamethasone in bovine urine by purification with an on-line immunoaffinity chromatography-high-performance liquid chromatography system and determination by gas chromatography-mass spectrometry. Analytical Biochemistry,1996,235:119-126
Robert E Sapp, Sandra Davidson. Determination of roxarsone in feeds using solid phase extraction and liquid chromatography with ultraviolet detection. Journal of AOAC International,1993,76(5):956-961
Roerdink R A, Aldstadt H J. Sensitive method for the determination of roxarsone using solid-phasemicroextraction with multi-detector gas chromatography. Journal of Chromatography A,2004,1057:177-183
Rummel N, Shaikh B. Determination of albendazole and its metabolites in the muscle tissue of hybrid striped and largemouth bass using liquid chromatography with fluorescence detection. Journal ofAOAC Intternational.2008,91(2):469-477.
Ruyck H D, Daeseleire E, Ridder H D, Renterghem R V. Liquid chromatographic-electrospray tandem mass spectrometric method for the determination of mebendazole and its hydrolysed and reduced metabolites in sheep muscle. Analytica Chimica Acta,2003,483:111-123
Schenck F J, Barker S A, Long A R. Matrix solid-phase dispersion extraction and liquid chromatographic determination of ivermectin in bovine livertissue. Journal ofAOAC International 1992,75:655-662
Schlusener M P, Spiteller M, Bester K. Determination of antibiotics from soil by pressurized liquid extraction and liquid chromatography-tandem mass spectrometry. Journal of Chromatogr A,2003,1003:21-28
Sewram V, Raynor M W, Raidoo D M. and Mulholland D A. Coupling SFE to uterotonic bioassay:an on-line approach to analysing medicinal plants. Journal of Pharmaceutical and Biomedical Analysis,1998,18(3):305-318
Shaikh B, Rummel N, Reimschuessel R. Determination of albendazole and its major metabolites in the muscle tissues of atlantic salmon, tilapia, and rainbow trout by high performance liquid chromatography with fluorometric detection. Journal of Agricultural and Food Chemistry,2003,51:3254-3259
Shao B, Cui X, Yang Y, Zhang J, Wu Y.2009. Validation of a solid-phase extraction and ultra-performance liquid chromatographic tandem mass spectrometric method for the detection of 16 glucocorticoids in pig tissues. Journal of AOAC International,2009, 92:604-611
Shao B, Jia X, Wu Y, Hu J, Tu X, Zhang J. Multi-class confirmatory method for analyzing trace levels of tetracyline and quinolone antibiotics in pig tissues by ultra-performance liquid chromatography coupled with tandem mass spectrometry. Rapid Commun Mass Spectrom,2007,21:3487-3496
Shearan P, O Keeffe M, Smyth M R. Reversed-phase high-performance liquid chromatographic determination of dexamethasone in bovine tissues. Analyst,1991, 116:1365-1368
Shim J H, Shen J Y, Kim M R, Lee C J, Kim I S. Determination of the fluoroquinolone enrofloxacin in edible chicken muscle by supercritical fluid extraction and liquid chromatography with fluorescence detection. Journal of Agriculture Food Chemistry, 2003,51:7528-7532
Smith R M. Before the injection-modern methods of sample preparation forseparation techniques. Journal of Chromatography A,2003,1000:3-27
Steven A. Barker. Matrix solid-phase dispersion. Journal of Chromatography A,2000, 885:115-127
Stolker A A M, Van Ginkel L A. Stephany R W. Supercritical fluid extraction of methyltestosterone, nortestosterone and testosterone at low ppb levels from fortified bovine urine. Journal of Chromatography,1999,726:121-129
Stolker A A, Zoontjes P W, Schwillens P L, Kootstra P R, van Ginkel L A, Stephany R W, Brinkman U A. Determination of acetyl gestagenic steroids in kidney fat by automated supercritical fluid extraction and liquid chromatography ion-trap mass spectrometry. The Analyst,2002,127:748-754
Stolker A A, Zoontjes P W, van Ginkel L A. The use of supercritical fluid extraction for the determination of steroids in animal tissues. The Analyst,1998,123:2671-2676
Su S C, Chang C L, Chang P C, Chou S S. Simultaneous determination of albendazole, thiabendazole, mebendazole and their metabolites in livestock by high performance liquid chromatography. Journal of Food and drug ananlysis,2003,11:307-311
Tai S.S.-C, Cargile N, Barnes C J. Determination of thiabendazole, 5-hydroxythiabendazole, fenbendazole, and oxfendazole in milk. Journal of the Association of Official Analytical Chemists,1990,73:368-373
Takeba K, Fujinuma K, Sakamoto M, Miyazaki T, Oka H, Itoh Y, Nakazawa H. Simultaneous determination of triclabendazole and its sulphoxide and sulphone metabolites in bovine milk by high-performance liquid chromatography. Journal of Chromatography A,2000,882:99-107
Tang P W, Law W C, Terence S M W. Analysis of corticosteroids in equine urine by liquid chromatography-mass spectrometry. Journal of Chromatography B,2001, 754:229-244
Titus A M M, Mathew M N. Determination of β-lactam residues in foodstuffs of animal origin using supported liquid membrane extraction and liquid chromatography-mass spectrometry. Food Chemistry,2007,100:836-844
Tuomola M, Hakala M, Manninenl, Weigel P S, Kallenborn R, Hiihnerfuss H. Simultaneous solid-phase extraction of acidic, neutral and basic pharmaceuticals from aqueous samples at ambient (neutral) pH and their determination by gas chromatography-mass spectrometry. Journal of Chromatography A,2004,1023: 183-188
Valerie A. Frerichs, Kathleen M. Tornatore. Determination of the glucocorticoids prednisone, prednisolone, dexamethasone, and cortisol in human serum using liquid chromatography coupled to tandem mass spectrometry. Journal of Chromatography B,2004,802:329-338
Van de Water C, Haagsma N. Determination of chloramphenicol in swine muscle tissue using a monoclonal antibody-mediated clean-up procedure. Journal of Chromatography,1987,411:415-421
Van de Water C, Tebbal D, Haagsma N. Monoclonal antibody-mediated clean-up procedure for the high-performance liquid chromato graphic analysis of chloramphenicol in milk and eggs. Journal of Chromatography,1989,478(1): 205-215
Van den Hauwe O, Castro P J, Claereboudt J, Van peteghem C. Simultaneous determination of betamethasone and dexamethasone residues in bovine liver by liquid chromatography/tandem mass spectrometry. Rapid Communication in Mass Spectrometry,2001,15:857-861
Van den hauwe O, Dumoulin F, Antignac J P, Bouche M P, Elliott C, Van Peteghem C. Liquid chromatographic-mass spectrometric analysis of 11 glucocorticoid residues and an optimization of enzymatic hydrolysis conditions in bovine liver. Analytica Chimica Acta,2002,473:127-134
Van den hauwe O, Dumoulin F, Elliott C, Van Peteghem C. Detection of synthetic glucocorticoid residues in cattle tissue and hair samples after a single dose administration using LC-MS/MS. Journal of Chromatography B,2005,817: 215-223
Van G L A, Stephany R W, Rossum H J. Multi-immunoaffinity chromatography:A simple and highly selective clean-up method for multi-anabolic residue analysis of meat. Journal of Chromatography,1989,489:111-119
Volmer D A, Hui J P M. Rapid determination of corticosteroids in urine by combined solid phase microextraction/liquid chromatography/mass spectrometry. Rapid Communication in Mass Spectrometrry,1997,11:1926-1934
Walker L V, Walsh J R, Webber J J. High-performance liquid chromatography of sulphonamides extracted from bovine and porcine muscle by solid-phase dispersion. Journal of Chromatography,1992,595:179-184
Walsh J R, Walker L V, Webber J J. Determination of tetracyclines in bovine and porcine muscle by high-performance liquid chromatography using solid-phase extraction. Journal of Chromatography,1992,596:211-216
Wen Y, Zhou B S, Xu Y, Jin S W, Feng Y Q. Analysis of estrogens in environmental waters using polymer monolith in-polyether ether ketone tube solid-phase microextraction combined with high-performance liquid chromatography. Journal of Chromatography A,2006,113:21-28
Wershaw R L, Rutherford D W, Rostad C E, Garbarin J R., Ferrer I, Kennedy K R, Momplaisi G M, Grange A. Mass spectrometric identification of an azobenzene derivative produced by smectite-catalyzed conversion of 3-amino-4-hydroxyphenylarsonic acid. Talanta,2003,59:1219-1226
Wilson R T, Groneck J S, Henry A C, Rowe L R. Multiresidue assay for benzimidazole anthelmintics by liquid chromatography and confirmation by gas chromatography/selected-ion monitoring electron impact mass spectrometry. Journal of AOAC International,1991,74:56-67
Wise O R, Hartley W J. The toxic effects of roxarsone on turkey. Research of Veterinary Science,1974,16:336-340
Wu J C, Mester Z, Pawliszyn J. Speciation of organoarsenic compounds by polypyrrole-coated capillary in-tube solid phase microextraction coupled with liquid chromatography/electrospray ionization mass spectrometry. Analytica Chimica Acta,2000,424:211-222
Wu Z, Li J, Zhu L, Luo H, Xu X. Multi-residue analysis of avermectins in swine liver by immunoaffinity extraction and liquid chromatography-mass spectrometry. Journal of Chromatography B,2001,755:361-369
Yang S, Carlson K H. Solid-phase extraction high performance liquid chromatography-ion trap mass spectrometry for analysis of trace concentrations of macrolide antibiotics in natural and waste water matrices. Journal of Chromatography A,2004a,1038:141-155
Yang S, Cha J, Carlson K. Quantitative determination of trace concentrations of tetracycline and sulfonamide antibiotics in surface water using solid-phase extraction and liquid chromatography/ion trap tandem mass spectrometry. Rapid Communications in Mass Spectrometry,2004b,18:2131-2145
Yang S, Cha J, Carlson K. Simultaneous extraction and analysis of 11 tetracycline and sulfonamide antibiotics in influent and effluent domestic wastewater by solid-phase extraction and liquid chromatography-electrospray ionization tandem mass spectrometry. Journal of Chromatography A,2005,1097:40-53
Zhai Z D, Luo X P, Wu X M, Zhang H, Shi Y P, Chen L R, Li Y M. Analytical and semipreparative resolution of enatiomers of albendazole sulfoxide by HPLC on amylose tris (3,5-dimethylphenylcarbamate) chiral stationary phases. Journal of Biochemical and Biophysical Methods,2005,62:69-79
Zhang L, Wang Z, Chang B, Yang W. Determination of apramycin in animal feeds by solid-phase extraction and liquid chromatography with precolumn derivatization and fluorescence detection. Journal of AOAC International,2007,90:885-891
Zhang M, Wei F, Zhang Y F, Nie J, Feng Y Q. Novel polymer monolith microextraction using a poly (methacrylic acid-ethyl ene glycol dimethacrylate) monolith and its application to simultaneous analysis of several angiotensin Ⅱ receptor antagonists in human urine by capillary zone electrophoresis. Journal of Cromatography A,2006, 1102:294-231
Zhang Z, Yang M J, Yang M J, Pawliszyn. Solid phase microextraction. Journal of Analitical Chemistry,1994,66:844-849
Zhao H X, Wang L P, Qiu Y M, Zhou Z Q; Li X, Zhong W K. Simultaneous determination of three residual barbiturates in pork using accelerated solvent extraction and gas chromatography-mass spectrometr. Journal of Chromatography B, 2006,840:139-145
Zou Q H, Wang J, Wang X F, Liu Y, Han J, Hou F, Xie M X. Application of matrix solid-phase dispersion and high-performance liquid chromatography for determination of sulfonamides in honey. Journal of AOAC Intternational,2008,91: 252-257
Zougagh M, Valca'rcel M, Ri'os A. Supercritical fluid extraction:a critical review of its analytical usefulness. Trends Analitical Chemistry,2004,23:399-411
Zougagh M, Rios A. Supercritical fluid extraction of macrocyclic lactone mycotoxins in maize flour samples for rapid amperometric screening and alternative liquid chromatographic method for confirmation. Journal of Chromatography A,2008,1177: 50-57
© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号 地址：北京市海淀区学院路29号 邮编：100083 电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700 |