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从五脏相关理论探讨瞳神疾病典型眼底改变的证候特点
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摘要
目的:探讨瞳神疾病眼底改变与五脏之间的关系,以此揭示瞳神疾病眼底改变的证候特点。
     方法:研究病例主要来自两方面:一.回顾性研究:2005年1月-2009年12月就治于广州中医药大学第一附属医院眼科的住院病人,眼底表现为水肿、出血及渗出,通过全身辩证及方药确定五脏相关关系;二.前瞻性研究:2010年1月-2011年4月就治于广州中医药大学第一附属医院眼科门诊及住院病人,凡是眼底、荧光素眼底血管造影(FFA)或光学相干断层扫描仪(OCT)表现为水肿、出血及渗出的病人,均进行五脏相关的问卷调查,整个过程均无医师在旁行暗示性引导。病例收集完毕后,运用Stata统计软件,计算眼底改变与五脏的相关性,最后得出结论。进行前瞻性研究前,均向参与临床观察的病人,解释本研究的相关情况,同时取得病人的同意后方进行。
     结果:采用Stata统计软件分析发现,回顾性研究:共收集165例住院病人,其中眼底水肿者77例106眼,与肝、肾和脾相关;眼底出血者79例106眼,与肝、肾和脾相关;眼底渗出者90例128眼,与肝、脾相关;其中全部眼底表现均伴随瘀的存在。前瞻性研究:共收集37例住院及门诊病人,其中眼底水肿者26例35眼,与肝、肾和脾相关;眼底出血者29例41眼,与肝、肾和脾相关;眼底渗出者17例25眼,与肝、肾和脾相关;其中全部眼底表现均伴随瘀的存在。
     结论:通过对回顾性研究及前瞻性研究结果的综合分析,可得出以下结论:1.眼底表现为水肿的与肝、肾和脾相关;2.眼底表现为出血的与肝、肾和脾相关;3.眼底表现为渗出的与肝和脾相关;4.全部眼底表现均伴随瘀的存在。
Objetive:Discuss the Relation between the five internal organs and the classic syndrome of fundus changes of the Supernatural pupil,to reveal the feature of fundus changes of the Supernatural pupil
     Methods:The major study patients were from both parties:一.retrospective study:the inpatient were hospitalized in the First Affiliated Hospital of the Guangzhou University of TCM from January 2005 to December 2009, fundus changes manifest edema、hemorrhage and exudate, through the treatmemt of TCM and the tcm prescriptions to define the Relation between the five internal organs;二. prospective study:the inpatient and outpatient were hospitalized in the First Affiliated Hospital of the Guangzhou University of TCM from January 2010 to April 2011, all the fundus changes、FFA or OCT manifest edema、hemorrhage and exudate, were underway the questionnaire survey of correlation among five viscera, doctor give no hint in the process. After collect all the case, apply the statistical software of Stata, calculate the relation between the five internal organs and the fundus changes of the Supernatural pupil and draw the conclusion. Before the prospective study, all the patients in the study were explained the work-related condition of the study, and agreed.
     Results:Arrival at a conclusion after apply the statistical software of Stata,一.retrospective study:all the cases of the study were 165, the edema of fundus changes which count 77cases and 106 eyes is relate to liver、kidneys and spleen; the hemorrhage of fundus changes which count 79 cases and 106 eyes is relate to liver、kidneys and spleen; the exudate of fundus changes which count 90 cases and 128 eyes is relate to liver and spleen;all the fundus changes accompany stagnation二Prospective study:all the cases of the study were 37, the edema of fundus changes which count 26 cases and 35 eyes is relate to liver、kidneys and spleen; the hemorrhage of fundus changes which count 29 cases and 41 eyes is relate to liver、kidneys and spleen; the exudate of fundus changes which count 17 cases and 25 eyes is relate to liver、kidneys and spleen; all the fundus changes accompany stagnation.
     Conclusion:Arrival at a conclusion according to comprehensive analysis of the result of retrospective study and prospective study:1. The edema of fundus changes is relate to liver、kidneys and spleen; 2.The hemorrhage of fundus changes is relate to liver、kidneys and spleen; 3. The exudate of fundus changes is relate to liver and spleen;4. All the fundus changes accompany stagnation.
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