氟比洛芬酯用于全麻输尿管软镜碎石患者超前镇痛的观察
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- 论文作者：钱美娟 ; 崔晓丽
- 年：2016
- 作者机构：如皋市第一人民医院麻醉科;
- 论文关键词：全麻 ; 氟比洛芬酯 ; 输尿管软镜
- 英文论文关键词：general anesthesia ; flurbiprofen axetil ; flexible ureteroscope
- 会议召开时间：2016-11-25
- 会议录名称：湖南中医药大学学报2016/专集：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会论文集
- 语种：中文
- 分类号：R614
- 学会代码：HNZY
- 会议名称：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会
- 会议地点：中国广东珠海
- 主办单位：国际数字医学会、Digital Chinese Medicine
- 学会名称：湖南中医药大学期刊杂志社
- 页数：2
- 文件大小：1866k
- 原文格式：D
- 会议级别：全国
摘要
目的:探讨氟比洛芬酯在全麻输尿管软镜碎石术中患者超前镇痛的临床应用价值。方法:将2014年1月至2016年8月150例肾结石拟行输尿管软镜碎石的泌尿外科患者随机分为氟比洛芬酯(实验组)和对照组,每组各75例患者。实验组患者于术前30min开始使用氟比洛芬酯,对照组则予以注射脂肪乳,通过VAS评分法比较术后两组24h内(1h、3h、6h、12h、24h)的差异,并记录术后24h内使用曲马多的用量及不良反应情况。结果:实验组24h曲马多用量与对照组组比较有显著性差异(p<0.05);实验组术后1h、3h、6h、12h、24h患者VAS评分明显低于对照组(p<0.05);实验组与对照组在不良反应发生率的比较中无显著性差异(p>0.05)。结论:泌尿外科肾结石患者采用全麻下输尿管软镜碎石术中使用氟比洛芬酯进行超前镇痛,能明显较少术后镇痛药物使用量,临床效果佳,安全可靠。
objective To invest the clinical safety and efficacy of preemptive analgesia with flurbiprofen axetil on flexible ureteroscope. Methods In January 2014 to August 2016, 150 cases of kidney stones patients were randomly divided into flexible ureteroscope(experimental group) and control group, each group of 75 patients. Experimental group in patients with preoperative 30 min started using flurbiprofen axetil, fat emulsion injection control group, by the VAS score approach to compare two groups of postoperative within 24h(1h, 3h, 6h, 12 h, 24h), and records within 24 h after using the dosage of tramadol and adverse reactions. Results 24 h dosage of tramadol group compared with the control way has significant difference(p < 0.05); Experimental group after1 h, 3h, 6h, 12 h, 24 h patients VAS score significantly lower than the control group(p < 0.05); The comparision of the experimental group and control group in the incidence of adverse reactions therewas no significant difference(p > 0.05).Conclusion Urology kidney stones in patients using flexible ureteroscope under general anesthesia can significantly fewer postoperative analgesia drugusage, good clinical effect, safety and reliability.
objective To invest the clinical safety and efficacy of preemptive analgesia with flurbiprofen axetil on flexible ureteroscope. Methods In January 2014 to August 2016, 150 cases of kidney stones patients were randomly divided into flexible ureteroscope(experimental group) and control group, each group of 75 patients. Experimental group in patients with preoperative 30 min started using flurbiprofen axetil, fat emulsion injection control group, by the VAS score approach to compare two groups of postoperative within 24h(1h, 3h, 6h, 12 h, 24h), and records within 24 h after using the dosage of tramadol and adverse reactions. Results 24 h dosage of tramadol group compared with the control way has significant difference(p < 0.05); Experimental group after1 h, 3h, 6h, 12 h, 24 h patients VAS score significantly lower than the control group(p < 0.05); The comparision of the experimental group and control group in the incidence of adverse reactions therewas no significant difference(p > 0.05).Conclusion Urology kidney stones in patients using flexible ureteroscope under general anesthesia can significantly fewer postoperative analgesia drugusage, good clinical effect, safety and reliability.
引文
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[9]Wen Y,Wang M,Yang J,et al.A Comparison of Fentanyl and Flurbiprofen Axetil on Serum VEGF-C,TNF-α,and IL-1?Concentrations in Women Undergoing Surgery for Breast Cancer.Pain Pract.2015,15(6):530-537.
[2]Chai XQ,Ma J,Xie YH,et al.Flurbiprofen axetil increases arterial oxygen partial pressure by decreasing intrapulmonary shunt in patients undergoing one-lung ventilation.J Anesth.2015,29(6):881-886.
[3]Lin X,Zhang R,Xing J,et al.Flurbiprofen axetil reduces postoperative sufentanil consumption and enhances postoperative analgesic effects in patients with colorectal cancer surgery.Int J Clin Exp Med.2014,7(12):4887-4896.
[4]Zhang L,Zhu J,Xu L,et al.Efficacy and safety of flurbiprofen axetil in the prevention of pain on propofol injection:a systematic review and meta-analysis.Med Sci Monit.2014,17(20):995-1002.
[5]Wang Y,Zhang HB,Xia B,et al.Preemptive analgesic effects of flurbiprofen axetil in patients undergoing radical resection of esophageal carcinoma via the left thoracic approach.Chin Med J(Engl).2012,125(4):579-582.
[6]Fujita Y,Hasegawa S,Kato Y,et al.Intravenous injection of low-dose flurbiprofen axetil for preventing post-ERCP pancreatitis in high-risk patients:An interim analysis of the trial.Endosc Int Open.2016,4(10):1078-1082.
[7]Jiang WW,Wang QH,Peng P,et al.Effects of flurbiprofen axetil on postoperative serum IL-2and IL-6 levels in patients with colorectal cancer.Genet Mol Res.2015,14(4):16469-16475.
[8]Yu Z,Wu W,Wu X,et al.Protective effects of dexmedetomidine combined with flurbiprofen axetil on remifentanil-induced hyperalgesia:A randomized controlled trial.Exp Ther Med.2016,12(4):2622-2628.
[9]Wen Y,Wang M,Yang J,et al.A Comparison of Fentanyl and Flurbiprofen Axetil on Serum VEGF-C,TNF-α,and IL-1?Concentrations in Women Undergoing Surgery for Breast Cancer.Pain Pract.2015,15(6):530-537.