63例急性脊髓炎临床特征与激素治疗疗效分析
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- 论文作者：王彪 ; 阎登富 ; 马碧 ; 刘爱东
- 年：2016
- 作者机构：成都医学院第一附属医院;
- 论文关键词：急性脊髓炎 ; 激素 ; 甲基强的松龙
- 英文论文关键词：acute myelitis ; hormone ; Methylprednisolone
- 会议召开时间：2016年6月
- 会议录名称：2016《中国组织化学与细胞化学》杂志临床研究研讨会论文汇编
- 语种：中文
- 分类号：R744.3
- 学会代码：ZHXB
- 会议名称：2016《中国组织化学与细胞化学》杂志临床研究研讨会
- 会议地点：中国北京
- 主办单位：《中国组织化学与细胞化学杂志》社有限公司
- 学会名称：《中国组织化学与细胞化学杂志》社有限公司
- 页数：2
- 文件大小：257k
- 原文格式：O
- 会议级别：全国
摘要
目的:研究急性脊髓炎的临床特征,并分析激素治疗的效果。方法:选取我院在2012年2月~2015年10月收治的63例急性脊髓炎患者作为研究对象,对所有患者的临床资料进行回顾性分析,总结急性脊髓炎的临床特征。同时将所有患者以随机分方式划分为观察组和对照组,观察组33例,对照组30例,观察组配合甲强龙(甲基强的松龙)进行治疗,对照组配合地塞米松进行治疗,观察并比较两组患者的治疗效果。结果:急性脊髓炎的主要临床特征为感觉障碍、双下肢截瘫、四肢瘫、括约肌功能障碍和神经影像学异常等。分析并研究组的治疗情况,观察组的治疗有效率高于对照组,P<0.05,差异明显,具有统计学意义;治疗后3个月,对两组患者的神经功能恢复情况等进行比较,观察组优于对照组,P<0.05,差异明显,具有统计学意义。结论:急性脊髓炎的临床表现较为严重,可谓患者造成严重的生活影响,为患者配合激素甲强龙进行治疗,效果更好,可提高治疗有效率,促进患者的恢复,值得在临床上推广使用。
Objective:To study the clinical features of acute myelitis,and analyze the effect of hormone therapy.Methods:in our hospital in February2012 ~ 2015 year in October treated 63 cases of acute myelitis patients as the research object,the clinical data of all patients were retrospectively analyzed to summarize the clinical features of acute myelitis.At the same time,all patients were randomly divided into the observation group and control group,33 cases in the observation group,30 cases in the control group,the observation group with methylprednisolone(MP) treatment,the control group were treated with dexamethasone,the treatment effect of two groups were observed and compared.Results:the main clinical features of acute myelitis as sensory disturbance,paraplegia,tetraplegia,sphincter dysfunction and neuroimaging abnormalities.Analysis and treatment of the study group,the effective rate in the treatment group than the control group,P < 0.05,significant difference was statistically significant:3 months after treatment,the two groups of patients with neurological functional recovery were compared,the observation group than the control group,P < 0.05,difference was statistically significant.Conclusion:the clinical manifestation of acute myelitis is more serious,causing serious impact on life can be described as patients,treatment for patients with hormone methylprednisolone has better effect,can improve the treatment efficiency,and promote the recovery of patients,it is worth popularizing in clinical use.
Objective:To study the clinical features of acute myelitis,and analyze the effect of hormone therapy.Methods:in our hospital in February2012 ~ 2015 year in October treated 63 cases of acute myelitis patients as the research object,the clinical data of all patients were retrospectively analyzed to summarize the clinical features of acute myelitis.At the same time,all patients were randomly divided into the observation group and control group,33 cases in the observation group,30 cases in the control group,the observation group with methylprednisolone(MP) treatment,the control group were treated with dexamethasone,the treatment effect of two groups were observed and compared.Results:the main clinical features of acute myelitis as sensory disturbance,paraplegia,tetraplegia,sphincter dysfunction and neuroimaging abnormalities.Analysis and treatment of the study group,the effective rate in the treatment group than the control group,P < 0.05,significant difference was statistically significant:3 months after treatment,the two groups of patients with neurological functional recovery were compared,the observation group than the control group,P < 0.05,difference was statistically significant.Conclusion:the clinical manifestation of acute myelitis is more serious,causing serious impact on life can be described as patients,treatment for patients with hormone methylprednisolone has better effect,can improve the treatment efficiency,and promote the recovery of patients,it is worth popularizing in clinical use.
引文
[1]高艳.急性脊髓炎的临床特征以及激素治疗效果[J].中国医药指南,2015,22(36):253-254.
[2]冷函.甲泼尼龙冲击疗法辅治急性脊髓炎的临床效果分析[J].中国医药指南,2014,04(31):1634-1636.
[2]冷函.甲泼尼龙冲击疗法辅治急性脊髓炎的临床效果分析[J].中国医药指南,2014,04(31):1634-1636.