卵巢成熟性囊性畸胎瘤恶变临床病理分析
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- 论文作者：姚锡虎 ; 周建英 ; 张志成
- 年：2016
- 作者机构：福建省泉州市第一医院病理科;福建省泉州市第一医院麻醉科;福建省泉州市第一医院放射科;
- 论文关键词：卵巢成熟性畸胎瘤 ; 恶变 ; 临床病理情况
- 英文论文关键词：mature teratoma ; malignant transformation ; clinical pathology
- 会议召开时间：2016年6月
- 会议录名称：2016《中国组织化学与细胞化学》杂志临床研究研讨会论文汇编
- 语种：中文
- 分类号：R737.31
- 学会代码：ZHXB
- 会议名称：2016《中国组织化学与细胞化学》杂志临床研究研讨会
- 会议地点：中国北京
- 主办单位：《中国组织化学与细胞化学杂志》社有限公司
- 学会名称：《中国组织化学与细胞化学杂志》社有限公司
- 页数：1
- 文件大小：137k
- 原文格式：O
- 会议级别：全国
摘要
目的:探究卵巢成熟性畸胎瘤恶变临床病理情况。方法:对我院2005年1月到2015年12月接收的12例卵巢成熟性畸胎瘤恶变病例进行回顾性分析,探究病理学基本情况。结果:患者的临床表现为不同程度的腹痛、纳差及下腹部包块等;患者肿瘤位置在双两侧卵巢占8.33%,在右侧占33.33%,在左侧占58.33%;手术方式均为双侧附件切除和全子宫切除。12例中有1例患者同时进行盆腔淋巴结清扫术、有1例同时进行部分直肠切除,有2例同时进行了阑尾切除;对肿瘤进行检查可见肿瘤均为囊性或囊实性,实性区边界较为模糊、切面颜色以灰色为主、同时泛白、泛黄;12例患者中鳞状细胞癌占75.00%,类癌占16.67%,有1例患者为低分化腺癌占8.33%。结论:卵巢成熟性畸胎瘤恶变对于患者影响较大,因此我们应该及时对患者进行全面的病理检查和分析,便于作出准确的病理诊断,指导临床治疗,改善患者预后及提高患者生存质量。
Objective:To explore the malignant transformation of ovarian mature teratoma clinical pathology.Methods:12 cases of ovarian mature teratoma with malignant transformation in our hospital in January 2005 to December 2015 were retrospectively analyzed received explore the basic pathological conditions.Results:The clinical manifestations of patients with different degrees of abdominal pain,anorexia and lower abdominal mass and so on:the position of the tumor in patients with both ovaries accounted for 8.33%,on the right side(33.33%),accounting for 58.33%in the left:surgical methods are bilateral oophorectomy and hysterectomy.12 cases,1 patient simultaneous pelvic lymph node dissection,there is one case of simultaneous partial resection of the rectum,there are two cases simultaneously appendectomy:examination of tumors visible tumors were cystic or solid,solid areas more fuzzy boundaries,cut mainly gray color,while white,yellowing:12 patients with squamous cell carcinoma accounts for 75.00%,accounting for 16.67%of carcinoid tumors,one patient poorly differentiated adenocarcinoma accounted for 8.33%.Conclusion:the malignant transformation of ovarian mature teratoma have a greater impact,so we should be timely and comprehensive patient pathological examination and analysis,easy to make an accurate pathological diagnosis,clinical treatment,improved patient outcomes and improve the quality of life of patients.
Objective:To explore the malignant transformation of ovarian mature teratoma clinical pathology.Methods:12 cases of ovarian mature teratoma with malignant transformation in our hospital in January 2005 to December 2015 were retrospectively analyzed received explore the basic pathological conditions.Results:The clinical manifestations of patients with different degrees of abdominal pain,anorexia and lower abdominal mass and so on:the position of the tumor in patients with both ovaries accounted for 8.33%,on the right side(33.33%),accounting for 58.33%in the left:surgical methods are bilateral oophorectomy and hysterectomy.12 cases,1 patient simultaneous pelvic lymph node dissection,there is one case of simultaneous partial resection of the rectum,there are two cases simultaneously appendectomy:examination of tumors visible tumors were cystic or solid,solid areas more fuzzy boundaries,cut mainly gray color,while white,yellowing:12 patients with squamous cell carcinoma accounts for 75.00%,accounting for 16.67%of carcinoid tumors,one patient poorly differentiated adenocarcinoma accounted for 8.33%.Conclusion:the malignant transformation of ovarian mature teratoma have a greater impact,so we should be timely and comprehensive patient pathological examination and analysis,easy to make an accurate pathological diagnosis,clinical treatment,improved patient outcomes and improve the quality of life of patients.
引文
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[5]沈丹华,张雅贤,薛为成,等.卵巢成熟性囊性畸胎瘤恶变临床病理分析及人类乳头状瘤病毒检测[J].北京医科大学学报,1999,31(4):331—334.
[6]刘磊玉,周赤,荪波.卵巢成熟性囊性畸胎瘤合并黏液性交界性肿瘤临床病理观察[J].诊断病理学杂志,2013,20(7):419—424.
[7]Mori Y,Nishii H,Takabe K,et al.Preoperative diagnosis of malignant transformation arising from mature cystic teratoma of the ovary[J].Gynecol Oncol,2003,90(2):338-41.
[8]Stephen C。Rubin D。Gregory P。et al.Ovarian cancer[M].New York;Mc Graw-Hill 1993;141-143.
[2]李宁.卵巢成熟性畸胎瘤恶变成鳞形细胞癌的临床病理分析[J].河北医学,2013,19(10):1520—1523.
[3]闰风彩,陈奕至,周全,等.卵巢成熟性囊性畸胎瘤合并类癌2例临床病理观察[J].诊断病理学杂志,2015,22(12):761—764.
[4]Nassar H,Pansare V,Zhang H,Che M,et al.Pathogenesis of invasive micropapillary carcinoma:role of MUC1 glycoprotein.Mod Pathol 2004,17:1045-1050.
[5]沈丹华,张雅贤,薛为成,等.卵巢成熟性囊性畸胎瘤恶变临床病理分析及人类乳头状瘤病毒检测[J].北京医科大学学报,1999,31(4):331—334.
[6]刘磊玉,周赤,荪波.卵巢成熟性囊性畸胎瘤合并黏液性交界性肿瘤临床病理观察[J].诊断病理学杂志,2013,20(7):419—424.
[7]Mori Y,Nishii H,Takabe K,et al.Preoperative diagnosis of malignant transformation arising from mature cystic teratoma of the ovary[J].Gynecol Oncol,2003,90(2):338-41.
[8]Stephen C。Rubin D。Gregory P。et al.Ovarian cancer[M].New York;Mc Graw-Hill 1993;141-143.
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