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需氧菌与假丝酵母菌感染对胎膜早破母婴不良结局的影响
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摘要
目的:探讨需氧菌与假丝酵母菌感染对胎膜早破母婴不良结局的影响,从而为预防胎膜早破的发生而改善母婴结局提供科学的理论依据。方法:以我院妇产科在2011年12月-2012年12月收治的300例由于胎膜早破而对生殖道分泌物进行细菌培养检测的患者作为研究对象,进一步对该组人群中需氧菌感染和假丝酵母菌感染患者所发生母婴不良结局,如早产、生产方式、新生儿窒息、胎儿产前感染以及新生儿死亡等方面进行组间分析。结果:通过对300例胎膜早破患者生殖道分泌物进行细菌培养检测,其结果发现需氧菌感染患者与假丝酵母菌感染患者所占该人群百分比23.67%和25.00%,其中需氧菌主要为B型溶血性链球菌和大肠埃希菌,而假丝酵母菌主要为白假丝酵母菌和光滑拟球酵母菌。进一步比较发现需氧菌感染组胎膜早破患者产前感染、胎儿窘迫、围生儿死亡等母婴不良结局发生率明显高于假丝酵母菌感染组。通过统计学方法进行检验分析,上述两组间的差异具有统计学意义(P<0.05)。结论:需氧菌与假丝酵母菌感染与胎膜早破母婴不良结局间存在密切关系,因此,应加强对孕期生殖道病原微生物的检查,并积极使用抗菌药物进行有效治疗,从而减少胎膜早破母婴不良结局的发生。
Objective: To investigate the aerobic bacteria and Candida infection effect on premature rupture of membranes adverse pregnancy outcomes, so as to prevent the premature rupture ofmembranes and improve maternal and child outcome provides scientific theoretical basis. Methods: in our hospital 300 cases of Obstetrics and gynecology in 2011 December-2012 year in Decemberadmitted because of bacterial culture detection of patients as the research object on the reproductive tract secretions of premature rupture of membranes, and further to the aerobic bacteria infection andCandida yeast infection patients in the group what happened to poor pregnancy outcomes such as preterm delivery, analysis, mode of production, neonatal asphyxia, fetal prenatal infection and neonataldeaths and other aspects of group. Results: bacterial culture detection based on 300 cases of premature rupture of membranes in patients with genital tract secretions, the outcoming showed that patientswith Candida infection patients accounted for 23.67% and 25% of the population percentage infection of aerobic bacteria, including aerobic bacteria mainly B type hemolytic streptococci and Escherichiacoli, and Candida albicans were mainly Candida albicans and yeast to smooth ball. Further comparison showed that the aerobic bacteria infection group in patients with premature rupture of membranesprenatal infection, fetal distress, perinatal death maternal adverse outcome was significantly higher than the incidence of Candida albicans infection group. Analyzed by statistical approachs, statisticalsignificance of the differences among the two groups(P < 0.05). Conclusion: there is a close relationship between poor pregnancy outcomes of aerobic bacteria and Candida infection and prematurerupture of membranes, therefore, should strengthen the maternal reproductive tract pathogenic microorganism inspection, and actively use of antimicrobial drugs are effective in the treatment of prematurerupture of membranes, thereby reducing the occurrence of adverse pregnancy outcomes.
引文
[1]杨娜,刘敬,黄俊,等.胎膜早破致新生儿感染的病原学分析[J].中华全科医师杂志,2012,11(3):199-201.
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    [4]夏淑琦,李仁良,林胜兰,等.胎膜早破生殖道感染检测与不良妊娠结局分析[J].中国卫生检验杂志,2011,21(5):45-46.
    [5]杨秀丽,杨慧霞,段涛,等.产后妇女阴道菌群状况及其影响因素分析[J].中华妇产科杂志,2013,44(7):496-499.

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