脑钠肽对合并高血压病的急性冠脉综合征介入治疗预后价值的相关分析
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- 论文作者：贺文奇 ; 楚英杰
- 年：2016
- 作者机构：河南省人民医院急诊内科;
- 论文关键词：脑钠肽 ; 急性冠脉综合征 ; 高血压 ; 介入治疗
- 英文论文关键词：brain natriuretic peptide ; Acute coronary syndrome ; High blood pressure ; Interventional therapy
- 会议召开时间：2016-11-25
- 会议录名称：湖南中医药大学学报2016/专集：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会论文集
- 语种：中文
- 分类号：R541.4;R544.1
- 学会代码：HNZY
- 会议名称：国际数字医学会数字中医药分会成立大会暨首届数字中医药学术交流会
- 会议地点：中国广东珠海
- 主办单位：国际数字医学会、Digital Chinese Medicine
- 学会名称：湖南中医药大学期刊杂志社
- 页数：1
- 文件大小：1886k
- 原文格式：D
- 会议级别：全国
摘要
目的:探讨脑钠肽对于急性冠脉综合征合并高血压患者介入治疗后的预后价值。方法:选取我院急性冠脉综合征合并高血压患者54例作为研究对象,患者均经过经皮冠状动脉介入治疗,在手术48小时之后,采集患者静脉血,测量血液中BNP的浓度,以BNP 100pg/ml作为临界值,将患者分为两组,分别为A组和B组,A组患者血清BNP≥100pg/ml,B组患者血清BNP<100pg/ml,其中A组25人,B组29人,两组患者分别观察经过治疗之后6个月内心血管事件发生的情况,包括患者死亡、心绞痛、再次发生心梗、心源性休克及心力衰竭等。结果:PCI治疗之后6个月之内,两组患者心血管事件的发生情况为:A组死亡1人,心绞痛12人,心源性休克2人,非致命心衰5人,其它2例;B组患者心绞痛4人,非致命性心衰1人,其它1例,A组患者术后心血管疾病发生率显著高于B组患者,经统计学处理存在显著性差异(P<0.05),具有统计学意义。结论:急性冠脉综合征合并高血压患者介入治疗后血液BNP浓度对于心血管疾病的发生有较好的预测作用。
objective To investigate the brain natriuretic peptide in patients with acute coronary syndrome of hypertension after interventional therapy of prognostic value. Methods 54 patients with acute coronary syndrome of hypertension patients as the research object, the patients after percutaneous coronary intervention, 48 hours after the surgery, patients with venous bloodcollected, measurement of BNP concentrations in the blood, the BNP 100 pg/ml as A critical value, divided the patients into two groups: group A and group B respectively, A group of patients serumBNP acuity 100 pg/ml, group B patients serum BNP < 100 pg/ml, including 25 in group A, group B 29 people, two groups of patients were observed within 6 months after treatment for cardiovascularevents, including death, angina pectoris, recurrence of myocardial infarction, cardiac shock and heart failure, etc. Results PCI within 6 months after treatment, the occurrence of cardiovascularevents in patients with two groups: group A 1 death, angina pectoris 12 people, cardiac shock, 2 people, 5 non-fatal heart failure, the other 2 cases; B group of patients with angina pectoris fourpeople, 1 non-fatal heart failure, other 1 case, A group had A significantly higher incidence of postoperative cardiovascular disease in patients with B group of patients, after statistics processingexists significant difference(P < 0.05), with statistical significance. Conclusion Acute coronary syndrome after interventional therapy of hypertension patients blood BNP concentration for theoccurrence of cardiovascular disease has good prediction effect.
objective To investigate the brain natriuretic peptide in patients with acute coronary syndrome of hypertension after interventional therapy of prognostic value. Methods 54 patients with acute coronary syndrome of hypertension patients as the research object, the patients after percutaneous coronary intervention, 48 hours after the surgery, patients with venous bloodcollected, measurement of BNP concentrations in the blood, the BNP 100 pg/ml as A critical value, divided the patients into two groups: group A and group B respectively, A group of patients serumBNP acuity 100 pg/ml, group B patients serum BNP < 100 pg/ml, including 25 in group A, group B 29 people, two groups of patients were observed within 6 months after treatment for cardiovascularevents, including death, angina pectoris, recurrence of myocardial infarction, cardiac shock and heart failure, etc. Results PCI within 6 months after treatment, the occurrence of cardiovascularevents in patients with two groups: group A 1 death, angina pectoris 12 people, cardiac shock, 2 people, 5 non-fatal heart failure, the other 2 cases; B group of patients with angina pectoris fourpeople, 1 non-fatal heart failure, other 1 case, A group had A significantly higher incidence of postoperative cardiovascular disease in patients with B group of patients, after statistics processingexists significant difference(P < 0.05), with statistical significance. Conclusion Acute coronary syndrome after interventional therapy of hypertension patients blood BNP concentration for theoccurrence of cardiovascular disease has good prediction effect.
引文
[1]游向东,邸龙辉,侯冰洁等.急性冠脉综合征合并高血压患者PCI术后血浆脑钠肽对心功能评价的研究[J].实用心脑肺血管病杂志,2012,20(11):1810-1811.
[2]刘军,赵冬,刘群等.中国多中心急性冠脉综合征患者高血压控制现况[J].中华高血压杂志,2008,16(1):16-20.
[3]金鑫,陈安芳,唐成玥等.H型高血压对非ST段抬高急性冠脉综合征GRACE评分和N-末端脑钠肽的影响[J].四川医学,2015,(7):1005-1007.
[4]王澈,齐大屯.介入治疗对急性冠脉综合征患者血小板活化及炎症因子的影响[J].中国老年学杂志,2012,32(22):5022-5023.
[5]周耀辉.急性冠脉综合征介入治疗后脑钠肽水平与预后关系[J].中国中医药现代远程教育,2012,10(16):36-37.
[6]黄玉娜,王玉丰.急性冠状动脉综合征患者介入治疗前后NT-pro BNP水平的变化[J].国际检验医学杂志,2013,34(8):1038-1039.
[7]全楚杰,翟永新,白建雄等.介入治疗对非ST段抬高型急性冠脉综合征患者心功能的影响[J].罕少疾病杂志,2016,23(3):4-6.
[2]刘军,赵冬,刘群等.中国多中心急性冠脉综合征患者高血压控制现况[J].中华高血压杂志,2008,16(1):16-20.
[3]金鑫,陈安芳,唐成玥等.H型高血压对非ST段抬高急性冠脉综合征GRACE评分和N-末端脑钠肽的影响[J].四川医学,2015,(7):1005-1007.
[4]王澈,齐大屯.介入治疗对急性冠脉综合征患者血小板活化及炎症因子的影响[J].中国老年学杂志,2012,32(22):5022-5023.
[5]周耀辉.急性冠脉综合征介入治疗后脑钠肽水平与预后关系[J].中国中医药现代远程教育,2012,10(16):36-37.
[6]黄玉娜,王玉丰.急性冠状动脉综合征患者介入治疗前后NT-pro BNP水平的变化[J].国际检验医学杂志,2013,34(8):1038-1039.
[7]全楚杰,翟永新,白建雄等.介入治疗对非ST段抬高型急性冠脉综合征患者心功能的影响[J].罕少疾病杂志,2016,23(3):4-6.