Cell signaling associated with internalization of 67 kDa laminin receptor (67LR) by soluble laminin and its implication for protection against neurodegenerative diseases
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摘要
<正>Various isoforms of laminins are present in the basement membranes complexed with other structural proteins. In the central nervous system(CNS), they are primarily localized to the basement membranes of blood vessels and reactive astrocytes. Limited amounts of various laminin isoforms are also associated with neuronal cell bodies and axons, which are referred to as "neuronal" laminins(Yamamoto et al., 1988). They exist in a soluble form, free
引文
Da Costa Dias B,Jovanovic K,Gonsalves D,Moodley K,Reusch U,Knackmuss S,Weinberg MS,Little M,Weiss SF(2014)The 37kDa/67kDa laminin receptor acts as a receptor for Abeta42 internalization.Sci Rep 4:5556.
Drouet B,Pincon-Raymond M,Chambaz J,Pillot T(1999)Laminin 1 attenuates beta-amyloid peptide Abeta(1-40)neurotoxicity of cultured fetal rat cortical neurons.J Neurochem 73:742-749.
Gopalakrishna R,Gundimeda U,Zhou S,Bui H,Davis A,McNeill T,Mack W(2018)Laminin-1 induces endocytosis of 67KDa laminin receptor and protects Neuroscreen-1 cells against death induced by serum withdrawal.Biochem Biophys Res Commun 495:230-237.
Gundimeda U,McNeill TH,Fan TK,Deng R,Rayudu D,Chen Z,Cadenas E,Gopalakrishna R(2014)Green tea catechins potentiate the neuritogenic action of brain-derived neurotrophic factor:role of 67-kDa laminin receptor and hydrogen peroxide.Biochem Biophys Res Commun 445:218-224.
Jarosz-Griffiths HH,Noble E,Rushworth JV,Hooper NM(2016)Amyloid-beta receptors:the good,the bad,and the prion Protein.J Biol Chem 291:3174-3183.
Lee B,Clarke D,Al Ahmad A,Kahle M,Parham C,Auckland L,Shaw C,Fidanboylu M,Orr AW,Ogunshola O,Fertala A,Thomas SA,Bix GJ(2011)Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents.J Clin Invest 121:3005-3023.
Nelson J,McFerran NV,Pivato G,Chambers E,Doherty C,Steele D,Timson DJ(2008)The 67 kDa laminin receptor:structure,function and role in disease.Biosci Rep 28:33-48.
Sorkin A,von Zastrow M(2009)Endocytosis and signalling:intertwining molecular networks.Nat Rev Mol Cell Biol 10:609-622.
Tachibana H,Koga K,Fujimura Y,Yamada K(2004)A receptor for green tea polyphenol EGCG.Nat Struct Mol Biol 11:380-381.
Vilardaga JP,Jean-Alphonse FG,Gardella TJ(2014)Endosomal generation of cAMP in GPCR signaling.Nat Chem Biol 10:700-706.
Weinreb O,Mandel S,Amit T,Youdim MBH(2004)Neurological mechanisms of green tea polyphenols in Alzheimer’s and Parkinson’s diseases.J Nutr Biochem 15:506-516.
Yamamoto T,Iwasaki Y,Yamamoto H,Konno H,Isemura M(1988)Intraneuronal laminin-like molecule in the central nervous system:demonstration of its unique differential distribution.J Neurol Sci 84:1-13.
Drouet B,Pincon-Raymond M,Chambaz J,Pillot T(1999)Laminin 1 attenuates beta-amyloid peptide Abeta(1-40)neurotoxicity of cultured fetal rat cortical neurons.J Neurochem 73:742-749.
Gopalakrishna R,Gundimeda U,Zhou S,Bui H,Davis A,McNeill T,Mack W(2018)Laminin-1 induces endocytosis of 67KDa laminin receptor and protects Neuroscreen-1 cells against death induced by serum withdrawal.Biochem Biophys Res Commun 495:230-237.
Gundimeda U,McNeill TH,Fan TK,Deng R,Rayudu D,Chen Z,Cadenas E,Gopalakrishna R(2014)Green tea catechins potentiate the neuritogenic action of brain-derived neurotrophic factor:role of 67-kDa laminin receptor and hydrogen peroxide.Biochem Biophys Res Commun 445:218-224.
Jarosz-Griffiths HH,Noble E,Rushworth JV,Hooper NM(2016)Amyloid-beta receptors:the good,the bad,and the prion Protein.J Biol Chem 291:3174-3183.
Lee B,Clarke D,Al Ahmad A,Kahle M,Parham C,Auckland L,Shaw C,Fidanboylu M,Orr AW,Ogunshola O,Fertala A,Thomas SA,Bix GJ(2011)Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents.J Clin Invest 121:3005-3023.
Nelson J,McFerran NV,Pivato G,Chambers E,Doherty C,Steele D,Timson DJ(2008)The 67 kDa laminin receptor:structure,function and role in disease.Biosci Rep 28:33-48.
Sorkin A,von Zastrow M(2009)Endocytosis and signalling:intertwining molecular networks.Nat Rev Mol Cell Biol 10:609-622.
Tachibana H,Koga K,Fujimura Y,Yamada K(2004)A receptor for green tea polyphenol EGCG.Nat Struct Mol Biol 11:380-381.
Vilardaga JP,Jean-Alphonse FG,Gardella TJ(2014)Endosomal generation of cAMP in GPCR signaling.Nat Chem Biol 10:700-706.
Weinreb O,Mandel S,Amit T,Youdim MBH(2004)Neurological mechanisms of green tea polyphenols in Alzheimer’s and Parkinson’s diseases.J Nutr Biochem 15:506-516.
Yamamoto T,Iwasaki Y,Yamamoto H,Konno H,Isemura M(1988)Intraneuronal laminin-like molecule in the central nervous system:demonstration of its unique differential distribution.J Neurol Sci 84:1-13.