微波热声成像技术用于人体甲状腺检测

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英文篇名：Microwave-induced Thermoacoustic Tomography for Imaging Human Thyroid 作者：王雪 ; 黄林 ; 迟子惠 ; 蒋华北 英文作者：WANG Xue;HUANG Lin;CHI Zi-Hui;JIANG Hua-Bei;School of Electronic Science and Engineering, University of Electronic Science and Technology of China;Center for Information in Medicine, University of Electronic Science and Technology of China;Department of Medical Engineering, University of South Florida; 关键词：微波热声成像 ; 图像重建 ; 甲状腺 ; 诊断 英文关键词：thermoacoustic imaging;;image reconstruction;;thyroid;;diagnosis 中文刊名：SHSW 英文刊名：Progress in Biochemistry and Biophysics 机构：电子科技大学电子科学与工程学院;电子科技大学医学信息研究中心;Department of Medical Engineering University of South Florida; 出版日期：2019-01-20 出版单位：生物化学与生物物理进展 年：2019 期：v.46 基金：国家自然科学基金(61701076)资助项目~~ 语种：中文; 页：SHSW201901008 页数：8 CN：01 ISSN：11-2161/Q 分类号：74-81

摘要

本文首次通过人体实验验证了微波热声成像技术用于人体甲状腺检测的可行性.文章首先讨论了该技术用于人体甲状腺检测的可行性;然后对3名志愿者的健康甲状腺进行了微波热声成像实验.结果表明:微波热声成像能够对人体健康甲状腺进行清晰成像,能够真实反映皮肤、甲状腺和气管等不同组织的结构特征;并且一次完整的检测过程时间约5 s,系统操作简单成像快速.综上所述,微波热声成像技术有望为甲状腺疾病的基础研究和临床诊断提供一种新的影像学参考.
        Microwave-induced thermoacoustic imaging(TAI) is an emerging new imaging technology. This article opens a new direction for this technology to image human thyroid. The thermoacoustic system used in this study consists of a pulse microwave source, flexible array detectors, a customized thyroid stent, multi-channel data acquisition devices and a data reconstruction system. We described the basic theory of microwave-induced thermoacoustic imaging and discussed theoretically the feasibility of this thermoacoustic system for human thyroid imaging. Thermoacoustic imaging experiments were performed on the healthy thyroid of three volunteers.The results showed that the system can clearly image the healthy thyroid gland and truly reflect the structural characteristics of different tissues including the skin, thyroid and trachea. A complete data collection process takes about 5 seconds, and therefore, the system operation is simple and fast. This study indicates that TAI may become a new imaging tool for basic research and clinical diagnosis of thyroid diseases.

引文

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