黄体功能不全型先兆流产患者使用黄体酮单药或联用地屈孕酮治疗的临床效果探究
|
摘要
目的探讨黄体功能不全型先兆流产患者使用黄体酮单药或联用地屈孕酮治疗的临床效果探究。方法选取2017年1月至2018年1月期间的黄体功能不全型先兆流产患者106名,按照数字表法,将53例设置为对照组,53例设置为研究组,控制两组用药,分析两组恢复情况和疗效。结果经研究实验后数据表明,研究组的患者治疗后总有效率为81.1%,对照组的患者治疗后总有效率为64.2%,研究组患者有效率高于对照组(P<0.05)。结论地屈孕酮与黄体酮联用在治疗黄体功能不全型先兆流产患者的应用效果理想,用于提高患者的恢复速度价值高,在临床上应当进一步推广应用。
Objective To explore the clinical effect of progesterone alone or combined with dextroprogesterone in the treatment of threatened abortion with luteal insufficiency. Methods 106 cases of threatened abortion with luteal insufficiency from January 2017 to January 2018 were selected. According to the digital table method, 53 cases were set as the control group and 53 cases as the study group. Results The data showed that the effective rate of the study group was higher than that of the control group(P<0.05). The total effective rate was 81.1% in the study group and64.2% in the control group. Conclusion The combination of DDR and progesterone is effective in the treatment of threatened abortion with luteal insufficiency. It has high value in improving the recovery rate of patients and should be further popularized in clinic.
Objective To explore the clinical effect of progesterone alone or combined with dextroprogesterone in the treatment of threatened abortion with luteal insufficiency. Methods 106 cases of threatened abortion with luteal insufficiency from January 2017 to January 2018 were selected. According to the digital table method, 53 cases were set as the control group and 53 cases as the study group. Results The data showed that the effective rate of the study group was higher than that of the control group(P<0.05). The total effective rate was 81.1% in the study group and64.2% in the control group. Conclusion The combination of DDR and progesterone is effective in the treatment of threatened abortion with luteal insufficiency. It has high value in improving the recovery rate of patients and should be further popularized in clinic.
引文
[1]张肇桂,杨淑华,郑萍萍.孕康颗粒联合地屈孕酮治疗早期先兆流产的临床观察[J].中国药房,2016,27(23):3229-3231.
[2]李慧,吴小妹,周玉华.低分子肝素钠联合地屈孕酮治疗先兆流产的临床观察[J].中国药房,2017,28(18):2499-2502.
[3]方芳,胡丽莎,陈晓勇,等.寿胎丸加减方联合地屈孕酮治疗早期先兆流产合并绒毛膜下血肿临床研究[J].时珍国医国药,2016,67(4):893-894.
[4]田春漫,陈波.固肾安胎丸联用黄体酮对先兆流产患者血清β-HCG,P,E2和CA125水平的影响[J].中国中药杂志,2016,41(2):321-325.
[5]陈阳,李丹阳,李晓鹏,等.寿胎丸对肾虚-黄体功能不全性流产大鼠Kisspeptin-10的影响[J].中药材,2017,40(2):452-456.
[6]孙莉,魏铭,梁葵香,等.寿胎四君子汤与黄体酮治疗早期先兆流产的临床效果分析[J].中药药理与临床,2016,90(2):222-224.
[7]薛薇,邓燕,王艳芳,等.低剂量与标准剂量结合雌激素联合天然孕酮或地屈孕酮治疗围绝经期综合征的疗效观察[J].实用妇产科杂志,2017,33(5):388-391.
[8]蔡志善,黄河.低剂量黄体酮注射液联合保胎无忧胶囊治疗先兆流产的疗效分析[J].中国药房,2017,28(6):759-761.
[9]叶章群,蓝儒竹,沈周俊,等.癃清片与左氧氟沙星单药或联合应用治疗非细菌性炎症性前列腺炎的临床研究[J].中华泌尿外科杂志,2016,37(5):363-367.
[10]崔克勤,王海燕,唐键,等.利拉鲁肽单药治疗新诊超重或肥胖2型糖尿病的效果及安全性观察[J].山东医药,2016,56(30):47-49.
[11]周伯如,戴佳轩,徐建亚,等.排卵后给予米非司酮对雌性大鼠动情周期、黄体功能的影响及意义[J].山东医药,2017,99(44):32-35.
[12]杜就旧,韩毓,赵海燕,等.盐酸利托君联合黄体酮对高龄二胎先兆流产患者血清HCG、孕酮水平及妊娠结局的影响[J].广东医学,2018,108(44):1002-1005.
[13]周媛萍,吴晓云,朱玉蓉,等.辅助生殖技术中阴道局部给药黄体支持方案中血清低孕酮水平的临床疗效研究[J].中华生殖与避孕杂志,2017,87(11):870-873.
[2]李慧,吴小妹,周玉华.低分子肝素钠联合地屈孕酮治疗先兆流产的临床观察[J].中国药房,2017,28(18):2499-2502.
[3]方芳,胡丽莎,陈晓勇,等.寿胎丸加减方联合地屈孕酮治疗早期先兆流产合并绒毛膜下血肿临床研究[J].时珍国医国药,2016,67(4):893-894.
[4]田春漫,陈波.固肾安胎丸联用黄体酮对先兆流产患者血清β-HCG,P,E2和CA125水平的影响[J].中国中药杂志,2016,41(2):321-325.
[5]陈阳,李丹阳,李晓鹏,等.寿胎丸对肾虚-黄体功能不全性流产大鼠Kisspeptin-10的影响[J].中药材,2017,40(2):452-456.
[6]孙莉,魏铭,梁葵香,等.寿胎四君子汤与黄体酮治疗早期先兆流产的临床效果分析[J].中药药理与临床,2016,90(2):222-224.
[7]薛薇,邓燕,王艳芳,等.低剂量与标准剂量结合雌激素联合天然孕酮或地屈孕酮治疗围绝经期综合征的疗效观察[J].实用妇产科杂志,2017,33(5):388-391.
[8]蔡志善,黄河.低剂量黄体酮注射液联合保胎无忧胶囊治疗先兆流产的疗效分析[J].中国药房,2017,28(6):759-761.
[9]叶章群,蓝儒竹,沈周俊,等.癃清片与左氧氟沙星单药或联合应用治疗非细菌性炎症性前列腺炎的临床研究[J].中华泌尿外科杂志,2016,37(5):363-367.
[10]崔克勤,王海燕,唐键,等.利拉鲁肽单药治疗新诊超重或肥胖2型糖尿病的效果及安全性观察[J].山东医药,2016,56(30):47-49.
[11]周伯如,戴佳轩,徐建亚,等.排卵后给予米非司酮对雌性大鼠动情周期、黄体功能的影响及意义[J].山东医药,2017,99(44):32-35.
[12]杜就旧,韩毓,赵海燕,等.盐酸利托君联合黄体酮对高龄二胎先兆流产患者血清HCG、孕酮水平及妊娠结局的影响[J].广东医学,2018,108(44):1002-1005.
[13]周媛萍,吴晓云,朱玉蓉,等.辅助生殖技术中阴道局部给药黄体支持方案中血清低孕酮水平的临床疗效研究[J].中华生殖与避孕杂志,2017,87(11):870-873.