不同功率微波辐射下牛晶状体非热效应定量研究
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摘要
为实现对生物体微波非热效应的定量表征,提出通过测量微波辐射过程中生物组织的介电系数变化来定量表征微波生物非热效应。将基于二端口微波对消电路原理,通过测量S_(21)参数以及晶状体的透光度和折射率变化,来定量研究不同辐射功率下牛晶状体的微波非热效应。研究表明S_(21)参数在一定程度上可以用来量化的表征处于不同状态的牛晶状体。并且微波辐射功率越大,晶状体受损程度越大,S_(21)参数变化也越大。为定量研究眼睛和微波生物非热效应提供一种研究途径,同时相关研究成果也为针对微波生物非热效应的安全标准制定提供重要的参考数据。
This project proposes to quantitatively express the nonthermal biological effects of microwave by measuring the variation of dielectric coefficient of biological tissue. Bovine lens is chosen as research objects. This project would design and development a set of dielectric coefficient measurement system and controlled microwave radiation equipment based on principle of microwave cancellation circuit. This project would set up the corresponding relation between the S_(21) and different radiation power. The results show that S_(21) could be used to quantitatively express the state of Bovine lens. Moreover, the larger the radiation power, the greater the impact on the health state of Bovine lens and S_(21). This project would provide a new research approach for quantitative research of nonthermal biological effects of microwave and provide important experimental and theoretical basis for the establishment of standards.
This project proposes to quantitatively express the nonthermal biological effects of microwave by measuring the variation of dielectric coefficient of biological tissue. Bovine lens is chosen as research objects. This project would design and development a set of dielectric coefficient measurement system and controlled microwave radiation equipment based on principle of microwave cancellation circuit. This project would set up the corresponding relation between the S_(21) and different radiation power. The results show that S_(21) could be used to quantitatively express the state of Bovine lens. Moreover, the larger the radiation power, the greater the impact on the health state of Bovine lens and S_(21). This project would provide a new research approach for quantitative research of nonthermal biological effects of microwave and provide important experimental and theoretical basis for the establishment of standards.
引文
[1] IEEE Standard. IEEE Standard for Safety Levels with Respect to Human Exposure to Radio Frequency Electromagnetic Fields, 3 kHz to 300 GHz-Amendment 1: Specifies Ceiling Limits for Induced and Contact Current, Clarifies Distinctions between Localized Exposure and Spatial Peak Power Density[J]. IEEE Std C95.1a-2010 (Amendment to IEEE Std C95.1-2005), 2010, C1-9.
[2] International Commission on Non-Ionizing Radiation Protection.Guidelines for limiting exposure to time-varying electric, magnetic and electromagnetic fields (up to 300 GHz)[J].Health Phys,1998(74):494-522.
[3] Dovrat A,Berenson R,Bormusov E,et al.Localized effects of microwave radiation on the intact eye lens in culture conditions[J].Bioelectromagnetics,2005(26),398-405.
[4] 黄卡玛,刘永清,唐敬贤,等.电磁波对化学反应的非热作用及其在电磁生物非热效应机理研究中的意义[J].微波学报,1996(2):126-132.
[5] Lan J,Hong T,Liang X,Du G.Evaluation of microwave microdosimetry for human eyes with glasses exposed to wireless eyewear devices at phone call state[J].Progress in Electromagnetics Research M,2018(63):71-81.
[6] 王保义,黄卡玛,徐润民,等.低强度微波辐射对人细胞非热生物效应的研究[J].中国医学物理学杂志,1995(1):9-14.
[7] World Health Organization.WHO research agenda for radiofrequency fields,2010.
[8] 夏玉静.小功率微波对人体健康影响的国内研究进展[J].中国职业医学,2001,28(2):49-50.
[9] Joines W T,Zhang Y,Li C,et al.The measured electrical properties of normal and malignant human tissues from 50 to 900 MHz[J].Medical physics,1994,21(4):547-550.
[10] Lan J Q,Liang X,Hong T,et al.On the effects of glasses on the SAR in human head resulting from wireless eyewear devices at phone call state[J]. Progress in Biophysics & Molecular Biology,2018(136):29-36.
[11] 严翠先,吴子俊,何烈纯.电子通讯设备微波作业人员眼晶状体的混浊状况[J].职业与健康,2010,26(1):32-33.
[2] International Commission on Non-Ionizing Radiation Protection.Guidelines for limiting exposure to time-varying electric, magnetic and electromagnetic fields (up to 300 GHz)[J].Health Phys,1998(74):494-522.
[3] Dovrat A,Berenson R,Bormusov E,et al.Localized effects of microwave radiation on the intact eye lens in culture conditions[J].Bioelectromagnetics,2005(26),398-405.
[4] 黄卡玛,刘永清,唐敬贤,等.电磁波对化学反应的非热作用及其在电磁生物非热效应机理研究中的意义[J].微波学报,1996(2):126-132.
[5] Lan J,Hong T,Liang X,Du G.Evaluation of microwave microdosimetry for human eyes with glasses exposed to wireless eyewear devices at phone call state[J].Progress in Electromagnetics Research M,2018(63):71-81.
[6] 王保义,黄卡玛,徐润民,等.低强度微波辐射对人细胞非热生物效应的研究[J].中国医学物理学杂志,1995(1):9-14.
[7] World Health Organization.WHO research agenda for radiofrequency fields,2010.
[8] 夏玉静.小功率微波对人体健康影响的国内研究进展[J].中国职业医学,2001,28(2):49-50.
[9] Joines W T,Zhang Y,Li C,et al.The measured electrical properties of normal and malignant human tissues from 50 to 900 MHz[J].Medical physics,1994,21(4):547-550.
[10] Lan J Q,Liang X,Hong T,et al.On the effects of glasses on the SAR in human head resulting from wireless eyewear devices at phone call state[J]. Progress in Biophysics & Molecular Biology,2018(136):29-36.
[11] 严翠先,吴子俊,何烈纯.电子通讯设备微波作业人员眼晶状体的混浊状况[J].职业与健康,2010,26(1):32-33.