植物多糖消化酵解特性的研究进展
|
摘要
植物多糖是植物中重要的组成物质,具有多种生物活性,在人类健康中起着重要的作用。植物多糖在体外发挥的生物活性与其结构有关,植物多糖在体内发挥的生物活性不但与其结构有关还与其被消化、酵解和吸收的过程有关,许多植物多糖在经过人体消化酵解被吸收后进入细胞内发挥作用。本文以植物多糖分类、结构、消化酵解吸收为主线,对近年来国内外植物多糖的结构与功能关系以及植物多糖消化酵解特性的研究进行综述,为植物多糖进一步的研究和开发提供一定的科学指导。
Plant polysaccharides were an important component in plants.They had many biological activities and played an important role in human health.The biological activity of plant polysaccharides in vitro were related to its structure.The biological activity of plant polysaccharides in vivo were related not only to its structure but also to the process of digestion,fermentation and absorption.Many plant polysaccharides had biological activities when they were absorbed into the cells after digestion or fermentation.In this review,the key point was the classification,structural property,digestion,fermentation and absorption of plant polysaccharides,and the studies on its structure-activity relationship,digestive and fermentative characteristics were summarized in recent years.The results would provide a certain scientific guidance for the further in-depth research and development of plant polysaccharides.
Plant polysaccharides were an important component in plants.They had many biological activities and played an important role in human health.The biological activity of plant polysaccharides in vitro were related to its structure.The biological activity of plant polysaccharides in vivo were related not only to its structure but also to the process of digestion,fermentation and absorption.Many plant polysaccharides had biological activities when they were absorbed into the cells after digestion or fermentation.In this review,the key point was the classification,structural property,digestion,fermentation and absorption of plant polysaccharides,and the studies on its structure-activity relationship,digestive and fermentative characteristics were summarized in recent years.The results would provide a certain scientific guidance for the further in-depth research and development of plant polysaccharides.
引文
[1]王丽颖,李福香,杨雅轩,等.多糖与多酚相互作用机制及其对多酚特性的影响研究进展[J].食品科学,2017,38(11):276-282.
[2]Chen Chun,You Li-jun,Abbasi A M,et al.Characterization of polysaccharide fractions in mulberry fruit and assessment of their antioxidant and hypoglycemic activities in vitro[J].Food&Function,2016,7(1):530-539.
[3]梅林,杜津昊,刘建飞,等.枸杞硒多糖的合成及对人体肝癌Hep G2细胞增殖的体外抑制作用评价[J].食品工业科技,2018,39(11):22-27.
[4]Asker M,Asker S F,Mohamed F M,et al.Chemical structure and antiviral activity of water-soluble sulfated polysaccharides from surgassum latifolium[J].Journal of Applied Sciences Research,2007,3(10):1178-1185.
[5]滕杨,王易男,刘冰雪,等.甘草硒多糖对CCl4诱导的小鼠急性肝损伤的影响作用[J].食品工业科技,2017,38(15):311-313.
[6]Zhang Ya-li,Zhang Jian-bao,Mo Xiao-yan,et al.Modification,characterization and structure-anticoagulant activity relationships of persimmon polysaccharides[J].Carbohydrate Polymers,2010,82(2):515-520.
[7]Wang Jun-long,Zhang Ji,Zhao Bao-tang,et al.Structural features and hypoglycaemic effects of Cynomorium songaricum polysaccharides on STZ-induced rats[J].Food Chemistry,2010,120(2):443-451.
[8]Zeng Hong-liang,Miao Song,Zhang Yi,et al.Isolation,preliminary structural characterization and hypolipidemic effect of polysaccharide fractions from Fortunella margarita(Lour.)Swingle[J].Food Hydrocolloids,2016,52:126-136.
[9]缪月秋,吴婷,张卫明,等.胡芦巴多糖酸解和酶解产物对肠道菌群体外生长影响的实验研究[J].食品工业科技,2007(7):62-64.
[10]姚瑞祺,刘海英,牛鹏飞,等.不同分子量枸杞多糖的超滤法分离及抗氧化活性研究[J].食品工业科技,2008,129(5):89-91.
[11]Olafsdottir E S,Omarsdottir S,Paulsen B S,et al.Rhamnopyranosylgalactofuranan,a new immunologically active polysaccharide from Thamnolia subuliformis[J].Phytomedicine:International Journal of Phytotherapy and Phytopharmacology,1999,6(4):273-279.
[12]谭西,周欣,陈华国.植物多糖构效关系研究进展[J].中国中药杂志,2017,42(21):4104-4109.
[13]陈燊.橄榄多糖提取分离及其功能特性的研究[D].福州:福建农林大学,2014.
[14]刘敏.玉竹水溶性多糖的提取动力学模型及一级结构鉴定研究[D].广州:广东药学院,2015.
[15]唐洁.植物多糖生物活性功能的研究进展[J].食品研究与开发,2006,127(5):130-132.
[16]Rytioja J,Hilden K,Yuzon J,et al.Plant-polysaccharidedegrading enzymes from basidiomycetes[J].Microbiology and Molecular Biology Reviews,2014,78(4):614-649.
[17]聂少平,黄丹菲,殷军艺,等.食物中多糖组分的结构表征与活性功能研究进展[J].中国食品学报,2011,11(9):46-57.
[18]何余堂,潘孝明.植物多糖的结构与活性研究进展[J].食品科学,2010,31(17):493-496.
[19]Zeng Hong-liang,Chen Pei-lin,Huang Can-can,et al.Structural features and biological activities of bioactive compounds from Fortunella margarita(Lour.)Swingle:A Review[J].Chinese Journal of Structural Chemistry,2017,36(12):2123-2132.
[20]Zeng Hong-liang,Zhang Yi,Zhao Ying-ting,et al.Extraction optimization,structure and antioxidant activities of Fortunella margarita Swingle polysaccharides[J].International Journal of Biological Macromolecules,2015,74:232-242.
[21]潘炎,陶雪,梁爽,等.五味子酸性多糖分级产物对小鼠急性酒精性肝损伤的改善作用[J].食品工业科技,2018,39(14):1-10.
[22]曾红亮.金柑多糖结构表征及降血脂机理的研究[D].福州:福建农林大学,2015.
[23]李明智,童微,胡婕伦,等.铁皮石斛多糖不同级分的制备、性质分析及免疫调节活性比较[J].食品工业科技,2018,39(15):1-8.
[24]Kweon M H,Hwang H J,Sung H C.Isolation and characterization of anticomplementary beta-glucans from the shoots of bamboo Phyllostachys edulis[J].Planta Medica,2003,69(1):56-62.
[25]Bohn A J,Bemiller J.(1→3)-β-d-Glucans as biological response modifiers:a review of structure-functional activity relationships[J].Carbohydrate Polymers,1995,28(1):3-14.
[26]Chen Chun,You Li-jun,Abbasi A M,et al.Characterization of polysaccharide fractions in mulberry fruit and assessment of their antioxidant and hypoglycemic activities in vitro[J].Food&Function,2016,7(1):530-539.
[27]Zhang Min,Tang Xiu-li,Wang Fang,et al.Characterization of Lycium barbarum polysaccharide and its effect on human hepatoma cell[J].International Journal of Biological Macromolecules,2013,61(10):270-275.
[28]张晓曼,廖文锋,丛启飞,等.桑白皮水提取多糖组分的分离纯化和结构特征[J].化学学报,2013,71(5):722-728.
[29]Xiao Kai-jun,Zhang Lin,Liu Xiao-hong,et al.In vitro anti-tumor effects of chemically modified polysaccharides from cherokee rose fruit[J].International Journal of Food Engineering,2014,10(3):473-479.
[30]Pujol C A,Ray S,Ray B,et al.Antiviral activity against dengue virus of diverse classes of algal sulfated polysaccharides[J].International Journal of Biological Macromolecules,2012,51(4):412-416.
[31]侯圆圆,杨延超,徐德平.不同结构大麦多糖降血糖活性差异的研究[J].食品研究与开发,2016,37(2):44-47.
[32]Yang Jian-hong,Du Yu-min,Huang Rong-hua,et al.Chemical modification,characterization and structure-anticoagulant activity relationships of Chinese lacquer polysaccharides[J].International Journal of Biological Macromolecules,2002,31(1-3):55-62.
[33]Hu Jie-lun,Nie Shao-ping,Min Fang-fang,et al.Artificial simulated saliva,gastric and intestinal digestion of polysaccharide from the seeds of Plantago asiatica L.[J].Carbohydrate Polymers,2013,92(2):1143-1150.
[34]闵芳芳,聂少平,万宇俊,等.青钱柳多糖在体外消化模型中的消化与吸收[J].食品科学,2013,34(21):24-29.
[35]陈萍.茶叶非淀粉多糖的分离制备、功能特性及降糖机制研究[D].杭州:中国计量学院,2014.
[36]任贝贝.鼠尾藻多糖的提取分离、体外消化和酵解特征及其对肠道菌群的影响[D].广州:华南理工大学,2017.
[37]Carnachan S M,Bootten T J,Mishra S,et al.Effects of simulated digestion in vitro on cell wall polysaccharides from kiwifruit(Actinidia spp.)[J].Food Chemistry,2012,133(1):132-139.
[38]Sandberg A S,Ahderinne R,Andersson H,et al.The effect of citrus pectin on the absorption of nutrients in the small intestine[J].Human Nutrition-Clinical Nutrition,1983,37(3):171-183.
[39]肖霄.NSPs(非淀粉类多糖)在大鼠体内转化吸收机制的研究[D].福州:福州大学,2014.
[40]李凡.霍山石斛多糖消化稳定性研究[D].合肥:合肥工业大学,2015.
[41]邱霞.麒麟菜低分子海藻多糖的制备及其消化吸收与生物活性的研究[D].青岛:青岛大学,2013.
[42]史文涛.太子参抗T2DM多糖及递药轨迹研究[D].福州:福建中医药大学,2015.
[43]王伟.新疆芜菁多糖的分离纯化、结构表征及生物活性研究[D].南京:南京农业大学,2016.
[44]陈萍,张拥军,朱丽云,等.人工胃液作用抗氧化龙井茶多糖的体外模拟研究[J].中国食品学报,2014,14(10):35-41.
[45]张冠亚,黄晓君,聂少平,等.体外模拟3种消化液对铁皮石斛多糖的消化作用[J].食品科学,2014,35(23):279-283.
[46]袁清霞.桑叶多糖分离纯化、结构分析及生物活性研究[D].南京:南京农业大学,2016.
[47]刘恋.条斑紫菜中多糖的溶出动力学、模拟消化及生物活性[D].镇江:江苏大学,2017.
[48]胡婕伦.大粒车前子多糖体内外消化与酵解特征体系构建及其促进肠道健康的作用[D].南昌:南昌大学,2014.
[49]Chen Chun,Zhang Bin,Fu Xiong,et al.The digestibility of mulberry fruit polysaccharides and its impact on lipolysis under simulated saliva,gastric and intestinal conditions[J].Food Hydrocolloids,2016,58:171-178.
[50]Flint H J,Bayer E A,Rincon M T,et al.Polysaccharide utilization by gut bacteria:potential for new insights from genomic analysis[J].Nature Reviews Microbiology,2008,6(2):121-131.
[51]Holscher H D,Caporaso J G,Hooda S,et al.Fiber supplementation influences phylogenetic structure and functional capacity of the human intestinal microbiome:follow-up of a randomized controlled trial[J].American Journal of Clinical Nutrition,2015,101(1):55-64.
[52]Huang Ya-ling,Tsai Y H,Chow C J.Water-insoluble fiberrich fraction from pineapple peel improves intestinal function in hamsters:evidence from cecal and fecal indicators[J].Nutrition Research,2014,34(4):346-354.
[53]Azmi A,Mustafa S,Hashim D M,et al.Prebiotic activity of polysaccharides extracted from Gigantochloa levis(Buluh beting)shoots[J].Molecules,2012,17(2):1635-1651.
[54]刘丽莎,王锐,旭日花,等.白术多糖对益生菌的促生长作用及结构分析[J].食品科学,2010,31(19):124-128.
[55]Bao Chen,Zeng Hong-liang,Zhang Yi,et al.Structural characteristics and prebiotic effects of Semen coicis resistant starches(type 3)prepared by different methods[J].International Journal of Biological Macromolecules,2017,105:671-679.
[56]Zhang Yi,Zeng Hong-liang,Wang Yin,et al.Structural characteristics and crystalline properties of lotus seed resistant starch and its prebiotic effects[J].Food Chemistry,2014,155:311-318.
[57]Zeng Hong-liang,Chen Pei-lin,Chen Chuan-jie,et al.Structural properties and prebiotic activities of fractionated lotus seed resistant starches[J].Food Chemistry,2018,251:33-40.
[58]陈地灵,陈振兴,林励,等.巴戟多糖在体肠吸收机制的研究[J].中药新药与临床药理,2012,23(1):61-64.
[59]王彦荣.黄芪多糖小肠吸收机制研究[D].天津:天津大学,2007.
[60]Chen Bin-yan,Jia Xiang-ze,Miao Song,et al.Slowly digestible properties of lotus seed starch-glycerine monostearin complexes formed by high pressure homogenization[J].Food Chemistry,2018,252:115-125.(下转第页)
[61]Zhang Yi,Wang Yin,Zheng Bao-dong,et al.The in vitro effects of retrograded starch(resistant starch type 3)from lotus seed starch on the proliferation of Bifidobacterium adolescentis[J].Food&Function,2013,4(11):1609-1616.
[62]Rose D J,Demeo M T,Keshavarzian A,et al.Influence of dietary fiber on inflammatory bowel disease and colon cancer:Importance of fermentation pattern[J].Nutrition Reviews,2007,65(2):51-62.
[63]Perry R J,Peng Liang,Barry N A,et al.Acetate mediates a microbiome-brain-beta-cell axis to promote metabolic syndrome[J].Nature,2016,534(7606):213-217.
[64]汪颖.莲子抗性淀粉制备、性质及其对双歧杆菌增殖效应的研究[D].福州:福建农林大学,2013.
[65]Zeng Hong-liang,Huang Can-can,Lin Shan,et al.Lotus seed resistant starch regulates gut microbiota and increases shortchain fatty acids production and mineral absorption in mice[J].Journal of Agricultural and Food Chemistry,2017,65(42):9217-9225.
[66]Shang Qing-sen,Jiang Hao,Cai Chao,et al.Gut microbiota fermentation of marine polysaccharides and its effects on intestinal ecology:An overview[J].Carbohydrate Polymers,2018,179:173-185.
[2]Chen Chun,You Li-jun,Abbasi A M,et al.Characterization of polysaccharide fractions in mulberry fruit and assessment of their antioxidant and hypoglycemic activities in vitro[J].Food&Function,2016,7(1):530-539.
[3]梅林,杜津昊,刘建飞,等.枸杞硒多糖的合成及对人体肝癌Hep G2细胞增殖的体外抑制作用评价[J].食品工业科技,2018,39(11):22-27.
[4]Asker M,Asker S F,Mohamed F M,et al.Chemical structure and antiviral activity of water-soluble sulfated polysaccharides from surgassum latifolium[J].Journal of Applied Sciences Research,2007,3(10):1178-1185.
[5]滕杨,王易男,刘冰雪,等.甘草硒多糖对CCl4诱导的小鼠急性肝损伤的影响作用[J].食品工业科技,2017,38(15):311-313.
[6]Zhang Ya-li,Zhang Jian-bao,Mo Xiao-yan,et al.Modification,characterization and structure-anticoagulant activity relationships of persimmon polysaccharides[J].Carbohydrate Polymers,2010,82(2):515-520.
[7]Wang Jun-long,Zhang Ji,Zhao Bao-tang,et al.Structural features and hypoglycaemic effects of Cynomorium songaricum polysaccharides on STZ-induced rats[J].Food Chemistry,2010,120(2):443-451.
[8]Zeng Hong-liang,Miao Song,Zhang Yi,et al.Isolation,preliminary structural characterization and hypolipidemic effect of polysaccharide fractions from Fortunella margarita(Lour.)Swingle[J].Food Hydrocolloids,2016,52:126-136.
[9]缪月秋,吴婷,张卫明,等.胡芦巴多糖酸解和酶解产物对肠道菌群体外生长影响的实验研究[J].食品工业科技,2007(7):62-64.
[10]姚瑞祺,刘海英,牛鹏飞,等.不同分子量枸杞多糖的超滤法分离及抗氧化活性研究[J].食品工业科技,2008,129(5):89-91.
[11]Olafsdottir E S,Omarsdottir S,Paulsen B S,et al.Rhamnopyranosylgalactofuranan,a new immunologically active polysaccharide from Thamnolia subuliformis[J].Phytomedicine:International Journal of Phytotherapy and Phytopharmacology,1999,6(4):273-279.
[12]谭西,周欣,陈华国.植物多糖构效关系研究进展[J].中国中药杂志,2017,42(21):4104-4109.
[13]陈燊.橄榄多糖提取分离及其功能特性的研究[D].福州:福建农林大学,2014.
[14]刘敏.玉竹水溶性多糖的提取动力学模型及一级结构鉴定研究[D].广州:广东药学院,2015.
[15]唐洁.植物多糖生物活性功能的研究进展[J].食品研究与开发,2006,127(5):130-132.
[16]Rytioja J,Hilden K,Yuzon J,et al.Plant-polysaccharidedegrading enzymes from basidiomycetes[J].Microbiology and Molecular Biology Reviews,2014,78(4):614-649.
[17]聂少平,黄丹菲,殷军艺,等.食物中多糖组分的结构表征与活性功能研究进展[J].中国食品学报,2011,11(9):46-57.
[18]何余堂,潘孝明.植物多糖的结构与活性研究进展[J].食品科学,2010,31(17):493-496.
[19]Zeng Hong-liang,Chen Pei-lin,Huang Can-can,et al.Structural features and biological activities of bioactive compounds from Fortunella margarita(Lour.)Swingle:A Review[J].Chinese Journal of Structural Chemistry,2017,36(12):2123-2132.
[20]Zeng Hong-liang,Zhang Yi,Zhao Ying-ting,et al.Extraction optimization,structure and antioxidant activities of Fortunella margarita Swingle polysaccharides[J].International Journal of Biological Macromolecules,2015,74:232-242.
[21]潘炎,陶雪,梁爽,等.五味子酸性多糖分级产物对小鼠急性酒精性肝损伤的改善作用[J].食品工业科技,2018,39(14):1-10.
[22]曾红亮.金柑多糖结构表征及降血脂机理的研究[D].福州:福建农林大学,2015.
[23]李明智,童微,胡婕伦,等.铁皮石斛多糖不同级分的制备、性质分析及免疫调节活性比较[J].食品工业科技,2018,39(15):1-8.
[24]Kweon M H,Hwang H J,Sung H C.Isolation and characterization of anticomplementary beta-glucans from the shoots of bamboo Phyllostachys edulis[J].Planta Medica,2003,69(1):56-62.
[25]Bohn A J,Bemiller J.(1→3)-β-d-Glucans as biological response modifiers:a review of structure-functional activity relationships[J].Carbohydrate Polymers,1995,28(1):3-14.
[26]Chen Chun,You Li-jun,Abbasi A M,et al.Characterization of polysaccharide fractions in mulberry fruit and assessment of their antioxidant and hypoglycemic activities in vitro[J].Food&Function,2016,7(1):530-539.
[27]Zhang Min,Tang Xiu-li,Wang Fang,et al.Characterization of Lycium barbarum polysaccharide and its effect on human hepatoma cell[J].International Journal of Biological Macromolecules,2013,61(10):270-275.
[28]张晓曼,廖文锋,丛启飞,等.桑白皮水提取多糖组分的分离纯化和结构特征[J].化学学报,2013,71(5):722-728.
[29]Xiao Kai-jun,Zhang Lin,Liu Xiao-hong,et al.In vitro anti-tumor effects of chemically modified polysaccharides from cherokee rose fruit[J].International Journal of Food Engineering,2014,10(3):473-479.
[30]Pujol C A,Ray S,Ray B,et al.Antiviral activity against dengue virus of diverse classes of algal sulfated polysaccharides[J].International Journal of Biological Macromolecules,2012,51(4):412-416.
[31]侯圆圆,杨延超,徐德平.不同结构大麦多糖降血糖活性差异的研究[J].食品研究与开发,2016,37(2):44-47.
[32]Yang Jian-hong,Du Yu-min,Huang Rong-hua,et al.Chemical modification,characterization and structure-anticoagulant activity relationships of Chinese lacquer polysaccharides[J].International Journal of Biological Macromolecules,2002,31(1-3):55-62.
[33]Hu Jie-lun,Nie Shao-ping,Min Fang-fang,et al.Artificial simulated saliva,gastric and intestinal digestion of polysaccharide from the seeds of Plantago asiatica L.[J].Carbohydrate Polymers,2013,92(2):1143-1150.
[34]闵芳芳,聂少平,万宇俊,等.青钱柳多糖在体外消化模型中的消化与吸收[J].食品科学,2013,34(21):24-29.
[35]陈萍.茶叶非淀粉多糖的分离制备、功能特性及降糖机制研究[D].杭州:中国计量学院,2014.
[36]任贝贝.鼠尾藻多糖的提取分离、体外消化和酵解特征及其对肠道菌群的影响[D].广州:华南理工大学,2017.
[37]Carnachan S M,Bootten T J,Mishra S,et al.Effects of simulated digestion in vitro on cell wall polysaccharides from kiwifruit(Actinidia spp.)[J].Food Chemistry,2012,133(1):132-139.
[38]Sandberg A S,Ahderinne R,Andersson H,et al.The effect of citrus pectin on the absorption of nutrients in the small intestine[J].Human Nutrition-Clinical Nutrition,1983,37(3):171-183.
[39]肖霄.NSPs(非淀粉类多糖)在大鼠体内转化吸收机制的研究[D].福州:福州大学,2014.
[40]李凡.霍山石斛多糖消化稳定性研究[D].合肥:合肥工业大学,2015.
[41]邱霞.麒麟菜低分子海藻多糖的制备及其消化吸收与生物活性的研究[D].青岛:青岛大学,2013.
[42]史文涛.太子参抗T2DM多糖及递药轨迹研究[D].福州:福建中医药大学,2015.
[43]王伟.新疆芜菁多糖的分离纯化、结构表征及生物活性研究[D].南京:南京农业大学,2016.
[44]陈萍,张拥军,朱丽云,等.人工胃液作用抗氧化龙井茶多糖的体外模拟研究[J].中国食品学报,2014,14(10):35-41.
[45]张冠亚,黄晓君,聂少平,等.体外模拟3种消化液对铁皮石斛多糖的消化作用[J].食品科学,2014,35(23):279-283.
[46]袁清霞.桑叶多糖分离纯化、结构分析及生物活性研究[D].南京:南京农业大学,2016.
[47]刘恋.条斑紫菜中多糖的溶出动力学、模拟消化及生物活性[D].镇江:江苏大学,2017.
[48]胡婕伦.大粒车前子多糖体内外消化与酵解特征体系构建及其促进肠道健康的作用[D].南昌:南昌大学,2014.
[49]Chen Chun,Zhang Bin,Fu Xiong,et al.The digestibility of mulberry fruit polysaccharides and its impact on lipolysis under simulated saliva,gastric and intestinal conditions[J].Food Hydrocolloids,2016,58:171-178.
[50]Flint H J,Bayer E A,Rincon M T,et al.Polysaccharide utilization by gut bacteria:potential for new insights from genomic analysis[J].Nature Reviews Microbiology,2008,6(2):121-131.
[51]Holscher H D,Caporaso J G,Hooda S,et al.Fiber supplementation influences phylogenetic structure and functional capacity of the human intestinal microbiome:follow-up of a randomized controlled trial[J].American Journal of Clinical Nutrition,2015,101(1):55-64.
[52]Huang Ya-ling,Tsai Y H,Chow C J.Water-insoluble fiberrich fraction from pineapple peel improves intestinal function in hamsters:evidence from cecal and fecal indicators[J].Nutrition Research,2014,34(4):346-354.
[53]Azmi A,Mustafa S,Hashim D M,et al.Prebiotic activity of polysaccharides extracted from Gigantochloa levis(Buluh beting)shoots[J].Molecules,2012,17(2):1635-1651.
[54]刘丽莎,王锐,旭日花,等.白术多糖对益生菌的促生长作用及结构分析[J].食品科学,2010,31(19):124-128.
[55]Bao Chen,Zeng Hong-liang,Zhang Yi,et al.Structural characteristics and prebiotic effects of Semen coicis resistant starches(type 3)prepared by different methods[J].International Journal of Biological Macromolecules,2017,105:671-679.
[56]Zhang Yi,Zeng Hong-liang,Wang Yin,et al.Structural characteristics and crystalline properties of lotus seed resistant starch and its prebiotic effects[J].Food Chemistry,2014,155:311-318.
[57]Zeng Hong-liang,Chen Pei-lin,Chen Chuan-jie,et al.Structural properties and prebiotic activities of fractionated lotus seed resistant starches[J].Food Chemistry,2018,251:33-40.
[58]陈地灵,陈振兴,林励,等.巴戟多糖在体肠吸收机制的研究[J].中药新药与临床药理,2012,23(1):61-64.
[59]王彦荣.黄芪多糖小肠吸收机制研究[D].天津:天津大学,2007.
[60]Chen Bin-yan,Jia Xiang-ze,Miao Song,et al.Slowly digestible properties of lotus seed starch-glycerine monostearin complexes formed by high pressure homogenization[J].Food Chemistry,2018,252:115-125.(下转第页)
[61]Zhang Yi,Wang Yin,Zheng Bao-dong,et al.The in vitro effects of retrograded starch(resistant starch type 3)from lotus seed starch on the proliferation of Bifidobacterium adolescentis[J].Food&Function,2013,4(11):1609-1616.
[62]Rose D J,Demeo M T,Keshavarzian A,et al.Influence of dietary fiber on inflammatory bowel disease and colon cancer:Importance of fermentation pattern[J].Nutrition Reviews,2007,65(2):51-62.
[63]Perry R J,Peng Liang,Barry N A,et al.Acetate mediates a microbiome-brain-beta-cell axis to promote metabolic syndrome[J].Nature,2016,534(7606):213-217.
[64]汪颖.莲子抗性淀粉制备、性质及其对双歧杆菌增殖效应的研究[D].福州:福建农林大学,2013.
[65]Zeng Hong-liang,Huang Can-can,Lin Shan,et al.Lotus seed resistant starch regulates gut microbiota and increases shortchain fatty acids production and mineral absorption in mice[J].Journal of Agricultural and Food Chemistry,2017,65(42):9217-9225.
[66]Shang Qing-sen,Jiang Hao,Cai Chao,et al.Gut microbiota fermentation of marine polysaccharides and its effects on intestinal ecology:An overview[J].Carbohydrate Polymers,2018,179:173-185.