17722例孕妇四种传染病感染指标检测结果分析
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摘要
目的分析孕妇产前血液传染标志物检测的临床意义。方法回顾性分析南方医科大学南海医院2014年1月至2016年12月收治的17 722例孕妇产前乙型肝炎病毒表面抗原(HBsAg)、丙型肝炎病毒抗体(抗-HCV)、人类免疫缺陷病毒抗体(抗-HIV)、梅毒(抗-TP)等4项血液传染标志物的检测结果。结果 HBsAg阳性率为5.46%(967/17 722);抗-HCV阳性率为0.20%(36/17 722);抗-HIV阳性率为0.05%(9/17 722);梅毒感染阳性率为1.00%(178/17 722)。结论孕妇产前检测4项传染标志物对阻断和降低感染性疾病的母婴传播、避免医疗纠纷、预防医院感染等具有重要意义。
Objective To investigate the clinical significance of the blood infection markers detection in pregnant women before delivery. Methods The clinical data of hepatitis B surface antigen(HBsAg), hepatitis C virus(HCV) antibody, human immunodeficiency virus(HIV) antibody and Treponema pallidum(TP) antibody of 17 722 cases pregnant women, who admitted to Department of Clinical Laboratory of Nanhai Hospital of Southern Medical University from Jan. 2014 to Dec. 2016, were retrospectively analyzed. Results Among 17 722 cases of pregnant women, the positive rate of HBsAg was 5.46%(967/17 722), that of HCV antibody positive rates was 0.20%(36/17 722), and that of HIV antibody and TP antibody were 0.05%(9/17 722) and 1.00%(178/17 722), respectively. Conclusion The prenatal detection of four infection markers in pregnant women is of great significance in blocking and reducing mother-tochild transmission of infectious diseases, avoiding medical disputes and preventing hospital infection.
Objective To investigate the clinical significance of the blood infection markers detection in pregnant women before delivery. Methods The clinical data of hepatitis B surface antigen(HBsAg), hepatitis C virus(HCV) antibody, human immunodeficiency virus(HIV) antibody and Treponema pallidum(TP) antibody of 17 722 cases pregnant women, who admitted to Department of Clinical Laboratory of Nanhai Hospital of Southern Medical University from Jan. 2014 to Dec. 2016, were retrospectively analyzed. Results Among 17 722 cases of pregnant women, the positive rate of HBsAg was 5.46%(967/17 722), that of HCV antibody positive rates was 0.20%(36/17 722), and that of HIV antibody and TP antibody were 0.05%(9/17 722) and 1.00%(178/17 722), respectively. Conclusion The prenatal detection of four infection markers in pregnant women is of great significance in blocking and reducing mother-tochild transmission of infectious diseases, avoiding medical disputes and preventing hospital infection.
引文
[1]周玉平,朱传新,陈桃珍,等. 12 301名孕妇相关传染病指标检测结果分析[J].中华传染病杂志, 2013, 31(9):557-560.
[2]燕虹,李十月.艾滋病,梅毒和乙肝母婴传播阻断项目的思考[J].公共卫生与预防医学, 2014, 25(4):1-3.
[3]李庆.孕妇产前四项传染病指标检测结果的分析[J].中华室验和临床感染病杂志(电子版). 2014, 8(2):98-100.
[4] VRYHEID RE, KANE MA, MULLER N, et al. Infant and adolescent hepatitis B immunization up to 1999:a global overview[J]. Vac-cine, 2000, 19(9-10):1026-1037.
[5] BEUTELS D. Economic evaluation of hepatitis B immunization:a global review of recent studies(1994-2000)[J]. Health Econ, 2001,10(8):751-774.
[6]黄新海,曾成林,欧桂珍.产前5项感染性指标检查的分析[J].检验医学与临床, 2013, 10(8):1012-1013.
[7]张茜,徐永妮,胡建华.妊娠妇女产前感染4项检测结果分析[J].检验医学与临床, 2013, 10(13):295-296.
[8]梁培松,孙长青,王结珍,等. 6 930例孕妇4中传染病检测结果分析[J].国际检验医学杂志, 2017, 38(19):2753-2755.
[9]杨旭红,陈佳玉,王瑛坚,等.丙肝病毒的母婴传播诊断分析[J].中国实验诊断学, 2017, 21(4):659-660.
[10]周明书,李振华,伊诺,等.丙型肝炎病毒母婴传播率及高危因素的研究[J/CD].中华实验和临床感染病杂志(电子版), 2015, 9(4):474-477.
[11]彭江游,谢家宁.孕妇感染性疾病血清标志物检查及临床探讨[J].检验医学与临床, 2017, 14(2):222-226.
[12]徐亿力,陈娅莉,喻彬,等.梅毒感染孕妇结局调查研究[J].中华医院感染学杂志, 2015, 25(19):4528-4530.
[13]徐美凤,魏青,何婷,等.梅毒孕妇抗梅毒治疗时机对新生儿梅毒感染的影响研究[J].中华医院感染学杂志, 2017, 27(6):1387-1390.
[14]李海素,谭冲,曹刚,等.妊娠梅毒母婴传播的相关因素分析[J].中国妇幼保健, 2012, 27(10):1496-1497.
[15]杨慧.孕妇4 199例4种传染病感染指标检测结果分析[J].上海预防医学, 2013, 25(1):17-18.
[16]徐洁,刘艳.社区人类免疫缺陷病毒母婴健康教育对预防孕妇艾滋病感染的预警效果分析[J].广东医学, 2014, 35(9):1408-1410.
[17]蒲杰,梁家智.预防艾滋病母婴传播的研究进展[J].现代预防医学,2013, 40(6):1122-1124
[18]李庆.孕妇产前四项传染病指标检测结果分析[J/CD].中华实验和临床感染病杂志(电子版), 2014, 8(2):98-100.
[19]陈娟,左娟.福安地区孕妇产前母婴传播性疾病标志物的分析[J].实验与检验医学, 2015, 12(6):754-756.
[2]燕虹,李十月.艾滋病,梅毒和乙肝母婴传播阻断项目的思考[J].公共卫生与预防医学, 2014, 25(4):1-3.
[3]李庆.孕妇产前四项传染病指标检测结果的分析[J].中华室验和临床感染病杂志(电子版). 2014, 8(2):98-100.
[4] VRYHEID RE, KANE MA, MULLER N, et al. Infant and adolescent hepatitis B immunization up to 1999:a global overview[J]. Vac-cine, 2000, 19(9-10):1026-1037.
[5] BEUTELS D. Economic evaluation of hepatitis B immunization:a global review of recent studies(1994-2000)[J]. Health Econ, 2001,10(8):751-774.
[6]黄新海,曾成林,欧桂珍.产前5项感染性指标检查的分析[J].检验医学与临床, 2013, 10(8):1012-1013.
[7]张茜,徐永妮,胡建华.妊娠妇女产前感染4项检测结果分析[J].检验医学与临床, 2013, 10(13):295-296.
[8]梁培松,孙长青,王结珍,等. 6 930例孕妇4中传染病检测结果分析[J].国际检验医学杂志, 2017, 38(19):2753-2755.
[9]杨旭红,陈佳玉,王瑛坚,等.丙肝病毒的母婴传播诊断分析[J].中国实验诊断学, 2017, 21(4):659-660.
[10]周明书,李振华,伊诺,等.丙型肝炎病毒母婴传播率及高危因素的研究[J/CD].中华实验和临床感染病杂志(电子版), 2015, 9(4):474-477.
[11]彭江游,谢家宁.孕妇感染性疾病血清标志物检查及临床探讨[J].检验医学与临床, 2017, 14(2):222-226.
[12]徐亿力,陈娅莉,喻彬,等.梅毒感染孕妇结局调查研究[J].中华医院感染学杂志, 2015, 25(19):4528-4530.
[13]徐美凤,魏青,何婷,等.梅毒孕妇抗梅毒治疗时机对新生儿梅毒感染的影响研究[J].中华医院感染学杂志, 2017, 27(6):1387-1390.
[14]李海素,谭冲,曹刚,等.妊娠梅毒母婴传播的相关因素分析[J].中国妇幼保健, 2012, 27(10):1496-1497.
[15]杨慧.孕妇4 199例4种传染病感染指标检测结果分析[J].上海预防医学, 2013, 25(1):17-18.
[16]徐洁,刘艳.社区人类免疫缺陷病毒母婴健康教育对预防孕妇艾滋病感染的预警效果分析[J].广东医学, 2014, 35(9):1408-1410.
[17]蒲杰,梁家智.预防艾滋病母婴传播的研究进展[J].现代预防医学,2013, 40(6):1122-1124
[18]李庆.孕妇产前四项传染病指标检测结果分析[J/CD].中华实验和临床感染病杂志(电子版), 2014, 8(2):98-100.
[19]陈娟,左娟.福安地区孕妇产前母婴传播性疾病标志物的分析[J].实验与检验医学, 2015, 12(6):754-756.