正常肝脏、胰腺、脾脏双源CT碘含量测量的初探
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摘要
目的:使用双源CT双能量扫描,探讨正常肝脏、胰腺、脾脏的碘含量特征,建立正常肝脏、胰腺、脾脏的碘含量参考值。方法:对54例非器质性疾病患者行双源CT双能量双期增强扫描。使用Siemens Dual Energy-Liver VNC图像处理软件对动脉晚期、门静脉期0.7mm图像进行分析处理。测量肝脏、胰腺(胰头、胰体、胰尾)、脾脏及腹主动脉(腹腔干开口的上一层面)的含碘值,并计算标化含碘值(nIC)。结果:正常肝脏在动脉晚期和门脉期的nIC值分别为0.10±0.09和0.40±0.09;正常胰腺各部位在动脉晚期的nIC值分别为0.29±0.32(胰头)、0.29±0.31(胰体)和0.28±0.35(胰尾),在门脉期分别为0.49±0.21(胰头)、0.46±0.17(胰体)和0.46±0.16(胰尾);正常脾脏在门脉期的nIC值为0.02±0.05。不同年龄、不同性别组间正常肝脏、胰腺和脾脏nIC值的差异均无统计学意义(P>0.05);胰腺不同部位nIC值的差异无统计学意义(P>0.05);不同扫描期相肝脏nIC值的差异有统计学意义(P<0.05)。结论:双源CT扫描可获得正常肝脏、胰腺、脾脏的碘含量,可为肝脏、胰腺及脾脏疾病的诊断提供参考。
Objective:To analyze the characteristics of iodine distribution in normal liver,pancreas and spleen,and to establish the normal reference value of iodine content in these organs by using dual energy CT.Methods:54adults without organic disease were recruited and underwent dual energy CT examination.The Siemens Dual Energy software was used to analyze the iodine content of normal liver,pancreas and spleen in late arterial and portal venous phase.The iodine concentration in aorta,liver,pancreas and spleen were measured on the iodine-based material-decomposition images,and were further normalized(nIC)and compared.Results:The nIC of liver in late arterial and portal venous phase was 0.10±0.09and0.40±0.09,respectively;the nIC in head,body,and tail of pancreas was 0.29±0.32,0.29±0.31 and 0.28±0.3in late arterial phase,and 0.49±0.21,0.46±0.17 and 0.46±0.16 in portal venous phase;the nIC of spleen in portal venous phase was 0.02±0.05.There were no significant differences of nIC in liver,pancreas(head,body,tail)and spleen between gender and different age groups(P>0.05).The nICs of liver in the two phases were statistically different(P<0.05).There were no significant differences among the nICs of pancreatic head,body and tail(P<0.05).Conclusion:The information of iodine content of liver,pancreas and spleen can be provided by dual energy CT scan,which is helpful for the diagnosis of lesions in these organs.
Objective:To analyze the characteristics of iodine distribution in normal liver,pancreas and spleen,and to establish the normal reference value of iodine content in these organs by using dual energy CT.Methods:54adults without organic disease were recruited and underwent dual energy CT examination.The Siemens Dual Energy software was used to analyze the iodine content of normal liver,pancreas and spleen in late arterial and portal venous phase.The iodine concentration in aorta,liver,pancreas and spleen were measured on the iodine-based material-decomposition images,and were further normalized(nIC)and compared.Results:The nIC of liver in late arterial and portal venous phase was 0.10±0.09and0.40±0.09,respectively;the nIC in head,body,and tail of pancreas was 0.29±0.32,0.29±0.31 and 0.28±0.3in late arterial phase,and 0.49±0.21,0.46±0.17 and 0.46±0.16 in portal venous phase;the nIC of spleen in portal venous phase was 0.02±0.05.There were no significant differences of nIC in liver,pancreas(head,body,tail)and spleen between gender and different age groups(P>0.05).The nICs of liver in the two phases were statistically different(P<0.05).There were no significant differences among the nICs of pancreatic head,body and tail(P<0.05).Conclusion:The information of iodine content of liver,pancreas and spleen can be provided by dual energy CT scan,which is helpful for the diagnosis of lesions in these organs.
引文
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[3]齐晓辉,时高峰,王琦,等.炫速双源CT双能量虚拟平扫在肝脏扫描应用的初步研究[J].实用放射学杂志,2013,29(3):396-399,432.
[4]胡奕,郭启勇.双源CT双能量扫描技术在腹部的应用[J].中国临床医学影像杂志,2011,22(2):108-111.
[5]Petersilka M,Bruder H,Krauss B,et al.Technical principles of dual source CT[J].Eur J Radiol,2008,68(3):362-368.
[6]秦维昌.双源双能量CT成像的技术进展[J].中国医疗设备,2012,27(3):61-61,76.
[7]Kang MJ,Park CM,Lee CH,et al.Dual-energy CT:clinical applications in various pulmonary diseases[J].Radiographics,2010,30(3):685-698.
[8]薛华丹,刘炜,孙昊,等.第二代双源CT双能扫描模式对胰腺癌的影像诊断价值初探[J].中国医学科学院学报,2010,32(6):640-644.
[9]袁元,黄子星,李真林,等.双源CT双能量碘图对急性坏死性胰腺炎影像的诊断价值[J].四川大学学报(医学版),2012,43(4):697-600.
[10]白人驹,马大庆,张雪林,等.医学影像诊断学[M].北京,人民卫生出版社,2005:448-449.
[11]王化,王伟,唐光健.肝细胞癌影像学诊断的现状与进展[J].中华放射学杂志,2006,40(3):315-318.
[12]Efremidis SC,Hytrioglou P.The multistep process of hepatocarcinogenesis in cirrhosis with imaging correlation[J].Eur Radiol,2002,2(4):753-764.
[13]Kudo M.Multistep human hepatocarcinogenesis:correlation of imaging with pathology[J].Gastroenterol,2009,44(19):112-118.
[14]Kitao A,Zen Y,Matsui O,et al.Hepatocarcinogenesis:multistep changes of drainage vessels at CT during arterial portography and hepatic arteriography-radiologic-pathologic correlation[J].Radiology,2009,252(2):605-614.
[15]Tajima T,Honda H,Taguchi L,et al.Sequential hemodynamic change in hepatocellular carcinoma and dysplastic nodules:CT angiography and pathologic correlation[J].AJR,2001,178(4):885-897.
[16]Nascimento C,Bottino A,nogueira C,et al.Analysis of morphological variables and arterialization in the differential of hepatic nodules in explanted cirrhotic livers[J].Diagn Pathol,2007,21(12):51-65.
[17]左玉江,王成林.脾脏CT灌注技术[J].罕见疾病杂志,2009,16(5):39-41.
[18]卢光明,张龙江.双能量CT何去何从[J].放射学实践,2014,29,(9):986-987.