蔡淦膏方治疗功能性便秘用药规律数据挖掘研究
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摘要
目的探讨膏方治疗功能性便秘(FC)的用药规律。方法收集2016—2018年蔡淦教授膏方门诊FC患者137例的处方,统计常见药物频率,并运用SPSS modeler18.0的Apriori算法进行关联分析,得出不同组合的用药规律。结果出现频率较高的5味中药依次为木香、生甘草、茯苓、太子参、陈皮,药物组合常用的5组为半夏与陈皮、砂仁与木香、豆蔻与木香、豆蔻与砂仁、生白术与生甘草。结论蔡淦教授运用膏方治疗FC重视从脾胃论治,以健脾助运为主,随证配伍润肠通便、清热化湿、滋养阴津、活血化瘀、化痰导滞、补肾通便之法。
Objective To explore the medication rules of TCM ointment in the treatment of functional constipation.Methods From 2016 to 2018,137 prescriptions for functional constipation were collected from Professor Cai Gan's ointment outpatient department.The application frequency of commonly used herbal drugs was calculated and SPSS modeler 18.0 Apriori algorithm was used to analyze the usage of different drug combinations in the treatment of functional constipation.Results The most commonly used five Chinese herbs were:Radix Aucklandiae,Raw licorice,Poria cocos,Pseudostellaria principis,Orange peel;the most commonly used five groups of herbal medicines were Pinellia and Orange peel,Amomum villosum and Radix Aucklandiae,Amomum kravanh and Radix Aucklandiae,Amomum kravanh and Amomum villosu,Raw atractylodes and Licorice.Conclusion The ointment prescription in treating functional constipation attaches great importance to the care of the spleen and the stomach,strengthening spleen and helping transportation as the main method,and compatible with the Methods of moisturizing bowel,clearing heat and removing dampness,nourishing yin and fluid,promoting blood circulation and removing blood stasis,dissipating phlegm and removing stagnation,tonifying kidney and purgation.
Objective To explore the medication rules of TCM ointment in the treatment of functional constipation.Methods From 2016 to 2018,137 prescriptions for functional constipation were collected from Professor Cai Gan's ointment outpatient department.The application frequency of commonly used herbal drugs was calculated and SPSS modeler 18.0 Apriori algorithm was used to analyze the usage of different drug combinations in the treatment of functional constipation.Results The most commonly used five Chinese herbs were:Radix Aucklandiae,Raw licorice,Poria cocos,Pseudostellaria principis,Orange peel;the most commonly used five groups of herbal medicines were Pinellia and Orange peel,Amomum villosum and Radix Aucklandiae,Amomum kravanh and Radix Aucklandiae,Amomum kravanh and Amomum villosu,Raw atractylodes and Licorice.Conclusion The ointment prescription in treating functional constipation attaches great importance to the care of the spleen and the stomach,strengthening spleen and helping transportation as the main method,and compatible with the Methods of moisturizing bowel,clearing heat and removing dampness,nourishing yin and fluid,promoting blood circulation and removing blood stasis,dissipating phlegm and removing stagnation,tonifying kidney and purgation.
引文
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[2] 张鹤,白光.当前功能性便秘的中医药治疗概述[J].名医,2018(11):24,26.
[3] 周波.润肠通便膏治疗功能性便秘肠燥津亏证的临床疗效观察[D].广州:广州中医药大学,2017.
[4] Brian EL,Fermin M,Lin C,et al.Bowel Disorders[J].Gastroenterology,2016,150(6):1393-1407.
[5] Satish SC Rao,Adil EB,Giuseppe C,et al.Anorectal Disorders[J].Gastroenterology,2016,150(6):1430-1442.
[6] 张正利,朱梅萍,刘群.蔡淦教授诊治慢性便秘经验[J].河北中医,2005,27(9):645-646.
[7] 丛军.蔡淦辨证治疗功能性便秘经验[J].上海中医药杂志,2008,42(1):11-12.
[8] 林江,蔡淦.蔡淦治疗老年习惯性便秘的经验[J].上海中医药杂志,2005,39(12):26-27.
[9] 隋楠,田振国,鞠宝兆.基于大肠主津理论应用助阳通便膏方治疗功能性便秘[J].中华中医药杂志,2019,34(1):168-170.