探讨细胞块切片免疫组化染色在胸腔积液诊断中的价值
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摘要
目的探讨细胞块切片免疫组化染色在胸腔积液诊断中的应用价值。方法随机选定2016年2月—2018年2月本院收治的胸腔积液患者60例作为研究对象,以住院床号奇偶性分组,分试验组、对照组,每组样本容量30例。对照组采纳常规细胞涂片检测,试验组采纳常规细胞涂片检测与细胞块切片免疫组化染色检测,选用抗体包括TTF-1、NapsinA、BerEP4、CK7抗体,对比诊断阳性率。结果试验组的阳性率(100.00%)较对照组(83.33%)高,差异具有统计学意义(P <0.05)。结论细胞块切片免疫组化染色检测可以为胸腔积液患者疾病的诊断提供更为科学的依据,效果确切。
Objective To evaluate the value of immunohistochemical staining of cell block in the diagnosis of pleural effusion. Methods 60 patients with pleural effusion treated in our hospital from February 2016 to February 2018 were randomly selected as the research subjects. The patients were divided into the experimental group and the control group according to the parity number of the inpatient bed. The sample size of each group was 30 cases. The control group received routine cell smear test. Routine cell smear test and cell block sections immunohistochemical staining were used in the experimental group. Antibodies including TTF-1, NapsinA, BerEP4 and CK7 antibodies were selected, and the positive rate was compared. Results The positive rate of test group(100.00%) was higher than that of control group(83.33%). The difference was statistically significant(P <0.05). Conclusion The immunohistochemical staining of cell block can provide a more scientific basis for the diagnosis of pleural effusion disease. The effect is definite.
Objective To evaluate the value of immunohistochemical staining of cell block in the diagnosis of pleural effusion. Methods 60 patients with pleural effusion treated in our hospital from February 2016 to February 2018 were randomly selected as the research subjects. The patients were divided into the experimental group and the control group according to the parity number of the inpatient bed. The sample size of each group was 30 cases. The control group received routine cell smear test. Routine cell smear test and cell block sections immunohistochemical staining were used in the experimental group. Antibodies including TTF-1, NapsinA, BerEP4 and CK7 antibodies were selected, and the positive rate was compared. Results The positive rate of test group(100.00%) was higher than that of control group(83.33%). The difference was statistically significant(P <0.05). Conclusion The immunohistochemical staining of cell block can provide a more scientific basis for the diagnosis of pleural effusion disease. The effect is definite.
引文
[1]余卫东,蔡育波,刘琼茹,等.细胞块切片免疫组化染色在胸腔积液病理诊断中的应用[J].中国现代医生,2014,52(12):127-129.
[2]杨红敏,李振芬.细胞块切片免疫组化染色在胸腔积液病理诊断中的应用价值[J].中外医疗,2014,33(1):179.
[3]李中祥.细胞块切片免疫组化染色在胸腔积液病理诊断中的应用价值[J].河南医学研究,2015,24(4):88-89.
[4]吴家宁,杜芸,王珩,等.膜式细胞采集器在脱落细胞免疫组化染色中的临床应用[J].临床与实验病理学杂志,2014,30(6):694-696.
[5]姚岚.临床病理技术在胸腔积液细胞块中的应用[J].中国实用医刊,2016,43(6):101-102.
[6]黄其文,姜汉国.胸腔积液细胞块切片免疫组化染色技术鉴别诊断肺腺癌的临床研究[J].临床肺科杂志,2017,22(2):227-229.
[7]陈良娟.临床病理技术在胸腔积液中的应用研究[J].基层医学论坛,2017,21(20):2672-2673.
[8]沈湘萍,陈艳,张小伟.细胞块免疫组化在恶性小细胞肿瘤胸腔转移中的临床病理分析[J].现代实用医学,2014,26(6):686-687.
[9]谢刚,原庆会,柯琦,等.免疫组化在老年胸腔积液细胞块病理诊断中的应用[J].四川医学,2015,36(7):935-937.
[10]罗丽花,张婉仪,刘惠娟,等.细胞块联合免疫组化在胸腔积液诊断中的应用[J].临床与实验病理学杂志,2015,31(8):904-907.
[11]王炳淑,刘友斌,卜平凤,等.细胞沉渣石蜡包埋、免疫组织化学染色病理检查对浆膜腔积液的定性诊断价值[J].山东医药,2015,55(28):98-99.
[12]张小伟,黄必飞,陈艳,等.细胞块技术在恶性浆膜腔积液组织来源及分子病理检测中的应用[J].浙江医学,2015,37(23):1891-1894.
[2]杨红敏,李振芬.细胞块切片免疫组化染色在胸腔积液病理诊断中的应用价值[J].中外医疗,2014,33(1):179.
[3]李中祥.细胞块切片免疫组化染色在胸腔积液病理诊断中的应用价值[J].河南医学研究,2015,24(4):88-89.
[4]吴家宁,杜芸,王珩,等.膜式细胞采集器在脱落细胞免疫组化染色中的临床应用[J].临床与实验病理学杂志,2014,30(6):694-696.
[5]姚岚.临床病理技术在胸腔积液细胞块中的应用[J].中国实用医刊,2016,43(6):101-102.
[6]黄其文,姜汉国.胸腔积液细胞块切片免疫组化染色技术鉴别诊断肺腺癌的临床研究[J].临床肺科杂志,2017,22(2):227-229.
[7]陈良娟.临床病理技术在胸腔积液中的应用研究[J].基层医学论坛,2017,21(20):2672-2673.
[8]沈湘萍,陈艳,张小伟.细胞块免疫组化在恶性小细胞肿瘤胸腔转移中的临床病理分析[J].现代实用医学,2014,26(6):686-687.
[9]谢刚,原庆会,柯琦,等.免疫组化在老年胸腔积液细胞块病理诊断中的应用[J].四川医学,2015,36(7):935-937.
[10]罗丽花,张婉仪,刘惠娟,等.细胞块联合免疫组化在胸腔积液诊断中的应用[J].临床与实验病理学杂志,2015,31(8):904-907.
[11]王炳淑,刘友斌,卜平凤,等.细胞沉渣石蜡包埋、免疫组织化学染色病理检查对浆膜腔积液的定性诊断价值[J].山东医药,2015,55(28):98-99.
[12]张小伟,黄必飞,陈艳,等.细胞块技术在恶性浆膜腔积液组织来源及分子病理检测中的应用[J].浙江医学,2015,37(23):1891-1894.