腹腔镜结肠癌根治术与开腹结肠癌根治术治疗结肠癌的效果比较
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摘要
目的比较腹腔镜结肠癌根治术与开腹结肠癌根治术治疗结肠癌的效果。方法选取2015年1月～2016年5月我院收治的100例结肠癌患者作为研究对象,采用随机数字表法将其分为实验组(n=50)和对照组(n=50)。对照组患者采用开腹结肠癌根治术治疗,实验组患者采用腹腔镜结肠癌根治术治疗。分析两组患者手术情况(手术时间、手术出血量、淋巴结清扫数)、近期疗效(胃肠功能恢复时间、住院天数、肠梗阻及切口感染发生率)以及远期疗效(疾病复发率、疾病转移发生率以及2年内生存率)的差异。结果两组患者的手术时间、淋巴结清扫数比较,差异无统计学意义(P>0.05);实验组患者的手术出血量明显少于对照组,差异有统计意义(P<0.05)。实验组患者的胃肠功能恢复时间、住院天数均明显短于对照组,肠梗阻、切口感染发生率均明显低于对照组,差异有统计学意义(P<0.05)。两组患者的疾病复发率、疾病转移发生率及2年内生存率比较,差异无统计学意义(P>0.05)。结论结肠癌患者接受腹腔镜结肠癌根治术以及开腹结肠癌根治术治疗,均具有一定的效果,其中腹腔镜结肠癌根治术的近期疗效更优。
Objective To compare the effect of laparoscopic radical resection of colon cancer and open radical resection of colon cancer in the treatment of colon cancer. Methods One hundred patients with colon cancer from January2015 to May 2016 were enrolled in the study. The patients were divided into experimental group(n=50) and control group(n=50) according to the random number table. In the control group, open radical resection of colon cancer was used, while in the experimental group, laparoscopic radical resection of colon cancer was adopted. The differences in surgical conditions(operation time, surgical bleeding volume, lymph node dissection), short-term efficacy(gastrointestinal recovery time, length of hospital stay, incidence rate of intestinal obstruction and wound infection) and long-term efficacy(disease recurrence rate, incidence rate disease metastasis and survival rate within 2 years) of patients in the two groups were analyzed. Results There were no significant differences in the operation time and lymph node dissection between the two groups(P>0.05). The surgical bleeding volume in the experimental group was significantly less than that in the control group, and the difference was statistically significant(P <0.05). The gastrointestinal recovery time and length of hospital stay in the experimental group were significantly shorter than those in the control group, the incidence rates of intestinal obstruction and wound infection were significantly lower than those in the control group,and the differences were statistically significant(P<0.05). There were no significant differences in incidence rate disease recurrence, disease metastasis rate and survival rate within 2 years between the two groups(P>0.05). Conclusion For patients with colon cancer, the application of laparoscopic radical resection of colon cancer and open radical resection of colon cancer obtain a certain effect, but the short-term efficacy of laparoscopic radical resection of colon cancer is better.
Objective To compare the effect of laparoscopic radical resection of colon cancer and open radical resection of colon cancer in the treatment of colon cancer. Methods One hundred patients with colon cancer from January2015 to May 2016 were enrolled in the study. The patients were divided into experimental group(n=50) and control group(n=50) according to the random number table. In the control group, open radical resection of colon cancer was used, while in the experimental group, laparoscopic radical resection of colon cancer was adopted. The differences in surgical conditions(operation time, surgical bleeding volume, lymph node dissection), short-term efficacy(gastrointestinal recovery time, length of hospital stay, incidence rate of intestinal obstruction and wound infection) and long-term efficacy(disease recurrence rate, incidence rate disease metastasis and survival rate within 2 years) of patients in the two groups were analyzed. Results There were no significant differences in the operation time and lymph node dissection between the two groups(P>0.05). The surgical bleeding volume in the experimental group was significantly less than that in the control group, and the difference was statistically significant(P <0.05). The gastrointestinal recovery time and length of hospital stay in the experimental group were significantly shorter than those in the control group, the incidence rates of intestinal obstruction and wound infection were significantly lower than those in the control group,and the differences were statistically significant(P<0.05). There were no significant differences in incidence rate disease recurrence, disease metastasis rate and survival rate within 2 years between the two groups(P>0.05). Conclusion For patients with colon cancer, the application of laparoscopic radical resection of colon cancer and open radical resection of colon cancer obtain a certain effect, but the short-term efficacy of laparoscopic radical resection of colon cancer is better.
引文
[1]洪心雅,张诗峰,丁志杰,等.免辅助切口腹腔镜下套管器经肛门取标本腹腔镜降结肠癌根治术[J].中华胃肠外科杂志,2015,18(5):501-503.
[2]周红飞.腹腔镜手术治疗对结肠癌患者性生活能力和胃肠道功能的影响[J].医学综述,2015,21(22):4183-4185,4188.
[3]吴岭,张建生,冯福梅,等.两种腹腔镜手术方案在乙状结肠癌患者中的疗效对比[J].中国内镜杂志,2018,24(5):85-89.
[4]刘洪.腹腔镜结肠癌切除联合完整结肠系膜切除在老年结肠癌手术中的应用[J].中国老年学杂志,2017,37(1):115-117.
[5]龚杰,黄雄,何山,等.经脐取标本并脐整形术在腹腔镜乙状结肠癌根治术中应用的对比研究[J].中国内镜杂志,2018,24(10):16-25.
[6]程勇,刘磊,王向阳,等.腹腔镜全结肠系膜切除术对结肠癌患者机体应激反应及腹腔脱落细胞的影响[J].中华实验外科杂志,2016,33(2):377-379.
[7]赵日升(摘译),汪挺(审校).单孔腹腔镜与传统腹腔镜手术治疗结肠癌的肿瘤学疗效比较[J].中华胃肠外科杂志,2015,18(8):787.
[8]彭吉绕.腹腔镜结肠癌根治术与传统术式可行性及安全性对比[J].中国现代普通外科进展,2015,18(2):145-146.
[9]曹金鹏,计勇,彭翔,等.腹腔镜完整结肠系膜切除术治疗横结肠癌的疗效评价[J].中华胃肠外科杂志,2017,20(5):545-549.
[10]张晓,李明,詹天成,等.手辅助腹腔镜与开腹乙状结肠癌根治术疗效对比的前瞻性对照研究[J].中华胃肠外科杂志,2015,18(5):442-445.
[11]莫波,马娟,郝志楠,等.结肠癌应用腹腔镜以及开腹手术治疗对机体免疫功能的影响比较[J].中国内镜杂志,2016,22(6):24-26.
[12]丁海涛,韩智君,曹杰,等.腹腔镜与传统开腹乙状结肠癌根治术临床疗效对比及安全性分析[J].现代中西医结合杂志,2016,25(35):3923-3926.
[13]李新峰,侯臣芳.腹腔镜结肠癌根治术与开腹结肠癌根治术的近、远期疗效对比[J].现代肿瘤医学,2017,25(4):584-587.
[14]吕海栋,刘国庆.腹腔镜、开腹手术治疗的右半结肠癌患者术后炎症状态及T细胞亚群分布比较[J].山东医药,2017,57(40):69-71.
[15]黄建国,刘乃青,丁元升,等.全结肠系膜切除术在腹腔镜与开腹右半结肠癌根治术中应用的对比研究[J].中国现代普通外科进展,2015,18(3):185-188.
[2]周红飞.腹腔镜手术治疗对结肠癌患者性生活能力和胃肠道功能的影响[J].医学综述,2015,21(22):4183-4185,4188.
[3]吴岭,张建生,冯福梅,等.两种腹腔镜手术方案在乙状结肠癌患者中的疗效对比[J].中国内镜杂志,2018,24(5):85-89.
[4]刘洪.腹腔镜结肠癌切除联合完整结肠系膜切除在老年结肠癌手术中的应用[J].中国老年学杂志,2017,37(1):115-117.
[5]龚杰,黄雄,何山,等.经脐取标本并脐整形术在腹腔镜乙状结肠癌根治术中应用的对比研究[J].中国内镜杂志,2018,24(10):16-25.
[6]程勇,刘磊,王向阳,等.腹腔镜全结肠系膜切除术对结肠癌患者机体应激反应及腹腔脱落细胞的影响[J].中华实验外科杂志,2016,33(2):377-379.
[7]赵日升(摘译),汪挺(审校).单孔腹腔镜与传统腹腔镜手术治疗结肠癌的肿瘤学疗效比较[J].中华胃肠外科杂志,2015,18(8):787.
[8]彭吉绕.腹腔镜结肠癌根治术与传统术式可行性及安全性对比[J].中国现代普通外科进展,2015,18(2):145-146.
[9]曹金鹏,计勇,彭翔,等.腹腔镜完整结肠系膜切除术治疗横结肠癌的疗效评价[J].中华胃肠外科杂志,2017,20(5):545-549.
[10]张晓,李明,詹天成,等.手辅助腹腔镜与开腹乙状结肠癌根治术疗效对比的前瞻性对照研究[J].中华胃肠外科杂志,2015,18(5):442-445.
[11]莫波,马娟,郝志楠,等.结肠癌应用腹腔镜以及开腹手术治疗对机体免疫功能的影响比较[J].中国内镜杂志,2016,22(6):24-26.
[12]丁海涛,韩智君,曹杰,等.腹腔镜与传统开腹乙状结肠癌根治术临床疗效对比及安全性分析[J].现代中西医结合杂志,2016,25(35):3923-3926.
[13]李新峰,侯臣芳.腹腔镜结肠癌根治术与开腹结肠癌根治术的近、远期疗效对比[J].现代肿瘤医学,2017,25(4):584-587.
[14]吕海栋,刘国庆.腹腔镜、开腹手术治疗的右半结肠癌患者术后炎症状态及T细胞亚群分布比较[J].山东医药,2017,57(40):69-71.
[15]黄建国,刘乃青,丁元升,等.全结肠系膜切除术在腹腔镜与开腹右半结肠癌根治术中应用的对比研究[J].中国现代普通外科进展,2015,18(3):185-188.
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