摘要
蛋白酪氨酸磷酸酶1B(PTP1B)是治疗II型糖尿病的潜在的重要靶点,与肥胖、肿瘤也具有密切关系。本文以PTP1B抑制剂专利文献为基础,对其专利申请态势、地区分布、活跃度、重点申请人等进行了统计分析。
Protein tyrosine phosphatase 1B(PTP1B)is a potential important target for the treatment of type 2 diabetes,and is closely related to obesity and tumors.Based on the patent literature of PTP1B inhibitors,this paper makes a statistical analysis of its patent application situation,regional distribution,activity,and key applicants.
引文
[1]杨猛,高天虹.蛋白酪氨酸磷酸酶1B(PTP1B)抑制剂的研究进展[J].河南化工,2015(32):11-15.
[2]袁仲,陈卓,李乾斌,胡高云.蛋白酪氨酸磷酸酶1B及其抑制剂的研究进展[J].中国药科大学学报,2018(49):1-9.
[3]张雪莲,郑海洲,郑智慧.PTP1B作为药物靶点的研究进展[J].国外医药抗生素分册,2017(38):173-178.