系统性红斑狼疮合并睡眠障碍现状及影响因素研究
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摘要
目的:研究与观察系统性红斑狼疮合并睡眠障碍现状及影响因素。方法:选取2017年2月至2018年11月期间四川省德阳市人民医院风湿免疫科诊治的系统性红斑狼疮患者136例为研究对象,将其睡眠障碍发生率进行统计,比较不同性别、年龄、文化程度、病程、疼痛程度、心理状态、疾病活动指数、药物应用量及收入情况者的睡眠障碍发生率,采用多因素Logistic回归分析上述因素与系统性红斑狼疮合并睡眠障碍的关系。结果:136例系统性红斑狼疮患者的睡眠障碍发生率为41. 18%(56/136),不同文化程度及收入情况者的睡眠障碍发生率比较,差异无统计学意义(P> 0. 05),不同性别、年龄、病程、疼痛程度、心理状态、疾病活动指数及药物应用量者的睡眠障碍发生率比较,差异有统计学意义(P <0. 05),多因素Logistic回归分析显示,性别、年龄、病程、疼痛程度、心理状态、疾病活动指数及药物应用量是系统性红斑狼疮合并睡眠障碍的影响因素(P <0. 05)。结论:系统性红斑狼疮合并睡眠障碍的发生率较高,且影响因素较多。
Objective: To study and observe the status of systemic lupus erythematosus complicated with sleep disorders and its influence factors. Methods: A Total of 136 patients with systemic lupus erythematosus in our hospital from February 2017 to November 2018 were chosen as the study object,and the sleep disorders rate of all the patients was analyzed,and the sleep disorders rates of patients with different gender,ages,education degree,disease course,pain degree,psychology state,disease activity index,dose of drug application and income situation were compared,and the relationship between those factors and systemic lupus erythematosus complicated with sleep disorders were analyzed with multivariate Logistic regression analysis. Results: The sleep disorders rate of136 patients with systemic lupus erythematosus was 41. 18%( 56/136),the sleep disorders rates of patients with different education degree and income situation were compared,the differences were not statistically significant( P > 0. 05),the sleep disorders rates of patients with different gender,ages,disease course,pain degree,psychology state,disease activity index and dose of drug application were compared,the differences were statistically significant( P < 0. 05),the multivariate Logistic regression analysis showed the gender,ages,disease course,pain degree,psychology state,disease activity index and dose of drug application were the influence factors of systemic lupus erythematosus complicated with sleep disorders( P < 0. 05). Conclusion: The sleep disorders rate of patients with systemic lupus erythematosus is high,and the influence factors are more.
Objective: To study and observe the status of systemic lupus erythematosus complicated with sleep disorders and its influence factors. Methods: A Total of 136 patients with systemic lupus erythematosus in our hospital from February 2017 to November 2018 were chosen as the study object,and the sleep disorders rate of all the patients was analyzed,and the sleep disorders rates of patients with different gender,ages,education degree,disease course,pain degree,psychology state,disease activity index,dose of drug application and income situation were compared,and the relationship between those factors and systemic lupus erythematosus complicated with sleep disorders were analyzed with multivariate Logistic regression analysis. Results: The sleep disorders rate of136 patients with systemic lupus erythematosus was 41. 18%( 56/136),the sleep disorders rates of patients with different education degree and income situation were compared,the differences were not statistically significant( P > 0. 05),the sleep disorders rates of patients with different gender,ages,disease course,pain degree,psychology state,disease activity index and dose of drug application were compared,the differences were statistically significant( P < 0. 05),the multivariate Logistic regression analysis showed the gender,ages,disease course,pain degree,psychology state,disease activity index and dose of drug application were the influence factors of systemic lupus erythematosus complicated with sleep disorders( P < 0. 05). Conclusion: The sleep disorders rate of patients with systemic lupus erythematosus is high,and the influence factors are more.
引文
[1]刘頔,左晓霞,曾芙蓉,等.系统性红斑狼疮患者睡眠障碍及相关因素研究[J].中华风湿病学杂志,2018,22(5):309-313.
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[4]徐维芳,陈柄泉,彭智勇,等.综合医院心血管内科门诊患者失眠症发生率及其影响因素[J].中国医师杂志,2018,20(1):96-99.
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[6]石磊,韩晓蕾,石蕊,等.类风湿关节炎患者睡眠质量与疾病活动度相关性分析[J].中华风湿病学杂志,2018,22(7):435-439.
[7]褚国琴,占开花,胡成琛住院老年人健康信念与睡眠质量的关系及心理弹性的中介作用[J].中国慢性病预防与控制,2018,26(9):696-699.
[8]Mark L Unruh,Brett Larive,Paul W Eggers,et al.The effect of frequent hemodialysis on self-reported sleep quality:Frequent Hemodialysis Network Trials[J].Nephrol Dial Transplant,2016,31(6):984-991.
[9]Marzena Olesińska,Agata Saletra.Quality of life in systemic lupus erythematosus and its measurement[J].Reumatologia,2018,56(1):45-54.
[10]周玲.心血管内科住院病人失眠相关因素分析及对策[J].中西医结合心血管病(连续型电子期刊),2018,6(2):19-20.
[11]曾芙蓉,徐倩云,刘頔,等.系统性红斑狼疮患者生活质量影响因素分析[J].临床内科杂志,2017,34(6):386-390.
[12]Tiffany J Braley,Ronald D Chervin.A practical approach to the diagnosis and management of sleep disorders in patients with multiple sclerosis[J].Ther Adv Neurol Disord,2015,8(6):294-310.
[13]刘新,谢彤,陈铭扬,等.湛江地区系统性红斑狼疮患者生活质量现状及影响因素分析[J].护理实践与研究,2017,14(8):1-4.
[14]王苏丽,吕良敬.系统性红斑狼疮患者的生活质量研究现状机遇与挑战并存[J].中华风湿病学杂志,2018,22(4):217-219.
[15]霍月红,宋志宙,席海英.系统性红斑狼疮生活质量和心理健康水平的研究[J].心理医生,2016,22(30):272-273.
[2]张文皓,吴振彪,王晶,等.396例系统性红斑狼疮患者心理弹性及影响因素分析[J].护理学报,2018,25(7):36-41.
[3]龚丽,程书华,高冠民,等.系统性红斑狼疮患者睡眠质量及其影响因素分析[J].中华现代护理杂志,2018,24(4):393-397.
[4]徐维芳,陈柄泉,彭智勇,等.综合医院心血管内科门诊患者失眠症发生率及其影响因素[J].中国医师杂志,2018,20(1):96-99.
[5]魏晨.风湿内科患者睡眠情况的影响因素及干预研究[J].当代护士(中旬刊),2018,26(1):23-25.
[6]石磊,韩晓蕾,石蕊,等.类风湿关节炎患者睡眠质量与疾病活动度相关性分析[J].中华风湿病学杂志,2018,22(7):435-439.
[7]褚国琴,占开花,胡成琛住院老年人健康信念与睡眠质量的关系及心理弹性的中介作用[J].中国慢性病预防与控制,2018,26(9):696-699.
[8]Mark L Unruh,Brett Larive,Paul W Eggers,et al.The effect of frequent hemodialysis on self-reported sleep quality:Frequent Hemodialysis Network Trials[J].Nephrol Dial Transplant,2016,31(6):984-991.
[9]Marzena Olesińska,Agata Saletra.Quality of life in systemic lupus erythematosus and its measurement[J].Reumatologia,2018,56(1):45-54.
[10]周玲.心血管内科住院病人失眠相关因素分析及对策[J].中西医结合心血管病(连续型电子期刊),2018,6(2):19-20.
[11]曾芙蓉,徐倩云,刘頔,等.系统性红斑狼疮患者生活质量影响因素分析[J].临床内科杂志,2017,34(6):386-390.
[12]Tiffany J Braley,Ronald D Chervin.A practical approach to the diagnosis and management of sleep disorders in patients with multiple sclerosis[J].Ther Adv Neurol Disord,2015,8(6):294-310.
[13]刘新,谢彤,陈铭扬,等.湛江地区系统性红斑狼疮患者生活质量现状及影响因素分析[J].护理实践与研究,2017,14(8):1-4.
[14]王苏丽,吕良敬.系统性红斑狼疮患者的生活质量研究现状机遇与挑战并存[J].中华风湿病学杂志,2018,22(4):217-219.
[15]霍月红,宋志宙,席海英.系统性红斑狼疮生活质量和心理健康水平的研究[J].心理医生,2016,22(30):272-273.