江西省2011-2017年人间布鲁氏菌病疫情分析
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摘要
目的掌握江西省2011-2017年人间布鲁氏菌病疫情特征,为今后的防控工作提供参考依据。方法结合省内监测资料,对江西省2011-2017年在传染病报告信息管理系统中报告的布病病例进行分析。结果 2011-2017年江西省共报告布病239例,年均发病率为0. 08/10万。病例和聚集性疫情集中在南昌市地区(48例/4起)。地市分布由2011年的1个地级市至2016年全覆盖,涉及县(区)数由2011年的1个增长至2017年的68个,扩增趋势明显(x~2趋势=94. 31,P <0. 001)。男女性别比为3. 12∶1(181∶58)。年龄集中在40～65岁年龄组。职业分布以农牧民为主,占59. 83%(143/239)。5～9月为发病高峰(5～6月大高峰和9月小高峰)。2012-2017年共采集血清样本7 160份,阳性率1. 33%(95/7 160)。2013-2017年从193例病例血液中分离出布病菌株62株,羊Ⅰ4株,羊Ⅲ54株,猪Ⅰ4株。结论江西省人间布病疫情呈上升势态,流行范围在不断扩大。有关部门加强监管力度、扩充监测内容可能为今后的布病防控重点。
Objective To investigate the epidemic characteristics of human brucellosis in Jiangxi province from 2011 to 2017,thereby providing reference for future prevention and control work. Methods We analyzed the case information reported in the National Notifiable Infectious Diseases Reporting Information System of Jiangxi Province during 2011-2017 by combining with the monitoring data. Results A total of 239 cases were recorded over these six years,with an average incidence rate of 0. 08/100000. Most cases and agglomerations were concentrated in the Nanchang area( 48 cases/4 cases),with the case distribution ranging from 1 in 2011 to all in 2016,and the number of counties( districts) involved had increased from 1 in 2011 to 68 in 2017,which increased rapidly year by year( x~2= 94. 31,P <0. 001). The gender ratio was 3. 12 ∶ 1( 181 ∶ 58). Most cases were concentrated in the 40-65 age group,while farmers and herdsmen were high-risk population,accounting for 59. 83 %( 143/239). The incidence of brucellosis peaked from May to September( May peak and September peak). In 2012-2017,7 160 blood samples were collected from risk population,with 95 being positive for Brucella( 1. 33%). From 2013 to 2017,62 strains of the Brucella,4 were Brucella melitensis type1,54 were Brucella melitensis type3 and 4 were Brucella suis were isolated from 193 cases. Conclusions The human brucellosis was aggravated in Jiangxi province,with the expansion of regional scope. Therefore,more efforts should be focused on regulation to prevent and control brucellosis better.
Objective To investigate the epidemic characteristics of human brucellosis in Jiangxi province from 2011 to 2017,thereby providing reference for future prevention and control work. Methods We analyzed the case information reported in the National Notifiable Infectious Diseases Reporting Information System of Jiangxi Province during 2011-2017 by combining with the monitoring data. Results A total of 239 cases were recorded over these six years,with an average incidence rate of 0. 08/100000. Most cases and agglomerations were concentrated in the Nanchang area( 48 cases/4 cases),with the case distribution ranging from 1 in 2011 to all in 2016,and the number of counties( districts) involved had increased from 1 in 2011 to 68 in 2017,which increased rapidly year by year( x~2= 94. 31,P <0. 001). The gender ratio was 3. 12 ∶ 1( 181 ∶ 58). Most cases were concentrated in the 40-65 age group,while farmers and herdsmen were high-risk population,accounting for 59. 83 %( 143/239). The incidence of brucellosis peaked from May to September( May peak and September peak). In 2012-2017,7 160 blood samples were collected from risk population,with 95 being positive for Brucella( 1. 33%). From 2013 to 2017,62 strains of the Brucella,4 were Brucella melitensis type1,54 were Brucella melitensis type3 and 4 were Brucella suis were isolated from 193 cases. Conclusions The human brucellosis was aggravated in Jiangxi province,with the expansion of regional scope. Therefore,more efforts should be focused on regulation to prevent and control brucellosis better.
引文
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[9]秦秋翠,李直健,陈雪琼,等.广西贺州市一起因食用未煮熟羊奶引起的布鲁氏菌病暴发疫情调查[J].疾病监测,2017,32(8):634-637. DOI:10. 3784/j. issn. 1003-9961. 2017. 08. 006.Qin QC,Li ZJ,Chen XQ,et al. Epidemiological investigation of an outbreak of brucellosis caused by drinking of unpasteurized ewe's milk in Hezhou of Guangxi[J]. Dis Surveill,2017,32(8):634-637. DOI:10. 3784/j. issn. 1003-9961. 2017. 08. 006.
[10]柯春荣,李文娟,马顺高,等.一起通过性传播的布病疫情调查[J].疾病监测与控制,2015,9(3):170-171.Ke CR,Li WJ,Ma SG,et al. An investigation into the prevalence of sexually transmitted brucellosiss[J]. J Diseases Monitor&Control,2015,9(3):170-171.
[11]陈宝宝,范锁平,安翠红,等.陕西省2005-2015年布鲁杆菌病疫情分析[J].中华疾病控制杂志,2017,21(1):99-101.DOI:10. 16462/j. cnki. zhjbkz. 2017. 01. 023.Chen BB,Fan SP,An CH,et al. Analysis of brucellosis epidemic from 2005 to 2015 in Shaanxi[J]. Chin J Dis Control Prev,2017,21(1):99-101. DOI:10. 16462/j. cnki. zhjbkz. 2017. 01.023.
[12]张新岩,李树博,范凯,等. 2001-2015年锦州市布鲁氏菌病疫情流行病学分析[J].中国人兽共患病学报,2018,34(1):35-38. DOI:10. 3969/j. issn. 1002-2694. 2018. 00. 003.Zhang XY,Li SB,Fan K,et al. Epidemiological analysis of brucellosis in Jinzhou city,China,2001-2015[J]. Chin J Zoonoses,2018,34(1):35-38. DOI:10. 3969/j. issn. 1002-2694. 2018. 00.003.
[13]王舒,殷文武,张义,等.陕西省绥德县基层医务人员布鲁菌病诊断报告能力调查[J].中华地方病学杂志,2017,36(10):768-771. DOI:10. 3760/cma. j. issn. 2095-4255. 2017. 10. 016.Wang S,Yin WW,Zhang Y,et al. An investigation on the ability in diagnosing and reporting brucellosis of primary medical personnel in Suide county of Shaanxi Province[J]. Chin J Endemiol,2017,36(10):768-771. DOI:10. 3760/cma. j. issn. 2095-4255.2017. 10. 016.
[14]胡小琦,彭焕文.四川省达州市非牧区布鲁菌病防控措施探讨[J].中华地方病学杂志,2017,36(6):454. DOI:10. 3760/cma. j. issn. 2095-4255. 2017. 06. 016.Hu XQ,Peng HW. Discussion on prevention and control measures of brucellosis in non-pastoral areas of dazhou city,sichuan province[J]. Chin J Endemiol,2017,36(6):454. DOI:10. 3760/cma. j. issn. 2095-4255. 2017. 06. 016.
[2]徐建民,宗俊,杨梦,等.江西省首次从当地人群中分离出布鲁氏菌及其流行病学分析[J].中华流行病学杂志,2014,35(5):616. DOI:10. 3760/cma. j. issn. 0254-6450. 2014. 05. 034.Xu JM,Zong J,Yang M,et al. Isolation of Brucella from human specimen and epidemiological analysis in Jiangxi Province[J].Chin J Epidemiol,2014,35(5):616. DOI:10. 3760/cma. j. issn.0254-6450. 2014. 05. 034.
[3]施玉静,赖圣杰,陈秋兰,等.我国南北方2015-2016年人间布鲁氏菌病流行特征分析[J].中华流行病学杂志,2017,38(4):435-440. DOI:10. 3760/cma. j. issn. 0254-6450. 2017. 04.005.Shi YJ,Lai SJ,Chen QL,et al. Analysis on the epidemiological features of human brucellosis in northern and southern areas of China,2015-2016[J]. Chin J Epidemiol,2017,38(4):435-440. DOI:10. 3760/cma. j. issn. 0254-6450. 2017. 04. 005.
[4]中华人民共和国卫生部. WS269-2007布鲁氏菌病诊断标准[S].北京:中国标准出版社,2007.Ministry of Health of People's Republic of China. WS269-2007 brucellosis diagnostic criteria[S]. Beijing:China Standard Press,2007.
[5]李旦,邢学森,刘力,等. 2010-2016年湖北省人间布鲁氏菌病流行病学特征分析[J].疾病监测,2018,33(3):203-207.DOI:10. 3784/j. issn. 1003-9961. 2018. 03. 008.Li D,Xing XS,Liu L,et al. Epidemiological characteristics of human brucellosis in Hubei,2010-2016[J]. Dis Surveill,2018,33(3):203-207. DOI:10. 3784/j. issn. 1003-9961. 2018. 03.008.
[6]伍忠辉,高立冬,胡世雄,等. 2010-2014年湖南省人间布鲁氏菌病网络直报系统监测数据分析[J].实用预防医学,2017,24(9):1117-1119. DOI:10. 3969/j. issn. 1006-3110.2017. 09. 026.Wu ZH,Gao LD,Hu SX,et al. Surveillance data of human brucellosis cases from the network direct reporting system in Hunan Province,2010-2014[J]. Pract Prev Med,2017,24(9):1117-1119. DOI:10. 3969/j. issn. 1006-3110. 2017. 09. 026.
[7]施旭光,孙继民,凌锋. 2015年浙江省人间布鲁氏菌病监测结果分析[J].疾病监测,2017,32(3):203-205. DOI:10. 3784/j. issn. 1003-9961. 2017. 03. 009.Shi XG,Sun JM,Ling F. Surveillance for brucellosis in Zhejiang Province,2015[J]. Dis Surveill,2017,32(3):203-205. DOI:10. 3784/j. issn. 1003-9961. 2017. 03. 009.
[8]祝寒松,谢忠杭,许志斌,等.福建省2011-2015年人间布鲁氏菌病疫情分析[J].中华疾病控制杂志,2017,21(8):818-821. DOI:10. 16462/j. cnki. zhjbkz. 2017. 08. 016.Zhu HS,Xie ZH,Xu ZB,et al. Epidemic situation analysis of human brucellosis in Fujian Province,2011-2015[J]. Chin J Dis Control Prev,2017,21(8):818-821. DOI:10. 16462/j. cnki.zhjbkz. 2017. 08. 016.
[9]秦秋翠,李直健,陈雪琼,等.广西贺州市一起因食用未煮熟羊奶引起的布鲁氏菌病暴发疫情调查[J].疾病监测,2017,32(8):634-637. DOI:10. 3784/j. issn. 1003-9961. 2017. 08. 006.Qin QC,Li ZJ,Chen XQ,et al. Epidemiological investigation of an outbreak of brucellosis caused by drinking of unpasteurized ewe's milk in Hezhou of Guangxi[J]. Dis Surveill,2017,32(8):634-637. DOI:10. 3784/j. issn. 1003-9961. 2017. 08. 006.
[10]柯春荣,李文娟,马顺高,等.一起通过性传播的布病疫情调查[J].疾病监测与控制,2015,9(3):170-171.Ke CR,Li WJ,Ma SG,et al. An investigation into the prevalence of sexually transmitted brucellosiss[J]. J Diseases Monitor&Control,2015,9(3):170-171.
[11]陈宝宝,范锁平,安翠红,等.陕西省2005-2015年布鲁杆菌病疫情分析[J].中华疾病控制杂志,2017,21(1):99-101.DOI:10. 16462/j. cnki. zhjbkz. 2017. 01. 023.Chen BB,Fan SP,An CH,et al. Analysis of brucellosis epidemic from 2005 to 2015 in Shaanxi[J]. Chin J Dis Control Prev,2017,21(1):99-101. DOI:10. 16462/j. cnki. zhjbkz. 2017. 01.023.
[12]张新岩,李树博,范凯,等. 2001-2015年锦州市布鲁氏菌病疫情流行病学分析[J].中国人兽共患病学报,2018,34(1):35-38. DOI:10. 3969/j. issn. 1002-2694. 2018. 00. 003.Zhang XY,Li SB,Fan K,et al. Epidemiological analysis of brucellosis in Jinzhou city,China,2001-2015[J]. Chin J Zoonoses,2018,34(1):35-38. DOI:10. 3969/j. issn. 1002-2694. 2018. 00.003.
[13]王舒,殷文武,张义,等.陕西省绥德县基层医务人员布鲁菌病诊断报告能力调查[J].中华地方病学杂志,2017,36(10):768-771. DOI:10. 3760/cma. j. issn. 2095-4255. 2017. 10. 016.Wang S,Yin WW,Zhang Y,et al. An investigation on the ability in diagnosing and reporting brucellosis of primary medical personnel in Suide county of Shaanxi Province[J]. Chin J Endemiol,2017,36(10):768-771. DOI:10. 3760/cma. j. issn. 2095-4255.2017. 10. 016.
[14]胡小琦,彭焕文.四川省达州市非牧区布鲁菌病防控措施探讨[J].中华地方病学杂志,2017,36(6):454. DOI:10. 3760/cma. j. issn. 2095-4255. 2017. 06. 016.Hu XQ,Peng HW. Discussion on prevention and control measures of brucellosis in non-pastoral areas of dazhou city,sichuan province[J]. Chin J Endemiol,2017,36(6):454. DOI:10. 3760/cma. j. issn. 2095-4255. 2017. 06. 016.