胺碘酮与利多卡因治疗急性心肌梗死后室性心律失常的疗效比较研究
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摘要
目的比较胺碘酮与利多卡因治疗急性心肌梗死后室性心律失常的临床疗效。方法回顾性分析阿克苏市人民医院2012年3月—2018年5月收治的急性心肌梗死后室性心律失常患者58例,根据治疗方案不同分为A组和B组,各29例。A组患者采用利多卡因治疗,B组患者采用胺碘酮治疗。比较两组患者临床疗效及治疗后舒张压(DBP)、收缩压(SBP),并观察两组患者不良反应发生情况。结果 B组患者临床疗效优于A组(P<0.05)。B组患者DBP、SBP及不良反应发生率低于A组(P<0.05)。结论胺碘酮治疗急性心肌梗死后室性心律失常的临床疗效优于利多卡因,其可更有效改善患者的临床症状及体征,且降压效果明显,安全性更高。
Objective To compare the clinical effect of amiodarone and lidocaine in treating ventricular arrhythmias after acute myocardial infarction.Methods A total of 58 cases of patients with ventricular arrhythmias after acute myocardial infarction were selected from March 2012 to May 2018 in Aksu People's Hospital,which were divided into A group and B group according to different methods,29 cases in each group.The A group was treated with lidocaine,B group was treated with amiodarone.The clinical effect and DBP,SBP were compared between the two groups,and the incidence of adverse reactions were observed.Results The clinical effect of B group was better than A group(P<0.05).The B group of DBP,SBP and incidence rate of adverse reactions were lower than A group(P<0.05).Conclusion Amiodarone has a better clinical effect for ventricular arrhythmias after acute myocardial infarction than lidocaine,it can effectively improve the clinical symptoms and signs of patients,and with high safety.
Objective To compare the clinical effect of amiodarone and lidocaine in treating ventricular arrhythmias after acute myocardial infarction.Methods A total of 58 cases of patients with ventricular arrhythmias after acute myocardial infarction were selected from March 2012 to May 2018 in Aksu People's Hospital,which were divided into A group and B group according to different methods,29 cases in each group.The A group was treated with lidocaine,B group was treated with amiodarone.The clinical effect and DBP,SBP were compared between the two groups,and the incidence of adverse reactions were observed.Results The clinical effect of B group was better than A group(P<0.05).The B group of DBP,SBP and incidence rate of adverse reactions were lower than A group(P<0.05).Conclusion Amiodarone has a better clinical effect for ventricular arrhythmias after acute myocardial infarction than lidocaine,it can effectively improve the clinical symptoms and signs of patients,and with high safety.
引文
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[2]吴春涛,马士新.重组人脑利钠肽对急性心肌梗死经皮冠状动脉介入治疗术后心力衰竭患者心肌酶、梗死面积的影响[J].中国介入心脏病学杂志,2016,24(7):394-397.
[3]余波,艾芬,杨飞燕.瑞舒伐他汀对急性心肌梗死PCI术后患者血清cTnI、CK-MB、Myo及血小板活化功能、炎性因子水平的影响[J].海南医学院学报,2016,22(19):2269-2272.
[4]母雪飞,赵昕,任丽丽,等.重组人脑利钠肽对急性心肌梗死经皮冠状动脉介入治疗术后并发急性左心衰竭患者的临床观察[J].中国介入心脏病学杂志,2016,24(1):32-36.
[5]关绍义,王晓燕,李晶,等.老年急性心肌梗死患者急诊经皮冠状动脉介入治疗围术期应用比伐芦定的疗效与安全性:BRIGHT研究预设亚组分析[J].中国介入心脏病学杂志,2016,24(8):421-426.
[6]梁滨,黄榕翀,康美丽,等.心电图以ST段抬高为特征的TakoSTubo心肌病与急性前壁ST段抬高型心肌梗死临床特征比较[J].中国循环杂志,2015,30(6):534-539.
[7]杜永波,成霄汉,薛巧云,等.院前无创机械通气辅助药物治疗急性心肌梗死并左心衰竭对患者血清NT-proBNP、CK-MB、TnI水平的影响[J].临床合理用药杂志,2015,8(34):64-65.
[8]宁小方,姬富才.急性心肌梗死合并心源性休克病人行主动脉内球囊反搏术联合经皮冠状动脉介入术的临床疗效分析[J].安徽医药,2017,21(8):1442-1444.
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