血清促甲状腺激素等指标在甲状腺结节影像、临床诊断中的参考价值

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英文篇名：The Reference Value of Serum Thyroid Stimulating Hormone and Other Indicators in the Imaging and Clinical Diagnosis of Thyroid Nodules 作者：王学强 ; 吴凯 ; 忻莹 英文作者：WANG Xueqiang;WU Kai;XIN Ying;Yiwu Hospital of Traditional Chinese Medicine;Zhejiang Provincial People's Hospital; 关键词：甲状腺肿瘤 ; 促甲状腺素 ; 甲状腺结节 ; 甲状腺影像报告和数据系统 英文关键词：thyroidneoplasms;;Thyrotropin;;Thyroid nodule;;TI-RADS 中文刊名：ZYJT 英文刊名：Zhejiang Medical Education 机构：义乌市中医医院;浙江省人民医院; 出版日期：2019-06-15 出版单位：浙江医学教育 年：2019 期：v.18;No.82 基金：浙江省基础公益研究计划(编号:LGC19H160001)@ 语种：中文; 页：ZYJT201903019 页数：4 CN：03 ISSN：33-1297/R 分类号：60-63

摘要

目的:研究血清促甲状腺激素(TSH)联合甲状腺影像报告和数据系统(TI-RADS)在3、4a、4b、4c、5类结节良恶性鉴别中的应用。方法:回顾性分析246例(恶性组72例,良性组174例)符合入组条件行甲状腺手术的甲状腺疾病患者,分析甲状腺影像报告和数据系统(TI-RADS)3、4a、4b、4c、5类结节中甲状腺癌所占比例,比较2组术前TSH水平及所有入组患者不同TSH水平组间甲状腺癌患病比例。结果:4a、4b类结节恶性组TSH表达水平显著高于良性组(P<0.05)。恶性组术前TSH水平显著高于良性组(P<0.05);不同TSH水平组甲状腺癌比例差异有统计学意义(P<0.05)。结论:TSH联合TI-RADS分类有助于甲状腺结节良恶性的鉴别。
        [Objective] To investigate the application of serum thyroid stimulating hormone(TSH) combined with thyroid imaging report and data system(TI-RADS) in the differentiation of benign and malignant nodules of 3, 4 a, 4 b, 4 c and 5 types. [Method] A total of 246 eligible patients with thyroid nodules undergoing thyroidectomy were enrolled, including 72 patients with thyroid carcinoma(Malignant group)and 174 patients with benign thyroid nodules(BTN group). Their clinical data were retrospectively reviewed. The proportion of thyroid carcinoma in thyroid imaging report and data system(TI-RADS) 3,4 a,4 b,4 c and 5 nodules were analyzed. The serum levels of TSH in two groups and the proportion of thyroid carcinoma in different serum TSH level groups in all patients were compared respectively. [Result] The serum levels of TSH in malignant group of 4 a and 4 b nodules was significantly higher than those in BTN group(P<0.05). The serum levels of TSH were higher in Malignant group than those in BTN group(P<0.05). There were statistical differences in thyroid carcinoma rates between groups with different TSH levels(P<0.05). [Conclusion] TSH level combined with TI-RADS classification is helpful for the identification of benign and malignant thyroid nodules.

引文

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