麦冬药性与功用考证
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摘要
通过查阅关于麦冬的古典古籍文献,在其功用基础上以年代为序,对麦冬的药性、方剂功用、临床应用进行考证做以总结,再结合相关文献资料对麦冬现代药理作用做以归类并进行初步探讨,以期为麦冬的临床合理用药提供科学依据。
By consulting on the classical ancient books about Maidong(Radix Ophiopogon Japonicus), in time axis, on the basis of its function, this paper makes a summary of the medicinal properties, the function of prescription and the clinical application of Maidong(Radix Ophiopogon Japonicus). Combined with the modern literature and data, the modern pharmacological action of it was classified and discussed, so as to provide scientific basis for cinical application for the future.
By consulting on the classical ancient books about Maidong(Radix Ophiopogon Japonicus), in time axis, on the basis of its function, this paper makes a summary of the medicinal properties, the function of prescription and the clinical application of Maidong(Radix Ophiopogon Japonicus). Combined with the modern literature and data, the modern pharmacological action of it was classified and discussed, so as to provide scientific basis for cinical application for the future.
引文
[1]吴普.神农本草经[M].北京:人民卫生出版社,1963.
[2]陈嘉谟.本草蒙筌[M].王淑民,陈湘萍,周超凡,点校.北京:人民卫生出版社,1990.
[3]陶弘景.名医别录[M].尚志军,辑校.北京:中国中医药出版社,2003.
[4]孙思邈.备急千金要方[M].焦振廉,校注.北京:中国医药科技出版社,2013:144.
[5]钱乙小儿药证直诀[M].郭君双,整理.北京:人民卫生出版社,2006.
[6]袁春丽,孙立,袁胜涛,等.麦冬有效成分的药理活性及作用机制研究进展[J].中国新药杂志,2013(22):2496-2502.
[7]WANG S,ZHANG Z,LIN X,et al.A polysaccharide,MDG-1,induces S1P1 and bFGF expression and augments survival andangiogenesis in the ischemic heart[J].Glycobiology,2010,20(4):473-484.
[8]李霞.麦冬多糖-1对心肌缺血再灌注大鼠内皮祖细胞与缺血修饰白蛋白变化的影响[J].中国老年学杂志,2015,35(19):5449-5450.
[9]周跃华,徐得生,冯怡,等.麦冬提取物对小鼠心肌营养血流量的影响[J].中国实验方剂学杂志,2003,9(1):22-24.
[10]高广猷,宋晓亮,叶丽红.山麦冬总氨基酸对大鼠实验性心肌缺血的保护作用[J].中国药理学通报,1993,9(4):281-283.
[11]徐德生,冯怡,周跃华,等.麦冬多糖中抗急性心肌缺血活性部位研究[J].中成药,2004,26(10):832-837.
[12]ZHENG Q,FENG Y,XU D S,et al.Influence of sulfation on anti-myocardial ischemic activity of Ophiopogon japonicus poly-saccharide[J].J AsianNat Prd Res,2009,11(4):306-321.
[13]刘琳.生脉散正交试验抗心律失常作用研究[J].黑龙江医药,2008,21(6)15-17.
[14]ZHAORP,SUN L,LIN S S,et al.The saponin monomer of dwarf lilyturf tuber,DT-13,inhibits angiogenesis under hypoxia and normoxia via multi-targeting activity[J].Oncol Rep,2013,29(4):1379-1386.
[15]余伯阳.从麦冬入手,探讨中药材现代系统研究的思路与方法[J].中国天然药物,2007,5(1):10-14.
[16]李琼.短葶山麦冬抗肿瘤有效部位与作用机制研究[D].泉州:华侨大学,2016.
[17]白雪.湖北麦冬对STZ诱导2型糖尿病小鼠的治疗作用及其作用机理的研究[D].武汉:华中科技大学,2009.
[18]苟兴能,张克英,勾宗蓉,等.川麦冬多糖对四氧嘧啶糖尿病小鼠的降血糖作用的实验研究[J].食品工业科技,2012,33(13):359-360,391.
[19]王源,王硕,王令仪,等.麦冬多糖MDG-1对糖尿病小鼠模型的降糖作用[J].上海中医药大学学报,2011,25(4):66-70.
[20]李晶,苏薇薇,王永刚,等.麦冬多糖提取工艺的优选及降血糖作用研究[J].中医药导报,2017,23(24):52-54.
[21]武晓群.沙参麦冬汤和麦冬皂苷D延缓衰老的作用及机制研究[D].南京:南京中医药大学,2012.
[22]刘杰书.麦冬注射液抗衰老作用机制研究[J].中国药房,2006(23):1774-1775.
[2]陈嘉谟.本草蒙筌[M].王淑民,陈湘萍,周超凡,点校.北京:人民卫生出版社,1990.
[3]陶弘景.名医别录[M].尚志军,辑校.北京:中国中医药出版社,2003.
[4]孙思邈.备急千金要方[M].焦振廉,校注.北京:中国医药科技出版社,2013:144.
[5]钱乙小儿药证直诀[M].郭君双,整理.北京:人民卫生出版社,2006.
[6]袁春丽,孙立,袁胜涛,等.麦冬有效成分的药理活性及作用机制研究进展[J].中国新药杂志,2013(22):2496-2502.
[7]WANG S,ZHANG Z,LIN X,et al.A polysaccharide,MDG-1,induces S1P1 and bFGF expression and augments survival andangiogenesis in the ischemic heart[J].Glycobiology,2010,20(4):473-484.
[8]李霞.麦冬多糖-1对心肌缺血再灌注大鼠内皮祖细胞与缺血修饰白蛋白变化的影响[J].中国老年学杂志,2015,35(19):5449-5450.
[9]周跃华,徐得生,冯怡,等.麦冬提取物对小鼠心肌营养血流量的影响[J].中国实验方剂学杂志,2003,9(1):22-24.
[10]高广猷,宋晓亮,叶丽红.山麦冬总氨基酸对大鼠实验性心肌缺血的保护作用[J].中国药理学通报,1993,9(4):281-283.
[11]徐德生,冯怡,周跃华,等.麦冬多糖中抗急性心肌缺血活性部位研究[J].中成药,2004,26(10):832-837.
[12]ZHENG Q,FENG Y,XU D S,et al.Influence of sulfation on anti-myocardial ischemic activity of Ophiopogon japonicus poly-saccharide[J].J AsianNat Prd Res,2009,11(4):306-321.
[13]刘琳.生脉散正交试验抗心律失常作用研究[J].黑龙江医药,2008,21(6)15-17.
[14]ZHAORP,SUN L,LIN S S,et al.The saponin monomer of dwarf lilyturf tuber,DT-13,inhibits angiogenesis under hypoxia and normoxia via multi-targeting activity[J].Oncol Rep,2013,29(4):1379-1386.
[15]余伯阳.从麦冬入手,探讨中药材现代系统研究的思路与方法[J].中国天然药物,2007,5(1):10-14.
[16]李琼.短葶山麦冬抗肿瘤有效部位与作用机制研究[D].泉州:华侨大学,2016.
[17]白雪.湖北麦冬对STZ诱导2型糖尿病小鼠的治疗作用及其作用机理的研究[D].武汉:华中科技大学,2009.
[18]苟兴能,张克英,勾宗蓉,等.川麦冬多糖对四氧嘧啶糖尿病小鼠的降血糖作用的实验研究[J].食品工业科技,2012,33(13):359-360,391.
[19]王源,王硕,王令仪,等.麦冬多糖MDG-1对糖尿病小鼠模型的降糖作用[J].上海中医药大学学报,2011,25(4):66-70.
[20]李晶,苏薇薇,王永刚,等.麦冬多糖提取工艺的优选及降血糖作用研究[J].中医药导报,2017,23(24):52-54.
[21]武晓群.沙参麦冬汤和麦冬皂苷D延缓衰老的作用及机制研究[D].南京:南京中医药大学,2012.
[22]刘杰书.麦冬注射液抗衰老作用机制研究[J].中国药房,2006(23):1774-1775.