探讨替罗非班在冠心病介入治疗中预防慢血流的效果
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摘要
目的探究冠心病介入治疗中应用替罗非班预防慢血流的效果。方法随机选取2016年1月～2017年2月在本院进行冠心病介入的患者76例作为研究对象,按照手术日期先后顺序将其分为研究组和对照组,各38例,对照组使用硝酸甘油,研究组使用替罗非班,将两种方案治疗效果分析对比。结果在TIMI分级和治疗后LVEF水平上,研究组全部优于对照组,差异有统计学意义(P<0.05);两组患者在术后ST段回落以及不良心血管事件发生率差以上,差异无统计学意义(P>0.05)。结论冠心病介入治疗中应用替罗非班预防慢血流效果较好,可显著提升心肌灌注功能。
Objective To investigate the clinical effect of tiro?ban in the prevention of slow blood ? ow in interventional therapy for coronary heart disease.Methods A total of 76 patients who underwent coronary heart disease intervention in our hospital from January 2016 to February 2017 were randomly selected and divided into study group(n=38) and control group(n=38) according to the date of operation. The control group used nitroglycerin,and the study group used tirofiban to compare the therapeutic effects of the two regimens.Results In the TIMI grading and post-treatment LVEF levels, the study group was superior to the control group, and the difference was statistically signi?cant(P<0.05). The postoperative ST segment regression and adverse cardiovascular events were worse than the two groups. Not statistically signi?cant(P>0.05).Conclusion The use of tiro?ban in the treatment of coronary heart disease is better in preventing slow blood ? ow and can signi?cantly improve myocardial perfusion.
Objective To investigate the clinical effect of tiro?ban in the prevention of slow blood ? ow in interventional therapy for coronary heart disease.Methods A total of 76 patients who underwent coronary heart disease intervention in our hospital from January 2016 to February 2017 were randomly selected and divided into study group(n=38) and control group(n=38) according to the date of operation. The control group used nitroglycerin,and the study group used tirofiban to compare the therapeutic effects of the two regimens.Results In the TIMI grading and post-treatment LVEF levels, the study group was superior to the control group, and the difference was statistically signi?cant(P<0.05). The postoperative ST segment regression and adverse cardiovascular events were worse than the two groups. Not statistically signi?cant(P>0.05).Conclusion The use of tiro?ban in the treatment of coronary heart disease is better in preventing slow blood ? ow and can signi?cantly improve myocardial perfusion.
引文
[1]顾霞,夏文胜,陆红进.冠脉内注射替罗非班对PPCI中慢血流的影响分析[J].贵州医药,2017,41(7):705-707.
[2]程昭栋,杨体霞,周利民,等.血栓抽吸与替罗非班的不同应用顺序对急诊经皮冠状动脉介入术后慢血流或无复流的影响[J].中国临床保健杂志,2016,19(1):63-65.
[3]张鸿雁,李楠.替罗非班在老年急性非ST段抬高型心肌梗死患者择期介入治疗中的临床意义[J].中华老年心脑血管病杂志2016,18(2):196-197.
[4]黄宇辉,许春平,曾波.急性心肌梗死介入治疗中血栓抽吸联合替罗非班的疗效分析[J].血栓与止血学,2017,23(4):577-579.
[5]张杰,宋红星,朱新锋.冠状动脉内替罗非班对急诊介入术中慢血流的影响[J].中国医药指南,2016,14(23):18-19.
[6]黄宇彬,黄余健,陈金灶.冠脉内注射替罗非班和硝普钠对PCI术中无复流的疗效[J].心血管康复医学杂志,2016,25(3):280-283.
[2]程昭栋,杨体霞,周利民,等.血栓抽吸与替罗非班的不同应用顺序对急诊经皮冠状动脉介入术后慢血流或无复流的影响[J].中国临床保健杂志,2016,19(1):63-65.
[3]张鸿雁,李楠.替罗非班在老年急性非ST段抬高型心肌梗死患者择期介入治疗中的临床意义[J].中华老年心脑血管病杂志2016,18(2):196-197.
[4]黄宇辉,许春平,曾波.急性心肌梗死介入治疗中血栓抽吸联合替罗非班的疗效分析[J].血栓与止血学,2017,23(4):577-579.
[5]张杰,宋红星,朱新锋.冠状动脉内替罗非班对急诊介入术中慢血流的影响[J].中国医药指南,2016,14(23):18-19.
[6]黄宇彬,黄余健,陈金灶.冠脉内注射替罗非班和硝普钠对PCI术中无复流的疗效[J].心血管康复医学杂志,2016,25(3):280-283.