磁共振弥散张量成像技术及其在中枢神经系统临床应用进展
摘要
<正>1994年,Basser等[1]首次提出磁共振弥散张量成像(diffusion tensor imaging,DTI)的概念,它可研究脑白质纤维的微观结构及形态结构,探测白质纤维束的生理或病理状态下的变化,并利用多参数进行定量分析。弥散张量纤维束成像(diffusion tensor tractography,DTT)是基于DTI上的一种新的可视化成像技术,是目前唯一可在活体上显示脑白质纤维束的无创性成像方法。DTI及DTT可清晰显示神经纤维束生理和病理的各向
引文
[1]Basser PJ,Mattiello J,LeBihan D.MR diffusion tensor spectroscopy and imaging.Biophys J,1994,66:259-267.
[2]L bel U,Sedlacik J,Güllmar D,et al.Diffusion tensor imaging:the normal evolution of ADC,RA,FA,and eigenvalues studied in multiple anatomical regions of the brain.Neuroradiology,2009,51:253-263.
[3]Budde MD,Xie M,Cross AH,et al.Axial diffusivity is the primary correlate of axonal injury in the experimental autoimmune encephalomyelitis spinal cord:a quantitative pixelwise analysis.J Neurosci,2009,29:2805-2813.
[4]李翠宁,刘怀军,耿左军,等.右利手年轻人脑结构DTI的T2-weighted trace图定量研究.脑与神经疾病杂志,2012,20:268-271.
[5]Michielse S,Coupland N,Camicioli R,et al.Selective effects of aging on brain white matter microstructure:a diffusion tensor imaging tractography study.Neuroimage,2010,52:1190-1201.
[6]李翠宁,刘怀军,耿左军,等.定量研究人脑投射纤维扩散张量成像与年龄的关系.河北医药,2012,34:2414-2416.
[7]Zhou J,Wang JA,Jiang B,et al.A clinical,neurolinguistic,and radiological study of a Chinese follow-up case with primary progressive aphasia.Neurocase,2013,19:427-433.
[8]龚必焱.Alzheimer病和MCI病人扣带束DTI及相关脑区静息态MRI研究.天津:天津医科大学,2011.
[9]钟进,张云亭.MR扩散张量成像在急性脑梗死的临床应用.中华放射学杂志,2005,39:677-681.
[10]王凯,赵津京,王晓东,等.急性脑卒中后DTI成像与运动神经损伤康复疗效的预测研究[J/CD].中华脑血管病杂志:电子版,2012,6:192-195.
[11]Cho SH,Kim SH,Choi BY,et al.Motor outcome according to diffusion tensor tractography findings in the early stage of intracerebral hemorrhage.Neurosci Lett,2007,421:142-146.
[12]李慧明,张珺,叶素惠.磁共振弥散张量成像研究脑桥梗死后神经纤维华勒变性及临床意义.临床和实验医学杂志,2012,11:1957-1959.
[13]Knake S,Salat DH,Halgren E,et al.Changes in white matter microstructure in patients with TLE and hippocampal sclerosis.Epileptic Disord,2009,11:244-250.
[14]朱湘文,张志强,许强,等.室管膜下型灰质异位脑纤维结构连接的MR弥散张量成像研究.中国临床神经外科杂志,2012,17:594-597.
[15]魏钦令,康庄,韩自力,等.精神分裂症早发患者脑白质的弥散张量成像研究.中华精神科杂志,2011,44:131-134.
[16]江家靖,郭文斌.抑郁症的研究进展.河北医药,2012,18:2823-2824.
[17]陈丽萍,吴卫平,郑奎洪,等.多发性硬化患者弥散张量成像及其与认知功能的关系.中国医学影像学杂志,2004,12:20-22.
[18]Shukla DK,Kaiser CC,Stebbins GT,et al.Effects of pioglitazone on diffusion tensor imaging in diffusion multiple sclerosis patients.Neurosci Lett,2010,472:153-156.
[19]索凌云,何宁,张静.新生儿缺氧缺血性脑病的MR功能成像的研究进展.中国CT和MRI杂志,2012,10:115-119.
[20]Ment LR,Hirtz D,Huppi PS.Imaging biomarkers of outcome in the developing preterm brain.Lancet Neurol,2009,8:1042-1055.
[21]Xu F,Lei D,Du X,et al.Modification of MR molecular imaging probes with cysteine-terminated peptides and their potential for in vivo tumour detection.Contrast Media Mol Imaging,2011,6:46-54.
[22]何黎明,李天栋,白红民,等.功能区胶质瘤术中应用DTI-FT导航定位和保护锥体束.中国微侵神经外科杂志,2007,12:9-12.
[23]徐庚,叶明,凌峰,等.弥散张量磁共振成像在脑胶质瘤手术中的作用.中华神经医学杂志,2006,5:918-921.
[24]Farquharson S,Tournier JD,Calamante F,et al.White matter fiber tractography:why we need to move beyond DTI.Neurosurg,2013,118:1367-1377.
[25]Feigl GC,Hiergeist W,Fellner C,et al.Magnetic Resonance Imaging Diffusion Tensor Tractography:Evaluation of Anatomic Accuracy of Different Fiber Tracking Software Packages.World Neurosurg,2013,13:11-19.
[26]Bauer MH,Kuhnt D,Barbieri S,et al.Reconstruction of White Matter Tracts via Repeated Deterministic Streamline Tracking-Initial Experience.PLoS One,2013,8:e63082.
[2]L bel U,Sedlacik J,Güllmar D,et al.Diffusion tensor imaging:the normal evolution of ADC,RA,FA,and eigenvalues studied in multiple anatomical regions of the brain.Neuroradiology,2009,51:253-263.
[3]Budde MD,Xie M,Cross AH,et al.Axial diffusivity is the primary correlate of axonal injury in the experimental autoimmune encephalomyelitis spinal cord:a quantitative pixelwise analysis.J Neurosci,2009,29:2805-2813.
[4]李翠宁,刘怀军,耿左军,等.右利手年轻人脑结构DTI的T2-weighted trace图定量研究.脑与神经疾病杂志,2012,20:268-271.
[5]Michielse S,Coupland N,Camicioli R,et al.Selective effects of aging on brain white matter microstructure:a diffusion tensor imaging tractography study.Neuroimage,2010,52:1190-1201.
[6]李翠宁,刘怀军,耿左军,等.定量研究人脑投射纤维扩散张量成像与年龄的关系.河北医药,2012,34:2414-2416.
[7]Zhou J,Wang JA,Jiang B,et al.A clinical,neurolinguistic,and radiological study of a Chinese follow-up case with primary progressive aphasia.Neurocase,2013,19:427-433.
[8]龚必焱.Alzheimer病和MCI病人扣带束DTI及相关脑区静息态MRI研究.天津:天津医科大学,2011.
[9]钟进,张云亭.MR扩散张量成像在急性脑梗死的临床应用.中华放射学杂志,2005,39:677-681.
[10]王凯,赵津京,王晓东,等.急性脑卒中后DTI成像与运动神经损伤康复疗效的预测研究[J/CD].中华脑血管病杂志:电子版,2012,6:192-195.
[11]Cho SH,Kim SH,Choi BY,et al.Motor outcome according to diffusion tensor tractography findings in the early stage of intracerebral hemorrhage.Neurosci Lett,2007,421:142-146.
[12]李慧明,张珺,叶素惠.磁共振弥散张量成像研究脑桥梗死后神经纤维华勒变性及临床意义.临床和实验医学杂志,2012,11:1957-1959.
[13]Knake S,Salat DH,Halgren E,et al.Changes in white matter microstructure in patients with TLE and hippocampal sclerosis.Epileptic Disord,2009,11:244-250.
[14]朱湘文,张志强,许强,等.室管膜下型灰质异位脑纤维结构连接的MR弥散张量成像研究.中国临床神经外科杂志,2012,17:594-597.
[15]魏钦令,康庄,韩自力,等.精神分裂症早发患者脑白质的弥散张量成像研究.中华精神科杂志,2011,44:131-134.
[16]江家靖,郭文斌.抑郁症的研究进展.河北医药,2012,18:2823-2824.
[17]陈丽萍,吴卫平,郑奎洪,等.多发性硬化患者弥散张量成像及其与认知功能的关系.中国医学影像学杂志,2004,12:20-22.
[18]Shukla DK,Kaiser CC,Stebbins GT,et al.Effects of pioglitazone on diffusion tensor imaging in diffusion multiple sclerosis patients.Neurosci Lett,2010,472:153-156.
[19]索凌云,何宁,张静.新生儿缺氧缺血性脑病的MR功能成像的研究进展.中国CT和MRI杂志,2012,10:115-119.
[20]Ment LR,Hirtz D,Huppi PS.Imaging biomarkers of outcome in the developing preterm brain.Lancet Neurol,2009,8:1042-1055.
[21]Xu F,Lei D,Du X,et al.Modification of MR molecular imaging probes with cysteine-terminated peptides and their potential for in vivo tumour detection.Contrast Media Mol Imaging,2011,6:46-54.
[22]何黎明,李天栋,白红民,等.功能区胶质瘤术中应用DTI-FT导航定位和保护锥体束.中国微侵神经外科杂志,2007,12:9-12.
[23]徐庚,叶明,凌峰,等.弥散张量磁共振成像在脑胶质瘤手术中的作用.中华神经医学杂志,2006,5:918-921.
[24]Farquharson S,Tournier JD,Calamante F,et al.White matter fiber tractography:why we need to move beyond DTI.Neurosurg,2013,118:1367-1377.
[25]Feigl GC,Hiergeist W,Fellner C,et al.Magnetic Resonance Imaging Diffusion Tensor Tractography:Evaluation of Anatomic Accuracy of Different Fiber Tracking Software Packages.World Neurosurg,2013,13:11-19.
[26]Bauer MH,Kuhnt D,Barbieri S,et al.Reconstruction of White Matter Tracts via Repeated Deterministic Streamline Tracking-Initial Experience.PLoS One,2013,8:e63082.