化学多维校正方法在药物分析中的应用
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摘要
药物研发以及药物临床试验正在不断推进,同时,药物分析基质也呈现出多样化的趋势,对不同基质中的药物进行快速和精准的定量分析具有非常重要的意义。化学多维校正方法采用"数学分离"替代或者增强传统的物理和化学分离手段,作为一种绿色的分析方法,其凭借"二阶优势",可以实现复杂体系中多组分的快速、同时、实时和原位定量分析,具有非常广阔的应用前景。本文主要综述了采用化学多维校正方法结合多种高阶分析仪器,对不同背景基质中的多组分药物进行精准定量分析的相关工作。主要包括生物基质中各类药物的含量测定,部分药物的药代动力学过程以及药物与生物大分子的相互作用过程定量监控研究,中药活性成分的含量测定以及食品和环境中的药物残留的检测等。
With the fast development of drug researches and drug clinical trials,as well as the diversification of analysis matrix,rapid and accurate quantitative analysis of drugs in different substrates is of great significance. By utilizing the smart"mathematical separation" to replace or enhance conventional physical and chemical separation means,multi-way calibration method is a green strategy with the well-known"second-order advantage".Therefore,it has a very broad prospect of applications for the fast,simultaneous,real-time and in-situ quantitative analysis of multi-components in complex systems. In this paper,related works of pharmaceutical quantitative analysis in different background matrices with multi-way calibration method coupled with high-order analytical instruments were summarized,including the determination of various drugs in biological matrices,the content of active components in traditional Chinese medicine,drug residues in food and environmental samples,and the monitoring of the pharmacokinetic process of some drugs,as well as drug-biomacromolecule interaction studies.
With the fast development of drug researches and drug clinical trials,as well as the diversification of analysis matrix,rapid and accurate quantitative analysis of drugs in different substrates is of great significance. By utilizing the smart"mathematical separation" to replace or enhance conventional physical and chemical separation means,multi-way calibration method is a green strategy with the well-known"second-order advantage".Therefore,it has a very broad prospect of applications for the fast,simultaneous,real-time and in-situ quantitative analysis of multi-components in complex systems. In this paper,related works of pharmaceutical quantitative analysis in different background matrices with multi-way calibration method coupled with high-order analytical instruments were summarized,including the determination of various drugs in biological matrices,the content of active components in traditional Chinese medicine,drug residues in food and environmental samples,and the monitoring of the pharmacokinetic process of some drugs,as well as drug-biomacromolecule interaction studies.
引文
[1]俞汝勤.化学计量学导论[M].长沙:湖南教育出版社,1991YU RQ.An Introduction to Chemometrics[M].Changsha:Hunan Education Publishing House,1991
[2]梁逸曾,俞汝勤.化学计量学[M]//分析化学手册.第十分册.第2版.北京:化学工业出版社,2000LIANG YZ,YU RQ.Chemometrics[M]//Handbook of Analytical Chemistry.Vol 10.2nd Ed.Beijing:Chemical Industry Press,2000
[3]梁逸曾,俞汝勤.化学计量学[M].北京:高等教育出版社,2003LIANG YZ,YU RQ.Chemometrics[M].Beijing:Higher Education Press,2003
[4]BOOKSH KS,KOWALSKI BR.Theory of analytical chemistry[J].Anal Chem,1994,66(15):782A
[5]WARNER IM,CHRISTIAN GD,DAVIDSON ER,et al.Analysis of multicomponent fluorescence data[J].Anal Chem,1977,49(4):564
[6]HUANG Y,WU Z,SU R,et al.Current application of chemometrics in traditional Chinese herbal medicine research[J].J Chromatogr B,2016,1026:27
[7]杨婷婷,袁峰泉,金荣庆,等.绿色分析技术及其在药物分析中的应用研究进展[J].药物分析杂志,2015,35(12):2070YANG TT,YUAN FQ,JIN RQ,et al.Advances in green analytical techniques and their applications in pharmaceutical analysis[J].Chin J Pharm Anal,2015,35(12):2070
[8]金力超,范玉明,侯晓蓉,等.色谱联用技术在药物分析中的应用特点和新趋势[J].药物分析杂志,2015,35(9):1520JIN LC,FAN YM,HOU XR,et al.Application and tendency of chromatographic hyphenated techniques in pharmaceutical analysis[J].Chin J Pharm Anal,2015,35(9):1520
[9]魏学敏,吴倩,刘强,等.化学计量学-光谱法在药物分析中的应用进展[J].药物分析杂志,2013,33(8):1447WEI XM,WU Q,LIU Q,et al.Progress on application of chemometrics-spectrometry in pharmaceutical analysis[J].Chin JPharm Anal,2013,33(8):1447
[10]魏文峰,王昶,张树明,等.基于化学计量学与代谢组学方法的中药分析研究进展[J].中国中医药信息杂志,2013,20(10):108WEI WF,WANG C,ZHANG SM,et al.Research progress of traditional Chinese medicine based on chemometrics and metabolomics methods[J].Chin J Inf TCM,2013,20(10):108
[11]宋清,陆峰.独立组分分析的十种算法综述及其在药物分析中的应用[J].药学实践杂志,2013,31(1):1SONG Q,LU F.Application of ten independent component analysis methods in pharmaceutical analysis[J].J Pharm Pract,2013,31(1):1
[12]李晓冰,石富国,宋沁馨,等.药物分析研究进展[J].药学进展,2013,37(8):360LI XB,SHI FG,SONG QX,et al.Progress in pharmaceutical analysis[J].Prog Pharm Sci,2013,37(8):360
[13]ROGGO Y,CHALUS P,MAURER L,et al.A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies[J].J Pharm Biomed Anal,2007,44(3):683
[14]GABRIELSSON J,LINDBERG NO,LUNDSTEDT T.Multivariate methods in pharmaceutical applications[J].J Chemom,2002,16(3):141
[15]MONAKHOVA YB,HOLZGRABE U,DIEHL BWK.Current role and future perspectives of multivariate(chemometric)methods in NMR spectroscopic analysis of pharmaceutical products[J].JPharm Biomed Anal,2018,147:580
[16]RAJALAHTI T,KVALHEIM OM.Multivariate data analysis in pharmaceutics:a tutorial review[J].Int J Pharm,2011,417(1-2):280
[17]GINDY AEL,HADAD GM.Chemometrics in pharmaceutical analysis:an introduction,review,and future perspectives[J].JAOAC Int,2012,95(3):609
[18]CALVO NL,MAGGIO RM,KAUFMAN TS.Characterization of pharmaceutically relevant materials at the solid state employing chemometrics methods[J].J Pharm Biomed Anal,2018,147:538
[19]GOICOECHEA HC,CULZONI MJ,GARCIA MD,et al.Chemometric strategies for enhancing the chromatographic methodologies with second-order data analysis of compounds when peaks are overlapped[J].Talanta,2011,83(4):1098
[20]AZZOUZ T,TAULER R.Application of multivariate curve resolution alternating least squares(MCR-ALS)to the quantitative analysis of pharmaceutical and agricultural samples[J].Talanta,2008,74(5):1201
[21]GóMEZ V,CALLAO MP.Analytical applications of second-order calibration methods[J].Anal Chim Acta,2008,627(2):169
[22]ESCANDAR GM,DAMIANI PC,GOICOECHEA HC,et al.Areview of multivariate calibration methods applied to biomedical analysis[J].Microchem J,2006,82(1):29
[23]LIANG YZ,WU HL,SHEN GL,et al.Aspects of recent developments in analytical chemometrics[J].Sci China Ser B,2006,49(3):193
[24]WU HL,NIE JF,YU YJ,et al.Multi-way chemometric methodologies and applications:a central summary of our research work[J].Anal Chim Acta,2009,650(1):131
[25]WU HL,LI Y,YU RQ.Recent developments of chemical multiway calibration methodologies with second-order or higher-order advantages[J].J Chemom,2014,28(5):476
[26]吴海龙,李勇,康超,等.三维荧光化学多维校正方法研究新进展[J].分析化学,2015,43(11):1629WU HL,LI Y,KANG C,et al.Research progress of threedimensional fluorescence coupled with chemical multiway calibration[J].Chin J Anal Chem,2015,43(11):1629
[27]WU HL,YIN XL,GU HW,et al.Chemometrics in Bioanalytical Chemistry[M]//Encyclopedia of Analytical Chemistry,2016
[28]梁逸曾,吴海龙,俞汝勤.化学计量学[M]//分析化学手册.第十分册.第3版.北京:化学工业出版社,2016LIANG YZ,WU HL,YU RQ.Chemometrics[M]//Handbook of Analytical Chemistry.Vol 10.3rd Ed.Beijing:Chemical Industry Press,2016
[29]袁丽.抗肿瘤药研发线与趋势[N].医药经济报,2016-08-24(4)YUAN L.R&D lines and trends of antitumor drugs[N].Medicine Economic Reporter,2016-08-24(4)
[30]HURTADO-SANCHEZ MC,DURAN-MERAS I,RODRIGUEZ-CACERES MI,et al.Comparison of the predictive ability of several second-order multivariate methods in the simultaneous determination of two therapeutic drugs in human urine[J].Talanta,2012,88(1):609
[31]BRO R.PARAFAC.Tutorial and applications[J].Chemom Intell Lab Syst,1997,38(2):149
[32]OLIVIERI AC.On a versatile second-order multivariate calibration method based on partial least-squares and residual bilinearization:second-order advantage and precision properties[J].J Chemom,2005,19(4):253
[33]SCHENONE AV,CULZONI MJ,CAMPIGLIA AD,et al.Total synchronous fluorescence spectroscopic data modeled with firstand second-order algorithms for the determination of doxorubicin in human plasma[J].Anal Bioanal Chem,2013,405(26):8515
[34]XIA AL,WU HL,FANG DM,et al.Determination of daunomycin in human plasma and urine by using an interference-free analysis of excitation-emission matrix fluorescence data with second-order calibration[J].Anal Sci,2006,22(9):1189
[35]FU HY,WU HL,NIE JF,et al.Highly sensitive fluorescence quantification of irinotecan in biological fluids with the aid of second-order advantage[J].Chin Chem Lett,2010,21(12):1482
[36]XIA AL,WU HL,ZHU SH,et al.Determination of psoralen in human plasma using excitation-emission matrix fluorescence coupled to second-order calibration[J].Anal Sci,2008,24(9):1171
[37]尹小丽,吴海龙,张晓华,等.三维荧光二阶校正同时测定人体液中伊立替康及其代谢物7-乙基-10-羟基喜树碱的含量[J].化学学报,2013,71(4):560YIN XL,WU HL,ZHANG XH,et al.Simultaneous determination of irinotecan and its metabolite 7-ethyl-10-hydroxycamptothecin in biological fluids using excitation-emission matrix fluorescence coupled with second-order calibration method[J].Acta Chim Sin,2013,71(4):560
[38]王予,吴海龙,于永杰,等.三维荧光光谱结合交替三线性分解二阶校正法同时测定血浆样中三种抗癌药物含量[J].中国科学:化学,2012,42(8):1226WANG Y,WU HL,YU YJ,et al.Simultaneous determination of three anticancerogens in plasma samples using second-order calibration method based on alternating trilinear decomposition coupled with fluorescence spectroscopy[J].Sci Sin Chim,2012,42(8):1226
[39]XIANG SX,WU HL,KANG C,et al.Fast quantitative analysis of four tyrosine kinase inhibitors in different human plasma samples using three-way calibration-assisted liquid chromatography with diode array detection[J].J Sep Sci,2015,38(16):2781
[40]WU HL,SHIBUKAWA M,OGUMA K.An alternating trilinear decomposition algorithm with application to calibration of HPLC-DAD for simultaneous determination of overlapped chlorinated aromatic hydrocarbons[J].J Chemom,1998,12(1):1
[41]LIU Z,WU HL,LI Y,et al.Rapid and simultaneous determination of five vinca alkaloids in Catharanthus roseus and human serum using trilinear component modeling of liquid chromatography-diode array detection data[J].J Chromatogr B,2016,1026:114
[42]吴颖仪.全球心血管药物Top10[N].医药经济报,2017-10-30(F 04)WU YY.Global cardiovascular drug Top10[N].Medicine Economic Reporter,2017-10-30(F 04)
[43]ZHANG Y,WU HL,XIA AL,et al.Fluorescence determination of metoprolol in human plasma by trilinear decomposition-based calibration techniques[J].Anal Bioanal Chem,2006,386(6):1741
[44]GU HW,WU HL,LIU YJ,et al.Simultaneous determination of metoprolol andα-hydroxymetoprolol in human plasma using excitation-emission matrix fluorescence coupled with second-order calibration methods[J].Bioanalysis,2012,4(23):2781
[45]XIE HP,CHU X,JIANG JH,et al.Competitive interactions of adriamycin and ethidium bromide with DNA as studied by full rank parallel factor analysis of fluorescence three-way array data[J].Spectrochim Acta Part A Mol Biomol Spectrosc,2003,59(4):743
[46]韩清娟,吴海龙,聂瑾芳,等.三维荧光校正法直接测定尿液中的利血平[J].高等学校化学学报,2007,28(5):827HAN QJ,WU HL,NIE JF,et al.Direct determination of reserpine in urine using excitation-emission fluorescence combined with three-dimensional chemometric calibration methodologies[J].Chem J Chin Univ,2007,28(5):827
[47]HAN QJ,WU HL,NIE JF,et al.Direct determination of reserpine in urine using excitation-emission fluorescence combined with three-way chemometric calibration methodologies[J].Front Chem China,2008,3(2):224
[48]CHEN ZP,WU HL,JIANG JH,et al.A novel trilinear decomposition algorithm for second-order linear calibration[J].Chemom Intell Lab Syst,2000,52(1):75
[49]赵娟,吴海龙,于丽丽,等.三维荧光二阶校正法用于复杂基体样中川芎嗪和替米沙坦的快速定量分析[J].分析科学学报,2011,27(3):273ZHAO J,WU HL,YU LL,et al.Rapid quantitative analysis of ligustrazine and telmisartan in complex samples using excitationemission matrix fluorescence coupled with second-order calibration method[J].J Anal Sci,2011,27(3):273
[50]XIAO R,WU HL,HU Y,et al.Simultaneous determination of warfarin and aspirin contents in biological fluids using excitationemission matrix fluorescence coupled with a second-order calibration method[J].Anal Sci,2017,33(1):29
[51]DAMIANI PC.Determination of atenolol in human urine by emission-excitation fluorescence matrices and unfolded partial least-squares with residual bilinearization[J].Talanta,2011,85(3):1526
[52]ZOU HY,WU HL,OUYANG LQ,et al.Fluorescent quantification of terazosin hydrochloride content in human plasma and tablets using second-order calibration based on both parallel factor analysis and alternating penalty trilinear decomposition[J].Anal Chim Acta,2009,650(1):143
[53]BOOKSH K,HENSHAW JM,BURGESS LW,et al.A secondorder standard addition method with application to calibration of a kinetics-spectroscopic sensor for quantitation of trichloroethylene[J].J Chemom,1995,9(4):263
[54]XIA AL,WU HL,FANG DM,et al.Alternating penalty trilinear decomposition algorithm for second-order calibration with application to interference-free analysis of excitation-emission matrix fluorescence data[J].J Chemom,2005,19(2):65
[55]VALDERRAMA P,POPPI RJ.Determination of propranolol enantiomers in plasma and urine by spectrofluorimetry and secondorder standard addition method[J].Anal Chim Acta,2009,651(1):31
[56]LI SF,WU HL,YU YJ,et al.Quantitative analysis of levodopa,carbidopa and methyldopa in human plasma samples using HPLC-DAD combined with second-order calibration based on alternating trilinear decomposition algorithm[J].Talanta,2010,81(3):805
[57]ZHAO J,WU HL,NIU JF,et al.Chemometric resolution of coeluting peaks of eleven antihypertensives from multiple classes in high performance liquid chromatography:a comprehensive research in human serum,health product and Chinese patent medicine samples[J].J Chromatogr B,2012,902:96
[58]GU HW,WU HL,YIN XL,et al.Multi-targeted interferencefree determination of ten beta-blockers in human urine and plasma samples by alternating trilinear decomposition algorithm-assisted liquid chromatography-mass spectrometry in full scan mode:comparison with multiple reaction monitoring[J].Anal Chim Acta,2014,848:10
[59]王燕芳.浅析抗感染药引起不良反应的条件及特点[J].求医问药,2013,11(4):295WANG YF.Analysis of the conditions and characteristics of adverse drug reactions by anti-infectives[J].Seek Med Ask Med,2013,11(4):295
[60]ORTIZ MC,SARABIA LA,SANCHEZ MS,et al.Identification and quantification of ciprofloxacin in urine through excitation-emission fluorescence and three-way PARAFAC calibration[J].Anal Chim Acta,2009,642(1-2):193
[61]FANG DM,WU HL,DING YJ,et al.Interference-free determination of fluoroquinolone antibiotics in plasma by using excitation-emission matrix fluorescence coupled with second-order calibration algorithms[J].Talanta,2006,70(1):58
[62]PAGANI AP,IBAEZ GA.Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices.Analysis of fluoroquinolones in the presence of significant spectral overlapping[J].Microchem J,2017,132:211
[63]OLIVIERI AC,ARANCIBIA JA,PENA AM,et al.Second-order advantage achieved with four-way fluorescence excitation-emissionkinetic data processed by parallel factor analysis and trilinear leastsquares.Determination of methotrexate and leucovorin in human urine[J].Anal Chem,2004,76(19):5657
[64]宋晶晶,吴海龙,于永杰,等.三维荧光光谱二阶校正方法测定血浆样中喷昔洛韦及泛昔洛韦含量[J].中国科学:化学,2010,40(8):1136SONG JJ,WU HL,YU YJ,et al.Determination of famciclovir and penciclovir in human plasma samples by using excitation-emission matrix fluorescent spectracoupled with second-order calibration[J].Sci Sin Chim,2010,40(8):1136
[65]BRO R,KIERS HAL.A new efficient method for determining the number of components in PARAFAC models[J].J Chemom,2003,17(5):274
[66]CANADA-CANADA F,ARANCIBIA JA,ESCANDAR GM,et al.Second-order multivariate calibration procedures applied to high-performance liquid chromatography coupled to fast-scanning fluorescence detection for the determination of fluoroquinolones[J].J Chromatogr A,2009,1216(24):4868
[67]TAULER R.Multivariate curve resolution applied to second order data[J].Chemom Intell Lab Syst,1995,30(1):133
[68]OUYANG LQ,WU HL,LIU YJ,et al.Simultaneous determination of metronidazole and tinidazole in plasma by using HPLC-DADcoupled with second-order calibration[J].Chin Chem Lett,2010,21(10):1223
[69]ZHANG XH,WU HL,WANG JY,et al.Second-order calibration applied to quantification of two active components of Schisandra chinensis in complex matrix[J].J Pharm Anal,2012,2(4):241
[70]张晓华,吴海龙,王建瑶,等.三维荧光二阶校正方法用于体液和细胞培养基中五味子甲素含量的快速测定[J].高等学校化学学报,2011,32(8):1720ZHANG XH,WU HL,WANG JY,et al.Determination of schizandrin A in body fluids and cell culture media by excitationemission matrix fluorescence coupled with second-order calibration[J].Chem J Chin Univ,2011,32(8):1720
[71]LIU YJ,WU HL,KANG C,et al.Four-way self-weighted alternating normalized residue fitting algorithm with application for the analysis of serotonin in human plasma[J].Anal Sci,2012,28(11):1097
[72]WANG L,WU HL,YIN XL,et al.Simultaneous determination of umbelliferone and scopoletin in Tibetan medicine Saussurea laniceps and traditional Chinese medicine Radix Angelicae Pubescentis using excitation-emission matrix fluorescence coupled with secondorder calibration method[J].Spectrochim Acta Part A Mol Biomol Spectrosc,2017,170:104
[73]HU Y,WU HL,YIN XL,et al.Interference-free spectrofluorometric quantification of aristolochic acidⅠand aristololactamⅠin five Chinese herbal medicines using chemical derivatization enhancement and second-order calibration methods[J].Spectrochim Acta Part AMol Biomol Spectrosc,2017,175:229
[74]OUYANG LQ,WU HL,NIE JF,et al.Simultaneous determination of psoralen and isopsoralen in plasma and Chinese medicine Xian Ling Gu Bao capsule by using HPLC-DAD coupled with alternating trilinear decomposition algorithm[J].Anal Chim Acta,2009,650(2):160
[75]LIU Y,WU H,ZHU S,et al.Rapid determination of costunolide and dehydrocostuslactone in human plasma sample and Chinese patent medicine Xiang Sha Yang Wei capsule using HPLC-DADcoupled with second-order calibration[J].Chin J Chem,2012,30(5):1137
[76]MAHEDERO MC,DIAZ NM,PENA AM,et al.Strategies for solving matrix effects in the analysis of sulfathiazole in honey samples using three-way photochemically induced fluorescence data[J].Talanta,2005,65(3):806
[77]YU YJ,WU HL,SHAO SZ,et al.Using second-order calibration method based on trilinear decomposition algorithms coupled with high performance liquid chromatography with diode array detector for determination of quinolones in honey samples[J].Talanta,2011,85(3):1549
[78]NI YN,GU Y,KOKOT S.Multiway calibrations based on spectrofluorimetric data derived from kinetic analysis of the hydrolysis reaction of nitrofurans-A comparison of prediction performance[J].Chemom Intell Lab Syst,2012,112:55
[79]YU YJ,WU HL,FU HY,et al.Chromatographic background drift correction coupled with parallel factor analysis to resolve coelution problems in three-dimensional chromatographic data:quantification of eleven antibiotics in tap water samples by high-performance liquid chromatography coupled with a diode array detector[J].JChromatogr A,2013,1302:72
[80]OLIVIERI AC,ARANCIBIA JA,PENA AM,et al.Second-order advantage achieved with four-way fluorescence excitation-emissionkinetic data processed by parallel factor analysis and trilinear leastsquares.Determination of methotrexate and leucovorin in human urine[J].Anal Chem,2004,76(19):5657
[81]ARANCIBIA JA,OLIVIERI AC,GIL DB,et al.Trilinear leastsquares and unfolded-PLS coupled to residual trilinearization:new chemometric tools for the analysis of four-way instrumental data[J].Chemom Intell Lab Syst,2006,80(1):77
[82]李淑芳,吴海龙,夏阿林,等.荧光动力学二阶校正法定量分析人血浆样中去甲肾上腺素[J].化学学报,2008,66(8):947LI SF,WU HL,XIA AL,et al.Quantitative analysis of noradrenaline in human plasma samples using kinetic fluorometric methods coupled with second-order calibration[J].Acta Chim Sin,2008,66(8):947
[83]LI SF,WU HL,XIA AL,et al.Quantitative analysis of epinephrine in human plasma samples using kinetic fluorometric method combined with second-order calibration[J].Anal Sci,2009,25(10):1231
[84]LI SF,WU HL,HUANG L,et al.Quantitative analysis of fluphenazine hydrochloride in human urine using excitation-emission matrix fluorescence based on oxidation derivatization and combined with second-order calibration methods[J].Anal Methods,2010,2(8):1069
[85]XIE LX,WU HL,FANG Y,et al.Simultaneous determination of tyrosine and levodopa in human plasma using enzyme-induced excitation-emission-kinetic third-order calibration method[J].Chemom Intell Lab Syst,2015,148:9
[86]QING XD,WU HL,YAN XF,et al.Development of a novel alternating quadrilinear decomposition algorithm for the kinetic analysis of four-way room-temperature phosphorescence data[J].Chemom Intell Lab Syst,2014,132(3):8
[87]LUCA MD,MAS S,IOELE G,et al.Kinetic studies of nitrofurazone photodegradation by multivariate curve resolution applied to UV-spectral data[J].Int J Pharm,2010,386(1-2):99
[88]YIN XL,WU HL,GU HW,et al.Second-order calibration method applied to process three-way excitation-emission-kinetic fluorescence data:a novel tool for real-time quantitative analysis of the lactone hydrolysis of irinotecan in human plasma[J].Chemom Intell Lab Syst,2015,146:447
[89]YIN XL,GU HW,LIU XL,et al.Comparison of three-way and four-way calibration for the real-time quantitative analysis of drug hydrolysis in complex dynamic samples by excitation-emission matrix fluorescence[J].Spectrochim Acta Part A Mol Biomol Spectrosc,2018,192(Supplement C):437
[90]KANG C,WU HL,ZHOU C,et al.Quantitative fluorescence kinetic analysis of NADH and FAD in human plasma using three-and fourway calibration methods capable of providing the second-order advantage[J].Anal Chim Acta,2016,910:36
[91]XIA AL,WU HL,LI SF,et al.Study of the interactions of berberine and daunorubicin with DNA using alternating penalty trilinear decomposition algorithm combined with excitation-emission matrix fluorescence data[J].Talanta,2007,73(4):606
[92]ZOU HY,WU HL,ZHANG Y,et al.Studying the interaction of pirarubicin with DNA and determining pirarubicin in human urine samples:combining excitation-emission fluorescence matrices with second-order calibration methods[J].J Fluoresc,2009,19(6):955
[93]WANG Y,ZHU R,NI Y,et al.Competitive interactions of anti-carcinogens with serum albumin:a spectroscopic study of bendamustine and dexamethasone with the aid of chemometrics[J].Spectrochim Acta Part A Mol Biomol Spectrosc,2014,123:241
[94]ZHAI M,WU H,ZHANG S,et al.Interaction of epicatechin with bovine serum albumin using fluorescence quenching combined with chemometrics[J].Sci China Chem,2013,57(5):748
[95]XIE LX,WU HL,KANG C,et al.Quantitative investigation of the dynamic interaction of human serum albumin with procaine using a multi-way calibration method coupled with three-dimensional fluorescence spectroscopy[J].Anal Methods,2015,7(16):6552
[96]吴海龙,莫翠云,曹玉珍,等.交替三线性分解校正法与荧光分析法相结合同时测定阿米洛利、心得安和潘生丁[J].计算机与应用化学,2002,19(1):15WU HL,MO CY,CAO YZ,et al.Simultaneous spectrofluorimetric determination of amiloride propranolol and dipyridamole using alternating trilinear decomposition alorithm[J].Comput Appl Chem,2002,19(1):15
[97]NIE JF,WU HL,XIA AL,et al.Determination of sulpiride in human urine using excitation-emission matrix fluorescence coupled with second-order calibration[J].Anal Sci,2007,23(12):1377
[98]张喜华,吴海龙,康超,等.化学计量学二阶校正法结合三维荧光光谱技术同时快速测定人血清样中西酞普兰、氟西汀和帕罗西汀含量[J].精细化工中间体,2013,43(1):63ZHANG XH,WU HL,KANG C,et al.Simultaneous and rapid determination of citalopram,fluoxetine and paroxetine contents in human serum samples using three-dimensional fluorescence technique coupled with chemometric secondorder calibration[J].Fine Chem Intermed,2013,43(1):63
[99]邵圣枝,吴海龙,李淑芳,等.三维荧光二阶校正法用于尿液样和血浆样中左旋多巴的定量测定[J].分析科学学报,2010,26(4):373SHAO SZ,WU HL,LI SF,et al.Determination of levodopa in both human urine and plasma samples using excitation-emission matrix fluorescence coupled with second-order calibration[J].J Anal Sci,2010,26(4):373
[100]LI SS,WU HL,LIU YJ,et al.Simultaneous determination of tyrosine and dopamine in urine samples using excitation-emission matrix fluorescence coupled with second-order calibration[J].Chin Chem Lett,2013,24(3):239
[101]ZOU HY,WU HL,LI YN,et al.Simultaneous determination of dextromethorphan and quinidine contents in biological fluid samples using excitation-emission matrix fluorescence coupled with second-order calibration methods[J].Anal Lett,2010,43(17):2739
[102]LIU YJ,WU HL,NIE JF,et al.Simultaneous determination of dextromethorphan and its metabolite dextrorphan in plasma samples using second-order calibration coupled with excitation-emission matrix fluorescence[J].Anal Sci,2011,27(6):663
[103]曹莹,吴海龙,朱绍华,等.三维荧光二阶校正法用于尿液样中氢化可的松的定量测定[J].分析科学学报,2008,24(6):621CAO Y,WU HL,ZHU SH,et al.Quantitative analysis of hydrocortisone in urine sample using three-dimensional fluorescence spectrum analysis coupled with second-order calibration[J].J Anal Sci,2008,24(6):621
[104]ZHANG Y,WU HL,DING YJ,et al.Simultaneous determination of cortisol and prednisolone in body fluids by using HPLC-DADcoupled with second-order calibration based on alternating trilinear decomposition[J].J Chromatogr B,2006,840(2):116
[105]GU HW,WU HL,LI SS,et al.Chemometrics-enhanced full scan mode of liquid chromatography-mass spectrometry for the simultaneous determination of six co-eluted sulfonylurea-type oral antidiabetic agents in complex samples[J].Chemom Intell Lab Syst,2016,155:62
[106]YU YJ,WU HL,KANG C,et al.Algorithm combination strategy to obtain the second-order advantage:simultaneous determination of target analytes in plasma using three-dimensional fluorescence spectroscopy[J].J Chemom,2012,26(5):197
[107]HU Y,WU HL,YIN XL,et al.Chemometrics-assisted determination of amiloride and triamterene in biological fluids with overlapped peaks and unknown interferences[J].Bioanalysis,2015,7(13):1685
[108]于丽丽,吴海龙,付海燕,等.三维荧光二阶校正法快速测定人尿样中奥沙普秦含量[J].分析化学,2011,39(1):27YU LL,WU HL,FU HY,et al.Rapid determination of oxaprozin contents in urine and combined pharmacotherapy samples using three-dimensional fluorescence coupled with second-order calibration methods[J].Chin J Anal Chem,2011,39(1):27
[109]王童,吴海龙,谢丽霞,等.三维荧光二阶校正法同时快速测定人体液中两种非甾体抗炎药萘普生和二氟尼柳[J].精细化工中间体,2017,47(5):79WANG T,WU HL,XIE LX,et al.Fast and simultaneous determination of naproxen and diflunisal in biological fluids using excitation-emission matrix fluorescence coupled with second-order calibration method[J].Fine Chem Intermed,2017,47(5):79
[110]WANG T,WU HL,XIE LX,et al.Simultaneous and interferencefree determination of eleven non-steroidal anti-inflammatory drugs illegally added into Chinese patent drugs using chemometricsassisted HPLC-DAD strategy[J].Sci China Chem,2018,61(6):739
[111]CHEN Y,WU HL,WANG J,et al.Chemometrics-assisted excitation-emission fluorescence spectroscopy for simultaneous determination of ethoxyquin and tert-butylhydroquinone in biological fluid samples[J].Sci China Chem,2012,56(5):664
[112]KANG C,WU HL,XIANG SX,et al.Simultaneous determination of aromatic amino acids in different systems using three-way calibration based on the PARAFAC-ALS algorithm coupled with EEM fluorescence:exploration of second-order advantages[J].Anal Methods,2014,6(16):6358
[113]KANG C,WU HL,XIE LX,et al.Direct quantitative analysis of aromatic amino acids in human plasma by four-way calibration using intrinsic fluorescence:exploration of third-order advantages[J].Talanta,2014,122:293
[114]XIA H,WU HL,GU HW,et al.Simultaneous determination of naphazoline and pyridoxine in eye drops using excitation-emission matrix fluorescence coupled with second-order calibration method based on alternating trilinear decomposition algorithm[J].Chin Chem Let,2015,26(12):1446
[115]张燕,吴海龙,欧阳立群,等.激发-发射矩阵荧光结合二阶校正法测定人体血浆样和牛蒡子药材中的牛蒡苷含量[J].计算机与应用化学,2009,26(6):697ZHANG Y,WU HL,OUYANG LQ,et al.Determination of arctiin in plasma samples and Arctium lappa L.by using excitation-emission matrix fluoresence and second-order calibration based on parallel factor analysis/alternating normalization-weighted error algorithms[J].Comput Appl Chem,2009,26(6):697
[116]吴海龙,张娟,王建瑶,等.三维荧光二阶校正测定细胞培养基样中山姜素[J].湖南大学学报(自然科学版),2011,38(8):50WU HL,ZHANG J,WANG JY,et al.Determination of alpinetin in cell culture medium samples by using three-dimensional fluorescence coupled with second-order calibration[J].J Hunan Univ(Nat Sci),2011,38(8):50
[117]牛景芳,吴海龙,于永杰,等.三维荧光二阶校正法直接快速测定血浆样中川芎嗪和阿魏酸含量[J].计算机与应用化学,2011,28(5):3NIU JF,WU HL,YU YJ,et al.Simultaneous determination of ligustrazine and ferulic acid in human plasma samples by combining excitation-emission matrix fluorescence with second-order calibration[J].Comput Appl Chem,2011,28(5):3
[118]江军朵,吴海龙,夏阿林,等.三维荧光光谱结合二阶校正算法测定人体血浆和厚朴药材中的厚朴酚及和厚朴酚[J].高等学校化学学报,2008,29(1):71JIANG JD,WU HL,XIA AL,et al.Determination of honokiol and magnolol in both human plasma and Cortex Magnoliae Officinalis by second-order calibration coupled to three-dimensional excitationemission fluorescence spectra[J].Chem J Chin Univ,2008,29(1):71
[119]孙翔宇,吴海龙,陆剑忠,等.三维荧光光谱法结合交替三线性分解算法同时分辨及定量测定秦皮中的秦皮甲素和秦皮乙素成分[J].分析科学学报,2005,21(2):149SUN XY,WU HL,LU JZ,et al.Simultaneous resolution and determination of aesculin and aesculetin in Cortex Fraxini by emission-excitation matrix fluorometry coupled with alternating trilinear decomposition algorithm[J].J Anal Sci,2005,21(2):149
[120]翟敏,吴海龙,方焕,等.三维荧光光谱结合交替三线性分解方法同时测定人血浆样中姜黄素和双去甲氧基姜黄素含量[J].精细化工中间体,2015,45(5):63ZHAI M,WU HL,FANG H,et al.Rapid quantitative analysis of curcumin and bisdemethoxy-curcumin in human plasma samples using excitation-emission matrix fluorescence coupled with alternating trilinear decomposition method[J].Fine Chem Intermed,2015,45(5):63
[121]许慧,吴海龙,刘亚娟,等.高效液相色谱-二极管阵列检测方法结合交替三线性分解算法快速定量测定中药黄芩中的黄芩素和汉黄芩素[J].精细化工中间体,2011,41(2):68XU H,WU HL,LIU YJ,et al.Simultaneous determination of baicalein and wogonin in Chinese medicinal plant Scutellaria baicalensis using HPLC-DAD coupled with alternating trilinear decomposition[J].Fine Chem Intermed,2011,41(2):68
[122]苏志义,吴海龙,刘亚娟,等.HPLC-DAD结合交替三线性分解二阶校正方法进行中药葛根中主要有效成分同时测定[J].化学学报,2012,70(4):459SU ZY,WU HL,LIU YJ,et al.Simultaneous determination of main effective constituents in traditional Chinese medicine kudzuvine root using HPLC-DAD coupled with second-order calibration based on alternating trilinear decomposition[J].Acta Chim Sin,2012,70(4):459
[123]ZHANG XH,WU HL,YIN XL,et al.Exploiting third-order advantage using four-way calibration method for direct quantitative analysis of active ingredients of Schisandra chinensis in DMEM by processing four-way excitation-emission-solvent fluorescence data[J].Chemom Intell Lab Syst,2016,155:46
[2]梁逸曾,俞汝勤.化学计量学[M]//分析化学手册.第十分册.第2版.北京:化学工业出版社,2000LIANG YZ,YU RQ.Chemometrics[M]//Handbook of Analytical Chemistry.Vol 10.2nd Ed.Beijing:Chemical Industry Press,2000
[3]梁逸曾,俞汝勤.化学计量学[M].北京:高等教育出版社,2003LIANG YZ,YU RQ.Chemometrics[M].Beijing:Higher Education Press,2003
[4]BOOKSH KS,KOWALSKI BR.Theory of analytical chemistry[J].Anal Chem,1994,66(15):782A
[5]WARNER IM,CHRISTIAN GD,DAVIDSON ER,et al.Analysis of multicomponent fluorescence data[J].Anal Chem,1977,49(4):564
[6]HUANG Y,WU Z,SU R,et al.Current application of chemometrics in traditional Chinese herbal medicine research[J].J Chromatogr B,2016,1026:27
[7]杨婷婷,袁峰泉,金荣庆,等.绿色分析技术及其在药物分析中的应用研究进展[J].药物分析杂志,2015,35(12):2070YANG TT,YUAN FQ,JIN RQ,et al.Advances in green analytical techniques and their applications in pharmaceutical analysis[J].Chin J Pharm Anal,2015,35(12):2070
[8]金力超,范玉明,侯晓蓉,等.色谱联用技术在药物分析中的应用特点和新趋势[J].药物分析杂志,2015,35(9):1520JIN LC,FAN YM,HOU XR,et al.Application and tendency of chromatographic hyphenated techniques in pharmaceutical analysis[J].Chin J Pharm Anal,2015,35(9):1520
[9]魏学敏,吴倩,刘强,等.化学计量学-光谱法在药物分析中的应用进展[J].药物分析杂志,2013,33(8):1447WEI XM,WU Q,LIU Q,et al.Progress on application of chemometrics-spectrometry in pharmaceutical analysis[J].Chin JPharm Anal,2013,33(8):1447
[10]魏文峰,王昶,张树明,等.基于化学计量学与代谢组学方法的中药分析研究进展[J].中国中医药信息杂志,2013,20(10):108WEI WF,WANG C,ZHANG SM,et al.Research progress of traditional Chinese medicine based on chemometrics and metabolomics methods[J].Chin J Inf TCM,2013,20(10):108
[11]宋清,陆峰.独立组分分析的十种算法综述及其在药物分析中的应用[J].药学实践杂志,2013,31(1):1SONG Q,LU F.Application of ten independent component analysis methods in pharmaceutical analysis[J].J Pharm Pract,2013,31(1):1
[12]李晓冰,石富国,宋沁馨,等.药物分析研究进展[J].药学进展,2013,37(8):360LI XB,SHI FG,SONG QX,et al.Progress in pharmaceutical analysis[J].Prog Pharm Sci,2013,37(8):360
[13]ROGGO Y,CHALUS P,MAURER L,et al.A review of near infrared spectroscopy and chemometrics in pharmaceutical technologies[J].J Pharm Biomed Anal,2007,44(3):683
[14]GABRIELSSON J,LINDBERG NO,LUNDSTEDT T.Multivariate methods in pharmaceutical applications[J].J Chemom,2002,16(3):141
[15]MONAKHOVA YB,HOLZGRABE U,DIEHL BWK.Current role and future perspectives of multivariate(chemometric)methods in NMR spectroscopic analysis of pharmaceutical products[J].JPharm Biomed Anal,2018,147:580
[16]RAJALAHTI T,KVALHEIM OM.Multivariate data analysis in pharmaceutics:a tutorial review[J].Int J Pharm,2011,417(1-2):280
[17]GINDY AEL,HADAD GM.Chemometrics in pharmaceutical analysis:an introduction,review,and future perspectives[J].JAOAC Int,2012,95(3):609
[18]CALVO NL,MAGGIO RM,KAUFMAN TS.Characterization of pharmaceutically relevant materials at the solid state employing chemometrics methods[J].J Pharm Biomed Anal,2018,147:538
[19]GOICOECHEA HC,CULZONI MJ,GARCIA MD,et al.Chemometric strategies for enhancing the chromatographic methodologies with second-order data analysis of compounds when peaks are overlapped[J].Talanta,2011,83(4):1098
[20]AZZOUZ T,TAULER R.Application of multivariate curve resolution alternating least squares(MCR-ALS)to the quantitative analysis of pharmaceutical and agricultural samples[J].Talanta,2008,74(5):1201
[21]GóMEZ V,CALLAO MP.Analytical applications of second-order calibration methods[J].Anal Chim Acta,2008,627(2):169
[22]ESCANDAR GM,DAMIANI PC,GOICOECHEA HC,et al.Areview of multivariate calibration methods applied to biomedical analysis[J].Microchem J,2006,82(1):29
[23]LIANG YZ,WU HL,SHEN GL,et al.Aspects of recent developments in analytical chemometrics[J].Sci China Ser B,2006,49(3):193
[24]WU HL,NIE JF,YU YJ,et al.Multi-way chemometric methodologies and applications:a central summary of our research work[J].Anal Chim Acta,2009,650(1):131
[25]WU HL,LI Y,YU RQ.Recent developments of chemical multiway calibration methodologies with second-order or higher-order advantages[J].J Chemom,2014,28(5):476
[26]吴海龙,李勇,康超,等.三维荧光化学多维校正方法研究新进展[J].分析化学,2015,43(11):1629WU HL,LI Y,KANG C,et al.Research progress of threedimensional fluorescence coupled with chemical multiway calibration[J].Chin J Anal Chem,2015,43(11):1629
[27]WU HL,YIN XL,GU HW,et al.Chemometrics in Bioanalytical Chemistry[M]//Encyclopedia of Analytical Chemistry,2016
[28]梁逸曾,吴海龙,俞汝勤.化学计量学[M]//分析化学手册.第十分册.第3版.北京:化学工业出版社,2016LIANG YZ,WU HL,YU RQ.Chemometrics[M]//Handbook of Analytical Chemistry.Vol 10.3rd Ed.Beijing:Chemical Industry Press,2016
[29]袁丽.抗肿瘤药研发线与趋势[N].医药经济报,2016-08-24(4)YUAN L.R&D lines and trends of antitumor drugs[N].Medicine Economic Reporter,2016-08-24(4)
[30]HURTADO-SANCHEZ MC,DURAN-MERAS I,RODRIGUEZ-CACERES MI,et al.Comparison of the predictive ability of several second-order multivariate methods in the simultaneous determination of two therapeutic drugs in human urine[J].Talanta,2012,88(1):609
[31]BRO R.PARAFAC.Tutorial and applications[J].Chemom Intell Lab Syst,1997,38(2):149
[32]OLIVIERI AC.On a versatile second-order multivariate calibration method based on partial least-squares and residual bilinearization:second-order advantage and precision properties[J].J Chemom,2005,19(4):253
[33]SCHENONE AV,CULZONI MJ,CAMPIGLIA AD,et al.Total synchronous fluorescence spectroscopic data modeled with firstand second-order algorithms for the determination of doxorubicin in human plasma[J].Anal Bioanal Chem,2013,405(26):8515
[34]XIA AL,WU HL,FANG DM,et al.Determination of daunomycin in human plasma and urine by using an interference-free analysis of excitation-emission matrix fluorescence data with second-order calibration[J].Anal Sci,2006,22(9):1189
[35]FU HY,WU HL,NIE JF,et al.Highly sensitive fluorescence quantification of irinotecan in biological fluids with the aid of second-order advantage[J].Chin Chem Lett,2010,21(12):1482
[36]XIA AL,WU HL,ZHU SH,et al.Determination of psoralen in human plasma using excitation-emission matrix fluorescence coupled to second-order calibration[J].Anal Sci,2008,24(9):1171
[37]尹小丽,吴海龙,张晓华,等.三维荧光二阶校正同时测定人体液中伊立替康及其代谢物7-乙基-10-羟基喜树碱的含量[J].化学学报,2013,71(4):560YIN XL,WU HL,ZHANG XH,et al.Simultaneous determination of irinotecan and its metabolite 7-ethyl-10-hydroxycamptothecin in biological fluids using excitation-emission matrix fluorescence coupled with second-order calibration method[J].Acta Chim Sin,2013,71(4):560
[38]王予,吴海龙,于永杰,等.三维荧光光谱结合交替三线性分解二阶校正法同时测定血浆样中三种抗癌药物含量[J].中国科学:化学,2012,42(8):1226WANG Y,WU HL,YU YJ,et al.Simultaneous determination of three anticancerogens in plasma samples using second-order calibration method based on alternating trilinear decomposition coupled with fluorescence spectroscopy[J].Sci Sin Chim,2012,42(8):1226
[39]XIANG SX,WU HL,KANG C,et al.Fast quantitative analysis of four tyrosine kinase inhibitors in different human plasma samples using three-way calibration-assisted liquid chromatography with diode array detection[J].J Sep Sci,2015,38(16):2781
[40]WU HL,SHIBUKAWA M,OGUMA K.An alternating trilinear decomposition algorithm with application to calibration of HPLC-DAD for simultaneous determination of overlapped chlorinated aromatic hydrocarbons[J].J Chemom,1998,12(1):1
[41]LIU Z,WU HL,LI Y,et al.Rapid and simultaneous determination of five vinca alkaloids in Catharanthus roseus and human serum using trilinear component modeling of liquid chromatography-diode array detection data[J].J Chromatogr B,2016,1026:114
[42]吴颖仪.全球心血管药物Top10[N].医药经济报,2017-10-30(F 04)WU YY.Global cardiovascular drug Top10[N].Medicine Economic Reporter,2017-10-30(F 04)
[43]ZHANG Y,WU HL,XIA AL,et al.Fluorescence determination of metoprolol in human plasma by trilinear decomposition-based calibration techniques[J].Anal Bioanal Chem,2006,386(6):1741
[44]GU HW,WU HL,LIU YJ,et al.Simultaneous determination of metoprolol andα-hydroxymetoprolol in human plasma using excitation-emission matrix fluorescence coupled with second-order calibration methods[J].Bioanalysis,2012,4(23):2781
[45]XIE HP,CHU X,JIANG JH,et al.Competitive interactions of adriamycin and ethidium bromide with DNA as studied by full rank parallel factor analysis of fluorescence three-way array data[J].Spectrochim Acta Part A Mol Biomol Spectrosc,2003,59(4):743
[46]韩清娟,吴海龙,聂瑾芳,等.三维荧光校正法直接测定尿液中的利血平[J].高等学校化学学报,2007,28(5):827HAN QJ,WU HL,NIE JF,et al.Direct determination of reserpine in urine using excitation-emission fluorescence combined with three-dimensional chemometric calibration methodologies[J].Chem J Chin Univ,2007,28(5):827
[47]HAN QJ,WU HL,NIE JF,et al.Direct determination of reserpine in urine using excitation-emission fluorescence combined with three-way chemometric calibration methodologies[J].Front Chem China,2008,3(2):224
[48]CHEN ZP,WU HL,JIANG JH,et al.A novel trilinear decomposition algorithm for second-order linear calibration[J].Chemom Intell Lab Syst,2000,52(1):75
[49]赵娟,吴海龙,于丽丽,等.三维荧光二阶校正法用于复杂基体样中川芎嗪和替米沙坦的快速定量分析[J].分析科学学报,2011,27(3):273ZHAO J,WU HL,YU LL,et al.Rapid quantitative analysis of ligustrazine and telmisartan in complex samples using excitationemission matrix fluorescence coupled with second-order calibration method[J].J Anal Sci,2011,27(3):273
[50]XIAO R,WU HL,HU Y,et al.Simultaneous determination of warfarin and aspirin contents in biological fluids using excitationemission matrix fluorescence coupled with a second-order calibration method[J].Anal Sci,2017,33(1):29
[51]DAMIANI PC.Determination of atenolol in human urine by emission-excitation fluorescence matrices and unfolded partial least-squares with residual bilinearization[J].Talanta,2011,85(3):1526
[52]ZOU HY,WU HL,OUYANG LQ,et al.Fluorescent quantification of terazosin hydrochloride content in human plasma and tablets using second-order calibration based on both parallel factor analysis and alternating penalty trilinear decomposition[J].Anal Chim Acta,2009,650(1):143
[53]BOOKSH K,HENSHAW JM,BURGESS LW,et al.A secondorder standard addition method with application to calibration of a kinetics-spectroscopic sensor for quantitation of trichloroethylene[J].J Chemom,1995,9(4):263
[54]XIA AL,WU HL,FANG DM,et al.Alternating penalty trilinear decomposition algorithm for second-order calibration with application to interference-free analysis of excitation-emission matrix fluorescence data[J].J Chemom,2005,19(2):65
[55]VALDERRAMA P,POPPI RJ.Determination of propranolol enantiomers in plasma and urine by spectrofluorimetry and secondorder standard addition method[J].Anal Chim Acta,2009,651(1):31
[56]LI SF,WU HL,YU YJ,et al.Quantitative analysis of levodopa,carbidopa and methyldopa in human plasma samples using HPLC-DAD combined with second-order calibration based on alternating trilinear decomposition algorithm[J].Talanta,2010,81(3):805
[57]ZHAO J,WU HL,NIU JF,et al.Chemometric resolution of coeluting peaks of eleven antihypertensives from multiple classes in high performance liquid chromatography:a comprehensive research in human serum,health product and Chinese patent medicine samples[J].J Chromatogr B,2012,902:96
[58]GU HW,WU HL,YIN XL,et al.Multi-targeted interferencefree determination of ten beta-blockers in human urine and plasma samples by alternating trilinear decomposition algorithm-assisted liquid chromatography-mass spectrometry in full scan mode:comparison with multiple reaction monitoring[J].Anal Chim Acta,2014,848:10
[59]王燕芳.浅析抗感染药引起不良反应的条件及特点[J].求医问药,2013,11(4):295WANG YF.Analysis of the conditions and characteristics of adverse drug reactions by anti-infectives[J].Seek Med Ask Med,2013,11(4):295
[60]ORTIZ MC,SARABIA LA,SANCHEZ MS,et al.Identification and quantification of ciprofloxacin in urine through excitation-emission fluorescence and three-way PARAFAC calibration[J].Anal Chim Acta,2009,642(1-2):193
[61]FANG DM,WU HL,DING YJ,et al.Interference-free determination of fluoroquinolone antibiotics in plasma by using excitation-emission matrix fluorescence coupled with second-order calibration algorithms[J].Talanta,2006,70(1):58
[62]PAGANI AP,IBAEZ GA.Four-way calibration applied to the processing of pH-modulated fluorescence excitation-emission matrices.Analysis of fluoroquinolones in the presence of significant spectral overlapping[J].Microchem J,2017,132:211
[63]OLIVIERI AC,ARANCIBIA JA,PENA AM,et al.Second-order advantage achieved with four-way fluorescence excitation-emissionkinetic data processed by parallel factor analysis and trilinear leastsquares.Determination of methotrexate and leucovorin in human urine[J].Anal Chem,2004,76(19):5657
[64]宋晶晶,吴海龙,于永杰,等.三维荧光光谱二阶校正方法测定血浆样中喷昔洛韦及泛昔洛韦含量[J].中国科学:化学,2010,40(8):1136SONG JJ,WU HL,YU YJ,et al.Determination of famciclovir and penciclovir in human plasma samples by using excitation-emission matrix fluorescent spectracoupled with second-order calibration[J].Sci Sin Chim,2010,40(8):1136
[65]BRO R,KIERS HAL.A new efficient method for determining the number of components in PARAFAC models[J].J Chemom,2003,17(5):274
[66]CANADA-CANADA F,ARANCIBIA JA,ESCANDAR GM,et al.Second-order multivariate calibration procedures applied to high-performance liquid chromatography coupled to fast-scanning fluorescence detection for the determination of fluoroquinolones[J].J Chromatogr A,2009,1216(24):4868
[67]TAULER R.Multivariate curve resolution applied to second order data[J].Chemom Intell Lab Syst,1995,30(1):133
[68]OUYANG LQ,WU HL,LIU YJ,et al.Simultaneous determination of metronidazole and tinidazole in plasma by using HPLC-DADcoupled with second-order calibration[J].Chin Chem Lett,2010,21(10):1223
[69]ZHANG XH,WU HL,WANG JY,et al.Second-order calibration applied to quantification of two active components of Schisandra chinensis in complex matrix[J].J Pharm Anal,2012,2(4):241
[70]张晓华,吴海龙,王建瑶,等.三维荧光二阶校正方法用于体液和细胞培养基中五味子甲素含量的快速测定[J].高等学校化学学报,2011,32(8):1720ZHANG XH,WU HL,WANG JY,et al.Determination of schizandrin A in body fluids and cell culture media by excitationemission matrix fluorescence coupled with second-order calibration[J].Chem J Chin Univ,2011,32(8):1720
[71]LIU YJ,WU HL,KANG C,et al.Four-way self-weighted alternating normalized residue fitting algorithm with application for the analysis of serotonin in human plasma[J].Anal Sci,2012,28(11):1097
[72]WANG L,WU HL,YIN XL,et al.Simultaneous determination of umbelliferone and scopoletin in Tibetan medicine Saussurea laniceps and traditional Chinese medicine Radix Angelicae Pubescentis using excitation-emission matrix fluorescence coupled with secondorder calibration method[J].Spectrochim Acta Part A Mol Biomol Spectrosc,2017,170:104
[73]HU Y,WU HL,YIN XL,et al.Interference-free spectrofluorometric quantification of aristolochic acidⅠand aristololactamⅠin five Chinese herbal medicines using chemical derivatization enhancement and second-order calibration methods[J].Spectrochim Acta Part AMol Biomol Spectrosc,2017,175:229
[74]OUYANG LQ,WU HL,NIE JF,et al.Simultaneous determination of psoralen and isopsoralen in plasma and Chinese medicine Xian Ling Gu Bao capsule by using HPLC-DAD coupled with alternating trilinear decomposition algorithm[J].Anal Chim Acta,2009,650(2):160
[75]LIU Y,WU H,ZHU S,et al.Rapid determination of costunolide and dehydrocostuslactone in human plasma sample and Chinese patent medicine Xiang Sha Yang Wei capsule using HPLC-DADcoupled with second-order calibration[J].Chin J Chem,2012,30(5):1137
[76]MAHEDERO MC,DIAZ NM,PENA AM,et al.Strategies for solving matrix effects in the analysis of sulfathiazole in honey samples using three-way photochemically induced fluorescence data[J].Talanta,2005,65(3):806
[77]YU YJ,WU HL,SHAO SZ,et al.Using second-order calibration method based on trilinear decomposition algorithms coupled with high performance liquid chromatography with diode array detector for determination of quinolones in honey samples[J].Talanta,2011,85(3):1549
[78]NI YN,GU Y,KOKOT S.Multiway calibrations based on spectrofluorimetric data derived from kinetic analysis of the hydrolysis reaction of nitrofurans-A comparison of prediction performance[J].Chemom Intell Lab Syst,2012,112:55
[79]YU YJ,WU HL,FU HY,et al.Chromatographic background drift correction coupled with parallel factor analysis to resolve coelution problems in three-dimensional chromatographic data:quantification of eleven antibiotics in tap water samples by high-performance liquid chromatography coupled with a diode array detector[J].JChromatogr A,2013,1302:72
[80]OLIVIERI AC,ARANCIBIA JA,PENA AM,et al.Second-order advantage achieved with four-way fluorescence excitation-emissionkinetic data processed by parallel factor analysis and trilinear leastsquares.Determination of methotrexate and leucovorin in human urine[J].Anal Chem,2004,76(19):5657
[81]ARANCIBIA JA,OLIVIERI AC,GIL DB,et al.Trilinear leastsquares and unfolded-PLS coupled to residual trilinearization:new chemometric tools for the analysis of four-way instrumental data[J].Chemom Intell Lab Syst,2006,80(1):77
[82]李淑芳,吴海龙,夏阿林,等.荧光动力学二阶校正法定量分析人血浆样中去甲肾上腺素[J].化学学报,2008,66(8):947LI SF,WU HL,XIA AL,et al.Quantitative analysis of noradrenaline in human plasma samples using kinetic fluorometric methods coupled with second-order calibration[J].Acta Chim Sin,2008,66(8):947
[83]LI SF,WU HL,XIA AL,et al.Quantitative analysis of epinephrine in human plasma samples using kinetic fluorometric method combined with second-order calibration[J].Anal Sci,2009,25(10):1231
[84]LI SF,WU HL,HUANG L,et al.Quantitative analysis of fluphenazine hydrochloride in human urine using excitation-emission matrix fluorescence based on oxidation derivatization and combined with second-order calibration methods[J].Anal Methods,2010,2(8):1069
[85]XIE LX,WU HL,FANG Y,et al.Simultaneous determination of tyrosine and levodopa in human plasma using enzyme-induced excitation-emission-kinetic third-order calibration method[J].Chemom Intell Lab Syst,2015,148:9
[86]QING XD,WU HL,YAN XF,et al.Development of a novel alternating quadrilinear decomposition algorithm for the kinetic analysis of four-way room-temperature phosphorescence data[J].Chemom Intell Lab Syst,2014,132(3):8
[87]LUCA MD,MAS S,IOELE G,et al.Kinetic studies of nitrofurazone photodegradation by multivariate curve resolution applied to UV-spectral data[J].Int J Pharm,2010,386(1-2):99
[88]YIN XL,WU HL,GU HW,et al.Second-order calibration method applied to process three-way excitation-emission-kinetic fluorescence data:a novel tool for real-time quantitative analysis of the lactone hydrolysis of irinotecan in human plasma[J].Chemom Intell Lab Syst,2015,146:447
[89]YIN XL,GU HW,LIU XL,et al.Comparison of three-way and four-way calibration for the real-time quantitative analysis of drug hydrolysis in complex dynamic samples by excitation-emission matrix fluorescence[J].Spectrochim Acta Part A Mol Biomol Spectrosc,2018,192(Supplement C):437
[90]KANG C,WU HL,ZHOU C,et al.Quantitative fluorescence kinetic analysis of NADH and FAD in human plasma using three-and fourway calibration methods capable of providing the second-order advantage[J].Anal Chim Acta,2016,910:36
[91]XIA AL,WU HL,LI SF,et al.Study of the interactions of berberine and daunorubicin with DNA using alternating penalty trilinear decomposition algorithm combined with excitation-emission matrix fluorescence data[J].Talanta,2007,73(4):606
[92]ZOU HY,WU HL,ZHANG Y,et al.Studying the interaction of pirarubicin with DNA and determining pirarubicin in human urine samples:combining excitation-emission fluorescence matrices with second-order calibration methods[J].J Fluoresc,2009,19(6):955
[93]WANG Y,ZHU R,NI Y,et al.Competitive interactions of anti-carcinogens with serum albumin:a spectroscopic study of bendamustine and dexamethasone with the aid of chemometrics[J].Spectrochim Acta Part A Mol Biomol Spectrosc,2014,123:241
[94]ZHAI M,WU H,ZHANG S,et al.Interaction of epicatechin with bovine serum albumin using fluorescence quenching combined with chemometrics[J].Sci China Chem,2013,57(5):748
[95]XIE LX,WU HL,KANG C,et al.Quantitative investigation of the dynamic interaction of human serum albumin with procaine using a multi-way calibration method coupled with three-dimensional fluorescence spectroscopy[J].Anal Methods,2015,7(16):6552
[96]吴海龙,莫翠云,曹玉珍,等.交替三线性分解校正法与荧光分析法相结合同时测定阿米洛利、心得安和潘生丁[J].计算机与应用化学,2002,19(1):15WU HL,MO CY,CAO YZ,et al.Simultaneous spectrofluorimetric determination of amiloride propranolol and dipyridamole using alternating trilinear decomposition alorithm[J].Comput Appl Chem,2002,19(1):15
[97]NIE JF,WU HL,XIA AL,et al.Determination of sulpiride in human urine using excitation-emission matrix fluorescence coupled with second-order calibration[J].Anal Sci,2007,23(12):1377
[98]张喜华,吴海龙,康超,等.化学计量学二阶校正法结合三维荧光光谱技术同时快速测定人血清样中西酞普兰、氟西汀和帕罗西汀含量[J].精细化工中间体,2013,43(1):63ZHANG XH,WU HL,KANG C,et al.Simultaneous and rapid determination of citalopram,fluoxetine and paroxetine contents in human serum samples using three-dimensional fluorescence technique coupled with chemometric secondorder calibration[J].Fine Chem Intermed,2013,43(1):63
[99]邵圣枝,吴海龙,李淑芳,等.三维荧光二阶校正法用于尿液样和血浆样中左旋多巴的定量测定[J].分析科学学报,2010,26(4):373SHAO SZ,WU HL,LI SF,et al.Determination of levodopa in both human urine and plasma samples using excitation-emission matrix fluorescence coupled with second-order calibration[J].J Anal Sci,2010,26(4):373
[100]LI SS,WU HL,LIU YJ,et al.Simultaneous determination of tyrosine and dopamine in urine samples using excitation-emission matrix fluorescence coupled with second-order calibration[J].Chin Chem Lett,2013,24(3):239
[101]ZOU HY,WU HL,LI YN,et al.Simultaneous determination of dextromethorphan and quinidine contents in biological fluid samples using excitation-emission matrix fluorescence coupled with second-order calibration methods[J].Anal Lett,2010,43(17):2739
[102]LIU YJ,WU HL,NIE JF,et al.Simultaneous determination of dextromethorphan and its metabolite dextrorphan in plasma samples using second-order calibration coupled with excitation-emission matrix fluorescence[J].Anal Sci,2011,27(6):663
[103]曹莹,吴海龙,朱绍华,等.三维荧光二阶校正法用于尿液样中氢化可的松的定量测定[J].分析科学学报,2008,24(6):621CAO Y,WU HL,ZHU SH,et al.Quantitative analysis of hydrocortisone in urine sample using three-dimensional fluorescence spectrum analysis coupled with second-order calibration[J].J Anal Sci,2008,24(6):621
[104]ZHANG Y,WU HL,DING YJ,et al.Simultaneous determination of cortisol and prednisolone in body fluids by using HPLC-DADcoupled with second-order calibration based on alternating trilinear decomposition[J].J Chromatogr B,2006,840(2):116
[105]GU HW,WU HL,LI SS,et al.Chemometrics-enhanced full scan mode of liquid chromatography-mass spectrometry for the simultaneous determination of six co-eluted sulfonylurea-type oral antidiabetic agents in complex samples[J].Chemom Intell Lab Syst,2016,155:62
[106]YU YJ,WU HL,KANG C,et al.Algorithm combination strategy to obtain the second-order advantage:simultaneous determination of target analytes in plasma using three-dimensional fluorescence spectroscopy[J].J Chemom,2012,26(5):197
[107]HU Y,WU HL,YIN XL,et al.Chemometrics-assisted determination of amiloride and triamterene in biological fluids with overlapped peaks and unknown interferences[J].Bioanalysis,2015,7(13):1685
[108]于丽丽,吴海龙,付海燕,等.三维荧光二阶校正法快速测定人尿样中奥沙普秦含量[J].分析化学,2011,39(1):27YU LL,WU HL,FU HY,et al.Rapid determination of oxaprozin contents in urine and combined pharmacotherapy samples using three-dimensional fluorescence coupled with second-order calibration methods[J].Chin J Anal Chem,2011,39(1):27
[109]王童,吴海龙,谢丽霞,等.三维荧光二阶校正法同时快速测定人体液中两种非甾体抗炎药萘普生和二氟尼柳[J].精细化工中间体,2017,47(5):79WANG T,WU HL,XIE LX,et al.Fast and simultaneous determination of naproxen and diflunisal in biological fluids using excitation-emission matrix fluorescence coupled with second-order calibration method[J].Fine Chem Intermed,2017,47(5):79
[110]WANG T,WU HL,XIE LX,et al.Simultaneous and interferencefree determination of eleven non-steroidal anti-inflammatory drugs illegally added into Chinese patent drugs using chemometricsassisted HPLC-DAD strategy[J].Sci China Chem,2018,61(6):739
[111]CHEN Y,WU HL,WANG J,et al.Chemometrics-assisted excitation-emission fluorescence spectroscopy for simultaneous determination of ethoxyquin and tert-butylhydroquinone in biological fluid samples[J].Sci China Chem,2012,56(5):664
[112]KANG C,WU HL,XIANG SX,et al.Simultaneous determination of aromatic amino acids in different systems using three-way calibration based on the PARAFAC-ALS algorithm coupled with EEM fluorescence:exploration of second-order advantages[J].Anal Methods,2014,6(16):6358
[113]KANG C,WU HL,XIE LX,et al.Direct quantitative analysis of aromatic amino acids in human plasma by four-way calibration using intrinsic fluorescence:exploration of third-order advantages[J].Talanta,2014,122:293
[114]XIA H,WU HL,GU HW,et al.Simultaneous determination of naphazoline and pyridoxine in eye drops using excitation-emission matrix fluorescence coupled with second-order calibration method based on alternating trilinear decomposition algorithm[J].Chin Chem Let,2015,26(12):1446
[115]张燕,吴海龙,欧阳立群,等.激发-发射矩阵荧光结合二阶校正法测定人体血浆样和牛蒡子药材中的牛蒡苷含量[J].计算机与应用化学,2009,26(6):697ZHANG Y,WU HL,OUYANG LQ,et al.Determination of arctiin in plasma samples and Arctium lappa L.by using excitation-emission matrix fluoresence and second-order calibration based on parallel factor analysis/alternating normalization-weighted error algorithms[J].Comput Appl Chem,2009,26(6):697
[116]吴海龙,张娟,王建瑶,等.三维荧光二阶校正测定细胞培养基样中山姜素[J].湖南大学学报(自然科学版),2011,38(8):50WU HL,ZHANG J,WANG JY,et al.Determination of alpinetin in cell culture medium samples by using three-dimensional fluorescence coupled with second-order calibration[J].J Hunan Univ(Nat Sci),2011,38(8):50
[117]牛景芳,吴海龙,于永杰,等.三维荧光二阶校正法直接快速测定血浆样中川芎嗪和阿魏酸含量[J].计算机与应用化学,2011,28(5):3NIU JF,WU HL,YU YJ,et al.Simultaneous determination of ligustrazine and ferulic acid in human plasma samples by combining excitation-emission matrix fluorescence with second-order calibration[J].Comput Appl Chem,2011,28(5):3
[118]江军朵,吴海龙,夏阿林,等.三维荧光光谱结合二阶校正算法测定人体血浆和厚朴药材中的厚朴酚及和厚朴酚[J].高等学校化学学报,2008,29(1):71JIANG JD,WU HL,XIA AL,et al.Determination of honokiol and magnolol in both human plasma and Cortex Magnoliae Officinalis by second-order calibration coupled to three-dimensional excitationemission fluorescence spectra[J].Chem J Chin Univ,2008,29(1):71
[119]孙翔宇,吴海龙,陆剑忠,等.三维荧光光谱法结合交替三线性分解算法同时分辨及定量测定秦皮中的秦皮甲素和秦皮乙素成分[J].分析科学学报,2005,21(2):149SUN XY,WU HL,LU JZ,et al.Simultaneous resolution and determination of aesculin and aesculetin in Cortex Fraxini by emission-excitation matrix fluorometry coupled with alternating trilinear decomposition algorithm[J].J Anal Sci,2005,21(2):149
[120]翟敏,吴海龙,方焕,等.三维荧光光谱结合交替三线性分解方法同时测定人血浆样中姜黄素和双去甲氧基姜黄素含量[J].精细化工中间体,2015,45(5):63ZHAI M,WU HL,FANG H,et al.Rapid quantitative analysis of curcumin and bisdemethoxy-curcumin in human plasma samples using excitation-emission matrix fluorescence coupled with alternating trilinear decomposition method[J].Fine Chem Intermed,2015,45(5):63
[121]许慧,吴海龙,刘亚娟,等.高效液相色谱-二极管阵列检测方法结合交替三线性分解算法快速定量测定中药黄芩中的黄芩素和汉黄芩素[J].精细化工中间体,2011,41(2):68XU H,WU HL,LIU YJ,et al.Simultaneous determination of baicalein and wogonin in Chinese medicinal plant Scutellaria baicalensis using HPLC-DAD coupled with alternating trilinear decomposition[J].Fine Chem Intermed,2011,41(2):68
[122]苏志义,吴海龙,刘亚娟,等.HPLC-DAD结合交替三线性分解二阶校正方法进行中药葛根中主要有效成分同时测定[J].化学学报,2012,70(4):459SU ZY,WU HL,LIU YJ,et al.Simultaneous determination of main effective constituents in traditional Chinese medicine kudzuvine root using HPLC-DAD coupled with second-order calibration based on alternating trilinear decomposition[J].Acta Chim Sin,2012,70(4):459
[123]ZHANG XH,WU HL,YIN XL,et al.Exploiting third-order advantage using four-way calibration method for direct quantitative analysis of active ingredients of Schisandra chinensis in DMEM by processing four-way excitation-emission-solvent fluorescence data[J].Chemom Intell Lab Syst,2016,155:46