贵州黔南地区农村少数民族居民功能性消化不良患病现状及其危险因素分析
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摘要
目的了解贵州黔南地区农村少数民族居民功能性消化不良患病现状及其危险因素,为采取相应的干预措施提供参考依据。方法于2016年10月—2017年12月,采用整群随机抽样方法,在贵州黔南地区抽取98 877名≥20岁农村常住少数民族居民进行问卷调查、体格检查和其他诊断性检查。结果贵州黔南地区98 877名常住农村少数民族居民中,患功能性消化不良者18 432例,患病率为18.64%,标化患病率为18.59%;多因素非条件logistic回归分析结果显示,女性(OR=3.334,95%CI=1.237~5.883)、年龄40~79岁(OR=2.195~4.628)、布依族(OR=3.411,95%CI=1.635~5.195)、水族(OR=2.524,95%CI=1.034~3.572)、文化程度小学及以下(OR=3.424,95%CI=1.535~3.074)、有家族史(OR=3.415,95%CI=1.321~5.897)、体质指数(BMI)为消瘦(OR=3.306,95%CI=1.122~4.969)、喜欢咸性食物(OR=3.901,95%CI=1.431~4.706)、喜欢生冷食物(OR=3.862,95%CI=1.352~5.989)、劳动强度Ⅰ级(OR=3.321,95%CI=1.243~4.197)、每日饮水量<500 m L(OR=3.226,95%CI=1.227~4.778)、每日睡眠时间<5 h(OR=3.764,95%CI=1.232~5.009)、长期服用药物(OR=2.867,95%CI=1.245~3.782)、便秘(OR=3.157,95%CI=1.339~5.812)、长期紧张或焦虑(OR=4.511,95%CI=1.542~6.998)和居住海拔高度>1 500 m(OR=3.483,95%CI=1.335~4.792)是贵州黔南地区农村少数民族居民功能性消化不良患病的危险因素。结论贵州黔南地区农村少数民族居民功能性消化不良患病率较高,应针对该地区少数民族居民功能性消化不良患病的危险因素进行干预。
Objective To examine the prevalence and risk factors of functional dyspepsia among minority rural residents living in southern area of Guizhou province and to provide references for taking corresponding interventions. Methods A total of 98 877 minority permanent rural residents( ≥ 20 years old) were randomly selected with cluster random sampling from Qiannan prefecture of Guizhou province and surveyed with a face-to-face interview,physical examination,and other diagnostic tests between October 2016 and December 2017. Results Totally 18 432 functional dyspepsia(FD) cases were diagnosed; the prevalence rate of FD was 18.64% and the standardized prevalence rate was 18.59% among the participants.Unconditional multivariate logistic regression analysis revealed following risk factors of FD: female gender(odds ratio[OR] = 3.334, 95% confidence interval [95% CI]: 1.237 – 5.883), age 40 – 79 years(OR = 2.195 – 4.628),Buyi nationality(OR = 3.411, 95% CI: 1.635 – 5.195), Shui nationality(OR = 2.524, 95% CI: 1.034 – 3.572), education of primary school and below(OR = 3.424, 95% CI: 1.535 – 3.074), family history of FD(OR = 3.415, 95% CI: 1.321 – 5.897), body mass indexbased emaciation(OR = 3.306, 95% CI: 1.122 – 4.969), preference for salty food(OR = 3.901, 95% CI: 1.431 – 4.706),preference for cold and uncooked food(OR = 3.862, 95% CI: 1.352 – 5.989), having light physical labor(OR = 3.321, 95%CI: 1.243 – 4.197), drinking water < 500 ml per day(OR = 3.226, 95% CI: 1.227 – 4.778), with sleeping time of < 5 hours per day(OR = 3.764, 95% CI: 1.232 – 5.009), taking medicine for a long time(OR = 2.867, 95% CI: 1245 – 3.782),constipation(OR = 3.157, 95% CI: 1.339 – 5.812), and with long duration of stress or anxiety(OR = 4.511, 95% CI: 1.542 –6.998); the analysis also showed that living in an area with the altitude of higher than 1 500 meters was a protective factor for FD(OR = 3.483, 95% CI: 1.335 – 4.792). Conclusion The prevalence rate of functional dyspepsia is relative high among minority rural residents living in southern area of Guizhou province and interventions on risk factors of functional dyspepsia should be conducted among the population.
Objective To examine the prevalence and risk factors of functional dyspepsia among minority rural residents living in southern area of Guizhou province and to provide references for taking corresponding interventions. Methods A total of 98 877 minority permanent rural residents( ≥ 20 years old) were randomly selected with cluster random sampling from Qiannan prefecture of Guizhou province and surveyed with a face-to-face interview,physical examination,and other diagnostic tests between October 2016 and December 2017. Results Totally 18 432 functional dyspepsia(FD) cases were diagnosed; the prevalence rate of FD was 18.64% and the standardized prevalence rate was 18.59% among the participants.Unconditional multivariate logistic regression analysis revealed following risk factors of FD: female gender(odds ratio[OR] = 3.334, 95% confidence interval [95% CI]: 1.237 – 5.883), age 40 – 79 years(OR = 2.195 – 4.628),Buyi nationality(OR = 3.411, 95% CI: 1.635 – 5.195), Shui nationality(OR = 2.524, 95% CI: 1.034 – 3.572), education of primary school and below(OR = 3.424, 95% CI: 1.535 – 3.074), family history of FD(OR = 3.415, 95% CI: 1.321 – 5.897), body mass indexbased emaciation(OR = 3.306, 95% CI: 1.122 – 4.969), preference for salty food(OR = 3.901, 95% CI: 1.431 – 4.706),preference for cold and uncooked food(OR = 3.862, 95% CI: 1.352 – 5.989), having light physical labor(OR = 3.321, 95%CI: 1.243 – 4.197), drinking water < 500 ml per day(OR = 3.226, 95% CI: 1.227 – 4.778), with sleeping time of < 5 hours per day(OR = 3.764, 95% CI: 1.232 – 5.009), taking medicine for a long time(OR = 2.867, 95% CI: 1245 – 3.782),constipation(OR = 3.157, 95% CI: 1.339 – 5.812), and with long duration of stress or anxiety(OR = 4.511, 95% CI: 1.542 –6.998); the analysis also showed that living in an area with the altitude of higher than 1 500 meters was a protective factor for FD(OR = 3.483, 95% CI: 1.335 – 4.792). Conclusion The prevalence rate of functional dyspepsia is relative high among minority rural residents living in southern area of Guizhou province and interventions on risk factors of functional dyspepsia should be conducted among the population.
引文
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[6]Shaib Y,El-Serag HB.The prevalence and risk factors of functional dyspepsia in a multiethnic population in the United States[J].American Journal of Gastroenterology,2004,99(11):2210-2216.
[7]王万梁.单项体力劳动强度分级研究[D].济南:山东大学,2007.
[8]左国文,梁列新,姚萍,等.南宁市大学生功能性消化不良的流行病学调查[J].世界华人消化杂志,2014,22(1):263-267.
[9]符春平,赵锡林,赵宏福,等.贵州黔南地区农村居民肛肠疾病患病现状及危险因素[J].中国公共卫生,2015,31(4):397-400.
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[12]Kawamura A,Adachi K,Takashima T,et al.Prevalence of functional dyspepsia and its relationship with Helicobacter pylori infection in a Japanese population[J].J Gastroenterol Hepatol,2010,26(4):384-388.
[13]吴柏瑶,张法灿,梁列新.功能性消化不良的流行病学[J].胃肠病学和肝病学杂志,2013,22(1):85-88.
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[15]Mahadeva S,Yadav H,Rampal S,et al.Ethnic variation,epidemiological factors and quality of life impairment associated with dyspepsiain urban Malaysia[J].Aliment Pharmacol Ther,2010,31(10):1141-1151.
[16]王瑞,唐承薇.雌激素与功能性消化不良关系研究[J].中国实用内科杂志,2008,28(6):578-579.
[17]易宗华,程德金,杨雯,等.武汉医学生常见功能性胃肠病患病情况及相关因素研究[J].湖北中医药大学学报,2016,18(6):95-97.
[18]Zhao YF,Ma XQ,Wang R,et al.Epidemiology of functional constipation and comparison with constipation-predominant irritable bowel syndrome:the Systematic Investigation of Gastrointestinal Diseases in China(SILC)[J].Alimentary Pharmacology and Therapeutics,2011,34(8):1020-1029.
[19]Park JW,Cho YS,Lee SY,et al.Concomitant functional gastrointestinal symptoms influence psychological status in Korean migraine patients[J].Gut and Liver,2013,7(6):668-674.
[20]谢晓铿,梁谷,郑琴芳,等.南宁市良庆社区居民FGIDs发生率及相关因素分析[J].广西医学,2013,35(7):831-833.
[2]Tack J,Talley NJ,Camilleri M,et al.Functional gastroduodenal disorders[J].Gastroenterology,2016,130(5):1466-1479.
[3]姚萍,梁列新,董卫国,等.广西隆安县农村壮族人群功能性消化不良的流行病学调查[J].世界华人消化杂志,2014,22(17):2393-2398.
[4]Ghoshal UC,Singh R,Chang FY,et al.Epidemiology of uninvestigated and functional dyspepsia in Asia:facts and fiction[J].Journal of Neurogastroenterology and Motility,2011,17(3):235-244.
[5]杨通宇,陈新春,刘照时,等.少数民族地区农村女性骨质疏松患病及影响因素分析[J].中国公共卫生,2016,32(3):266-269.
[6]Shaib Y,El-Serag HB.The prevalence and risk factors of functional dyspepsia in a multiethnic population in the United States[J].American Journal of Gastroenterology,2004,99(11):2210-2216.
[7]王万梁.单项体力劳动强度分级研究[D].济南:山东大学,2007.
[8]左国文,梁列新,姚萍,等.南宁市大学生功能性消化不良的流行病学调查[J].世界华人消化杂志,2014,22(1):263-267.
[9]符春平,赵锡林,赵宏福,等.贵州黔南地区农村居民肛肠疾病患病现状及危险因素[J].中国公共卫生,2015,31(4):397-400.
[10]黔南州统计局.贵州省黔南州2010年第六次人口普查主要数据公报(第1期)(内部资料)[M].都匀:黔南州统计局,2011:25.
[11]Lee SY,Lee KJ,Kim SJ,et al.Prevalence and risk factors for overlaps between gastroesophageal reflux disease,dyspepsia,and irritable bowel syndrome:a population-based study[J].Digestion,2009,79(3):196-201.
[12]Kawamura A,Adachi K,Takashima T,et al.Prevalence of functional dyspepsia and its relationship with Helicobacter pylori infection in a Japanese population[J].J Gastroenterol Hepatol,2010,26(4):384-388.
[13]吴柏瑶,张法灿,梁列新.功能性消化不良的流行病学[J].胃肠病学和肝病学杂志,2013,22(1):85-88.
[14]贺丽,苏丹,张恩,等.出租车司机功能性胃肠病患病情况调查[J].中国公共卫生,2010,26(11):1466-1467.
[15]Mahadeva S,Yadav H,Rampal S,et al.Ethnic variation,epidemiological factors and quality of life impairment associated with dyspepsiain urban Malaysia[J].Aliment Pharmacol Ther,2010,31(10):1141-1151.
[16]王瑞,唐承薇.雌激素与功能性消化不良关系研究[J].中国实用内科杂志,2008,28(6):578-579.
[17]易宗华,程德金,杨雯,等.武汉医学生常见功能性胃肠病患病情况及相关因素研究[J].湖北中医药大学学报,2016,18(6):95-97.
[18]Zhao YF,Ma XQ,Wang R,et al.Epidemiology of functional constipation and comparison with constipation-predominant irritable bowel syndrome:the Systematic Investigation of Gastrointestinal Diseases in China(SILC)[J].Alimentary Pharmacology and Therapeutics,2011,34(8):1020-1029.
[19]Park JW,Cho YS,Lee SY,et al.Concomitant functional gastrointestinal symptoms influence psychological status in Korean migraine patients[J].Gut and Liver,2013,7(6):668-674.
[20]谢晓铿,梁谷,郑琴芳,等.南宁市良庆社区居民FGIDs发生率及相关因素分析[J].广西医学,2013,35(7):831-833.