缬沙坦联合硝苯地平控释片治疗原发性高血压的疗效分析
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摘要
目的探讨选择缬沙坦+硝苯地平控释片对原发性高血压患者进行治疗后获得的临床效果。方法选择该区某院2015年4月—2017年7月收治的82例原发性高血压患者作为实验对象,采用数字奇偶法分组,对照组(41例):硝苯地平控释片;观察组(41例):缬沙坦+硝苯地平控释片;最终就用药结果展开对比。结果同对照组原发性高血压患者治疗总有效率(68.29%)对比,观察组(97.56%)提高程度明显,差异有统计学意义(χ~2=12.403 4,P<0.05)。结论临床选择缬沙坦+硝苯地平控释片对原发性高血压患者进行治疗,可以显著提高其病症疗效、指标表现以及生活质量,最终对于原发性高血压患者综合疗效提高以及疾病快速恢复加以促进。
Objective To study the clinical effect of valsartan and nifedipine controlled release tablets in treatment of primary hypertension. Methods 82 cases of patients with primary hypertension admitted and treated in our hospital from April 2015 to July 2017 were selected and randomly divided into two groups with 41 cases in each, the control group were treated with nifedipine controlled release tablets, while the observation group were treated with valsartan and nifedipine controlled release tablets, and the medication results were compared between groups. Results The total treatment effective rate in the control group and in the observation group was respectively 68.29% and 97.56%, and the improvement degree in the observation group was obvious the difference was statistically significant(χ~2=12.403 4,P<0.05). Conclusion The valsartan and nifedipine controlled release tablets in treatment of primary hypertension can obviously improve the disease curative effect, index manifestations and quality of life, finally it can promote the improvement of comprehensive curative effect and rapid recovery of diseases.
Objective To study the clinical effect of valsartan and nifedipine controlled release tablets in treatment of primary hypertension. Methods 82 cases of patients with primary hypertension admitted and treated in our hospital from April 2015 to July 2017 were selected and randomly divided into two groups with 41 cases in each, the control group were treated with nifedipine controlled release tablets, while the observation group were treated with valsartan and nifedipine controlled release tablets, and the medication results were compared between groups. Results The total treatment effective rate in the control group and in the observation group was respectively 68.29% and 97.56%, and the improvement degree in the observation group was obvious the difference was statistically significant(χ~2=12.403 4,P<0.05). Conclusion The valsartan and nifedipine controlled release tablets in treatment of primary hypertension can obviously improve the disease curative effect, index manifestations and quality of life, finally it can promote the improvement of comprehensive curative effect and rapid recovery of diseases.
引文
[1]黄汉菊,卢建雄,杨月嫦,等.缬沙坦联合氨氯地平治疗社区原发性高血压的临床疗效及安全性[J].中国老年学杂志,2013,33(9):2154-2155.
[2]明少菊,侯超,周芳,等.缬沙坦治疗原发性高血压合并2型糖尿病对血压及肾功能的影响[J].中国老年学杂志,2013,33(18):4421-4422.
[3]罗天勇,李一梅,谢波,等.氨氯地平与缬沙坦分别联合氢氯噻嗪对控制原发性高血压血压的系统评价[J].重庆医学,2015,11(5):673-675.
[4]刘琼,马颖,张琼,等.坎地沙坦、缬沙坦对轻中度原发性高血压降压疗效及心脏重构与舒张功能影响的对比研究[J].中国现代医学杂志,2016,26(17):102-107.
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[6]杜晓马,兰景良,沈昕,等.氨氯地平联合缬沙坦治疗原发性高血压的疗效及对动脉硬化病变的逆转作用[J].中国生化药物杂志,2016,12(1):157-159,162.
[7]王丽,刘妮妮,李健,等.复方缬沙坦氢氯噻嗪片剂治疗缬沙坦单药未达标的轻中度原发性高血压的临床观察[J].中国医药导刊,2015,17(5):483-484,486.
[8]王伟民.阿托伐他汀钙联合缬沙坦对原发性高血压血清炎性因子水平及血管内皮功能的影响[J].中西医结合心脑血管病杂志,2017,15(18):2287-2289.
[9]张赟,许丽雯.缬沙坦联合美托洛尔治疗原发性高血压合并冠心病的疗效观察[J].中西医结合心脑血管病杂志,2016,14(2):173-175.
[10]温丽平.氨氯地平联合缬沙坦治疗老年原发性高血压合并糖尿病的疗效观察[J].中西医结合心脑血管病杂志,2016,14(10):1146-1148.
[11]郭燕青.苯磺酸左旋氨氯地平片联合缬沙坦治疗老年原发性高血压的临床观察[J].中西医结合心脑血管病杂志,2014,15(4):424-425.
[12]童宇星.缬沙坦联合氨氯地平治疗社区老年原发性高血压合并糖尿病的临床效果及安全性分析[J].饮食保健,2017,4(19):72.
[2]明少菊,侯超,周芳,等.缬沙坦治疗原发性高血压合并2型糖尿病对血压及肾功能的影响[J].中国老年学杂志,2013,33(18):4421-4422.
[3]罗天勇,李一梅,谢波,等.氨氯地平与缬沙坦分别联合氢氯噻嗪对控制原发性高血压血压的系统评价[J].重庆医学,2015,11(5):673-675.
[4]刘琼,马颖,张琼,等.坎地沙坦、缬沙坦对轻中度原发性高血压降压疗效及心脏重构与舒张功能影响的对比研究[J].中国现代医学杂志,2016,26(17):102-107.
[5]宁文奇.缬沙坦联合氨氯地平治疗社区老年原发高血压合并糖尿病疗效观察[J].山东医药,2013,53(24):57-58.
[6]杜晓马,兰景良,沈昕,等.氨氯地平联合缬沙坦治疗原发性高血压的疗效及对动脉硬化病变的逆转作用[J].中国生化药物杂志,2016,12(1):157-159,162.
[7]王丽,刘妮妮,李健,等.复方缬沙坦氢氯噻嗪片剂治疗缬沙坦单药未达标的轻中度原发性高血压的临床观察[J].中国医药导刊,2015,17(5):483-484,486.
[8]王伟民.阿托伐他汀钙联合缬沙坦对原发性高血压血清炎性因子水平及血管内皮功能的影响[J].中西医结合心脑血管病杂志,2017,15(18):2287-2289.
[9]张赟,许丽雯.缬沙坦联合美托洛尔治疗原发性高血压合并冠心病的疗效观察[J].中西医结合心脑血管病杂志,2016,14(2):173-175.
[10]温丽平.氨氯地平联合缬沙坦治疗老年原发性高血压合并糖尿病的疗效观察[J].中西医结合心脑血管病杂志,2016,14(10):1146-1148.
[11]郭燕青.苯磺酸左旋氨氯地平片联合缬沙坦治疗老年原发性高血压的临床观察[J].中西医结合心脑血管病杂志,2014,15(4):424-425.
[12]童宇星.缬沙坦联合氨氯地平治疗社区老年原发性高血压合并糖尿病的临床效果及安全性分析[J].饮食保健,2017,4(19):72.