癫狂梦醒汤加减治疗中风后抑郁症临床研究
|
摘要
目的:观察癫狂梦醒汤加减治疗中风后抑郁症(Post stroke depression,PSD)的临床疗效。方法:将80例PSD患者随机分为对照组和治疗组,每组各40例。对照组给予氟哌噻吨美利曲辛片治疗,治疗组服用癫狂梦醒汤加减治疗。观察两组患者的临床疗效,比较两组患者治疗前后汉密顿抑郁量表(HAMD)评分及Barthe1指数评分。结果:治疗组有效率为85.0%,对照组有效率为75.0%,两组患者临床疗效比较,差异具有统计学意义(P<0.05)。两组患者治疗后HAMD及Barthe1指数评分均较治疗前有明显下降,且治疗组下降明显优于对照组,差异均有统计学意义(P<0.05)。结论:癫狂梦醒汤加减能有效治疗中风后抑郁症,改善患者的生活质量。
Objective: To observe the clinical curative effect of Modified Diankuang Mengxing Decoction( MDKMXD) on poststroke depression( PSD). Methods: Eighty patients with PSD were randomly divided into the control group and the treatment group,with 40 cases in each group. The ones in the control group were given Flupentixol and Melitracen Tablets for treatment,while the ones in the treatment group were treated with MDKMXD. Then the clinical curative effects of the two groups were compared/observed,and their HAMD score and Barthel score before and after the treatment were compared. Results: The effective rate of the treatment group was 85. 0%,while that of the control group was 75. 0%; And the difference between them had statistical significance( P < 0. 05). The two group's HAMD score and Barthel score obviously decreased after the treatment; And the reduced degree of the treatment group was obviously better than that of the control group; And the difference between them had statistical significance( P < 0. 05). Conclusion: MDKMXD can effectively treat PSD,and improve the patients' quality of life.
Objective: To observe the clinical curative effect of Modified Diankuang Mengxing Decoction( MDKMXD) on poststroke depression( PSD). Methods: Eighty patients with PSD were randomly divided into the control group and the treatment group,with 40 cases in each group. The ones in the control group were given Flupentixol and Melitracen Tablets for treatment,while the ones in the treatment group were treated with MDKMXD. Then the clinical curative effects of the two groups were compared/observed,and their HAMD score and Barthel score before and after the treatment were compared. Results: The effective rate of the treatment group was 85. 0%,while that of the control group was 75. 0%; And the difference between them had statistical significance( P < 0. 05). The two group's HAMD score and Barthel score obviously decreased after the treatment; And the reduced degree of the treatment group was obviously better than that of the control group; And the difference between them had statistical significance( P < 0. 05). Conclusion: MDKMXD can effectively treat PSD,and improve the patients' quality of life.
引文
[1]安中平,王艳,王景华,等.脑卒中后焦虑和抑郁障碍的影响因素分析[J].中国神经精神疾病杂志,2010,36(9):562-564.
[2]刘泰,钟洁.探析脑卒中后抑郁症的中医病因病机[J].辽宁中医杂志,2011,38(10):1996-1998.
[3]石德志,王桂芳,陈喜恩.首次脑卒中后抑郁症相关因素探讨及治疗[J].中国实用神经疾病杂志,2010,13(13):66-67.
[4]贝政平.内科疾病诊断标准[S].北京:科学出版社,2001:874-882.
[5]中华医学会精神科分会.中国精神障碍分类与诊断标准[S].3版.济南:山东科学技术出版社,2001:87-88.
[6]郭念锋.心理咨询师(二级)[M].北京:民族出版社,2005:174-178.
[7]国家中医药管理局脑病急症协作组.中风病诊断与疗效评定标准[J].北京中医药大学学报,1996,19(1):55.
[8]国家中医药管理局.中医病证诊断疗效标准[S].南京:南京大学出版社,1994:20.
[9]王玉龙.康复评定[M].北京:人民卫生出版社,2000:269.
[10]于兑生.康复医学评价手册[M].北京:华夏出版社,1993:180.
[11]刘宝忠.中医治疗中风后抑郁症的研究近况[J].时珍国医国药,2011,22(10):2570-2572.
[12]刘娟,仲诚.柴胡疏肝散化裁治疗中风后抑郁40例[J].中国中医急症,2012,21(5):788.
[13]盛力.自拟解郁通络汤治疗卒中后抑郁39例[J].辽宁中医杂志,2011,38(2):270-271.
[14]惠建荣,裴建.中风后抑郁的临床评价[C].南阳:世界中联第三届中医、中西医结合老年医学学术大会论文集,2010:131-132.
[15]邢斌,韩天雄.颜德馨内科学术经验薪传[M].北京:中国中医药出版社,2010:115-117.
[16]张红霞.理气解郁法治疗脑卒中后抑郁症28例疗效观察[J].国医论坛,2011,26(3):23.
[17]刘永珍,于逢春,尹静,等.脑卒中后抑郁状态对预后的影响:7年随访[J].中国神经精神疾病杂志,2010,36(5):292-295.
[18]于丽华,于丽荣.中风后3个月抑都症状发生的相关因素的调查研究[J].中国医药指南,2011,9(30):6-7.
[2]刘泰,钟洁.探析脑卒中后抑郁症的中医病因病机[J].辽宁中医杂志,2011,38(10):1996-1998.
[3]石德志,王桂芳,陈喜恩.首次脑卒中后抑郁症相关因素探讨及治疗[J].中国实用神经疾病杂志,2010,13(13):66-67.
[4]贝政平.内科疾病诊断标准[S].北京:科学出版社,2001:874-882.
[5]中华医学会精神科分会.中国精神障碍分类与诊断标准[S].3版.济南:山东科学技术出版社,2001:87-88.
[6]郭念锋.心理咨询师(二级)[M].北京:民族出版社,2005:174-178.
[7]国家中医药管理局脑病急症协作组.中风病诊断与疗效评定标准[J].北京中医药大学学报,1996,19(1):55.
[8]国家中医药管理局.中医病证诊断疗效标准[S].南京:南京大学出版社,1994:20.
[9]王玉龙.康复评定[M].北京:人民卫生出版社,2000:269.
[10]于兑生.康复医学评价手册[M].北京:华夏出版社,1993:180.
[11]刘宝忠.中医治疗中风后抑郁症的研究近况[J].时珍国医国药,2011,22(10):2570-2572.
[12]刘娟,仲诚.柴胡疏肝散化裁治疗中风后抑郁40例[J].中国中医急症,2012,21(5):788.
[13]盛力.自拟解郁通络汤治疗卒中后抑郁39例[J].辽宁中医杂志,2011,38(2):270-271.
[14]惠建荣,裴建.中风后抑郁的临床评价[C].南阳:世界中联第三届中医、中西医结合老年医学学术大会论文集,2010:131-132.
[15]邢斌,韩天雄.颜德馨内科学术经验薪传[M].北京:中国中医药出版社,2010:115-117.
[16]张红霞.理气解郁法治疗脑卒中后抑郁症28例疗效观察[J].国医论坛,2011,26(3):23.
[17]刘永珍,于逢春,尹静,等.脑卒中后抑郁状态对预后的影响:7年随访[J].中国神经精神疾病杂志,2010,36(5):292-295.
[18]于丽华,于丽荣.中风后3个月抑都症状发生的相关因素的调查研究[J].中国医药指南,2011,9(30):6-7.