胸段食管鳞癌患者术后预后影响因素

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英文篇名：Influencing factors of postoperation prognosis of patients with thoracic esophageal squamous cell carcinoma 作者：刘杨 ; 巴玉峰 ; 刘如 ; 贺春语 ; 杨原源 ; 李浩淼 ; 姚志华 ; 王刚成 ; 李定杰 ; 蒋月 英文作者：LIU Yang;BA Yufeng;LIU Ru;HE Chunyu;YANG Yuanyuan;LI Haomiao;YAO Zhihua;WANG Gangcheng;LI Dingjie;JIANG Yue;Department of Radiation Oncology,the Affiliated Cancer Hospital of Zhengzhou University Henan (Cancer Hospital);Department of Thoracic Surgery,the Affiliated Cancer Hospital of Zhengzhou University Henan (Cancer Hospital);Department of Internal Medicine,the Affiliated Cancer Hospital of Zhengzhou University Henan (Cancer Hospital);Department of General Surgery,the Affiliated Cancer Hospital of Zhengzhou University Henan (Cancer Hospital); 关键词：食管鳞癌 ; 根治切除术 ; 术后预后 英文关键词：esophageal squamous cell carcinoma;;radical resection;;postoperation prognosis 中文刊名：HNYK 英文刊名：Journal of Zhengzhou University(Medical Sciences) 机构：郑州大学附属肿瘤医院(河南省肿瘤医院)放疗科;郑州大学附属肿瘤医院(河南省肿瘤医院)胸外科;郑州大学附属肿瘤医院(河南省肿瘤医院)内科;郑州大学附属肿瘤医院(河南省肿瘤医院)普外科; 出版日期：2019-04-03 10:23 出版单位：郑州大学学报(医学版) 年：2019 期：v.54;No.235 基金：河南省科技厅重点科技攻关项目(142102310502);; 河南省卫生厅普通科技攻关项目(201403026);河南省卫生厅科技攻关指导性计划(201304058) 语种：中文; 页：HNYK201904004 页数：4 CN：04 ISSN：41-1340/R 分类号：17-20

摘要

目的:探讨胸段食管鳞癌患者根治切除术后预后的影响因素。方法:收集381例接受根治切除术治疗的胸段食管鳞癌患者的临床、病理与随访资料,采用Kaplan-Meier法进行生存分析,应用Cox回归模型筛选术后预后影响因素。结果:381例患者术后1、2、3 a生存率分别为87. 9%、72. 2%、68. 2%。Cox回归分析结果显示,N分期是胸段食管鳞癌根治切除术后预后的独立危险因素,N1、N2、N3期相较N0期的HR(95%CI)分别为2. 528(1. 345～4. 751)、4. 122(1. 571～10. 815)和8. 387(2. 356～29. 860)。结论:N分期是胸段食管鳞癌根治切除术后预后的独立危险因素。
        Aim: To discuss the influencing factors of prognosis of patients with thoracic esophageal squamous cell carcinoma after radical resection. Methods: Clinicopathological and follow-up data of 381 patients with thoracic esophageal squamous cell carcinoma who underwent radical resection were collected. Kaplan-Meier survival analysis was conducted,and the influencing factors of prognosis were analyzed using Cox regression model. Results: The overall 1-,2-,3-year survival rates were 87. 9%,72. 2%,68. 2%,respectively. Cox analysis showed that N stage was the independent risk factor for the postoperation prognosis( P < 0. 05),the HR( 95% CI) of N1,N2 and N3 stage compared with N0 stage was 2. 528( 1. 345-4. 751),4. 122( 1. 571-10. 815) and 8. 387( 2. 356-29. 860),respectively. Conclusion: N stage is the independent risk factor for the patients with thoracic esophageal squamous cell carcinoma after radical resection.

引文

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