加热不燃烧卷烟烟气主要成分的逐口释放行为
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摘要
为考察加热不燃烧卷烟烟气中主要成分的逐口释放量变化,以两种不同加热方式的加热不燃烧卷烟IQOS和GLO为研究对象,通过改造转盘型吸烟机实现卷烟的逐口抽吸与烟气捕集,建立了烟气中丙三醇、烟碱、水分和主要香气物质的检测方法,并分析了IQOS和GLO在加拿大深度抽吸(HCI)和ISO标准抽吸两种模式下烟气主要成分逐口释放量的变化。结果表明:①采用该方法检测的烟碱、丙三醇和水分的平均回收率≥99.7%,相对标准偏差(RSD)≤5.32%。②随着抽吸口序的增加,在两种抽吸模式下,IQOS烟气中烟碱和丙三醇的释放量均呈现先上升后稳定再下降的趋势;GLO烟气中的烟碱先下降后上升再下降,而丙三醇先上升后下降。③随着抽吸口序的增加,IQOS烟气中水分在ISO抽吸模式下先上升后下降,而在HCI抽吸模式下呈现逐渐下降趋势;GLO烟气中的水分在两种抽吸模式下均呈现逐渐下降趋势。④随着抽吸口序的增加,IQOS烟气中的新植二烯在ISO抽吸模式下逐渐升高,而在HCI模式下先升高后降低;糠醛、羟基丙酮、乙酸和茄酮在两种抽吸模式下先升高后降低,而5-甲基呋喃醛和糠醇逐渐升高。GLO烟气中主要香气物质在两种抽吸模式下呈现两段先上升后下降的趋势。
In order to investigate the puff-by-puff release of main components in aerosols of heat-not-burn(HnB) tobacco products, samples of two commercial HnB tobacco products(IQOS and GLO) with different heating methods were studied with puff-by-puff puffing and aerosol trapping via a modified rotary smoking machine. A method for detecting the glycerol, nicotine, water content and main aroma substances in the HnB aerosols was established, and the puff-by-puff variations of main aerosol components were measured under two puffing regimes(ISO and HCI). The results showed that: 1) The average recovery of nicotine, glycerol and water contents was higher than or equal to 99.7%, and the relative standard deviation was less than or equal to 5.32%. 2) Under the two puffing regimes, the releases of nicotine and glycerol in IQOS aerosols increased first,then stabilized and finally decreased with the proceeding puffs. The release of nicotine in GLO aerosols was more variable, it was increased and then decreased in the first few puffs, then increased and finally decreased again with the remaining puffs, while the glycerol level in GLO increased first and then decreased. 3) With the proceeding puffs, the water content in IQOS aerosols increased first and then decreased under ISO puffing regime, while gradually decreased under HCI puffing regime. The water content in GLO aerosols gradually decreased under the two smoking regimes. 4) With the proceeding puffs, the neophytadiene in IQOS aerosols increased gradually under ISO smoking regime, while increased first and then decreased under HCI smoking regime. The levels of furfural, hydroxy acetone, acetic acid and solanone increased first and then decreased,while 5-methylfurfuraldehyde and furfuryl alcohol levels increased gradually under the two puffing regimes.The main aroma substances in GLO aerosols presented a double increasing first and then decreasing trend under the two puffing regimes.
In order to investigate the puff-by-puff release of main components in aerosols of heat-not-burn(HnB) tobacco products, samples of two commercial HnB tobacco products(IQOS and GLO) with different heating methods were studied with puff-by-puff puffing and aerosol trapping via a modified rotary smoking machine. A method for detecting the glycerol, nicotine, water content and main aroma substances in the HnB aerosols was established, and the puff-by-puff variations of main aerosol components were measured under two puffing regimes(ISO and HCI). The results showed that: 1) The average recovery of nicotine, glycerol and water contents was higher than or equal to 99.7%, and the relative standard deviation was less than or equal to 5.32%. 2) Under the two puffing regimes, the releases of nicotine and glycerol in IQOS aerosols increased first,then stabilized and finally decreased with the proceeding puffs. The release of nicotine in GLO aerosols was more variable, it was increased and then decreased in the first few puffs, then increased and finally decreased again with the remaining puffs, while the glycerol level in GLO increased first and then decreased. 3) With the proceeding puffs, the water content in IQOS aerosols increased first and then decreased under ISO puffing regime, while gradually decreased under HCI puffing regime. The water content in GLO aerosols gradually decreased under the two smoking regimes. 4) With the proceeding puffs, the neophytadiene in IQOS aerosols increased gradually under ISO smoking regime, while increased first and then decreased under HCI smoking regime. The levels of furfural, hydroxy acetone, acetic acid and solanone increased first and then decreased,while 5-methylfurfuraldehyde and furfuryl alcohol levels increased gradually under the two puffing regimes.The main aroma substances in GLO aerosols presented a double increasing first and then decreasing trend under the two puffing regimes.
引文
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[13]YQ-EL/T 2-2017电子烟液烟碱、1,2-丙二醇和丙三醇的测定气相色谱法[S].YQ-EL/T 2-2017 E-liquid-Determination of nicotine,1,2-propylene glycol,glycerol-Gas Chromatographic method[S].
[14]YC/T 345-2010烟草及烟草制品水分的测定气相色谱法[S].YC/T 345-2010 Tobacco and tobacco productsDetermination of water content-Gas Chromatographic method[S].
[15]李超,张健,姜黎,等.不同卷烟纸及滤棒搭配模式对主流烟气部分化学成分逐口抽吸释放量规律的影响[J].纸和造纸,2014,33(12):29-33.LI Chao,ZHANG Jian,JIANG Li,et al.Analysis of the effects of material parameters on puff-by-puff release characteristics of some chemical compounds in aerosol in cigarette smoke[J].Paper and Paper Making,2014,33(12):29-33.
[16]丁超,徐如彦,张洪召,等.卷烟主流烟气粒相物中逐口生物碱含量测定及其递送规律[J].烟草科技,2011(5):59-65.DING Chao,XU Ruyan,ZHANG Hongzhao,et al.Analysis of alkaloids in TPM of mainstream cigarette smoke puff by puff[J].Tobacco Science&Technology,2011(5):59-65.
[17]刘嘉莉,文建辉,庹苏行,等.HS-SPME-GC/MS法测定主流烟气中8种香味成分的逐口释放量[J].烟草科技,2016,49(1):31-37,71.LIU Jiali,WEN Jianhui,TUO Suxing,et al.Puff-by-puff release of 8 aroma compounds in mainstream cigarette smoke as determined by HS-SPME-GC/MS[J].Tobacco Science&Technology,2016,49(1):31-37,71.
[2]张兴伟,邢丽敏,齐义良,等.新型烟草制品未来发展探讨[J].中国烟草科学,2015,36(4):110-116.ZHANG Xingwei,XING Limin,QI Yiliang,et al.Discussion on the development of novel tobacco products[J].Chinese Tobacco Science,2015,36(4):110-116.
[3]窦玉青,沈轶,杨举田,等.新型烟草制品发展现状及展望[J].中国烟草科学,2016,37(5):92-97.DOU Yuqing,SHEN Yi,YANG Jutian,et al.The development and prospect of novel tobacco products[J].Chinese Tobacco Science,2016,37(5):92-97.
[4]李磊,周宁波,屈湘辉.新型烟草制品市场发展及法律监管[J].中国烟草学报,2018,24(2):100-110.LI Lei,ZHOU Ningbo,QU Xianghui.Market development and regulation of novel tobacco products[J].Acta Tabacaria Sinica,2018,24(2):100-110.
[5]周昆,杨继,杨柳,等.加热不燃烧卷烟气溶胶研究进展[J].中国烟草学报,2017,23(5):141-149.ZHOU Kun,YANG Ji,YANG Liu,et al.Research advances related to heat-not-burn cigarette aerosol[J].Acta Tabacaria Sinica,2017,23(5):141-149.
[6]Kogel U,Schlage W K,Martin F,et al.A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with conventional cigarettes[J].Food and Chemical Toxicology,2014,68:204-217.
[7]杨继,杨帅,段沅杏,等.加热不燃烧卷烟烟草材料的热分析研究[J].中国烟草学报,2015,21(6):7-13.YANG Ji,YANG Shuai,DUAN Yuanxing,et al.Investigation of thermogravimetry and pyrolysis behavior of tobacco material in two heat-not-burn cigarette brands[J].Acta Tabacaria Sinica,2015,21(6):7-13.
[8]刘珊,崔凯,曾世通,等.加热非燃烧型烟草制品剖析[J].烟草科技,2016,49(11):56-65.LIU Shan,CUI Kai,ZENG Shitong,et al.Analysis of blend and aerosol composition of two heat-not-burn tobacco products[J].Tobacco Science&Technology,2016,49(11):56-65.
[9]朱浩,席辉,柴国璧,等.温度对加热非燃烧卷烟烟熏香成分释放的影响[J].烟草科技,2017,50(11):33-38.ZHU Hao,XI Hui,CHAI Guobi,et al.Effects of heating temperature on release of smoky aerosol components from heat-not-burn tobacco products[J].Tobacco Science&Technology,2017,50(11):33-38.
[10]胡安福,刘珊,杨君,等.丙二醇对烟叶加热非燃烧状态下烟气释放的影响[J].河南农业大学学报,2016,50(6):818-822.HU Anfu,LIU Shan,YANG Jun,et al.Effects of propylene glycol on tobacco smoke release under heat-not-burn condition[J].Journal of Henan Agricultural University,2016,50(6):818-822.
[11]唐培培,曾世通,刘珊,等.甘油对烟叶热性能及加热状态下烟气释放的影响[J].烟草科技,2015,48(3):61-65.TANG Peipei,ZENG Shitong,LIU Shan,et al.Effects of glycerol on thermal property and smoke release of tobacco leaves under heating[J].Tobacco Science&Technology,2015,48(3):61-65.
[12]韩敬美,刘秀明,张霞,等.电子烟烟雾关键成分逐口释放规律研究[J].中国测试,2017,43(增刊1):63-67.HAN Jingmei,LIU Xiuming,ZHANG Xia,et al.Study on puff-by-puff release of major components in e-cigarette aerosol[J].China Measurement&Test,2017,43(S1):63-67.
[13]YQ-EL/T 2-2017电子烟液烟碱、1,2-丙二醇和丙三醇的测定气相色谱法[S].YQ-EL/T 2-2017 E-liquid-Determination of nicotine,1,2-propylene glycol,glycerol-Gas Chromatographic method[S].
[14]YC/T 345-2010烟草及烟草制品水分的测定气相色谱法[S].YC/T 345-2010 Tobacco and tobacco productsDetermination of water content-Gas Chromatographic method[S].
[15]李超,张健,姜黎,等.不同卷烟纸及滤棒搭配模式对主流烟气部分化学成分逐口抽吸释放量规律的影响[J].纸和造纸,2014,33(12):29-33.LI Chao,ZHANG Jian,JIANG Li,et al.Analysis of the effects of material parameters on puff-by-puff release characteristics of some chemical compounds in aerosol in cigarette smoke[J].Paper and Paper Making,2014,33(12):29-33.
[16]丁超,徐如彦,张洪召,等.卷烟主流烟气粒相物中逐口生物碱含量测定及其递送规律[J].烟草科技,2011(5):59-65.DING Chao,XU Ruyan,ZHANG Hongzhao,et al.Analysis of alkaloids in TPM of mainstream cigarette smoke puff by puff[J].Tobacco Science&Technology,2011(5):59-65.
[17]刘嘉莉,文建辉,庹苏行,等.HS-SPME-GC/MS法测定主流烟气中8种香味成分的逐口释放量[J].烟草科技,2016,49(1):31-37,71.LIU Jiali,WEN Jianhui,TUO Suxing,et al.Puff-by-puff release of 8 aroma compounds in mainstream cigarette smoke as determined by HS-SPME-GC/MS[J].Tobacco Science&Technology,2016,49(1):31-37,71.